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Nancy	
  L.	
  Moureau,	
  BSN,	
  RN,	
  CRNI,	
  CPUI,	
  VA-­‐BC	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
                                 PICC	
  Excellence,	
  Inc.	
  
                                  Hartwell,	
  GA	
  USA	
  
Disclosure	
  
•  Nancy	
  Moureau	
  
•  No	
  conflict	
  with	
  this	
  topic	
  	
  
•  Clinician	
  at	
  Greenville	
  Memorial	
  Hospital	
  prn	
  PICC/IV	
  Team,	
  
   30	
  years	
  of	
  vascular	
  access	
  experience	
  
•  Owner	
  of	
  PICC	
  Excellence,	
  Inc,	
  vascular	
  access	
  educaGonal	
  
   company	
  18	
  years	
  
•  EducaGonal	
  provider,	
  speaker	
  and	
  consultant	
  with	
  Teleflex,	
  
   Cook,	
  3M,	
  Excelsior,	
  Angiodynamics,	
  STI,	
  Access	
  ScienGfic,	
  
   Genentech	
  
•  Legal	
  consultant	
  	
  
ObjecFves	
  
•  IdenGfy	
  factors	
  that	
  increase	
  risk	
  of	
  central	
  
   venous	
  catheter	
  infecGon	
  in	
  relaGon	
  to	
  exit	
  
   site	
  
•  Evaluate	
  preventaGve	
  measures	
  and	
  how	
  they	
  
   apply	
  to	
  the	
  central	
  line	
  bundle	
  and	
  site	
  
   selecGon	
  
•  List	
  two	
  ideal	
  exit	
  site	
  locaGons	
  according	
  to	
  
   stability,	
  lowest	
  moisture/hair	
  and	
  beQer	
  
   dressing	
  adherence	
  
IntroducFon	
  
•  InfecGon	
  is	
  the	
  #1	
  most	
  serious	
  complicaGon	
  for	
  any	
  vascular	
  
   access	
  device	
  
•  Recent	
  efforts	
  worldwide	
  have	
  focused	
  on	
  prevenGon	
  and	
  
   applicaGon	
  of	
  the	
  central	
  line	
  bundle	
  to	
  reduce	
  CVC	
  infecGons	
  
Central	
  Line	
  Bundle	
  PracFces
                                          	
  

•  Hand	
  Hygiene	
  
•  Site	
  SelecGon	
  
•  Chlorhexidine	
  disinfecGon	
  of	
  skin	
  
•  Maximum	
  barriers	
  during	
  inserGon	
  
•  Prompt	
  removal	
  of	
  catheter	
  with	
  compleGon	
  
   of	
  therapy	
  
CDC, 2011
www.IHI.org
Berenholtz, Crit Care 2004
Pronovost, NEJM 2006
Site	
  SelecFon	
  Emphasis	
  
•  Primary	
  message:	
  
    –  Avoid	
  femoral	
  
    –  Use	
  subclavian	
  over	
  internal	
  jugular	
  
    –  Is	
  it	
  the	
  vein	
  or	
  the	
  locaGon?	
  
    –  Which	
  has	
  lowest	
  risk?	
  Risk	
  on	
  inserGon	
  or	
  risk	
  of	
  
       infecGon???	
  
•  Lack	
  of	
  substanGal	
  evidence	
  to	
  be	
  definiGve	
  
   for	
  one	
  specific	
  vein	
  or	
  veins	
  as	
  best;	
  too	
  
   many	
  variables	
                        Merrer, et al, JAMA 2001
                                                     Ruesch, et al Crit Care 2002
                                                     Parienti, et al JAMA 2008
Pathophysiology	
  and	
  Risk	
  Factors	
  for	
  
                    InfecFon	
  	
  
ColonizaGon	
  of	
  a	
  central	
  venous	
  catheter	
  arises	
  from:	
  
      –  ContaminaGon	
  -­‐	
  Failure	
  to	
  maintain	
  asepGc	
  technique	
  during	
  inserGon	
  or	
  access	
  
      –  Skin	
  flora	
  -­‐	
  Inadequate	
  skin	
  disinfecGon	
  for	
  inserGon	
  and	
  weekly	
  dressing	
  
         management	
  
      –  ManipulaGon	
  or	
  poor	
  securement	
  of	
  a	
  catheter	
  causing	
  movement	
  in/out	
  
