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UNIVERSITY OF GLASGOW
Class III Malocclusion
Personal notes
Mohammed Almuzian
2/20/2013
……………………………………….
Mohammed Almuzian, University of Glasgow, 2013 1
Table of Contents
Definition......................................................................................................... 5
Incidence ......................................................................................................... 5
Classification ................................................................................................... 6
Aetiology......................................................................................................... 6
Features of Class III.......................................................................................... 7
A. Skeletal features ........................................................................................ 7
B. Soft tissues features ................................................................................... 8
C. Dental features .......................................................................................... 8
D. Displacements........................................................................................... 8
E. Facial growth ............................................................................................ 8
IOTN and class III.......................................................................................... 11
Crossbite (2.c, 3.c, 4.c) ................................................................................... 12
Growth status assessment for class III patients ................................................. 12
Monitoring the growth of mandible ................................................................. 13
Differentiation between mandibular prognathism & maxillary deficiency ......... 14
Treatment options for class III malocclusion.................................................... 16
Mohammed Almuzian, University of Glasgow, 2013 2
Factors influencing treatment options .............................................................. 16
Summary about treatment strategies according to dental age ............................ 17
Reasons for early treatment of class 3 malocclusions ....................................... 20
Orthopaedic treatment option.......................................................................... 20
Effect of orthopaedic appliance in class III maloculsion ................................... 20
Positive factors for orthopaedic treatment ........................................................ 21
Types of orthopaedic treatment in class III malocclusion.................................. 22
1. Protraction HG........................................................................................ 22
Definition....................................................................................................... 22
History........................................................................................................... 22
Indications ..................................................................................................... 22
Timing........................................................................................................... 24
Effects ........................................................................................................... 24
Protraction face mask system.......................................................................... 25
Evidence based short term effectiveness of PH ................................................ 29
Evidence based long term effectiveness of PH................................................. 29
2. Chin caps................................................................................................ 36
Types: occipital pull, used for patients with mandibular prognathism or
vertical pull, used for patients with increased anterior face height ..................... 36
Mohammed Almuzian, University of Glasgow, 2013 3
Best patient for Chin cup therapy .................................................................... 36
Ko et al (2004) ............................................................................................... 36
The effects of chincup therapy ........................................................................ 37
(Thilander 1963)............................................................................................. 37
3. Reverse chin cup therapy ......................................................................... 37
4. Bone anchored orthopaedic appliance (Bollard miniplates, PFH supported
with miniplates).............................................................................................. 38
5. Shapiro and Kokich 1984 used the same idea by inducing artificial ankylosis
and use the ankylosed teeth as anchor.............................................................. 39
6. Functional appliances .............................................................................. 39
Camouflage (dental compensation for mild cases)............................................ 41
Indications ..................................................................................................... 41
Techniques of camoflagable treatments ........................................................... 42
1. Non extraction......................................................................................... 42
2. Extraction: .............................................................................................. 42
Orthognathic surgery options .......................................................................... 45
The types of surgery most frequently used are the following............................. 45
Intraoperative complications of the mandibular ramus surgery ......................... 46
Mohammed Almuzian, University of Glasgow, 2013 4
What Factors need to be taken into Account When Planning a surgical treatment
for class III cases............................................................................................ 47
1. Planning the type of surgery..................................................................... 47
2. The Pre-Surgical Orthodontics in Class III?.............................................. 47
What Are the Aims of the Pre-Surgical Orthodontics?...................................... 47
Borderline Camouflage/ Orthognathic Surgery Patients.................................... 48
Summary of the evidences .............................................................................. 49
Mohammed Almuzian, University of Glasgow, 2013 5
Class III malocclusion
Definition
 BSI 1982 defined class III incisor relationship as ‘’the lower incisal edge lies
anterior to the cingulum plateau of the the upper incisors, British Standards
Institute, 1983
 The term ‘pseudo-classIII’ has been coined for this situation where an
anterior displacement masking what is in fact an underlying skeletal class I base
relationship.
Incidence
1. Class III prevalence in white populations
 3% UK (Foster & Day, 1974)
 5% (Jones & Oliver, 2000)
 5% UK (Todd and Dodd 1975)
2. Class III prevalence in Asian populations
 4-14% in Asian (Lew 1993)
3. Dental anterior crossbite
 Anterior crossbitein 10% of children (1993 Child Dental Health Survey)
Mohammed Almuzian, University of Glasgow, 2013 6
Classification
Lin (2007) divides class 3 malocclusion into three categories according to the
following definitions:
1. True class 3, anterior crossbitecases with bilateral buccal occlusions in class
III.
2. Class 3 subdivision, anterior crossbitecases with one of the bilateral buccal
occlusions in class 1 and the other in class 3.
3. Pseudo class 3, bilateral class 1 buccal occlusions and majority of teeth in
anterior crossbite. The pseudo class 3 malocclusion is often due to collapse of the
arch perimeter resulted from:
Caries in some Eastern societies (caries collapse)
TSD or small, missing or impacted or palatal positioning of the upper teeth
(perimeter-collapse).
Aetiology
1. Skeletal :
A. Environmental
 Airway problems like enlarged tonsils & nasal blockage,
 Scaring from CLP as a result of surgical repair
 Hormonal like in acromegaly.
Mohammed Almuzian, University of Glasgow, 2013 7
 Some syndromes caused by environmental as well as genetic reasons such as
Crouzons, Aperts, and Cleidocranial dysostosis.
B. Genetic (Litton et al 1970). 1/3 of patients with severe class III have a
parent with class III problems but there is no detected autosomal dominant or
recessive method of transmission.
2. Soft tissue: the ST indeed my act to reduce the severity of CLIII, Lower
incisor retroclination is adaptive due to soft tissue forces and tongue might
procline ULS. Exception in high angle case when there is tongue to lower lip seal
and macroglosia that worsen the CLIII.
3. Dental factors:
 Rarely ULS retroclination and LLS proclination.
 Hypodontia or microdontia in the upper arch
 Impacted upper teeth
4. Habits: tongue to lower lip seal and macroglosia that worsen the CLIII.
Features of Class III
A. Skeletal features
 Cranial base features
 AP relationship
 Vertical relationship
 Transverse relationship
Mohammed Almuzian, University of Glasgow, 2013 8
 Cephalometric skeletal values
B. Soft tissues features
C. Dental features
D. Displacements
E. Facial growth
In details
F. Skeletal features
1. Cranial base features:
 Short cranial baselength.
 Decrease cranial baseangle resulting in forwards position of mandible.
2. AP relationship
 Mainly skeletal class 3 base relationships but it could be Class I or even class II
skeletal base.
 Guyer, Ellis, Behrents and McNamara (1986) 55% of class 3 malocclusions
had maxillary deficiency as one of the components of the malocclusion.
Mandibular prognathsim in 45% of cases.
3. Vertical relationship
Guyer, Ellis, Behrents and McNamara (1986), 59% of class 3 malocclusions had
reduced or neutral lower facial heights and that 41% had increased lower facial
heights.
Mohammed Almuzian, University of Glasgow, 2013 9
4. Transverse relationship
 The maxillary skeletal base widths were (statistically) significantly smaller in the
class 3 than in the class 1group (Chen et al 2008)
 Skeletal asymmetries, particularly in conjunction with mandibular prognathsim,
are also relatively common in class III malocclusions (Severt and Proffit, 1997).
5. Cephalometric skeletal values
 Reduced cranial base angle
 Increased saddle angle
 Obtuse gonial angle
 Reduced ANB
 Normal or increase MMP angle and lower face height
 Increased mand length
 Reduced maxillary length
G. Soft tissues features
ST not involved in aetiology but encourage dentoalveolar compensation.
However there are some features which could be found in class III case
depending in the aetiology of the problem:
1. Orbital rim hypoplasia
2. Increase scleral show
3. Check bone flattening
Mohammed Almuzian, University of Glasgow, 2013 10
4. Malar hypoplasia in midface deficiency
5. Paranasal hallowing
6. Obtuse NLA
7. Reduced incisor show at smile
8. Increase buccalcorridor dark space
9. Upper lip looks thin with reduced vermilion bordershow while lower lip
may be full and pendulous
10. Obtuse LMA
11. Prominent chin
12. Concave or straight profile with anterior divergence.
13. Increased throat length
H. Dental features
1. Class III incisor relationship
2. Mostly CI III molar relationship could be I or even II. The same applied for
canine relationship.
3. Tendency to or full reverse OJ,
4. Reduced OB, AOB may exist
5. Max probably crowded, mandible unlikely to be so but usually spaced.
6. Incisors compensate for Skeletal base, i.e. Proclined maxillary, retroclined
mandibular incisors
Mohammed Almuzian, University of Glasgow, 2013 11
7. Transverse discrepancyexpressed in a form of tendency to posterior cross
bite. It could be unilateral with or without displacement or could be bilateral
mainly without displacement and to lesser extent with displacement
I. Displacements
The displacement could be in an anterior or lateral direction or combination.
It is due to:
 Unsatisfactory edge-to-edge incisor
 Unsatisfactory transverse buccalsegment relationship
J. Facialgrowth
 Tends to be unfavourable i.e. backwards growth rotation.
NB: Bacceti 2007, found that the pubertal peak of mandibular growth in AP and
vertical direction occurred between stages CS3 and CS4 in (corresponding with
the eruption of canines and premolars) and CS4-CS6 late developmental stages
(corresponding with the complete eruption of second and third molars) but 2 time
more in male than female.
IOTN and class III
A reverse overjet
 It is recorded when ALL four incisors are in lingual occlusion.
 If the reverse overjet is greater than 1 mm it is important to investigate whether
the individual has masticatory or speech (M&S) difficulties.
Mohammed Almuzian, University of Glasgow, 2013 12
 There are several methods of investigation but a simple approachis to ask the
individual to count from 60-70 noting any difficulty in pronunciation. In addition,
any signs and symptoms of mandibular dysfunction should be checked.
Crossbite (2.c, 3.c, 4.c)
 An anterior crossbite is when 1, 2 or 3 incisors (but not all of them) are in
lingual occlusion.
 A posteriorcrossbite is recorded when the posterior tooth or teeth are cusp to
cusp or in full crossbitein a buccal or lingual perspective.
 The grade recorded depends on the severity of discrepancybetween retruded
contact position (RCP) and intercuspal position (IP) (Table 3.4).
 The greater the discrepancy between RCP an IP, the higher the grade
Growth status assessmentfor class III patients
Mandibular skeletal maturity can be assessed by means of a series of biologic
indicators:
Mohammed Almuzian, University of Glasgow, 2013 13
1. History (is the patient changing shoes)
2. Growth chart like an increase in bodyheight (Nanda, 1955; Hunter, 1966)
3. Biological parameters like:
 Skeletal maturation of the hand and wrist (Bjork, 1967) or cervical vertebral
maturation (CVM) method. Franchi 2000, Beccteti 2002 & 2005 (please
read the summary about ‘’TheCervical Vertebral Maturation’’)
 Dental development and eruption (Bjork, 1967)
 Chronological age
 Secondarysexual features like Menarche, breast, and voice changes (Tanner
1962)
Monitoring the growthof mandible
1. Serial Clinical measurements like OJ
2. Serial Study models
3. Serial Photograph or 3D stereo photogrammetry
4. Serial Ceph (not justified)
5. Growth Treatment ResponseVector (GTRV) analysis
 Ngan (2005) has described this as a method of determining whether a class 3
malocclusion can be treated by camouflage or if surgical treatment will be
required at a later date.
 It is calculated from two serial cephalometric radiographs at least one year apart.
Mohammed Almuzian, University of Glasgow, 2013 14
 The lines AO and BO are constructed in the same way as for the Wits analysis on
the first radiograph;
 The first radiograph is then superimposed on the second using the stable
structures of the cranial base.
 New AO and BO are then constructed using the occlusal plane of the first
radiograph.
 Horizontal growth change of maxilla is second AO-first AO
 Horizontal growth change of mandible is second BO-first BO
 The GTRVis then given by the following formula:
 GTRV = horizontal growth change of maxilla / horizontal growth change of
mandible
 The normal GTRV of patients is 0.77 – ie: normally, mandibular growth usually
exceeds maxillary growth by 23% between the ages of 8 and 16 years.
