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Comparison of two fluid management strategies in acute lung injury
1. Comparison of Two Fluid-Management Strategies in Acute Lung Injury The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network* N Engl J Med, May, 2006;354:2564-75. Presented by ่ๅญๆดช Supervisor ๆฅไฟๆฐ้ซๅธซ ๆฌๆชๅ ไพๅ ง้จๆๅญธไฝฟ็จ ๆชๆกๅ งๆไฝฟ็จไน็ ง็ไน็ๆฌไปๅฑฌๆผๅๆๅ ๅ ฌ้ไฝฟ็จๆ , ้ ็ฒๅพๅๆๅไนๅๆๆๆฌ
18. Protocol Conduct and Instructions 19% 21% Drotrecogin alfa use 32% 37% Systemic corticosteroids 29% 39% At least one blood transfusion 6% 4% Dobutamine use 6% 15% Fluid bolus 41% 10% Received furosemide 4.1 5.1 Protocol instructions per day 88% 91% The rate of compliance with instructions 43.8ยฑ2.5 41.3 ยฑ1.6 The mean time from admission to the ICU to the first protocol instruction. (hours) Conservative Liberal
22. Fluid Balance โ 1576 ยฑ 519 ml 5287 ยฑ 576 ml No shock at baseline, the cumulative seven-day fluid balance 2904 ยฑ 1008 ml 10,138 ยฑ 922 ml Shock at baseline, the cumulative seven-day fluid balance Conservative Liberal