      –  Poor	
  dressing	
  management,	
  non-­‐adhesive	
  dressing,	
  moisture	
  and	
  hair	
  
      –  Bacterial	
  growth	
  -­‐	
  Needleless	
  connectors/ports	
  that	
  harbor	
  bacteria;	
  poor	
  
         disinfecGng.	
  Residual	
  blood	
  in	
  catheter	
  or	
  tubing;	
  poor	
  flushing/clearing	
  
      –  Factors	
  that	
  contribute	
  to	
  thrombosis	
  development	
  and	
  subsequent	
  infecGon	
  
Commonly	
  Used	
  (non	
  tunneled)	
  Central	
  Venous	
  
                                          	
  
                  Catheter	
  Exit	
  Sites
–  Exit	
  site	
  in	
  the	
  antecubital	
            –  Exit	
  site	
  in	
  the	
  supraclavicular	
  
   area	
  	
                                               area	
  
       •  Blind	
  approach	
  to	
  PICCs	
  (w/o	
            •  Blind	
  approach	
  to	
  IJ	
  (‘lateral’)	
  
          US)	
                                                    or	
  subclavian	
  vein	
  
                                                                •  US	
  guided	
  approach	
  to	
  IJ,	
  EJ,	
  
–  Exit	
  site	
  in	
  the	
  upper	
  mid	
                     subclavian	
  or	
  brachiocephalic	
  	
  
   arm	
  (above	
  the	
  elbow)	
  	
  
       •  US	
  guided	
  PICCs	
  (Dawson,	
  
                                                         –  Exit	
  site	
  in	
  the	
  infraclavicular	
  
          2011)	
                                           area	
  
                                                                •  Blind	
  approach	
  to	
  subclavian	
  
                                                                   vein	
  
–  Exit	
  site	
  at	
  mid	
  neck	
  
                                                         –  US	
  guided	
  approach	
  to	
  
       •  Blind	
  approach	
  to	
  internal/              cephalic	
  vein	
  or	
  axillary	
  vein	
  
          external	
  jugular	
  vein	
  
       •  US	
  guide	
  approach	
  to	
  IJ	
          –  Exit	
  site	
  in	
  the	
  groin	
  
–  Exit	
  site	
  at	
  base	
  of	
  neck	
                   •  Blind	
  or	
  US	
  guided	
  approach	
  
                                                                   to	
  the	
  femoral	
  vein	
  or	
  
       •  US	
  guide	
  approach	
  to	
  IJ,	
                   saphenous	
  vein	
  
          bracheocephalic	
  
Exit	
  Site	
  OpFons
                                            	
  
   #4 Thorax 1X105        Head/Scalp 1X106
Axilla 5X106




#1 ARM 1X102


                     #3 Abdomen
Groin   2X106        5X104


#2 Thigh 4X104
                             Ryder, AVA 2011, SHEA 2011
Bacterial	
  DistribuFon	
  on	
  Skin	
  
•  Number	
  of	
  bacterial	
   •  Lower	
  colonizaGon	
   •  Higher	
  colonizaGon	
  
   cells	
  on	
  skin	
  averages	
   –  Dry	
                      –  Moist,	
  humid	
  
   between	
  10      2-­‐108	
  
                                       –  Cooler	
  than	
  core	
   –  Unable	
  to	
  
   mulG-­‐layers	
  deep	
             –  Flat,	
  stable	
             maintain	
  
•  Bacterial	
  density	
  on	
                                         adherence	
  of	
  
                                       –  Minimal	
  hair	
             dressing	
  
   skin	
  varies	
  from	
  100	
  
   colonies/cm2	
  on	
  dry	
                                       –  Hair	
  follicles	
  
   surface,	
  to	
  100%	
                                          –  Sebaceous	
  glands	
  
   increase	
  in	
  moist	
  
   areas	
  




  When catheters are contaminated
                                                            Grice, Science 2009
                                                            Ruocco, Derm Clin 2007
                                                            Li, Hulying, Metagenomics 2011
Exit	
  Site	
  Risk	
  
•  Local	
  infecGon	
  and	
  CRBSI	
  are	
  related	
  to	
  
   risk	
  of	
  contaminaGon	
  at	
  the	
  exit	
  site	
  
     –  Increased	
  risk	
  -­‐	
  Moisture,	
  warmer	
  areas	
  
        of	
  body,	
  hair	
  distribuFon,	
  failure	
  of	
  
        dressing	
  to	
  adhere	
  
     –  Very	
  high	
  risk	
  -­‐	
  exit	
  site	
  at	
  groin	
  (moisture
        +hair+warm)	
  
     –  RelaFvely	
  high	
  risk	
  -­‐	
  exit	
  site	
  in	
  the	
  neck/
        chest	
  area	
  (moisture+hair;	
  close	
  to	
  oral/
        nasal/tracheal	
  secreGons).	
                                	