Differentiation betweenmandibular prognathsim & maxillary deficiency
Maxillary deficiency Mandibular
prognathism
Frontal Tendency to show sclera Normal show of sclera
Sallow paranasal form Normal paranasal
form
Narrow alar base width Normal alar base
Mohammed Almuzian, University of Glasgow, 2013 15
width
Tendency of upper lip to be
thin
Normal upper lip
Normal chin projection Prominent chin
Normal to decreased lower
facial height (LFH)
Normal, increased or
decreased lower facial
height (LFH)
Profile Nasolabial line-Subnasale:
subnasale-tip of nose ,usually
not 1:1 ratio
Normal
Nasal tip down Normal
Obtuse nasolabial angle Normal nasolabial
angle
Smiling
assessment
Less incisor visible Good
Cephalometric
assessment
Normal to decreased total facial
height
Increased total facial
height
Short Pty-ANS normal
Facial concave Anterior divergent
Normal ramus width Narrow
Mohammed Almuzian, University of Glasgow, 2013 16
Gonial angle normal obtuse
Occlusal
Assessment
Tendency toward crowding and
missing teeth in the upper
Spacing in lower arch
Transverse deficiencies
noticeable in maxillary arch
Normal
Treatment options for class III malocclusion
McIntyre 2004
1. Accept
2. Interceptive treatment
3. Growth modification
4. Orthodontic camouflage
5. Orthodontic decompensation and orthognathic surgery
6. Compromised orthodontic treatment
Factors influencing treatment options in Class III
1. Patient concern(dental or facial concern)
2. Patient age
3. Growth
4. Medical condition
Mohammed Almuzian, University of Glasgow, 2013 17
5. Patient compliance
6. Family history of class III
7. Severity of skeletal problem in AP, V & T direction
8. Clinical condition of the teeth and oral tissues.
9. Amount of the OJ &OB
10. Degree of crowding
11. Degree of compensation
12. Presence of displacement
Summary about treatment strategies according to dental age
a. In primary dentition
There is no evidence to suggest that orthodontic intervention during the primary
dentition avoids, or reduces, the complexity of later orthodontic treatment.
b. In early mixed dentition
1. Incisor crossbites due to retained primary incisors: Treatment extract
retained primary teeth
2. Premature contact and mandibular displacement or incisors erupted in cross
bite relationship, then
 Extract or grind cusp tips (usually primary canines)
 Posterior onlay to overcome the posterior crossbitethat caused
displacement.
Mohammed Almuzian, University of Glasgow, 2013 18
 Procline maxillary permanent incisor(s) using an upper removable appliance
(URA) or a fixed appliance (4 x 2 appliance which is well tolerated less
dependent on compliance (Sandler, 2001) Offer three-dimensional control
 Anterior cross elastics, Reynolds method 1978
 Expand by URA or Q helix…..
c. Mid-Late mixed dentition
 Class III incisors with deep overbite and mild/moderate skeletal Class III:
Protraction headgear and rapid maxillary expansion
 Proclined lower incisors: URA incorporating inverted labial bow or URA to
procline ULS.
d. Early permanent dentition
1. Mild/moderate skeletal discrepancy
 with no concern about facial appearance or growth , Procline maxillary
permanent incisors using URA/fixed appliance or Camouflage skeletal pattern
using fixed appliances with or without extraction.
 With concern about facial appearance or growth
A. Postponetreatment decision until skeletal growth completed.
B. sometime, Align maxillary arch with fixed appliance and relieve crowding,
accepting Class III incisor relationship will require orthognathic surgery in
adulthood
2. Severe skeletal discrepancy or a concern about facial appearance
Mohammed Almuzian, University of Glasgow, 2013 19
 Accept malocclusion will require combined orthodontic
treatment/orthognathic surgery in adulthood
 Align maxillary arch with fixed appliance and relieve crowding, accepting
Class III incisor relationship will require orthognathic surgery in adulthood
e. Adult treatment
1. Mild/moderate skeletal discrepancy
A. no concern about facial appearance
 Procline maxillary permanent incisors using URA/fixed appliance
 Camouflage skeletal pattern using fixed appliances
B. Mild/moderate skeletal discrepancy –concernabout facial appearance
 Compromised treatment by aligning the UA with or without extraction and if
possible align lower arch on non-extraction base to keep the cop of
decompensation if the Combined orthodontic treatment/orthognathic surgery
decided later
2. Severe skeletal discrepancy with no concern about facial appearance
 Compromised treatment by aligning the UA with or without extraction and if
possible align lower arch on non-extraction base to keep the cop of
decompensation if the Combined orthodontic treatment/orthognathic surgery
decided later
3. Severe skeletal discrepancy with a concern about facial appearance
 Combined orthodontic treatment/orthognathic surgery
Mohammed Almuzian, University of Glasgow, 2013 20
Reasonsfor early treatment of class 3 malocclusions
Hägg et al (2004) and Ngan (2005) cite the reasons for early treatment as:
a. To eliminate CR-CO discrepancies which may cause
 periodontal damage
 occlusal wear
 TMJ problems
b. To provide a more favourable environment for growth and
development of the maxilla and mandible with a reduction in dental
compensation because remodelling may occurin the joint as the postured position
which will act as functional appliance and making correction of the crossbite
more difficult at a later date
c. To provide spacefor the eruption of the buccalsegments as a result of
proclination of the upper incisor so the canines and premolars can be guided into
a class 1 relationship
d. Psychological benefits resulting from improved dental and facial
appearance
Orthopaedic treatment option
Effectof orthopaedic appliance in class III maloculsion
Dermaut and Aelbers (1996) have reviewed the possible effects of orthopaedic
treatment in class 3 malocclusions.
1. 50% of the studies showed stimulation of maxillary growth
Mohammed Almuzian, University of Glasgow, 2013 21
2. 90% showed an inhibition of mandibular projection
 In general orthopaedic appliances are more effective if cl3 is due to maxilla
retrusion than mand prognathism.
 However, most of the effects are dentoalveolar in nature with maxillary incisor
proclination and mandibular retroclination.
Predictive factors for orthopaedic treatment
1. Patient’s factors
 good co-operation
 No familial prognathism
2. Growth
 Young growing patient
3. Soft tissue
 Acceptable facial aesthetics
4. Skeletal
 Mild skeletal discrepancy (ANB < -20 )
 Normal MMPA
 No asymmetries (Symmetrical condylar growth)
5. Dental
 -2mm reverse OJ or edge to edge relationship
Mohammed Almuzian, University of Glasgow, 2013 22
 Minimal dental compensation
6. Displacement
 Functional shift
Types of orthopaedic treatment in class III malocclusion
1. ProtractionHG
Definition
Means of applying anterior directed forces to teeth and/or skeletal structures from
an extra-oral source
History
 The technique of maxillary protraction is based on work by Nanda (1978), with
rhesus monkeys in which he showed that a force of approximately 500g could
produceanterior displacement of the maxilla
 It is appropriate to refer to this type of treatment as facemask therapy.
Indications
A. Treatment of maxillary retrusion. An ideal case would be;
1. Patient’s factors
 good co-operation
 No familial prognathism
Mohammed Almuzian, University of Glasgow, 2013 23
7. Growth
 Young growing patient
8. Soft tissue
 Acceptable facial aesthetics
9. Skeletal
 Mild skeletal discrepancy (ANB < -20 )
 Normal MMPA
 No asymmetries (Symmetrical condylar growth)
10. Dental
 -2mm reverse OJ or edge to edge relationship
 Retroclined ULS
 Proclined LLS
11. Displacement
 Functional shift
B. Reinforcement of anterior anchorage and dental protraction allowing closure of
spacefrom behind in patients suffering from hypodontia
C. Stabilization following maxillary osteotomy/distraction osteogenisis
D. Rotate arch segments in cleft palate patients
E. Remove hyper-anterior contact in TMJ internal derangement cases,
Mohammed Almuzian, University of Glasgow, 2013 24
Timing
1. Dental age: McNamara (1987) suggested that the optimal time for treatment is in
the early late mixed dentition, coincident with the eruption of the upper
permanent incisors.
2. Skeletal age: Baccetti et al (1998) showed that the early treatment group CVM2
showed effective forward displacement of the maxillary structures whereas the
late treatment group CVM3 showed no change compared with controls
3. Chronological age: Other investigators have suggested that for optimal
orthopaedic effects, treatment should be initiated before the patient is 9 years old
(Proffit, 2000). Mandal 2010, 2012 used it at age of 8.5-10 year.
Kim et al., 1999, meta-analysis of effectiveness of protraction HG concluded it
was less effective on patients >10yrs
Effects
1. Correction of a centric occlusion-centric relation discrepancy. This correction
happens relatively rapidly in patients with an edge to edge relationship and
associated displacement
2. Maxillary skeletal protraction, with up to 3mm of forward movement of the
maxilla possible , Mandal 2010 and 2012, showed that these effect are stable after
3 years follow-up
3. Proclination and forward movement of the maxillary dentition
4. Lingual tipping of the lower incisors
5. Redirection of mandibular growth in a downward and backward direction,
resulting in an increase in lower anterior facial height
Mohammed Almuzian, University of Glasgow, 2013 25
Protractionface mask system
A. Types Extraoral part
1. ProtractionHeadgear(Hickham)
2. FacialMask (Delaire)
3. Suborbital ProtractionAppliance (Grummons)
 Advantages: frame more rigid, no force on TMJ, no LLS
retroclination, easy to adjust and wear during sleep
 Disadvantages: not esthetic due to midfacial support
4. 4. Nola protraction appliance
5. Petit style face mask
The Petit style with a single central vertical bar is also well
tolerated and recent price changes have made it
economically much more attractive.
B. Intraoral part:
Mohammed Almuzian, University of Glasgow, 2013 26
1. In order to maximize the amount of skeletal change in young children, a
removable full coverage acrylic splint is used with a protraction headgear (Proffit
1986).
2. McNamara (1987) has described the use of a Biocryl and wire splint that is
bonded in the mouth. The splint material should be at least 3 mm thick with a
0.045" stainless steel wire framework. The two halves of the splint are joined by
an expansion screw. Traction hooks to receive the elastics from the headgear are
placed in the first premolar region.
3. RME with hook can be used
4. Fixed appliance
5. Some recommend using an intraoral bone plate to supportthe PHG force.
Systematic review to compare the dentally anchored face mask with skeletally
anchored one by Major (2012) in Canada, he found Approximately 3 mm of
horizontal A-point movement is predictably attainable with the skeletal one in
comparison to dental one..
C. Rapid maxillary expansion
Advantages
(Haas 1973).
1. Sutural loosening
2. Correct transverse discrepancy that commonly associated with class III
malocclusion
3. Displace the maxillary complex anteriorly. This is due to butterfly effect of
expansion at the Midpalatal suture and becauseof the anterior sloping of the
facial sutures
Mohammed Almuzian, University of Glasgow, 2013 27
Evidences
1. Many clinicians use protraction with a facemask following or simultaneously
with palatal expansion, because some evidence suggests that the expansion makes
antero-posterior skeletal change more likely. Kim et al (1999)
2. There is other evidence that the expansion is optional and should be dictated by
the maxillary arch width related to the lower arch width, Vaughan 2001 and 2005.
D. Techniques
 First step is to fabricate and bond/cement the rapid maxillary expansion appliance
 Appliance is activated once per day until the desired increase in maxillary width
has been obtained.
 If patients do not need an increase in maxillary width, the appliance is still
activated for 7-10 days to disrupt the maxillary sutural system and promote
maxillary protraction (Haas, 1965)
 After the patient activated the maxillary appliance for 7-10 days protraction
headgear is fitted.
E. Forcelevel
1. Moving maxillary anterior teeth forward: 400g per side, 12-14h/day
2. Maxillary protraction : 800g per side, 14h/day
3. Overcorrect to compensate for mandibular growth
4. Active treatment should be limited to 9-12 months because of the risk of
decalcification of the dentition
F. Forcedirection:
1. To avoid bite opening, place protraction elastics near maxillary bicuspids,
2. Forcevector should be 15-30 degree below the horizontal
Mohammed Almuzian, University of Glasgow, 2013 28
3. To avoid irritation to the lip, use crossed elastic,
4. Pay special attention to airway and tongue posture
5. Ishii et al (1987) describe the effects of providing the protraction force from the
first molars or the premolar region. Protraction from the first molars results in
more anterior movement and a forward and upward rotation of the maxilla;
protraction from the premolars results in less forward movement but fewer
tendencies to upward and forward rotation.
G. Transitional period
After treatment objectives have been achieved, the patient can be retained with a
number of appliances:
 The facemask,
 FR-3 appliance
 Acrylic maxillary retainer with reverse lower labial bow
 Chin cup (seldom used).
H. Postprotraction treatment consideration
1. As mandibular growth exceeds maxillary growth during adolescence, early Class
III correction may be lost during the teenage period. The patients and parents
should again be warned of the possibility of orthognathic treatment if growth is
unfavourable
2. Upper labial root torque during fixed appliance stage: Most class 3 patients
demonstrate considerable proclination of the upper labial segment at the end of
treatment. Catania et al (1990) recommend in his case report to use inverted U
incisor bracket to counteract the effect of proclination.
Mohammed Almuzian, University of Glasgow, 2013 29
Evidence based short term effectivenessofPH
Mandall, 2010 (similar to study of Ngan 1998)
 Early Class III orthopaedic treatment with protraction face mask in patients
less than 10 years of age is skeletally and dentally effective in the short term 15
months. (After 15 months of treatment, children undergoing early facemask
therapy had 1.3 degrees more forward movement of SNA, almost 2degrees less
forward movement of SNB and an overall ANB improvement of around 2.6
degrees when compared to the controlgroup. In addition, the overjet improved by
more than 4 mm and the relative PAR scoreby more than 40% in the facemask
compared to the control group. Thus, early class III protraction facemask
treatment in patients under 10 years of age would seem to be skeletally and
dentally effective in the short-term)
 70% of patients had successfultreatment, defined as achieving a positive
overjet.
 Early treatment does not seem to confer a clinically significant psychosocial
benefit.
 No TMJ problem
Evidence based long term effectivenessofPH
 Mandal 2012:Early Class III orthopaedic treatment with protraction face
mask in patients less than 10 years of age is skeletally and dentally effective after
3 years of treatment.
 Masucci 2011: RME/FM therapy led to successfuloutcomes in about 73%
of the patients. Significantly improved sagittal dentoskeletal relationships. These
Mohammed Almuzian, University of Glasgow, 2013 30
favourable changes were mainly due to significant improvements in the sagittal
position of the mandible, but the maxillary changes reverted completely in the
long term. This treatment not induces a tendency of bite opening or increased
vertical relationship.
