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CHILD WITH AN EMPTY SCROTUM 
A PROBLEM ORIENTED APPROACH
CHILD WITH AN EMPTY SCROTUM 
A PROBLEM ORIENTED APPROACH 
Dr.B.SELVARAJ MS;Mch;FICS; 
NEONATAL & PEDIATRIC SURGEON 
MELAKA MANIPAL MEDICAL COLLEGE 
MELAKA– 75150 MALAYSIA 
M 
M 
M 
C
CHILD WITH AN EMPTY SCROTUM 
Recognise various conditions 
Clinch correct diagnosis 
Appropriate investigations 
Timely surgical referral 
M 
M 
M 
C 
A PROBLEM ORIENTED APPROACH 
OBJECTIVES
CHILD WITH AN EMPTY SCROTUM 
UNDESCENDED 
TESTIS 
ECTOPIC TESTIS 
RETRACTILE 
TESTIS 
POST-TORSION 
ATROPHY 
M 
M 
M 
C 
CAUSES
Embryology Of Testicular Descend 
Primitive gonad in urogenital ridge turns into 
testis by gene in short arm of Y 
chromosome; Early Testis3 hormones 
TestosteroneFrom Leydig cells CSL 
regression 
Mullerian inhibiting substance from 
Sertolli cells Mullerian duct regression 
Insulin- like3 hormone Thickening of 
caudal gubernaculum holds testis close to 
inguinal abdominal wall  Relative 
descend of testis 
M 
M 
M 
C 
8 to 15 Wks of Gestation- Transabdominal Phase
Embryology Of Testicular Descend 
28 to 35 Wks of Gestation- Inguinoscrotal Phase 
At 25 Wks Processus vaginalis 
elongates into gubernaculum 
Distal end of gubernaculum elongates 
and reach scrotum between 30- 35 wks 
Then testis descend through patent 
processus vaginalis 
Testosterone GFN CGRP 
Migration of gubernaculum along with 
testis to scrotum 
M 
M 
M 
C
Various Stages Of 
Testicular Descend 
M 
M 
M 
C
Classification Of Cryptorchidism 
(Hidden Testis) 
M 
M 
M 
C
UNDESCENDED TESTIS 
ETIOLOGY 
Anatomical 
Endocrine 
Iatrogenic 
• Short spermatic 
artery 
•Retroperitoneal 
Adhesion 
•Malfunctioning 
Gubernaculum 
•Narrow inguinal 
ring/ canal 
• Pituitary 
deficiency 
•Testosterone 
deficiency 
•Post Herniotomy 
M 
M 
M 
C
UNDESCENDED TESTIS 
Testicular descend is arrested in it’s normal path 
Rt side60%; Lt side30%;Bilateral10% 
Premies30%; Full term Neonates 4to5%; 
3Month infant1to2%; 1Yr olds0.3% 
Empty  poorly developed Scrotum 
M 
M 
M 
C
UNDESCENDED TESTIS 
Always associated with patent processus vaginalis 
Inguinal Hernia 
If testis is palpable in groin do Milking Manuver to 
R/O Retractile testis 
Palpate perineum  upper thigh to R/O Ectopic Testis 
If testis is impalpable needs further workup to 
localise the testis 
M 
M 
M 
C
UNDESCENDED TESTIS 
M 
M 
M 
C
UNDESCENDED TESTIS 
Milking Manuver 
M 
M 
M 
C
UNDESCENDED TESTIS 
Complications 
M 
M 
M 
C 
TRAUMA 
TORSION 
TESTICULAR 
MALIGNANCY 
PSYCHOLOGICAL 
PROBLEMS 
INFERTILITY
UNDESCENDED TESTIS 
Postnatal Germ Cell Development 
M 
M 
M 
C
UNDESCENDED TESTIS 
Infertility  Cancer 
Scrotum 4*c  than core body temperature Ideal for 
spermatogenesis 
Transformation of Neonatal gonocyte to type A 
Spermatogonium is impaired 
This transformation occurs at 3to 6 months of age 
Dysplastic gonocyte is the cause for malignant 
transformation in early adulthood  for infertility 
M 
M 
M 
C
UNDESCENDED TESTIS 
Workup 
In Bilateral Impalpable Testis: HCG stimulation test to 
confirm presence of testis 
To localise testis the Gold standard is Laparoscopy 
Diagnostic  Therapeutic 
USG of Groin  Abdomen 
CT Scan Groin  Abdomen 
MRI of Abdomen 
M 
M 
M 
C
UNDESCENDED TESTIS 
Management 
M 
M 
M 
C
UNDESCENDED TESTIS 
INGUINAL ORCHIDOPEXY 
M 
M 
M 
C
UNDESCENDED TESTIS 
