Report Back from SGO: What’s New in Uterine Cancer?.pptx
Best Exit Sites for CVCs Have Low Moisture and Hair
1. Nancy
L.
Moureau,
BSN,
RN,
CRNI,
CPUI,
VA-‐BC
PICC
Excellence,
Inc.
Hartwell,
GA
USA
2. Disclosure
• Nancy
Moureau
• No
conflict
with
this
topic
• Clinician
at
Greenville
Memorial
Hospital
prn
PICC/IV
Team,
30
years
of
vascular
access
experience
• Owner
of
PICC
Excellence,
Inc,
vascular
access
educaGonal
company
18
years
• EducaGonal
provider,
speaker
and
consultant
with
Teleflex,
Cook,
3M,
Excelsior,
Angiodynamics,
STI,
Access
ScienGfic,
Genentech
• Legal
consultant
3. ObjecFves
• IdenGfy
factors
that
increase
risk
of
central
venous
catheter
infecGon
in
relaGon
to
exit
site
• Evaluate
preventaGve
measures
and
how
they
apply
to
the
central
line
bundle
and
site
selecGon
• List
two
ideal
exit
site
locaGons
according
to
stability,
lowest
moisture/hair
and
beQer
dressing
adherence
4. IntroducFon
• InfecGon
is
the
#1
most
serious
complicaGon
for
any
vascular
access
device
• Recent
efforts
worldwide
have
focused
on
prevenGon
and
applicaGon
of
the
central
line
bundle
to
reduce
CVC
infecGons
5. Central
Line
Bundle
PracFces
• Hand
Hygiene
• Site
SelecGon
• Chlorhexidine
disinfecGon
of
skin
• Maximum
barriers
during
inserGon
• Prompt
removal
of
catheter
with
compleGon
of
therapy
CDC, 2011
www.IHI.org
Berenholtz, Crit Care 2004
Pronovost, NEJM 2006
6. Site
SelecFon
Emphasis
• Primary
message:
– Avoid
femoral
– Use
subclavian
over
internal
jugular
– Is
it
the
vein
or
the
locaGon?
– Which
has
lowest
risk?
Risk
on
inserGon
or
risk
of
infecGon???
• Lack
of
substanGal
evidence
to
be
definiGve
for
one
specific
vein
or
veins
as
best;
too
many
variables
Merrer, et al, JAMA 2001
Ruesch, et al Crit Care 2002
Parienti, et al JAMA 2008
7. Pathophysiology
and
Risk
Factors
for
InfecFon
ColonizaGon
of
a
central
venous
catheter
arises
from:
– ContaminaGon
-‐
Failure
to
maintain
asepGc
technique
during
inserGon
or
access
– Skin
flora
-‐
Inadequate
skin
disinfecGon
for
inserGon
and
weekly
dressing
management
– ManipulaGon
or
poor
securement
of
a
catheter
causing
movement
in/out
– Poor
dressing
management,
non-‐adhesive
dressing,
moisture
and
hair
– Bacterial
growth
-‐
Needleless
connectors/ports
that
harbor
bacteria;
poor
disinfecGng.
Residual
blood
in
catheter
or
tubing;
poor
flushing/clearing
– Factors
that
contribute
to
thrombosis
development
and
subsequent
infecGon
8. Commonly
Used
(non
tunneled)
Central
Venous
Catheter
Exit
Sites
– Exit
site
in
the
antecubital
– Exit
site
in
the
supraclavicular
area
area
• Blind
approach
to
PICCs
(w/o
• Blind
approach
to
IJ
(‘lateral’)
US)
or
subclavian
vein
• US
guided
approach
to
IJ,
EJ,
– Exit
site
in
the
upper
mid
subclavian
or
brachiocephalic
arm
(above
the
elbow)
• US
guided
PICCs
(Dawson,
– Exit
site
in
the
infraclavicular
2011)
area
• Blind
approach
to
subclavian
vein
– Exit
site
at
mid
neck
– US
guided
approach
to
• Blind
approach
to
internal/ cephalic
vein
or
axillary
vein
external
jugular
vein
• US
guide
approach
to
IJ
– Exit
site
in
the
groin
– Exit
site
at
base
of
neck
• Blind
or
US
guided
approach
to
the
femoral
vein
or
• US
guide
approach
to
IJ,
saphenous
vein
bracheocephalic
9. Exit
Site
OpFons
#4 Thorax 1X105 Head/Scalp 1X106
Axilla 5X106
#1 ARM 1X102
#3 Abdomen
Groin 2X106 5X104
#2 Thigh 4X104
Ryder, AVA 2011, SHEA 2011
10. Bacterial
DistribuFon
on
Skin
• Number
of
bacterial
• Lower
colonizaGon
• Higher
colonizaGon
cells
on
skin
averages
– Dry
– Moist,
humid
between
10 2-‐108
– Cooler
than
core
– Unable
to
mulG-‐layers
deep
– Flat,
stable
maintain
• Bacterial
density
on
adherence
of
– Minimal
hair
dressing
skin
varies
from
100
colonies/cm2
on
dry
– Hair
follicles
surface,
to
100%
– Sebaceous
glands
increase
in
moist
areas
When catheters are contaminated
Grice, Science 2009
Ruocco, Derm Clin 2007
Li, Hulying, Metagenomics 2011
11. Exit
Site
Risk
• Local
infecGon
and
CRBSI
are
related
to
risk
of
contaminaGon
at
the
exit
site
– Increased
risk
-‐
Moisture,
warmer
areas
of
body,
hair
distribuFon,
failure
of
dressing
to
adhere
– Very
high
risk
-‐
exit
site
at
groin
(moisture
+hair+warm)
– RelaFvely
high
risk
-‐
exit
site
in
the
neck/
chest
area
(moisture+hair;
close
to
oral/
nasal/tracheal
secreGons).