 A Cochrane review by Watkinson in 2013. This review looked at the use of
four different types of orthodontic treatment for correcting prominent lower front
teeth in children.-Facemask-Chin cup-Mandibular -Tandem traction bow
appliance. This review found some evidence that the use of a facemask appliance
can help to correctprominent lower front teeth on a short-term basis. There was
no evidence available to show whether or not these short-term changes will still
be maintained until the child is fully grown. There was not enough evidence to
supportany other types of treatment for prominent lower front teeth.
2. Alternate Rapid Maxillary Expansion and Constriction(Alt-
RAMEC)
 Original technique:
 A protocolof maxillary protraction developed by Liou and Tsai in 2005.
 It includes 3 components:a 2-hinged rapid maxillary expander, repetitive
weekly protocolof Alternate Rapid Maxillary Expansion and Constriction
(Alt-RAMEC), and intraoral maxillary protraction springs.
 The innovative part of this technique is the sutural loosening accomplished
by alternating expansion with constriction for 8 weeks.
Mohammed Almuzian, University of Glasgow, 2013 31
 This backand- forth motion can mobilize the maxilla and protract the
maxilla for longer distances. Liou 2005
 The Alt-RAMEC protocolthe maxilla is expanded for 7 consecutive days
and constricted for 7 consecutive days for 9 weeks. After the Alt-RAMEC
technique, the maxilla is protracted with protraction springs for 3 months.
The technique has been modified to use a standard Hyrax rapid maxillary
expansion appliance and fixed orthodontic appliances in the lower arch, Class III
Mohammed Almuzian, University of Glasgow, 2013 32
elastics and reverse-pull headgear or facemask (Yen 2011).
The Clinical Protocol for Maxillary Protractionina Typical Adolescent
Patient With Cleft Lip and Palate
● At age 13, the patient chooses surgery or maxillary protraction.
Maxillary expansion and protraction was performed before dental alignment with
an archwire because additional space was created with arch expansion. If
maxillary dental crowding was present, extractions were deferred until after
expansion and protraction. The exceptionsto this rule were the patients who had
molars and premolars tilting in oppositedirectionswhich would prevent parallel
draw of bands. These patients received limited orthodontics with sectional wires
to improve the insertion and draw of a rapid palatal expander (RPE).
● Pretreatment records. Check for parallel path of insertion of RPE along anchor
teeth. Prior alignment is needed if teeth are tilted in oppositedirections.
● Banding of the lower first and second molars, bonded orthodontic brackets for
the lower arch premolars and anterior teeth. Initiate leveling of mandibular
dentition. Stabilize lower dentition in a stainless steel rectangular archwire;
● Banding maxillary molars and premolar (or canines) for a Hyrax rapid palatal
expander placed high in vault of palate.
● Delivery of Hyrax expander. Demonstration of screw turns needed to expand
and constrict the Hyrax expander. Sutural loosening is initiated by activating the
appliance 2 turns in the morning and 2 turns in the evening. The expansion rate is
1 mm/d. The screw turns follow the same direction for 1 week.
Mohammed Almuzian, University of Glasgow, 2013 33
● At the end of the week, the patient returns to the clinic to demonstrate ability to
insert the swivel key into the screw of the Hyrax expander. The swivel key is
suspended in the RPE before activation to ensure that the key is fully inserted.
The reverse direction is taught so that patient so that he/she is proficient in both
directions with the swivel key.
● Expansion and constriction is alternated each week. Recall after 4 weeks.
● After 8 weeks of alternating expansion with constriction, the facemask and
Class III elastics are given to the patient to start protraction. The patients are
instructed to wear the facemask at night to “pull” the maxilla forward and wear
the
Class III elastics during the day to “hold” the results obtained by the facemask.
Expansion and constriction are continued during protraction. The facemask bar
for protraction elastics is placed at the level of the lower lip to provide
a slight downward direction of pull from the premolar bands in the Hyrax
expander. The facemask is used with elastics to the premolar bands during the
evening. Heavy force Class III elastics are placed from hooks anterior to the
mandibular canine to the maxillary first molar bands of the Hyrax expander 24
hours/day with intermittent changes before and after meals. The elastics are
stretched to their elastic limit to maximize force.
● After 2 weeks, the patient returns to demonstrate ability to use facemask and
intraoral elastics. Some correction, such as edge-to-edge occlusion should have
occurred by this time. The elastics are changed to heavier and shorter elastics as
the distance between RPE and headgear is shorter.
Mohammed Almuzian, University of Glasgow, 2013 34
● Continue the facemask and Class III elastics until the underbite is over
corrected into a Class II malocclusion by at least
3 mm. Maintain the correction with 24-hour Class III elastics.
● After 4 months, remove RPE and replace with maxillary brackets and bands for
orthodontic alignment.
● Class III elastics are used for 18 months during the arch alignment, finishing
and retention stages of treatment.
Masucci1 2014, (retrospective control trial)) (young children aged 6.1 yers) Both
the Alt-RAMEC/FM and the RME/FM protocols showed significantly favorable
effects leading to correction of the Class III malocclusion. The Alt-RAMEC/FM
protocolproduced a more effective advancement of the maxilla (SNA +1.2°) and
greater intermaxillary changes (ANB +1.7°) vs. the RME/FM protocol. No
significant differences were recorded as for mandibular skeletal changes and
vertical skeletal relationships.
Effectiveness of maxillary protraction using facemask with or without maxillary
expansion: a systematic review and meta-analysis, Foersch, 2015. The statistical
analysis of treatment changes advocates a positive influence on sagittal maxillary
development, which is not primarily influenced by transverse expansion. Dental
side effects are more distinct when no expansion was carried out. Forthe concept
Mohammed Almuzian, University of Glasgow, 2013 35
of alternating activation/deactivation of the expansion appliance (alt-RAMEC),
two articles of high methodological scoring were identified. They indicate an
enhancement of face mask treatment.The findings are consistent with results of
previous literature studies regarding the efficiency of class III face mask
treatment. A further need for more randomized controlled studies was identified
especially with regard to the new conceptof alternating maxillary expansion and
compression, which showed a positive influence on the maxillary protraction
based on two studies.
Clinical relevance
Class III therapy using extraoral face mask anchorage is effective for maxillary
protraction. The recently discussed new protocols potentially improve this
treatment.
3. Tandem traction bow appliance:
attachments are fixed to the top and bottom teeth. In the top attachment there is a
hook on each side. A metal bar is placed in the lower attachment, which sits in
front of the lower teeth. An elastic band can then be placed on each side to pull
the top jaw forward and bottom jaw backwards, to correctthe prominent lower
teeth
Mohammed Almuzian, University of Glasgow, 2013 36
4. Chin caps
 The idea of this appliance is that because the condyle is a growth site, the
growth impeded by extra-oral force (Graber, 1977).
 Despite success in animal experiments, most human studies have found little
difference in mandibular dimensions between treated and untreated subjects
(Sugawara et al, 1990).
 Chincup appliances greatly improve the skeletal profile in the short term
such changes are however rarely maintained during the pubertal growth spurt
 Force500g per side 12-14 h/day for 4-5 years. Once the anterior crossbite
was corrected, the patient was instructed to wear the chin cup at least 10 hours per
day until slight Class II canine and molar relationships were established.
 The bestage is before canine and premolar erupt (CS2-CS3maturity) this is
the first growth spurt of mandible, the second one when 7 and 8 erupt CS4-CS6
(Bacceti, 2005).
 Types: occipital pull, used for patients with mandibular prognathsim or
vertical pull, used for patients with increased anterior face height
Bestpatient for Chin cup therapy
Ko et al (2004)
1. Mild Skeletal III, ability to achieve edge to edge incisors
2. Short vertical facial height (.Chincup cause clockwise rotation of the
mandible.
3. Proclined or upright LLS (Chincup cause lingual tipping of the lower
incisors (Thilander 1963)
4. Absence of severe facial and dental asymmetry
Mohammed Almuzian, University of Glasgow, 2013 37
The effects ofchincup therapy
(Thilander 1963)
 Retardation of mandibular growth. Effective at reducing mandibular
prognathism before puberty but this is then lost with continual growth, Sugawara
et al., 1990
 Remodelling of the condyle and glenoid fossa
 Backward rotation of the mandible
 Closure of the gonial angle
 Result in lingual tipping of LLS,
5. Reverse chin cup therapy
 Developed in Germany in 2012 by Rahman 2012 show similar result when
the reverse chin cup therapy compared to face mask therapy in RCT involving 42
samples at age of 8-9 years.
 Reverse chin cup therapy is able to produceforward movement of the
maxilla in the growing child associated with lingual tipping of the lower incisors
and labial tipping of the uppers.
Mohammed Almuzian, University of Glasgow, 2013 38
 The point of application of protraction elastics from the upper removable
appliances was similar for both groups. All patients received the same protraction
force of 500 g per side with a 30 degree downwards pull.
 The proposedadvantages of the new reverse chin cup design were that it
was smaller and less bulky than other protraction appliances, therefore
encouraging children to wear it.
6. Bone anchored orthopaedic appliance (Bollard miniplates, PFH
supported with miniplates)
 Plate comes in different size and form. It should
be adapted to the bone surface and fixed with 2.5mm
width and 5mm length screw.
 Heavy Class 3 elastic used
 Age of 9-13
 Forceabout 150gm 24h per day. Loading start 3 weeks after plate insertion.
 The major problem with this technique is the low rigidity of bone for young
patient which affect stability of bone plate and the presence of teeth follicle which
might cause problem with implant insertion. Also plate removal is problematic
bec it needs surgery and sometime the bone grow over the screw.
 Success rate 92% with 3mm improvement of maxilla position and zygoma.
(Nguyen 2011) (De Clerck 2011)
 This approachhas two advantages:
Mohammed Almuzian, University of Glasgow, 2013 39
1. it is clearly more effective than a facemask to a maxillary splint and also
appears to producemore skeletal change than has been reported with
facemasks to anterior miniplates
2. wearing an Extraoral appliance is not necessary and nearly full-time
application of the force can be obtained.
7. Shapiro and Kokich 1984 usedthe same idea by inducing artificial
ankylosis and use the ankylosedteeth as anchor.
8. Functional appliances
Reverse twin block
a. The design included
 Cantilever springs behind the upper incisors,
 A midline expansion screw,
 A lower labial bow
 Intersecting blocks at 70 degrees with a vertical height of 7 mm.
 Block on U4s,5s and L5s,6s
b. The patient was instructed to wear the appliance on a full-time basis initially,
activating the midline expansion screw twice a week.
c. Effects:
 There is no sustained effect on growth of either the maxilla or mandible.
Reverse TB for mandibular prognatisim (Ucem 2004 claim that it producedental
effect only) Although there is a reduction in SNB and an increase in ANB due to
Mohammed Almuzian, University of Glasgow, 2013 40
the backwards and downwards rotation of the mandible and an increase in lower
face height. Therefore, this type of treatment is inappropriate for high angle cases
with an already increased FMPA.
 Seehra 2012, compare the effectiveness of Reverse Twin-Block therapy
(RTB) and protraction face mask treatment (PFM) with respect to an untreated
control in the correction of developing Class III malocclusion. Both appliances
are capable of correction of Class III dental relationships; however, the relative
skeletal and dental contributions differ. Skeletal effects, chiefly anterior maxillary
translation, predominated with PFM therapy. The RTB appliance induced Class
III correction,
 Primarily as a result of dentoalveolar effects and by clockwise rotation of the
mandible.
The FR 3
 They are designed to rotate the mandible downward and backward, and to
guide the eruption of the teeth so that the upper posterior teeth erupt down and
forward whilst eruption of the lower teeth is restrained. This rotates the occlusal
plane in the direction that favours correction of a class III molar relationship.
 These appliances also tip the mandibular incisors lingually and the maxillary
incisors labially, introducing an element of dental camouflage for the skeletal
discrepancy.
 In theory, the lip pads stretch the periosteum in a way that stimulates
forward growth of the maxilla. .
Mohammed Almuzian, University of Glasgow, 2013 41
Camouflage (dental compensationfor mild cases)
Indications
1. Growth
 Patient pastpeak growth
 Non-progressive worsening of the Class III.
2. Skeletal
 Class I or mild class III skeletal base relationship;
 Average or reduced lower face height;
3. Dental
 Average or increased overbite;
 Minimal reverse OJ or edge-edge relationship
 Proclined lower incisors;
 Upright or retroclined upper incisors;
 Molar relationship less than half unit Cl Ill
4. Soft tissues features
1. Patient not concern about the profile
2. Favourable softtissue features
5. Displacement
Mohammed Almuzian, University of Glasgow, 2013 42
 Anterior displacement on closing from RCP into ICP.
Techniques of camoflagable treatments
1. Non extraction
 Expansion in upper arch to relieve crowding, eliminate crossbites and
mandibular displacements
 Procline upper incisors, retrocline lower incisors (it is unwise to procline the
upper incisors beyond 120 degrees to the maxillary plane or retrocline the lower
incisors beyond 80 degrees to the mandibular plane.)
2. Extraction:
Aims of extraction
 To relieve crowding or ML,
 Correct incisor inclination
 Correction of class III
 To achieving a positive overjet
 To achieving a positive overbite
 To constrict the lower arch in order to correct any transverse problems
Options of extraction:
 Extraction upper 5`s to maintain U lip support+ lower 4`s to allow LLS
retroclination.
