Robb Wolf, B.S. presenting at the Ancestral Health Symposium 2012 (AHS12)
City Zero: How Markets and Evolution Can Revolutionize Medicine
Abstract:
An investigation of how markets influence medical innovation and a case history of how the Ancestral Health model has been implemented at the city level.
Bio:
Robb Wolf, a former research biochemist, is the New York Times Best Selling author of The Paleo Solution: The Original Human Diet.
Robb has functioned as a review editor for the Journal of Nutrition and Metabolism, is co-founder of the nutrition and athletic training journal, The Performance Menu, and co-owner of NorCal Strength & Conditioning, one of the Men's Health Top 30 Gyms in America.
11. Quick Recap:
When technology advances goods & services improve, costs
decrease.
We know more about biology, genetics and pathology than ever.
But…
Medical costs increase
Quality of care decreases
Disease rates increase
HOW can this possibly be So? What are we doing wrong?
12. On the Job Selection Pressure:
Cops were dying
UNLV police officers
3 Cardiac events in 1 year
Costs to retire an officer-$1.2
Real costs 1ox this amount
13. Founded in 1993
Initially Orthopedic risk assessment
Could Metabolic risk assessment save lives (and money)?
14. In the Beginning
Standard blood work
HDL, LDL, total chol, Trig’s
Framingham scores
American Heart Association diet
Results were dismal, often times worse than no
intervention!
15. Paradigm Shift
Low Carb
National Lipid Association
NMR testing via Liposcience Labs
30. Pilot Study
Number of participants 33
Program costs-$1000
Program savings
20/1 ROI $22million saved (prorated over 20 year period)
31. That’s great, But…
Are we STILL treating symptoms?
Is elevated LDL-P a symptom of intestinal permeability
and systemic inflammation?
What is the mechanism of action for statins and
metformin?
35. “The protective effects of the metformin treatment on the
onset of fructose-induced non-alcoholic fatty liver disease
(NAFLD) were associated with a protection against the
loss of the tight junction proteins occludin and zonula
occludens 1 in the duodenum of fructose-fed mice and the
increased translocation of bacterial endotoxin found in
mice only fed with fructose.”
36. “…Taken together, these data suggest that
metformin not only protects the liver from the
onset of fructose-induced NAFLD through
mechanisms involving its direct effects on
hepatic insulin signaling but rather through
altering intestinal permeability and
subsequently the endotoxin-dependent
activation of hepatic Kupffer cells.”
38. Addition of the Paleo Template
Intestinal permeability and autoimmunity
Integrating screening for:
Intestinal permeability
Autoimmunity
39. What’s next
Program encompassing all Reno Police & Fire
With inclusion of paleo/AH models of inflammation
Spread program to global audience
45 Municipalities: Europe, AU, NZ, US
Consolidate data collection via Specialty Health
Release Health care provider education
Gyms, allied HC, MD’s
Develop health insurance company pushing HSA’s and
referral network to gyms, physicians & allied HCP’s
CSU Grad in 1998-vegetarianBecame sick, found the paleo concept. Fixed my problemsResearch biochemist-Lipid metabolism, research fellowship with Loren CordainOpened gym, spoke internationally, wrote book, all on Paleo Nutrition & Lifestyle
We know more about biology, genetics pathology than EVER…but yet
Primary driver in healthcare related costs is obesity & related complications
Managed Care magazine.comUpper bound predicts 1 in 3 Americans with diabetes
Current prices range $600-1,000 before inflation!What if we had thee right theory operating with our best technology?
Risk manager from UNLV-3 significant CV eventsOff books costs 10X
Comprehensive survey of UNR police dept, looking for at risk cops
Results from screening were confusing as folks who looked fit were diabetic, insulin resistant etc. Todrenwick original guy looked healthy and fit
Nutritional approach was obvious problem. Low carb (ala Gary Taubes) were implemented
NMR normal
Discordance 134 YO male, LDL would not flag normal testing, although clear Insulin resistance via trig/HDL ratioTrig 362
LDL-P is 2,231, desirable is less than 1,000Triglycerides 362
Poor with hepatic LDL receptorsTend to become oxidizedBUT! High affinity for LPS!
Dead Man Walking
CD14 is a surface antigen of monocytes and immune cells. Processed by Kupfer cells, release of TNF
Ed Greenwald, circa 1930Robert Braidwood
Dear friend of the Greenwald familyPioneer in the archeological study of the transition from HG to agricultureCreated lifelong fascination in evolution and science for Dr. Greenwald