Higher
on
neck
=
higher
risk
(more
hair)
– Low
risk
-‐
exit
site
at
base
of
neck,
on
chest
(dry,
stable),
at
mid
upper
arm
(dry,
stable)
Garnacho-Montero, Int Care Med 2008
Goetz, Inf Cont Hosp Epid 1998
12. Exit
Site
Risk
• Other
non-‐infecGve
complicaGons
(thrombophlebiGs,
venous
thrombosis,
dislodgement,
etc)
– Related
to
stability
of
catheter,
terminal
Gp
posiGon,
vein
vs
catheter
size
– ProblemaGc
securement/dressing
-‐
exit
site
at
mid
neck
or
higher
– Ideal
securement/dressing
maintains
adherence
and
limits
movement
-‐
exit
site
at
upper
mid-‐arm
or
in
the
infraclavicular
area/base
of
neck
13. Best
PosiFon
on
Arm/Thigh/
Abdomen/Chest
• Flat
posiGon
• Low
moisture
• Good
dressing
adherence
• Minimal
hair
14. Effect
of
Dressing
Adherence
• Avoid
– Moisture
and
areas
with
hair,
consider
tunneling
– Ideal
locaGon
on
chest
even
with
IJ,
turn
it
down
onto
chest
15. Issues
with
Femoral/Inguinal
Site
• Moisture
• Hair
• Highest
temperature
• Difficulty
with
dressing
• Consider
tunneling
to
move
exit
locaGon
to
increase
stability,
reduce
moisture
Merrer, et al, JAMA 2001
Goetz, Inf Cont Hosp Epid 1998
Marschall, Inf Cont Hosp Epid 2008
16. PICC
Upper
Arm
vs
Antecubital
• Upper
arm
best
locaGon
– Stable
and
flat,
without
joint
movement
– Dry,
less
hair
– Larger
vein
diameter
– If
inserGon
close
to
axillary
moisture
area
consider
tunneling
– Using
ultrasound
with
upper
arm
placement
Dawson, JAVA 2011
reduces
complicaGons
and
Doellman, JAVA 2009
Falkowski, Nursing 2006
infecGon
Hockley, Crit Care Res
2007
Nichols, JIN 2008
Royer, JIN 2001
Simcock, JAVA 2008
17. Internal
Jugular
with
Chest
Dressing
• InserGon
at
base
of
neck
– Stable
and
flat,
without
movement
– Drier,
less
hair
– Ultrasound
reduces
inserGonal
risk
18. Axillary
Access
as
OpFon
• InserGon
into
axillary
– Stable
and
flat,
without
movement
– Drier,
less
hair
– Less
inserGon
risk
away
from
pleura
– Ultrasound
reduces
inserGonal
risk
19. Risk
ReducFon
Strategies
• Apply
all
5
steps
of
central
line
bundle
• Consider
use
of
anGmicrobial
catheter
and
sponge
dressing,
both
proven
to
reduce
infecGon
• Choose
vein
and
exit
site
independently,
relate
to
risk
• When
moisture/humidity
are
present
at
site
of
vein
access
consider
tunnel
or
alternate
site:
– Axillary
– Upper
arm
– Tunnel
catheter
• Focus
on
securement
and
dressing
adherence
Timsit, 2009 CDC, 2011
Ruschulte, 2008 Maki, 2008
Maki, 2000 HTA UK Assessment, 2008
20. Clinical
ImplicaFons
• Evaluate
central
venous
catheters
with
all
opGons
of
exit
site
using
ultrasound
for
placement
• Consider
zones
or
areas
with
least
risk
of
infecGon
based
on
evidence
• Understand
complicaGons
are
directly
correlated
with
exit
site
related
to
moisture,
temperature
and
dressing
adherence
• Establish
new
terminology
and
classificaGon
of
CVCs
with
focus
on
exit
site
and
risk
reducGon
21. Future
Study
ConsideraFons
• Compare
ultrasound
guided
PICC/
Axillary/Infra
and
Supraclavicular
venous
access
device
with
specific
area
of
inserGon/exit
on
skin.
Evaluate
risk
for
inserGon
and
post
inserGon
complicaGons
• Evaluate
infecGon
rates
for
non-‐
tunneled
catheter
according
to
precise
area
of
exit
site
• Study
each
catheter/vein
complicaGon
rate
based
on
exit
site
(Dawson,
2011)