Mohammed Almuzian, University of Glasgow, 2013 43
 Extraction of 4x4.
 Extraction of a single lower incisor: If the upper arch is well-aligned but
spaceis required to align and retrocline the lower incisors, extraction of a single
lower incisor can be an option (Zachrisson 1999) but it may leave some black
triangle and gingival recession. This decision depend on the presence of (large IC
distance, minor crowding, TSD in LLS, square shape L incisors not triangular). A
better approachto camouflage in patients of European descentwith a moderately
severe Class III problem is extraction of one lower incisor, which prevents major
retraction of the lower teeth, while the maxillary incisors are moved facially with
some tipping allowed. The combination of upright mandibular incisors and
proclined maxillary incisors often leads to good dental occlusion rather than the
expected tooth-size problem, but a wax setup always should be done when one
lower incisor extraction is considered to verify the probably occlusal outcome.
 Proffit 2013, For Asian (or rarely, other) Class III patients with major
protrusion of the lower incisors, using skeletal anchorage to move the whole
lower arch posteriorly can be quite helpful in correcting the problem. Extraction
of third molars usually is needed in order to move the mandibular dental arch
back. If second molars are extracted to facilitate distal movement, third molars
may erupt as satisfactory replacements, but this is not as likely as in the maxillary
arch and therefore is not recommended as a routine procedure.
Bracket setup
 To get further proclination of ULS, use MBT in the ULS
 Lingual crown torque on LLS
Mohammed Almuzian, University of Glasgow, 2013 44
 Contra-lateral canine brackets (to avoid LLS proclination)
Mechanics
 Lacebacks in LA (to avoid LLS proclination)
 Cinch back in LA (to avoid LLS proclination)
 Banding 7`s to increase posterior anchorage to retract lower dentition
 Closing spaceon a round wire in the lower arch will facilitate
retroclination of the lower incisors.
 CIII elastics (better to use short class III elastic to avoid posterior teeth
overeruption)
 Avoid distal headgear forces on maxilla in C3 patients
NB: do not extract in lower arch if surgery is anticipated
Transverse problem can be addresses by:
1. URA
2. Q helix
3. RME
4. If more than 8mm, Surgically assisted RME
5. Constriction of the LA
6. AW expansion of the UA
7. Auxillary AW in the UA
Mohammed Almuzian, University of Glasgow, 2013 45
Orthognathic surgery options
The types of surgery most frequently used are the following.
1. Sagittal split ramus osteotomy(SSRO)or bilateral sagittal split osteotomy
(BSSO) to set the mandible backward
2. Intraoral vertical ramus osteotomy(IVRO) or vertical subsigmoid osteotomy
(VSSO) or vertical or oblique subcondylar osteotomy(VSO) is different names
for the same technique using an intraoral approach. This type of surgery is used to
reduce the size of the mandible (Cheung 2002). Contraindicated in predisposed
toward developing obstructive sleep apnea syndrome (OSAS) (Turnbull 2000;
Chen 2005).
3. Mandibular step osteotomy(MSO). This is a surgical technique on the
mandible that is performed in the anterior region of the mental foramen. It is
indicated for correcting the size of the mandible by using the spaceresulting from
the extraction of a posterior tooth or for closing spaces caused by lost posterior
teeth. MSO enables vertical and transversal modifications to the dental arches:
closure of an anterior open bite and correction of the reverse curve of Spee. This
type of osteotomy presents stepwise sectioning, which allows the bone segments
to be brought together as much as possible, thereby ensuring their stability. The
fixation is accomplished with a miniplates on each side (Cheung 2002).
Mohammed Almuzian, University of Glasgow, 2013 46
4. Surgically assisted rapid palatal expansion (SARPE) to correctthe combined
transverse problems
5. Le Fort I (total maxillary osteotomy), the combination of Le FortI and Le
Fort III, or Le Fort II in one operation or different operations.
Sugaya 2012 Cochrane review two randomized controlled trials were included in
this review. There are different types of surgery for this type of malocclusion but
only trials of mandible reduction surgery were identified. One trial compared
intraoral vertical ramus osteotomy(IVRO) with sagittal split ramus osteotomy
(SSRO)and the other trial compared vertical ramus osteotomy(VRO) with and
without osteosynthesis. Neither trial found any difference between the two
treatments. The trials did not provide adequate data for assessing effectiveness of
the techniques described
Complications of the mandibular ramus surgery
1. Fractures of the osteotomised segments,
2. Incomplete sectioning (Van Merkesteyn 1987),
3. Infection, necroses, persistent paresthesia,
4. Reduced mouth opening, nausea, airway disturbance (Yamada 2008),
5. Reduced mandibular movement range (Yazdani 2010).
6. Trauma to the inferior alveolar nerve,
Mohammed Almuzian, University of Glasgow, 2013 47
What Factors needto be takeninto Account When Planning a surgical
treatment for class III cases
1. Planning the type of surgery
The required surgery is planned around the aetiology of the skeletal discrepancy
taking into account facial aesthetics, stability of the result, TMJ and airway, little
morbidity. Allows the decision to make regarding whether the maxilla is to be
advanced or the mandible set back, or a combination of these.
2. The Pre-SurgicalOrthodontics in Class III?
The pre-surgical orthodontics is planned around the surgery required to achieve
optimal aesthetics with the best achievable occlusion. Three important points
need to be considered;
1. Expansion: Assessment of arch co-ordination using the pre-treatment models
in a class I position will identify the extent of any required expansion of the
maxillary arch. If minimal expansion is required, this can be achieved using the
orthodontic archwires during pre-surgical orthodontics.
2. Reverse Target overjet: The planned surgical moves for optimal aesthetics
dictate the reverse overjet required pre-surgically.
3. Inclination of the ULS which is determined by the degree of maxillary
impaction while the inclination of LLS would be determined by the amount of
autorotation.
What Are the Aims of the Pre-SurgicalOrthodontics?
1. Alignment
2. Levelling and alignment of the arches.
Mohammed Almuzian, University of Glasgow, 2013 48
3. Arch co-ordination.
4. Decompensation: In this case, decompensation of the upper and lower
arches was required to producean appropriate reverse overjet pre-surgically and
allow the desired surgical movements to be carried out to promotethe desired
facial change.
5. Maintenance of the centre line with the mid-point of the chin in Lower teeth
and philtrum in the upper teeth.
Borderline Camouflage/ Orthognathic Surgery Patients
The decisionwill depend on
1. Growth where there is any doubtabout further skeletal growth (principally
mandibular), orthodontic camouflage should be deferred, possibly until the
remaining skeletal growth has been expressed. In class III cases with a significant
skeletal component, the mandible will tend to grow more and later than in class I
individuals (Baccetti et al, 2007).
2. Any concerns aboutfacial appearance.
3. Medicaland family history
4. Severity of the underlying skeletal problem
5. Presence or absence of functional displacement
6. Degree dentoalveolar compensation
7. Amount of crowding, OJ, OB
Mohammed Almuzian, University of Glasgow, 2013 49
8. Vertical height
9. Cephalometric Yardsticks
A. Kerr et al 1992 in Glasgow showed that surgery is indicated for patients with
 ANB <-4°
 Maxillary mandibular ratio = 0.84
 Lower incisor inclination (LI/MP <= 83°)
 Soft tissue profile Holdaway angle > = 3.5° (Holdaway angle means soft
tissue nasion-soft tissue pogonion labrale superius)
 Interestingly, vertical dimension had little influence on treatment decision.
B. Stellzig-Eisenhauer et al (2002) surgery indicated when Wits analysis value
of –12.2 ± 4.3 mm or more while camouflage indicated when Wits value is -4.6 ±
1.7 mm or less.
Summary ofthe evidences
 BSI 1982 defined class III incisor relationship as ‘’the lower incisal edge lies
anterior to the cingulum plateau of the upper incisors, British Standards Institute,
1983
 3% UK (Foster & Day, 1974)
 Anterior crossbitein 10% of children (1993 Child Dental Health Survey)
 Lin (2007) divides class 3 malocclusion into three categories
 Guyer, Ellis, Behrents and McNamara (1986) 55% of class 3 malocclusions had
maxillary deficiency as one of the components of the malocclusion. Mandibular
Mohammed Almuzian, University of Glasgow, 2013 50
prognathism in 45% of cases.
 Guyer, Ellis, Behrents and McNamara (1986), 59% of class 3 malocclusions had
reduced or neutral lower facial heights and that 41% had increased lower facial
heights.
 The maxillary skeletal base widths were (statistically) significantly smaller in the
class 3 than in the class 1group. (Chen et al 2008)
 Skeletal asymmetries, particularly in conjunction with mandibular prognathism,
are also relatively common in class III malocclusions (Severt and Proffit, 1997).
 Growth status assessment for class III patients
1. Mandibular skeletal maturity can be assessed by means of a series of biologic
indicators:
2. Increase in bodyheight (Nanda, 1955; Hunter, 1966)
3. Skeletal maturation of the hand and wrist (Bjork, 1967)
4. Dental development and eruption (Bjork, 1967)
5. Menarche, breast, and voice changes (Tanner 1962)
6. Cervical vertebral maturation (CVM) method. Franchi 2000, Beccteti 2002 &
2005 (please read the summary about ‘’TheCervical Vertebral Maturation’’)
 Growth Treatment ResponseVector (GTRV) analysis, Ngan (2005) has described
this as a method of determining whether a class 3 malocclusion can be treated by
camouflage or if surgical treatment will be required at a later date.
 Treatment options for class III malocclusion, McIntyre 2004
 Procline maxillary permanent incisor(s) using an upper removable appliance
(URA) or a fixed appliance (4 x 2 appliance which is well tolerated less
dependent on compliance (Sandler, 2001) Offer three-dimensional control
 Reasons for early treatment of class 3 malocclusions, Hägg et al (2004) and Ngan
Mohammed Almuzian, University of Glasgow, 2013 51
(2005) cite the reasons for early treatment
 The technique of maxillary protraction is based on work by Nanda (1978), with
rhesus monkeys in which he showed that a force of approximately 500g could
produceanterior displacement of the maxilla
 Timing, Dental age:
1. McNamara (1987) suggested that the optimal time for treatment is in the early
late mixed dentition, coincident with the eruption of the upper permanent
incisors.
2. Skeletal age: Baccetti et al (1998) showed that the early treatment group CVM2
showed effective forward displacement of the maxillary structures whereas the
late treatment group CVM3 showed no change compared with controls
3. Chronological age: Other investigators have suggested that for optimal
orthopaedic effects, treatment should be initiated before the patient is 9 years old
( Proffit, 2000).
4. Kim et al., 1999, meta-analysis of effectiveness of protraction HG concluded it
was less effective on patients >10yrs
 Maxillary skeletal protraction, with up to 3mm of forward movement of the
maxilla possible , Mandal 2010 and 2012, showed that these effect are stable after
3 years follow-up
 McNamara (1987) has described the use of a Biocryl and wire splint
 Some recommend using an intraoral bone plate to supportthe PHG force.
Systematic review to compare the dentally anchored face mask with skeletally
anchored one by Major (2012) in Canada, he found Approximately 3 mm of
horizontal A-point movement is predictably attainable with the skeletal one in
comparison to dental one..
Mohammed Almuzian, University of Glasgow, 2013 52
 Many clinicians use protraction with a facemask following or simultaneously
with palatal expansion, because some evidence suggests that the expansion makes
antero-posterior skeletal change more likely. Kim et al (1999)
 There is other evidence that the expansion is optional and should be dictated by
the maxillary arch width related to the lower arch width, Vaughan 2005.
 Ishii et al (1987) describe the effects of providing the protraction force from the
first molars or the premolar region. Protraction from the first molars results in
more anterior movement and a forward and upward rotation of the maxilla;
protraction from the premolars results in less forward movement but less
tendency to upward and forward rotation.
 Chin caps, The idea of this appliance is that because the condyle is a growth site,
the growth impeded by extra-oral force (Graber, 1977).
 Despite success in animal experiments, most human studies have found little
difference in mandibular dimensions between treated and untreated subjects
(Sugawara et al, 1990).
 The effects of chincup therapy , (Thilander 1963)
 Reverse chin cup therapy, Developed in Germany in 2012 by Rahman 2012 show
similar result when the reverse chin cup therapy compared to face mask therapy
in RCT involving 42 samples at age of 8-9 years.
 Bone anchored orthopaedic appliance (Bollard miniplates, PFH supported with
miniplates) , Success rate 92% with 3mm improvement of maxilla position and
zygoma. (Nguyen 2011) (De Clerck 2011)
 Shapiro and Kokich 1984 used the same idea by inducing artificial ankylosis and
use the ankylosed teeth as anchor.
 Reverse twin block, There is no sustained effect on growth of either the maxilla
Mohammed Almuzian, University of Glasgow, 2013 53
or mandible. Reverse TB for mandibular prognatisim (Ucem 2004 claim that it
producedental effect only)
 Extraction of a single lower incisor: If the upper arch is well-aligned but spaceis
required to align and retrocline the lower incisors, extraction of a single lower
incisor can be an option (Zachrisson 1999) but it may leave some black triangle
and gingival recession. This decision depend on the presence of (large IC
distance, minor crowding, TSD in LLS, square shape L incisors not triangular).