INGUINAL ORCHIDOPEXY 
M 
M 
M 
C
Algorithm for Impalpable Testis 
M 
M 
M 
C
UNDESCENDED TESTIS 
DIAGNOSTIC LAPAROSCOPY 
Vas and Testicular vessels 
entering the internal inguinal ring 
Canalicular UDT 
Blind ending Vas and Testicular 
vessels 
Anorchia (Vanishing Testis) 
M 
M 
M 
C
UNDESCENDED TESTIS 
Laparoscopic Fowler Stephens 
M 
M 
M 
C
UNDESCENDED TESTIS 
Laparoscopic Fowler Stephens 
M 
M 
M 
C 
Prentiss Maneuver
UNDESCENDED TESTIS 
Complications of Orchidopexy 
Damage to Testicular vessels Testicular Atrophy 
Damage to Vas Deferens Infertility 
Retraction of Testis out of Scrotum 
Hemorrhage 
Wound infection 
M 
M 
M 
C
ECTOPIC TESTIS 
 Testis after coming out of external inguinal ring 
has migrated into an abnormal location 
 Sites of ectopic testis are 
- Superficial inguinal pouch 
- Perineum 
- Pre penile 
- Opposite side scrotum- crossed ectopic 
- Femoral triangle 
 Diagnosis is obvious  Orchidopexy is easy 
M 
M 
M 
C
Sites of UDT  Ectopic Testis 
M 
M 
M 
C
ECTOPIC TESTIS- Perineal 
M 
M 
M 
C
RETRACTILE TESTIS 
Testis can be manipulated into 
scrotum 
Testis is pulled and held high by 
overactive cremastric muscle 
Descends into scrotum whenever 
child is relaxed/ sleeping 
By puberty testis grow in size  
remain in scrotum 
No intervention is needed 
M 
M 
M 
C
CHILD WITH AN EMPTY SCROTUM 
www.themegaller 
y.com
CHILD WITH AN EMPTY SCROTUM 
www.themegaller 
y.com
TAKE HOME MESSAGE 
Child should be operated between 6months to 1year 
Undue delay in surgery carries the risk of infertility 
and malignancy in adult life 
Hormone therapy may be tried between 3to 6 
months 
Retractile testis should not be operated 
Intra abdominal testis is best managed with 
Laparoscopy 
M 
M 
M 
C
Cryptorchidism--(Undescended testis)

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Cryptorchidism--(Undescended testis)

  • 1. CHILD WITH AN EMPTY SCROTUM A PROBLEM ORIENTED APPROACH
  • 2. CHILD WITH AN EMPTY SCROTUM A PROBLEM ORIENTED APPROACH Dr.B.SELVARAJ MS;Mch;FICS; NEONATAL & PEDIATRIC SURGEON MELAKA MANIPAL MEDICAL COLLEGE MELAKA– 75150 MALAYSIA M M M C
  • 3. CHILD WITH AN EMPTY SCROTUM Recognise various conditions Clinch correct diagnosis Appropriate investigations Timely surgical referral M M M C A PROBLEM ORIENTED APPROACH OBJECTIVES
  • 4. CHILD WITH AN EMPTY SCROTUM UNDESCENDED TESTIS ECTOPIC TESTIS RETRACTILE TESTIS POST-TORSION ATROPHY M M M C CAUSES
  • 5. Embryology Of Testicular Descend Primitive gonad in urogenital ridge turns into testis by gene in short arm of Y chromosome; Early Testis3 hormones TestosteroneFrom Leydig cells CSL regression Mullerian inhibiting substance from Sertolli cells Mullerian duct regression Insulin- like3 hormone Thickening of caudal gubernaculum holds testis close to inguinal abdominal wall Relative descend of testis M M M C 8 to 15 Wks of Gestation- Transabdominal Phase
  • 6. Embryology Of Testicular Descend 28 to 35 Wks of Gestation- Inguinoscrotal Phase At 25 Wks Processus vaginalis elongates into gubernaculum Distal end of gubernaculum elongates and reach scrotum between 30- 35 wks Then testis descend through patent processus vaginalis Testosterone GFN CGRP Migration of gubernaculum along with testis to scrotum M M M C
  • 7. Various Stages Of Testicular Descend M M M C
  • 8. Classification Of Cryptorchidism (Hidden Testis) M M M C
