biofilm

1. Biofilm, Biofouling
Dr Hui Yew Woh

2. Biofilm
 are a collective of one or more types of microorganisms that can grow on
many different surfaces.
 Microorganisms that form biofilms include bacteria, fungi and protists
 Biofilms are now believed to be the primary mode of existence for bacteria in
aqueous environments.
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3. Formation

4. Characteristic of Biofilms
 has little to none of original planktonic characteristics
 resistant to various antibiotics and antimicrobial agents
 can coordinate behavior via intercellular "communication" using
biochemical signaling molecules
 Enhanced scavenging of nutrients
 Higher DNA synthesis and RNA turnover rates
 Enhanced virulence
 Greater local diversity
 Physical protection and stabilization

5. Effects of biofilm
 dissemination of infection via
transplants or oral biofilms
 cavity
 biofouling

7. summary of action Against biofilms

8. Biofilm on ‘biological’ surface
 Microbial biofilms readily develop on all types of devices, urinary,
endotracheal, intravenous, and other types of catheters and implants
inserted into more than 25% of patients during hospitalization.
 harsh and potentially fatal consequences of microbial biofilm infections

9. Treatment/prevention
 coating of medical material
 sound waves or heat pulses

10. Biofouling
 these organisms attach themselves to the hulls of ships or boats, their
presence hastens the breakdown of the outer finish of the hull as well as
detracting from the performance of effected vessel
 transport marine organisms native to one area of the world to other areas,
where the native marine life, including vital food sources, might be
endangered by the introduction of new species or varieties of organisms

11. Treatment
 coating of biocide agent and adhesion surface
 sonicator