 Sugaya 2012 Cochrane review Two randomized controlled trials were included in
this review. There are different types of surgery for this type of malocclusion but
only trials of mandible reduction surgery were identified. One trial compared
intraoral vertical ramus osteotomy(IVRO) with sagittal split ramus osteotomy
(SSRO)and the other trial compared vertical ramus osteotomy(VRO) with and
without osteosynthesis. Neither trial found any difference between the two
treatments. The trials did not provide adequate data for assessing effectiveness of
the techniques described
 Cephalometric Yardsticks, Kerr et al 1992 , Stellzig-Eisenhauer et al (2002)

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Class iii malocclusion / for orthodontists by Almuzian

  • 1. UNIVERSITY OF GLASGOW Class III Malocclusion Personal notes Mohammed Almuzian 2/20/2013 ……………………………………….
  • 2. Mohammed Almuzian, University of Glasgow, 2013 1 Table of Contents Definition......................................................................................................... 5 Incidence ......................................................................................................... 5 Classification ................................................................................................... 6 Aetiology......................................................................................................... 6 Features of Class III.......................................................................................... 7 A. Skeletal features ........................................................................................ 7 B. Soft tissues features ................................................................................... 8 C. Dental features .......................................................................................... 8 D. Displacements........................................................................................... 8 E. Facial growth ............................................................................................ 8 IOTN and class III.......................................................................................... 11 Crossbite (2.c, 3.c, 4.c) ................................................................................... 12 Growth status assessment for class III patients ................................................. 12 Monitoring the growth of mandible ................................................................. 13 Differentiation between mandibular prognathism & maxillary deficiency ......... 14 Treatment options for class III malocclusion.................................................... 16
  • 3. Mohammed Almuzian, University of Glasgow, 2013 2 Factors influencing treatment options .............................................................. 16 Summary about treatment strategies according to dental age ............................ 17 Reasons for early treatment of class 3 malocclusions ....................................... 20 Orthopaedic treatment option.......................................................................... 20 Effect of orthopaedic appliance in class III maloculsion ................................... 20 Positive factors for orthopaedic treatment ........................................................ 21 Types of orthopaedic treatment in class III malocclusion.................................. 22 1. Protraction HG........................................................................................ 22 Definition....................................................................................................... 22 History........................................................................................................... 22 Indications ..................................................................................................... 22 Timing........................................................................................................... 24 Effects ........................................................................................................... 24 Protraction face mask system.......................................................................... 25 Evidence based short term effectiveness of PH ................................................ 29 Evidence based long term effectiveness of PH................................................. 29 2. Chin caps................................................................................................ 36 Types: occipital pull, used for patients with mandibular prognathism or vertical pull, used for patients with increased anterior face height ..................... 36
  • 4. Mohammed Almuzian, University of Glasgow, 2013 3 Best patient for Chin cup therapy .................................................................... 36 Ko et al (2004) ............................................................................................... 36 The effects of chincup therapy ........................................................................ 37 (Thilander 1963)............................................................................................. 37 3. Reverse chin cup therapy ......................................................................... 37 4. Bone anchored orthopaedic appliance (Bollard miniplates, PFH supported with miniplates).............................................................................................. 38 5. Shapiro and Kokich 1984 used the same idea by inducing artificial ankylosis and use the ankylosed teeth as anchor.............................................................. 39 6. Functional appliances .............................................................................. 39 Camouflage (dental compensation for mild cases)............................................ 41 Indications ..................................................................................................... 41 Techniques of camoflagable treatments ........................................................... 42 1. Non extraction......................................................................................... 42 2. Extraction: .............................................................................................. 42 Orthognathic surgery options .......................................................................... 45 The types of surgery most frequently used are the following............................. 45 Intraoperative complications of the mandibular ramus surgery ......................... 46
  • 5. Mohammed Almuzian, University of Glasgow, 2013 4 What Factors need to be taken into Account When Planning a surgical treatment for class III cases............................................................................................ 47 1. Planning the type of surgery..................................................................... 47 2. The Pre-Surgical Orthodontics in Class III?.............................................. 47 What Are the Aims of the Pre-Surgical Orthodontics?...................................... 47 Borderline Camouflage/ Orthognathic Surgery Patients.................................... 48 Summary of the evidences .............................................................................. 49
  • 6. Mohammed Almuzian, University of Glasgow, 2013 5 Class III malocclusion Definition  BSI 1982 defined class III incisor relationship as ‘’the lower incisal edge lies anterior to the cingulum plateau of the the upper incisors, British Standards Institute, 1983  The term ‘pseudo-classIII’ has been coined for this situation where an anterior displacement masking what is in fact an underlying skeletal class I base relationship. Incidence 1. Class III prevalence in white populations  3% UK (Foster & Day, 1974)  5% (Jones & Oliver, 2000)  5% UK (Todd and Dodd 1975) 2. Class III prevalence in Asian populations  4-14% in Asian (Lew 1993) 3. Dental anterior crossbite  Anterior crossbitein 10% of children (1993 Child Dental Health Survey)
  • 7. Mohammed Almuzian, University of Glasgow, 2013 6 Classification Lin (2007) divides class 3 malocclusion into three categories according to the following definitions: 1. True class 3, anterior crossbitecases with bilateral buccal occlusions in class III. 2. Class 3 subdivision, anterior crossbitecases with one of the bilateral buccal occlusions in class 1 and the other in class 3. 3. Pseudo class 3, bilateral class 1 buccal occlusions and majority of teeth in anterior crossbite. The pseudo class 3 malocclusion is often due to collapse of the arch perimeter resulted from: Caries in some Eastern societies (caries collapse) TSD or small, missing or impacted or palatal positioning of the upper teeth (perimeter-collapse). Aetiology 1. Skeletal : A. Environmental  Airway problems like enlarged tonsils & nasal blockage,  Scaring from CLP as a result of surgical repair  Hormonal like in acromegaly.
  • 8. Mohammed Almuzian, University of Glasgow, 2013 7  Some syndromes caused by environmental as well as genetic reasons such as Crouzons, Aperts, and Cleidocranial dysostosis. B. Genetic (Litton et al 1970). 1/3 of patients with severe class III have a parent with class III problems but there is no detected autosomal dominant or recessive method of transmission. 2. Soft tissue: the ST indeed my act to reduce the severity of CLIII, Lower incisor retroclination is adaptive due to soft tissue forces and tongue might procline ULS. Exception in high angle case when there is tongue to lower lip seal and macroglosia that worsen the CLIII. 3. Dental factors:  Rarely ULS retroclination and LLS proclination.  Hypodontia or microdontia in the upper arch  Impacted upper teeth 4. Habits: tongue to lower lip seal and macroglosia that worsen the CLIII. Features of Class III A. Skeletal features  Cranial base features  AP relationship  Vertical relationship  Transverse relationship
  • 9. Mohammed Almuzian, University of Glasgow, 2013 8  Cephalometric skeletal values B. Soft tissues features C. Dental features D. Displacements E. Facial growth In details F. Skeletal features 1. Cranial base features:  Short cranial baselength.  Decrease cranial baseangle resulting in forwards position of mandible. 2. AP relationship  Mainly skeletal class 3 base relationships but it could be Class I or even class II skeletal base.  Guyer, Ellis, Behrents and McNamara (1986) 55% of class 3 malocclusions had maxillary deficiency as one of the components of the malocclusion. Mandibular prognathsim in 45% of cases. 3. Vertical relationship Guyer, Ellis, Behrents and McNamara (1986), 59% of class 3 malocclusions had reduced or neutral lower facial heights and that 41% had increased lower facial heights.
  • 10. Mohammed Almuzian, University of Glasgow, 2013 9 4. Transverse relationship  The maxillary skeletal base widths were (statistically) significantly smaller in the class 3 than in the class 1group (Chen et al 2008)  Skeletal asymmetries, particularly in conjunction with mandibular prognathsim, are also relatively common in class III malocclusions (Severt and Proffit, 1997). 5. Cephalometric skeletal values  Reduced cranial base angle  Increased saddle angle  Obtuse gonial angle  Reduced ANB  Normal or increase MMP angle and lower face height  Increased mand length  Reduced maxillary length G. Soft tissues features ST not involved in aetiology but encourage dentoalveolar compensation. However there are some features which could be found in class III case depending in the aetiology of the problem: 1. Orbital rim hypoplasia 2. Increase scleral show 3. Check bone flattening
  • 11. Mohammed Almuzian, University of Glasgow, 2013 10 4. Malar hypoplasia in midface deficiency 5. Paranasal hallowing 6. Obtuse NLA 7. Reduced incisor show at smile 8. Increase buccalcorridor dark space 9. Upper lip looks thin with reduced vermilion bordershow while lower lip may be full and pendulous 10. Obtuse LMA 11. Prominent chin 12. Concave or straight profile with anterior divergence. 13. Increased throat length H. Dental features 1. Class III incisor relationship 2. Mostly CI III molar relationship could be I or even II. The same applied for canine relationship. 3. Tendency to or full reverse OJ, 4. Reduced OB, AOB may exist 5. Max probably crowded, mandible unlikely to be so but usually spaced. 6. Incisors compensate for Skeletal base, i.e. Proclined maxillary, retroclined mandibular incisors
  • 12. Mohammed Almuzian, University of Glasgow, 2013 11 7. Transverse discrepancyexpressed in a form of tendency to posterior cross bite. It could be unilateral with or without displacement or could be bilateral mainly without displacement and to lesser extent with displacement I. Displacements The displacement could be in an anterior or lateral direction or combination. It is due to:  Unsatisfactory edge-to-edge incisor  Unsatisfactory transverse buccalsegment relationship J. Facialgrowth  Tends to be unfavourable i.e. backwards growth rotation. NB: Bacceti 2007, found that the pubertal peak of mandibular growth in AP and vertical direction occurred between stages CS3 and CS4 in (corresponding with the eruption of canines and premolars) and CS4-CS6 late developmental stages (corresponding with the complete eruption of second and third molars) but 2 time more in male than female. IOTN and class III A reverse overjet  It is recorded when ALL four incisors are in lingual occlusion.  If the reverse overjet is greater than 1 mm it is important to investigate whether the individual has masticatory or speech (M&S) difficulties.
  • 13. Mohammed Almuzian, University of Glasgow, 2013 12  There are several methods of investigation but a simple approachis to ask the individual to count from 60-70 noting any difficulty in pronunciation. In addition, any signs and symptoms of mandibular dysfunction should be checked. Crossbite (2.c, 3.c, 4.c)  An anterior crossbite is when 1, 2 or 3 incisors (but not all of them) are in lingual occlusion.  A posteriorcrossbite is recorded when the posterior tooth or teeth are cusp to cusp or in full crossbitein a buccal or lingual perspective.  The grade recorded depends on the severity of discrepancybetween retruded contact position (RCP) and intercuspal position (IP) (Table 3.4).  The greater the discrepancy between RCP an IP, the higher the grade Growth status assessmentfor class III patients Mandibular skeletal maturity can be assessed by means of a series of biologic indicators:
  • 14. Mohammed Almuzian, University of Glasgow, 2013 13 1. History (is the patient changing shoes) 2. Growth chart like an increase in bodyheight (Nanda, 1955; Hunter, 1966) 3. Biological parameters like:  Skeletal maturation of the hand and wrist (Bjork, 1967) or cervical vertebral maturation (CVM) method. Franchi 2000, Beccteti 2002 & 2005 (please read the summary about ‘’TheCervical Vertebral Maturation’’)  Dental development and eruption (Bjork, 1967)  Chronological age  Secondarysexual features like Menarche, breast, and voice changes (Tanner 1962) Monitoring the growthof mandible 1. Serial Clinical measurements like OJ 2. Serial Study models 3. Serial Photograph or 3D stereo photogrammetry 4. Serial Ceph (not justified) 5. Growth Treatment ResponseVector (GTRV) analysis  Ngan (2005) has described this as a method of determining whether a class 3 malocclusion can be treated by camouflage or if surgical treatment will be required at a later date.  It is calculated from two serial cephalometric radiographs at least one year apart.
