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Vaccination and Medication.pptx

  1. Vaccination and Medication in Poultry Dr. Atif Rehman Ph.D Poultry Science
  2. What is Vaccine? •A vaccine is a biological preparation that improves immunity to a particular disease •A vaccine typically contains an agent that resembles a disease-causing microorganism
  3. Vaccine vs Bacterin
  4. How Vaccine Prepared •It is often made from weakened or killed forms of the microbe,
  5. Types of Vaccines •Live •Attenuated •Killed/ Inactivated
  6. Live vs Killed Vaccines
  7. Why Vaccination is necessary? •To induce high MDA (Maternally Derived Antibodies) •To prevent & control the disease •To enhance the immune status
  8. Vaccinal Immunity •Live vaccine peak response after 10 days •Killed after 21 days
  9. What is required for good immune response?
  10. Vaccine and Immunosuppressive Diseases Don’t vaccine during immunosuppressive disease i.e. 1. IBD 2. CIA 3. MD 4. Coccidiosis
  11. Characteristics of ideal Vaccine •Safe •Efficacious • Pure
  12. Vaccine Transportation •Prevent Temperature Fluctuations •4°C for live vaccines, •-80oC for cell associated Marek’s •Prevent from sunlight
  13. General procedures •Timing •Doses and types •Record all vaccination procedures •Don’t vaccine during stress, disease, immuno suppression, off-feeding etc.
  14. Vaccination at Farm •Water •Spray •Eye drop •S/C or I/M
  15. Water Vaccination 5.5-7.5 pH Water deprivation (Max. 1 hour) 1-2 hours Ingestion time No chlorination before 72 hours 2.5 g skimmed milk/ liter water
  16. . Add liquefied vaccine in water Add skim milk (2.5 g/ l) 20 minutes before mixing Add diluent to vaccine vial and shake gently
  17. Vaccine through Injection
  18. I/M, Breast
  19. S/C
  20. Medication
  21. Purpose •Prevention •Cure •Growth Promoter
  22. Commonly Used Medicines •Antibiotics •Coccidiostates/ Anticoccidials •Liver tonics
  23. Commonly Used Antibiotics in Poultry • Lincomycin • Enramycin • Avilamycin • Penicillin • Amoxicillin • Colistin • Tetracyclin • Doxycycline • Tylocin • Tilmicosin • Tiamulin • Spiramycin • Enrofloxacin • Floramphenicol
  24. Coccidiostates
  25. Coccidiosis •Protozoal disease of poultry with high mortality •Mostly affect birds of 3-6 weeks of age •Broilers are more susceptible than layers •Intestinal coccidiosis mostly occurs in older birds •Caused by 9 Eimeria spp
  26. Coccidiosis Type Caused by Intestinal E. necatrix, E. maxima, E. mivati, E. acervulina Caecal E. tenella and to some extent E. necatrix Rectal E. brunetti
  27. Coccidiostates •Used to prevent replication and growth of coccidial population •Prophylaxis is important that treatment •Normally used in feed at preventive doses
  28. Categories of Coccidiostates •Synthetic •Ionophores or polyether antibiotics •Mixed (combination of different anticoccidials from same or different groups)
  29. Dosage Coccidiostate Dosage (%) Amprolium 0.0125 Nicarbazine 0.0125 Monensin 0.01-0.0121 Maduramicin 5-6 ppm Salinomycine 0.01-0.0121 Lasalocid 0.005-0.0075 Clopidol (Pyridionol) 125 ppm Buquinolate (Quinolones) 0.00825 Robenidine 0.0066 Sulphaquinoxaline 0.025-0.033
  30. Liver Tonics •Betaine •Choline •Inositol •Silymarine