  • 9. UNDESCENDED TESTIS ETIOLOGY Anatomical Endocrine Iatrogenic • Short spermatic artery •Retroperitoneal Adhesion •Malfunctioning Gubernaculum •Narrow inguinal ring/ canal • Pituitary deficiency •Testosterone deficiency •Post Herniotomy M M M C
  • 10. UNDESCENDED TESTIS Testicular descend is arrested in it’s normal path Rt side60%; Lt side30%;Bilateral10% Premies30%; Full term Neonates 4to5%; 3Month infant1to2%; 1Yr olds0.3% Empty poorly developed Scrotum M M M C
  • 11. UNDESCENDED TESTIS Always associated with patent processus vaginalis Inguinal Hernia If testis is palpable in groin do Milking Manuver to R/O Retractile testis Palpate perineum upper thigh to R/O Ectopic Testis If testis is impalpable needs further workup to localise the testis M M M C
  • 13. UNDESCENDED TESTIS Milking Manuver M M M C
  • 14. UNDESCENDED TESTIS Complications M M M C TRAUMA TORSION TESTICULAR MALIGNANCY PSYCHOLOGICAL PROBLEMS INFERTILITY
  • 15. UNDESCENDED TESTIS Postnatal Germ Cell Development M M M C
  • 16. UNDESCENDED TESTIS Infertility Cancer Scrotum 4*c than core body temperature Ideal for spermatogenesis Transformation of Neonatal gonocyte to type A Spermatogonium is impaired This transformation occurs at 3to 6 months of age Dysplastic gonocyte is the cause for malignant transformation in early adulthood for infertility M M M C
  • 17. UNDESCENDED TESTIS Workup In Bilateral Impalpable Testis: HCG stimulation test to confirm presence of testis To localise testis the Gold standard is Laparoscopy Diagnostic Therapeutic USG of Groin Abdomen CT Scan Groin Abdomen MRI of Abdomen M M M C
  • 19. UNDESCENDED TESTIS INGUINAL ORCHIDOPEXY M M M C
  • 20. UNDESCENDED TESTIS INGUINAL ORCHIDOPEXY M M M C
  • 21. Algorithm for Impalpable Testis M M M C
  • 22. UNDESCENDED TESTIS DIAGNOSTIC LAPAROSCOPY Vas and Testicular vessels entering the internal inguinal ring Canalicular UDT Blind ending Vas and Testicular vessels Anorchia (Vanishing Testis) M M M C
  • 23. UNDESCENDED TESTIS Laparoscopic Fowler Stephens M M M C
  • 24. UNDESCENDED TESTIS Laparoscopic Fowler Stephens M M M C Prentiss Maneuver
  • 25. UNDESCENDED TESTIS Complications of Orchidopexy Damage to Testicular vessels Testicular Atrophy Damage to Vas Deferens Infertility Retraction of Testis out of Scrotum Hemorrhage Wound infection M M M C
  • 26. ECTOPIC TESTIS Testis after coming out of external inguinal ring has migrated into an abnormal location Sites of ectopic testis are - Superficial inguinal pouch - Perineum - Pre penile - Opposite side scrotum- crossed ectopic - Femoral triangle Diagnosis is obvious Orchidopexy is easy M M M C
  • 27. Sites of UDT Ectopic Testis M M M C
  • 29. RETRACTILE TESTIS Testis can be manipulated into scrotum Testis is pulled and held high by overactive cremastric muscle Descends into scrotum whenever child is relaxed/ sleeping By puberty testis grow in size remain in scrotum No intervention is needed M M M C
  • 30. CHILD WITH AN EMPTY SCROTUM www.themegaller y.com
  • 31. CHILD WITH AN EMPTY SCROTUM www.themegaller y.com
  • 32. TAKE HOME MESSAGE Child should be operated between 6months to 1year Undue delay in surgery carries the risk of infertility and malignancy in adult life Hormone therapy may be tried between 3to 6 months Retractile testis should not be operated Intra abdominal testis is best managed with Laparoscopy M M M C