  • 15. Mohammed Almuzian, University of Glasgow, 2013 14  The lines AO and BO are constructed in the same way as for the Wits analysis on the first radiograph;  The first radiograph is then superimposed on the second using the stable structures of the cranial base.  New AO and BO are then constructed using the occlusal plane of the first radiograph.  Horizontal growth change of maxilla is second AO-first AO  Horizontal growth change of mandible is second BO-first BO  The GTRVis then given by the following formula:  GTRV = horizontal growth change of maxilla / horizontal growth change of mandible  The normal GTRV of patients is 0.77 – ie: normally, mandibular growth usually exceeds maxillary growth by 23% between the ages of 8 and 16 years. Differentiation betweenmandibular prognathsim & maxillary deficiency Maxillary deficiency Mandibular prognathism Frontal Tendency to show sclera Normal show of sclera Sallow paranasal form Normal paranasal form Narrow alar base width Normal alar base
  • 16. Mohammed Almuzian, University of Glasgow, 2013 15 width Tendency of upper lip to be thin Normal upper lip Normal chin projection Prominent chin Normal to decreased lower facial height (LFH) Normal, increased or decreased lower facial height (LFH) Profile Nasolabial line-Subnasale: subnasale-tip of nose ,usually not 1:1 ratio Normal Nasal tip down Normal Obtuse nasolabial angle Normal nasolabial angle Smiling assessment Less incisor visible Good Cephalometric assessment Normal to decreased total facial height Increased total facial height Short Pty-ANS normal Facial concave Anterior divergent Normal ramus width Narrow
  • 17. Mohammed Almuzian, University of Glasgow, 2013 16 Gonial angle normal obtuse Occlusal Assessment Tendency toward crowding and missing teeth in the upper Spacing in lower arch Transverse deficiencies noticeable in maxillary arch Normal Treatment options for class III malocclusion McIntyre 2004 1. Accept 2. Interceptive treatment 3. Growth modification 4. Orthodontic camouflage 5. Orthodontic decompensation and orthognathic surgery 6. Compromised orthodontic treatment Factors influencing treatment options in Class III 1. Patient concern(dental or facial concern) 2. Patient age 3. Growth 4. Medical condition
  • 18. Mohammed Almuzian, University of Glasgow, 2013 17 5. Patient compliance 6. Family history of class III 7. Severity of skeletal problem in AP, V & T direction 8. Clinical condition of the teeth and oral tissues. 9. Amount of the OJ &OB 10. Degree of crowding 11. Degree of compensation 12. Presence of displacement Summary about treatment strategies according to dental age a. In primary dentition There is no evidence to suggest that orthodontic intervention during the primary dentition avoids, or reduces, the complexity of later orthodontic treatment. b. In early mixed dentition 1. Incisor crossbites due to retained primary incisors: Treatment extract retained primary teeth 2. Premature contact and mandibular displacement or incisors erupted in cross bite relationship, then  Extract or grind cusp tips (usually primary canines)  Posterior onlay to overcome the posterior crossbitethat caused displacement.
  • 19. Mohammed Almuzian, University of Glasgow, 2013 18  Procline maxillary permanent incisor(s) using an upper removable appliance (URA) or a fixed appliance (4 x 2 appliance which is well tolerated less dependent on compliance (Sandler, 2001) Offer three-dimensional control  Anterior cross elastics, Reynolds method 1978  Expand by URA or Q helix….. c. Mid-Late mixed dentition  Class III incisors with deep overbite and mild/moderate skeletal Class III: Protraction headgear and rapid maxillary expansion  Proclined lower incisors: URA incorporating inverted labial bow or URA to procline ULS. d. Early permanent dentition 1. Mild/moderate skeletal discrepancy  with no concern about facial appearance or growth , Procline maxillary permanent incisors using URA/fixed appliance or Camouflage skeletal pattern using fixed appliances with or without extraction.  With concern about facial appearance or growth A. Postponetreatment decision until skeletal growth completed. B. sometime, Align maxillary arch with fixed appliance and relieve crowding, accepting Class III incisor relationship will require orthognathic surgery in adulthood 2. Severe skeletal discrepancy or a concern about facial appearance
  • 20. Mohammed Almuzian, University of Glasgow, 2013 19  Accept malocclusion will require combined orthodontic treatment/orthognathic surgery in adulthood  Align maxillary arch with fixed appliance and relieve crowding, accepting Class III incisor relationship will require orthognathic surgery in adulthood e. Adult treatment 1. Mild/moderate skeletal discrepancy A. no concern about facial appearance  Procline maxillary permanent incisors using URA/fixed appliance  Camouflage skeletal pattern using fixed appliances B. Mild/moderate skeletal discrepancy –concernabout facial appearance  Compromised treatment by aligning the UA with or without extraction and if possible align lower arch on non-extraction base to keep the cop of decompensation if the Combined orthodontic treatment/orthognathic surgery decided later 2. Severe skeletal discrepancy with no concern about facial appearance  Compromised treatment by aligning the UA with or without extraction and if possible align lower arch on non-extraction base to keep the cop of decompensation if the Combined orthodontic treatment/orthognathic surgery decided later 3. Severe skeletal discrepancy with a concern about facial appearance  Combined orthodontic treatment/orthognathic surgery
  • 21. Mohammed Almuzian, University of Glasgow, 2013 20 Reasonsfor early treatment of class 3 malocclusions Hägg et al (2004) and Ngan (2005) cite the reasons for early treatment as: a. To eliminate CR-CO discrepancies which may cause  periodontal damage  occlusal wear  TMJ problems b. To provide a more favourable environment for growth and development of the maxilla and mandible with a reduction in dental compensation because remodelling may occurin the joint as the postured position which will act as functional appliance and making correction of the crossbite more difficult at a later date c. To provide spacefor the eruption of the buccalsegments as a result of proclination of the upper incisor so the canines and premolars can be guided into a class 1 relationship d. Psychological benefits resulting from improved dental and facial appearance Orthopaedic treatment option Effectof orthopaedic appliance in class III maloculsion Dermaut and Aelbers (1996) have reviewed the possible effects of orthopaedic treatment in class 3 malocclusions. 1. 50% of the studies showed stimulation of maxillary growth
  • 22. Mohammed Almuzian, University of Glasgow, 2013 21 2. 90% showed an inhibition of mandibular projection  In general orthopaedic appliances are more effective if cl3 is due to maxilla retrusion than mand prognathism.  However, most of the effects are dentoalveolar in nature with maxillary incisor proclination and mandibular retroclination. Predictive factors for orthopaedic treatment 1. Patient’s factors  good co-operation  No familial prognathism 2. Growth  Young growing patient 3. Soft tissue  Acceptable facial aesthetics 4. Skeletal  Mild skeletal discrepancy (ANB < -20 )  Normal MMPA  No asymmetries (Symmetrical condylar growth) 5. Dental  -2mm reverse OJ or edge to edge relationship
  • 23. Mohammed Almuzian, University of Glasgow, 2013 22  Minimal dental compensation 6. Displacement  Functional shift Types of orthopaedic treatment in class III malocclusion 1. ProtractionHG Definition Means of applying anterior directed forces to teeth and/or skeletal structures from an extra-oral source History  The technique of maxillary protraction is based on work by Nanda (1978), with rhesus monkeys in which he showed that a force of approximately 500g could produceanterior displacement of the maxilla  It is appropriate to refer to this type of treatment as facemask therapy. Indications A. Treatment of maxillary retrusion. An ideal case would be; 1. Patient’s factors  good co-operation  No familial prognathism
  • 24. Mohammed Almuzian, University of Glasgow, 2013 23 7. Growth  Young growing patient 8. Soft tissue  Acceptable facial aesthetics 9. Skeletal  Mild skeletal discrepancy (ANB < -20 )  Normal MMPA  No asymmetries (Symmetrical condylar growth) 10. Dental  -2mm reverse OJ or edge to edge relationship  Retroclined ULS  Proclined LLS 11. Displacement  Functional shift B. Reinforcement of anterior anchorage and dental protraction allowing closure of spacefrom behind in patients suffering from hypodontia C. Stabilization following maxillary osteotomy/distraction osteogenisis D. Rotate arch segments in cleft palate patients E. Remove hyper-anterior contact in TMJ internal derangement cases,
  • 25. Mohammed Almuzian, University of Glasgow, 2013 24 Timing 1. Dental age: McNamara (1987) suggested that the optimal time for treatment is in the early late mixed dentition, coincident with the eruption of the upper permanent incisors. 2. Skeletal age: Baccetti et al (1998) showed that the early treatment group CVM2 showed effective forward displacement of the maxillary structures whereas the late treatment group CVM3 showed no change compared with controls 3. Chronological age: Other investigators have suggested that for optimal orthopaedic effects, treatment should be initiated before the patient is 9 years old (Proffit, 2000). Mandal 2010, 2012 used it at age of 8.5-10 year. Kim et al., 1999, meta-analysis of effectiveness of protraction HG concluded it was less effective on patients >10yrs Effects 1. Correction of a centric occlusion-centric relation discrepancy. This correction happens relatively rapidly in patients with an edge to edge relationship and associated displacement 2. Maxillary skeletal protraction, with up to 3mm of forward movement of the maxilla possible , Mandal 2010 and 2012, showed that these effect are stable after 3 years follow-up 3. Proclination and forward movement of the maxillary dentition 4. Lingual tipping of the lower incisors 5. Redirection of mandibular growth in a downward and backward direction, resulting in an increase in lower anterior facial height
  • 26. Mohammed Almuzian, University of Glasgow, 2013 25 Protractionface mask system A. Types Extraoral part 1. ProtractionHeadgear(Hickham) 2. FacialMask (Delaire) 3. Suborbital ProtractionAppliance (Grummons)  Advantages: frame more rigid, no force on TMJ, no LLS retroclination, easy to adjust and wear during sleep  Disadvantages: not esthetic due to midfacial support 4. 4. Nola protraction appliance 5. Petit style face mask The Petit style with a single central vertical bar is also well tolerated and recent price changes have made it economically much more attractive. B. Intraoral part:
  • 27. Mohammed Almuzian, University of Glasgow, 2013 26 1. In order to maximize the amount of skeletal change in young children, a removable full coverage acrylic splint is used with a protraction headgear (Proffit 1986). 2. McNamara (1987) has described the use of a Biocryl and wire splint that is bonded in the mouth. The splint material should be at least 3 mm thick with a 0.045" stainless steel wire framework. The two halves of the splint are joined by an expansion screw. Traction hooks to receive the elastics from the headgear are placed in the first premolar region. 3. RME with hook can be used 4. Fixed appliance 5. Some recommend using an intraoral bone plate to supportthe PHG force. Systematic review to compare the dentally anchored face mask with skeletally anchored one by Major (2012) in Canada, he found Approximately 3 mm of horizontal A-point movement is predictably attainable with the skeletal one in comparison to dental one.. C. Rapid maxillary expansion Advantages (Haas 1973). 1. Sutural loosening 2. Correct transverse discrepancy that commonly associated with class III malocclusion 3. Displace the maxillary complex anteriorly. This is due to butterfly effect of expansion at the Midpalatal suture and becauseof the anterior sloping of the facial sutures
  • 28. Mohammed Almuzian, University of Glasgow, 2013 27 Evidences 1. Many clinicians use protraction with a facemask following or simultaneously with palatal expansion, because some evidence suggests that the expansion makes antero-posterior skeletal change more likely. Kim et al (1999) 2. There is other evidence that the expansion is optional and should be dictated by the maxillary arch width related to the lower arch width, Vaughan 2001 and 2005. D. Techniques  First step is to fabricate and bond/cement the rapid maxillary expansion appliance  Appliance is activated once per day until the desired increase in maxillary width has been obtained.  If patients do not need an increase in maxillary width, the appliance is still activated for 7-10 days to disrupt the maxillary sutural system and promote maxillary protraction (Haas, 1965)  After the patient activated the maxillary appliance for 7-10 days protraction headgear is fitted. E. Forcelevel 1. Moving maxillary anterior teeth forward: 400g per side, 12-14h/day 2. Maxillary protraction : 800g per side, 14h/day 3. Overcorrect to compensate for mandibular growth 4. Active treatment should be limited to 9-12 months because of the risk of decalcification of the dentition F. Forcedirection: 1. To avoid bite opening, place protraction elastics near maxillary bicuspids, 2. Forcevector should be 15-30 degree below the horizontal
  • 29. Mohammed Almuzian, University of Glasgow, 2013 28 3. To avoid irritation to the lip, use crossed elastic, 4. Pay special attention to airway and tongue posture 5. Ishii et al (1987) describe the effects of providing the protraction force from the first molars or the premolar region. Protraction from the first molars results in more anterior movement and a forward and upward rotation of the maxilla; protraction from the premolars results in less forward movement but fewer tendencies to upward and forward rotation. G. Transitional period After treatment objectives have been achieved, the patient can be retained with a number of appliances:  The facemask,  FR-3 appliance  Acrylic maxillary retainer with reverse lower labial bow  Chin cup (seldom used). H. Postprotraction treatment consideration 1. As mandibular growth exceeds maxillary growth during adolescence, early Class III correction may be lost during the teenage period. The patients and parents should again be warned of the possibility of orthognathic treatment if growth is unfavourable 2. Upper labial root torque during fixed appliance stage: Most class 3 patients demonstrate considerable proclination of the upper labial segment at the end of treatment. Catania et al (1990) recommend in his case report to use inverted U incisor bracket to counteract the effect of proclination.
  • 30. Mohammed Almuzian, University of Glasgow, 2013 29 Evidence based short term effectivenessofPH Mandall, 2010 (similar to study of Ngan 1998)  Early Class III orthopaedic treatment with protraction face mask in patients less than 10 years of age is skeletally and dentally effective in the short term 15 months. (After 15 months of treatment, children undergoing early facemask therapy had 1.3 degrees more forward movement of SNA, almost 2degrees less forward movement of SNB and an overall ANB improvement of around 2.6 degrees when compared to the controlgroup. In addition, the overjet improved by more than 4 mm and the relative PAR scoreby more than 40% in the facemask compared to the control group. Thus, early class III protraction facemask treatment in patients under 10 years of age would seem to be skeletally and dentally effective in the short-term)  70% of patients had successfultreatment, defined as achieving a positive overjet.  Early treatment does not seem to confer a clinically significant psychosocial benefit.  No TMJ problem Evidence based long term effectivenessofPH  Mandal 2012:Early Class III orthopaedic treatment with protraction face mask in patients less than 10 years of age is skeletally and dentally effective after 3 years of treatment.  Masucci 2011: RME/FM therapy led to successfuloutcomes in about 73% of the patients. Significantly improved sagittal dentoskeletal relationships. These
  • 31. Mohammed Almuzian, University of Glasgow, 2013 30 favourable changes were mainly due to significant improvements in the sagittal position of the mandible, but the maxillary changes reverted completely in the long term. This treatment not induces a tendency of bite opening or increased vertical relationship.  A Cochrane review by Watkinson in 2013. This review looked at the use of four different types of orthodontic treatment for correcting prominent lower front teeth in children.-Facemask-Chin cup-Mandibular -Tandem traction bow appliance. This review found some evidence that the use of a facemask appliance can help to correctprominent lower front teeth on a short-term basis. There was no evidence available to show whether or not these short-term changes will still be maintained until the child is fully grown. There was not enough evidence to supportany other types of treatment for prominent lower front teeth. 2. Alternate Rapid Maxillary Expansion and Constriction(Alt- RAMEC)  Original technique:  A protocolof maxillary protraction developed by Liou and Tsai in 2005.  It includes 3 components:a 2-hinged rapid maxillary expander, repetitive weekly protocolof Alternate Rapid Maxillary Expansion and Constriction (Alt-RAMEC), and intraoral maxillary protraction springs.  The innovative part of this technique is the sutural loosening accomplished by alternating expansion with constriction for 8 weeks.
