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MYCIN
Dr. C.V. Suresh Babu
(CentreforKnowledgeTransfer)
institute
What is MYCIN?
 MYCIN, an early expert system, or artificial intelligence (AI) program,
designed to assist physicians in the diagnosis of and therapy selection for
treating patients with bacterial and blood infections.
 The system was actually not used in clinical practice, but it constitutes an
excellent early example of a digital expert system and a precursor to much
more sophisticated machine learning and knowledge base systems years later.
(CentreforKnowledgeTransfer)
institute
When and Where?
 In 1972 work began on MYCIN at Stanford University in California
(CentreforKnowledgeTransfer)
institute
The Name
 MYCIN is not an acronym.
 The name was chosen after attempts at finding a suitable acronym failed.
 The name is the common suffix associated with many antimicrobial agents.
 Examples of aminoglycosides include
 gentamicin,
 tobramycin,
 neomycin, and
 streptomycin
(CentreforKnowledgeTransfer)
institute
How?
 MYCIN would attempt to diagnose patients based on reported symptoms and
medical test results.
 The program could request further information concerning the patient, as
well as suggest additional laboratory tests, to arrive at a probable diagnosis,
after which it would recommend a course of treatment.
 If requested, MYCIN would explain the reasoning that led to its diagnosis and
recommendation.
(CentreforKnowledgeTransfer)
institute
Features
 In addition to the consultation system itself, MYCIN contains an explanation
system which can answer simple English questions in order to justify its advice
or educate the user.
 Much of MYCIN's power derives from the modular, highly stylized nature of
these decision rules, enabling the system to dissect its own reasoning and
allowing easy modification of the knowledge base.
(CentreforKnowledgeTransfer)
institute
Production Rules
 The system's knowledge is encoded in the form of some 600 production rules
which embody the clinical decision criteria of infectious disease experts.
 Users would enter answers to a series of “yes” or “no” questions and short
answer questions, and the program would eventually choose a weighted
probability for a diagnosis.
(CentreforKnowledgeTransfer)
institute
Limitations
 Part of the limitation of this early program was simply computing power –
because the program was estimated to take up to half an hour to get through
in a clinical environment, it was not considered effective enough to replace
human diagnosis at the time.
 Ethical questions also contributed to the decision not to use Mycin for clinical
diagnosis.
(CentreforKnowledgeTransfer)
institute
Conclusion
 Mycin has proven to be a stepping stone to more modern systems and
described in a book on rule-based expert systems by B. G. Buchanan and E. H.
Shortliffe as “the granddaddy of them all” in terms of early artificial
intelligence for machine learning systems

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Mycin

  • 2. (CentreforKnowledgeTransfer) institute What is MYCIN?  MYCIN, an early expert system, or artificial intelligence (AI) program, designed to assist physicians in the diagnosis of and therapy selection for treating patients with bacterial and blood infections.  The system was actually not used in clinical practice, but it constitutes an excellent early example of a digital expert system and a precursor to much more sophisticated machine learning and knowledge base systems years later.
  • 3. (CentreforKnowledgeTransfer) institute When and Where?  In 1972 work began on MYCIN at Stanford University in California
  • 4. (CentreforKnowledgeTransfer) institute The Name  MYCIN is not an acronym.  The name was chosen after attempts at finding a suitable acronym failed.  The name is the common suffix associated with many antimicrobial agents.  Examples of aminoglycosides include  gentamicin,  tobramycin,  neomycin, and  streptomycin
  • 5. (CentreforKnowledgeTransfer) institute How?  MYCIN would attempt to diagnose patients based on reported symptoms and medical test results.  The program could request further information concerning the patient, as well as suggest additional laboratory tests, to arrive at a probable diagnosis, after which it would recommend a course of treatment.  If requested, MYCIN would explain the reasoning that led to its diagnosis and recommendation.
  • 6. (CentreforKnowledgeTransfer) institute Features  In addition to the consultation system itself, MYCIN contains an explanation system which can answer simple English questions in order to justify its advice or educate the user.  Much of MYCIN's power derives from the modular, highly stylized nature of these decision rules, enabling the system to dissect its own reasoning and allowing easy modification of the knowledge base.
  • 7. (CentreforKnowledgeTransfer) institute Production Rules  The system's knowledge is encoded in the form of some 600 production rules which embody the clinical decision criteria of infectious disease experts.  Users would enter answers to a series of “yes” or “no” questions and short answer questions, and the program would eventually choose a weighted probability for a diagnosis.
  • 8. (CentreforKnowledgeTransfer) institute Limitations  Part of the limitation of this early program was simply computing power – because the program was estimated to take up to half an hour to get through in a clinical environment, it was not considered effective enough to replace human diagnosis at the time.  Ethical questions also contributed to the decision not to use Mycin for clinical diagnosis.
  • 9. (CentreforKnowledgeTransfer) institute Conclusion  Mycin has proven to be a stepping stone to more modern systems and described in a book on rule-based expert systems by B. G. Buchanan and E. H. Shortliffe as “the granddaddy of them all” in terms of early artificial intelligence for machine learning systems