  • 32. Mohammed Almuzian, University of Glasgow, 2013 31  This backand- forth motion can mobilize the maxilla and protract the maxilla for longer distances. Liou 2005  The Alt-RAMEC protocolthe maxilla is expanded for 7 consecutive days and constricted for 7 consecutive days for 9 weeks. After the Alt-RAMEC technique, the maxilla is protracted with protraction springs for 3 months. The technique has been modified to use a standard Hyrax rapid maxillary expansion appliance and fixed orthodontic appliances in the lower arch, Class III
  • 33. Mohammed Almuzian, University of Glasgow, 2013 32 elastics and reverse-pull headgear or facemask (Yen 2011). The Clinical Protocol for Maxillary Protractionina Typical Adolescent Patient With Cleft Lip and Palate ● At age 13, the patient chooses surgery or maxillary protraction. Maxillary expansion and protraction was performed before dental alignment with an archwire because additional space was created with arch expansion. If maxillary dental crowding was present, extractions were deferred until after expansion and protraction. The exceptionsto this rule were the patients who had molars and premolars tilting in oppositedirectionswhich would prevent parallel draw of bands. These patients received limited orthodontics with sectional wires to improve the insertion and draw of a rapid palatal expander (RPE). ● Pretreatment records. Check for parallel path of insertion of RPE along anchor teeth. Prior alignment is needed if teeth are tilted in oppositedirections. ● Banding of the lower first and second molars, bonded orthodontic brackets for the lower arch premolars and anterior teeth. Initiate leveling of mandibular dentition. Stabilize lower dentition in a stainless steel rectangular archwire; ● Banding maxillary molars and premolar (or canines) for a Hyrax rapid palatal expander placed high in vault of palate. ● Delivery of Hyrax expander. Demonstration of screw turns needed to expand and constrict the Hyrax expander. Sutural loosening is initiated by activating the appliance 2 turns in the morning and 2 turns in the evening. The expansion rate is 1 mm/d. The screw turns follow the same direction for 1 week.
  • 34. Mohammed Almuzian, University of Glasgow, 2013 33 ● At the end of the week, the patient returns to the clinic to demonstrate ability to insert the swivel key into the screw of the Hyrax expander. The swivel key is suspended in the RPE before activation to ensure that the key is fully inserted. The reverse direction is taught so that patient so that he/she is proficient in both directions with the swivel key. ● Expansion and constriction is alternated each week. Recall after 4 weeks. ● After 8 weeks of alternating expansion with constriction, the facemask and Class III elastics are given to the patient to start protraction. The patients are instructed to wear the facemask at night to “pull” the maxilla forward and wear the Class III elastics during the day to “hold” the results obtained by the facemask. Expansion and constriction are continued during protraction. The facemask bar for protraction elastics is placed at the level of the lower lip to provide a slight downward direction of pull from the premolar bands in the Hyrax expander. The facemask is used with elastics to the premolar bands during the evening. Heavy force Class III elastics are placed from hooks anterior to the mandibular canine to the maxillary first molar bands of the Hyrax expander 24 hours/day with intermittent changes before and after meals. The elastics are stretched to their elastic limit to maximize force. ● After 2 weeks, the patient returns to demonstrate ability to use facemask and intraoral elastics. Some correction, such as edge-to-edge occlusion should have occurred by this time. The elastics are changed to heavier and shorter elastics as the distance between RPE and headgear is shorter.
  • 35. Mohammed Almuzian, University of Glasgow, 2013 34 ● Continue the facemask and Class III elastics until the underbite is over corrected into a Class II malocclusion by at least 3 mm. Maintain the correction with 24-hour Class III elastics. ● After 4 months, remove RPE and replace with maxillary brackets and bands for orthodontic alignment. ● Class III elastics are used for 18 months during the arch alignment, finishing and retention stages of treatment. Masucci1 2014, (retrospective control trial)) (young children aged 6.1 yers) Both the Alt-RAMEC/FM and the RME/FM protocols showed significantly favorable effects leading to correction of the Class III malocclusion. The Alt-RAMEC/FM protocolproduced a more effective advancement of the maxilla (SNA +1.2°) and greater intermaxillary changes (ANB +1.7°) vs. the RME/FM protocol. No significant differences were recorded as for mandibular skeletal changes and vertical skeletal relationships. Effectiveness of maxillary protraction using facemask with or without maxillary expansion: a systematic review and meta-analysis, Foersch, 2015. The statistical analysis of treatment changes advocates a positive influence on sagittal maxillary development, which is not primarily influenced by transverse expansion. Dental side effects are more distinct when no expansion was carried out. Forthe concept
  • 36. Mohammed Almuzian, University of Glasgow, 2013 35 of alternating activation/deactivation of the expansion appliance (alt-RAMEC), two articles of high methodological scoring were identified. They indicate an enhancement of face mask treatment.The findings are consistent with results of previous literature studies regarding the efficiency of class III face mask treatment. A further need for more randomized controlled studies was identified especially with regard to the new conceptof alternating maxillary expansion and compression, which showed a positive influence on the maxillary protraction based on two studies. Clinical relevance Class III therapy using extraoral face mask anchorage is effective for maxillary protraction. The recently discussed new protocols potentially improve this treatment. 3. Tandem traction bow appliance: attachments are fixed to the top and bottom teeth. In the top attachment there is a hook on each side. A metal bar is placed in the lower attachment, which sits in front of the lower teeth. An elastic band can then be placed on each side to pull the top jaw forward and bottom jaw backwards, to correctthe prominent lower teeth
  • 37. Mohammed Almuzian, University of Glasgow, 2013 36 4. Chin caps  The idea of this appliance is that because the condyle is a growth site, the growth impeded by extra-oral force (Graber, 1977).  Despite success in animal experiments, most human studies have found little difference in mandibular dimensions between treated and untreated subjects (Sugawara et al, 1990).  Chincup appliances greatly improve the skeletal profile in the short term such changes are however rarely maintained during the pubertal growth spurt  Force500g per side 12-14 h/day for 4-5 years. Once the anterior crossbite was corrected, the patient was instructed to wear the chin cup at least 10 hours per day until slight Class II canine and molar relationships were established.  The bestage is before canine and premolar erupt (CS2-CS3maturity) this is the first growth spurt of mandible, the second one when 7 and 8 erupt CS4-CS6 (Bacceti, 2005).  Types: occipital pull, used for patients with mandibular prognathsim or vertical pull, used for patients with increased anterior face height Bestpatient for Chin cup therapy Ko et al (2004) 1. Mild Skeletal III, ability to achieve edge to edge incisors 2. Short vertical facial height (.Chincup cause clockwise rotation of the mandible. 3. Proclined or upright LLS (Chincup cause lingual tipping of the lower incisors (Thilander 1963) 4. Absence of severe facial and dental asymmetry
  • 38. Mohammed Almuzian, University of Glasgow, 2013 37 The effects ofchincup therapy (Thilander 1963)  Retardation of mandibular growth. Effective at reducing mandibular prognathism before puberty but this is then lost with continual growth, Sugawara et al., 1990  Remodelling of the condyle and glenoid fossa  Backward rotation of the mandible  Closure of the gonial angle  Result in lingual tipping of LLS, 5. Reverse chin cup therapy  Developed in Germany in 2012 by Rahman 2012 show similar result when the reverse chin cup therapy compared to face mask therapy in RCT involving 42 samples at age of 8-9 years.  Reverse chin cup therapy is able to produceforward movement of the maxilla in the growing child associated with lingual tipping of the lower incisors and labial tipping of the uppers.
  • 39. Mohammed Almuzian, University of Glasgow, 2013 38  The point of application of protraction elastics from the upper removable appliances was similar for both groups. All patients received the same protraction force of 500 g per side with a 30 degree downwards pull.  The proposedadvantages of the new reverse chin cup design were that it was smaller and less bulky than other protraction appliances, therefore encouraging children to wear it. 6. Bone anchored orthopaedic appliance (Bollard miniplates, PFH supported with miniplates)  Plate comes in different size and form. It should be adapted to the bone surface and fixed with 2.5mm width and 5mm length screw.  Heavy Class 3 elastic used  Age of 9-13  Forceabout 150gm 24h per day. Loading start 3 weeks after plate insertion.  The major problem with this technique is the low rigidity of bone for young patient which affect stability of bone plate and the presence of teeth follicle which might cause problem with implant insertion. Also plate removal is problematic bec it needs surgery and sometime the bone grow over the screw.  Success rate 92% with 3mm improvement of maxilla position and zygoma. (Nguyen 2011) (De Clerck 2011)  This approachhas two advantages:
  • 40. Mohammed Almuzian, University of Glasgow, 2013 39 1. it is clearly more effective than a facemask to a maxillary splint and also appears to producemore skeletal change than has been reported with facemasks to anterior miniplates 2. wearing an Extraoral appliance is not necessary and nearly full-time application of the force can be obtained. 7. Shapiro and Kokich 1984 usedthe same idea by inducing artificial ankylosis and use the ankylosedteeth as anchor. 8. Functional appliances Reverse twin block a. The design included  Cantilever springs behind the upper incisors,  A midline expansion screw,  A lower labial bow  Intersecting blocks at 70 degrees with a vertical height of 7 mm.  Block on U4s,5s and L5s,6s b. The patient was instructed to wear the appliance on a full-time basis initially, activating the midline expansion screw twice a week. c. Effects:  There is no sustained effect on growth of either the maxilla or mandible. Reverse TB for mandibular prognatisim (Ucem 2004 claim that it producedental effect only) Although there is a reduction in SNB and an increase in ANB due to
  • 41. Mohammed Almuzian, University of Glasgow, 2013 40 the backwards and downwards rotation of the mandible and an increase in lower face height. Therefore, this type of treatment is inappropriate for high angle cases with an already increased FMPA.  Seehra 2012, compare the effectiveness of Reverse Twin-Block therapy (RTB) and protraction face mask treatment (PFM) with respect to an untreated control in the correction of developing Class III malocclusion. Both appliances are capable of correction of Class III dental relationships; however, the relative skeletal and dental contributions differ. Skeletal effects, chiefly anterior maxillary translation, predominated with PFM therapy. The RTB appliance induced Class III correction,  Primarily as a result of dentoalveolar effects and by clockwise rotation of the mandible. The FR 3  They are designed to rotate the mandible downward and backward, and to guide the eruption of the teeth so that the upper posterior teeth erupt down and forward whilst eruption of the lower teeth is restrained. This rotates the occlusal plane in the direction that favours correction of a class III molar relationship.  These appliances also tip the mandibular incisors lingually and the maxillary incisors labially, introducing an element of dental camouflage for the skeletal discrepancy.  In theory, the lip pads stretch the periosteum in a way that stimulates forward growth of the maxilla. .
  • 42. Mohammed Almuzian, University of Glasgow, 2013 41 Camouflage (dental compensationfor mild cases) Indications 1. Growth  Patient pastpeak growth  Non-progressive worsening of the Class III. 2. Skeletal  Class I or mild class III skeletal base relationship;  Average or reduced lower face height; 3. Dental  Average or increased overbite;  Minimal reverse OJ or edge-edge relationship  Proclined lower incisors;  Upright or retroclined upper incisors;  Molar relationship less than half unit Cl Ill 4. Soft tissues features 1. Patient not concern about the profile 2. Favourable softtissue features 5. Displacement
  • 43. Mohammed Almuzian, University of Glasgow, 2013 42  Anterior displacement on closing from RCP into ICP. Techniques of camoflagable treatments 1. Non extraction  Expansion in upper arch to relieve crowding, eliminate crossbites and mandibular displacements  Procline upper incisors, retrocline lower incisors (it is unwise to procline the upper incisors beyond 120 degrees to the maxillary plane or retrocline the lower incisors beyond 80 degrees to the mandibular plane.) 2. Extraction: Aims of extraction  To relieve crowding or ML,  Correct incisor inclination  Correction of class III  To achieving a positive overjet  To achieving a positive overbite  To constrict the lower arch in order to correct any transverse problems Options of extraction:  Extraction upper 5`s to maintain U lip support+ lower 4`s to allow LLS retroclination.
  • 44. Mohammed Almuzian, University of Glasgow, 2013 43  Extraction of 4x4.  Extraction of a single lower incisor: If the upper arch is well-aligned but spaceis required to align and retrocline the lower incisors, extraction of a single lower incisor can be an option (Zachrisson 1999) but it may leave some black triangle and gingival recession. This decision depend on the presence of (large IC distance, minor crowding, TSD in LLS, square shape L incisors not triangular). A better approachto camouflage in patients of European descentwith a moderately severe Class III problem is extraction of one lower incisor, which prevents major retraction of the lower teeth, while the maxillary incisors are moved facially with some tipping allowed. The combination of upright mandibular incisors and proclined maxillary incisors often leads to good dental occlusion rather than the expected tooth-size problem, but a wax setup always should be done when one lower incisor extraction is considered to verify the probably occlusal outcome.  Proffit 2013, For Asian (or rarely, other) Class III patients with major protrusion of the lower incisors, using skeletal anchorage to move the whole lower arch posteriorly can be quite helpful in correcting the problem. Extraction of third molars usually is needed in order to move the mandibular dental arch back. If second molars are extracted to facilitate distal movement, third molars may erupt as satisfactory replacements, but this is not as likely as in the maxillary arch and therefore is not recommended as a routine procedure. Bracket setup  To get further proclination of ULS, use MBT in the ULS  Lingual crown torque on LLS
  • 45. Mohammed Almuzian, University of Glasgow, 2013 44  Contra-lateral canine brackets (to avoid LLS proclination) Mechanics  Lacebacks in LA (to avoid LLS proclination)  Cinch back in LA (to avoid LLS proclination)  Banding 7`s to increase posterior anchorage to retract lower dentition  Closing spaceon a round wire in the lower arch will facilitate retroclination of the lower incisors.  CIII elastics (better to use short class III elastic to avoid posterior teeth overeruption)  Avoid distal headgear forces on maxilla in C3 patients NB: do not extract in lower arch if surgery is anticipated Transverse problem can be addresses by: 1. URA 2. Q helix 3. RME 4. If more than 8mm, Surgically assisted RME 5. Constriction of the LA 6. AW expansion of the UA 7. Auxillary AW in the UA
  • 46. Mohammed Almuzian, University of Glasgow, 2013 45 Orthognathic surgery options The types of surgery most frequently used are the following. 1. Sagittal split ramus osteotomy(SSRO)or bilateral sagittal split osteotomy (BSSO) to set the mandible backward 2. Intraoral vertical ramus osteotomy(IVRO) or vertical subsigmoid osteotomy (VSSO) or vertical or oblique subcondylar osteotomy(VSO) is different names for the same technique using an intraoral approach. This type of surgery is used to reduce the size of the mandible (Cheung 2002). Contraindicated in predisposed toward developing obstructive sleep apnea syndrome (OSAS) (Turnbull 2000; Chen 2005). 3. Mandibular step osteotomy(MSO). This is a surgical technique on the mandible that is performed in the anterior region of the mental foramen. It is indicated for correcting the size of the mandible by using the spaceresulting from the extraction of a posterior tooth or for closing spaces caused by lost posterior teeth. MSO enables vertical and transversal modifications to the dental arches: closure of an anterior open bite and correction of the reverse curve of Spee. This type of osteotomy presents stepwise sectioning, which allows the bone segments to be brought together as much as possible, thereby ensuring their stability. The fixation is accomplished with a miniplates on each side (Cheung 2002).
  • 47. Mohammed Almuzian, University of Glasgow, 2013 46 4. Surgically assisted rapid palatal expansion (SARPE) to correctthe combined transverse problems 5. Le Fort I (total maxillary osteotomy), the combination of Le FortI and Le Fort III, or Le Fort II in one operation or different operations. Sugaya 2012 Cochrane review two randomized controlled trials were included in this review. There are different types of surgery for this type of malocclusion but only trials of mandible reduction surgery were identified. One trial compared intraoral vertical ramus osteotomy(IVRO) with sagittal split ramus osteotomy (SSRO)and the other trial compared vertical ramus osteotomy(VRO) with and without osteosynthesis. Neither trial found any difference between the two treatments. The trials did not provide adequate data for assessing effectiveness of the techniques described Complications of the mandibular ramus surgery 1. Fractures of the osteotomised segments, 2. Incomplete sectioning (Van Merkesteyn 1987), 3. Infection, necroses, persistent paresthesia, 4. Reduced mouth opening, nausea, airway disturbance (Yamada 2008), 5. Reduced mandibular movement range (Yazdani 2010). 6. Trauma to the inferior alveolar nerve,
  • 48. Mohammed Almuzian, University of Glasgow, 2013 47 What Factors needto be takeninto Account When Planning a surgical treatment for class III cases 1. Planning the type of surgery The required surgery is planned around the aetiology of the skeletal discrepancy taking into account facial aesthetics, stability of the result, TMJ and airway, little morbidity. Allows the decision to make regarding whether the maxilla is to be advanced or the mandible set back, or a combination of these. 2. The Pre-SurgicalOrthodontics in Class III? The pre-surgical orthodontics is planned around the surgery required to achieve optimal aesthetics with the best achievable occlusion. Three important points need to be considered; 1. Expansion: Assessment of arch co-ordination using the pre-treatment models in a class I position will identify the extent of any required expansion of the maxillary arch. If minimal expansion is required, this can be achieved using the orthodontic archwires during pre-surgical orthodontics. 2. Reverse Target overjet: The planned surgical moves for optimal aesthetics dictate the reverse overjet required pre-surgically. 3. Inclination of the ULS which is determined by the degree of maxillary impaction while the inclination of LLS would be determined by the amount of autorotation. What Are the Aims of the Pre-SurgicalOrthodontics? 1. Alignment 2. Levelling and alignment of the arches.
  • 49. Mohammed Almuzian, University of Glasgow, 2013 48 3. Arch co-ordination. 4. Decompensation: In this case, decompensation of the upper and lower arches was required to producean appropriate reverse overjet pre-surgically and allow the desired surgical movements to be carried out to promotethe desired facial change. 5. Maintenance of the centre line with the mid-point of the chin in Lower teeth and philtrum in the upper teeth. Borderline Camouflage/ Orthognathic Surgery Patients The decisionwill depend on 1. Growth where there is any doubtabout further skeletal growth (principally mandibular), orthodontic camouflage should be deferred, possibly until the remaining skeletal growth has been expressed. In class III cases with a significant skeletal component, the mandible will tend to grow more and later than in class I individuals (Baccetti et al, 2007). 2. Any concerns aboutfacial appearance. 3. Medicaland family history 4. Severity of the underlying skeletal problem 5. Presence or absence of functional displacement 6. Degree dentoalveolar compensation 7. Amount of crowding, OJ, OB
  • 50. Mohammed Almuzian, University of Glasgow, 2013 49 8. Vertical height 9. Cephalometric Yardsticks A. Kerr et al 1992 in Glasgow showed that surgery is indicated for patients with  ANB <-4°  Maxillary mandibular ratio = 0.84  Lower incisor inclination (LI/MP <= 83°)  Soft tissue profile Holdaway angle > = 3.5° (Holdaway angle means soft tissue nasion-soft tissue pogonion labrale superius)  Interestingly, vertical dimension had little influence on treatment decision. B. Stellzig-Eisenhauer et al (2002) surgery indicated when Wits analysis value of –12.2 ± 4.3 mm or more while camouflage indicated when Wits value is -4.6 ± 1.7 mm or less. Summary ofthe evidences  BSI 1982 defined class III incisor relationship as ‘’the lower incisal edge lies anterior to the cingulum plateau of the upper incisors, British Standards Institute, 1983  3% UK (Foster & Day, 1974)  Anterior crossbitein 10% of children (1993 Child Dental Health Survey)  Lin (2007) divides class 3 malocclusion into three categories  Guyer, Ellis, Behrents and McNamara (1986) 55% of class 3 malocclusions had maxillary deficiency as one of the components of the malocclusion. Mandibular
  • 51. Mohammed Almuzian, University of Glasgow, 2013 50 prognathism in 45% of cases.  Guyer, Ellis, Behrents and McNamara (1986), 59% of class 3 malocclusions had reduced or neutral lower facial heights and that 41% had increased lower facial heights.  The maxillary skeletal base widths were (statistically) significantly smaller in the class 3 than in the class 1group. (Chen et al 2008)  Skeletal asymmetries, particularly in conjunction with mandibular prognathism, are also relatively common in class III malocclusions (Severt and Proffit, 1997).  Growth status assessment for class III patients 1. Mandibular skeletal maturity can be assessed by means of a series of biologic indicators: 2. Increase in bodyheight (Nanda, 1955; Hunter, 1966) 3. Skeletal maturation of the hand and wrist (Bjork, 1967) 4. Dental development and eruption (Bjork, 1967) 5. Menarche, breast, and voice changes (Tanner 1962) 6. Cervical vertebral maturation (CVM) method. Franchi 2000, Beccteti 2002 & 2005 (please read the summary about ‘’TheCervical Vertebral Maturation’’)  Growth Treatment ResponseVector (GTRV) analysis, Ngan (2005) has described this as a method of determining whether a class 3 malocclusion can be treated by camouflage or if surgical treatment will be required at a later date.  Treatment options for class III malocclusion, McIntyre 2004  Procline maxillary permanent incisor(s) using an upper removable appliance (URA) or a fixed appliance (4 x 2 appliance which is well tolerated less dependent on compliance (Sandler, 2001) Offer three-dimensional control  Reasons for early treatment of class 3 malocclusions, Hägg et al (2004) and Ngan
  • 52. Mohammed Almuzian, University of Glasgow, 2013 51 (2005) cite the reasons for early treatment  The technique of maxillary protraction is based on work by Nanda (1978), with rhesus monkeys in which he showed that a force of approximately 500g could produceanterior displacement of the maxilla  Timing, Dental age: 1. McNamara (1987) suggested that the optimal time for treatment is in the early late mixed dentition, coincident with the eruption of the upper permanent incisors. 2. Skeletal age: Baccetti et al (1998) showed that the early treatment group CVM2 showed effective forward displacement of the maxillary structures whereas the late treatment group CVM3 showed no change compared with controls 3. Chronological age: Other investigators have suggested that for optimal orthopaedic effects, treatment should be initiated before the patient is 9 years old ( Proffit, 2000). 4. Kim et al., 1999, meta-analysis of effectiveness of protraction HG concluded it was less effective on patients >10yrs  Maxillary skeletal protraction, with up to 3mm of forward movement of the maxilla possible , Mandal 2010 and 2012, showed that these effect are stable after 3 years follow-up  McNamara (1987) has described the use of a Biocryl and wire splint  Some recommend using an intraoral bone plate to supportthe PHG force. Systematic review to compare the dentally anchored face mask with skeletally anchored one by Major (2012) in Canada, he found Approximately 3 mm of horizontal A-point movement is predictably attainable with the skeletal one in comparison to dental one..
  • 53. Mohammed Almuzian, University of Glasgow, 2013 52  Many clinicians use protraction with a facemask following or simultaneously with palatal expansion, because some evidence suggests that the expansion makes antero-posterior skeletal change more likely. Kim et al (1999)  There is other evidence that the expansion is optional and should be dictated by the maxillary arch width related to the lower arch width, Vaughan 2005.  Ishii et al (1987) describe the effects of providing the protraction force from the first molars or the premolar region. Protraction from the first molars results in more anterior movement and a forward and upward rotation of the maxilla; protraction from the premolars results in less forward movement but less tendency to upward and forward rotation.  Chin caps, The idea of this appliance is that because the condyle is a growth site, the growth impeded by extra-oral force (Graber, 1977).  Despite success in animal experiments, most human studies have found little difference in mandibular dimensions between treated and untreated subjects (Sugawara et al, 1990).  The effects of chincup therapy , (Thilander 1963)  Reverse chin cup therapy, Developed in Germany in 2012 by Rahman 2012 show similar result when the reverse chin cup therapy compared to face mask therapy in RCT involving 42 samples at age of 8-9 years.  Bone anchored orthopaedic appliance (Bollard miniplates, PFH supported with miniplates) , Success rate 92% with 3mm improvement of maxilla position and zygoma. (Nguyen 2011) (De Clerck 2011)  Shapiro and Kokich 1984 used the same idea by inducing artificial ankylosis and use the ankylosed teeth as anchor.  Reverse twin block, There is no sustained effect on growth of either the maxilla
  • 54. Mohammed Almuzian, University of Glasgow, 2013 53 or mandible. Reverse TB for mandibular prognatisim (Ucem 2004 claim that it producedental effect only)  Extraction of a single lower incisor: If the upper arch is well-aligned but spaceis required to align and retrocline the lower incisors, extraction of a single lower incisor can be an option (Zachrisson 1999) but it may leave some black triangle and gingival recession. This decision depend on the presence of (large IC distance, minor crowding, TSD in LLS, square shape L incisors not triangular).  Sugaya 2012 Cochrane review Two randomized controlled trials were included in this review. There are different types of surgery for this type of malocclusion but only trials of mandible reduction surgery were identified. One trial compared intraoral vertical ramus osteotomy(IVRO) with sagittal split ramus osteotomy (SSRO)and the other trial compared vertical ramus osteotomy(VRO) with and without osteosynthesis. Neither trial found any difference between the two treatments. The trials did not provide adequate data for assessing effectiveness of the techniques described  Cephalometric Yardsticks, Kerr et al 1992 , Stellzig-Eisenhauer et al (2002)