  	
  	
  	
  	
  
        Higher	
  on	
  neck	
  =	
  higher	
  risk	
  (more	
  hair)	
  
     –  Low	
  risk	
  -­‐	
  exit	
  site	
  at	
  base	
  of	
  neck,	
  on	
  
        chest	
  (dry,	
  stable),	
  at	
  mid	
  upper	
  arm	
  (dry,	
  
        stable)	
  
Garnacho-Montero, Int Care Med 2008
Goetz, Inf Cont Hosp Epid 1998
Exit	
  Site	
  Risk	
  
•  Other	
  non-­‐infecGve	
  complicaGons	
  
  (thrombophlebiGs,	
  venous	
  thrombosis,	
  
  dislodgement,	
  etc)	
  	
  
   –  Related	
  to	
  stability	
  of	
  catheter,	
  terminal	
  Gp	
  
      posiGon,	
  vein	
  vs	
  catheter	
  size	
  	
  
   –  ProblemaGc	
  securement/dressing	
  -­‐	
  exit	
  site	
  at	
  mid	
  
      neck	
  or	
  higher	
  
   –  Ideal	
  securement/dressing	
  maintains	
  adherence	
  
      and	
  limits	
  movement	
  -­‐	
  exit	
  site	
  at	
  upper	
  mid-­‐arm	
  
      or	
  in	
  the	
  infraclavicular	
  area/base	
  of	
  neck	
  
Best	
  PosiFon	
  on	
  Arm/Thigh/
                 Abdomen/Chest       	
  
•  Flat	
  posiGon	
  
•  Low	
  moisture	
  
•  Good	
  dressing	
  
   adherence	
  
•  Minimal	
  hair	
  
Effect	
  of	
  Dressing	
  Adherence	
  
•  Avoid	
  
   –  Moisture	
  and	
  areas	
  with	
  hair,	
  
      consider	
  tunneling	
  
   –  Ideal	
  locaGon	
  on	
  chest	
  even	
  
      with	
  IJ,	
  turn	
  it	
  down	
  onto	
  chest	
  
Issues	
  with	
  Femoral/Inguinal	
  Site	
  
•  Moisture	
  
•  Hair	
  
•  Highest	
  
   temperature	
  
•  Difficulty	
  with	
  
   dressing	
  
•  Consider	
  tunneling	
  
   to	
  move	
  exit	
  
   locaGon	
  to	
  increase	
  
   stability,	
  reduce	
  
   moisture	
  
                      Merrer, et al, JAMA 2001
                      Goetz, Inf Cont Hosp Epid 1998
                      Marschall, Inf Cont Hosp Epid 2008
PICC	
  Upper	
  Arm	
  vs	
  Antecubital
                                            	
  
•  Upper	
  arm	
  best	
  locaGon	
  
    –  Stable	
  and	
  flat,	
  without	
  
       joint	
  movement	
  
    –  Dry,	
  less	
  hair	
  
    –  Larger	
  vein	
  diameter	
  
    –  If	
  inserGon	
  close	
  to	
  axillary	
  
       moisture	
  area	
  consider	
  
       tunneling	
  
    –  Using	
  ultrasound	
  with	
  
       upper	
  arm	
  placement	
                     Dawson, JAVA 2011
       reduces	
  complicaGons	
  and	
                Doellman, JAVA 2009
                                                       Falkowski, Nursing 2006
       infecGon	
                                      Hockley, Crit Care Res
                                                       2007
                                                       Nichols, JIN 2008
                                                       Royer, JIN 2001
                                                       Simcock, JAVA 2008
Internal	
  Jugular	
  with	
  Chest	
  
                     Dressing   	
  
•  InserGon	
  at	
  base	
  of	
  neck	
  
    –  Stable	
  and	
  flat,	
  without	
  
       movement	
  
    –  Drier,	
  less	
  hair	
  
    –  Ultrasound	
  reduces	
  
       inserGonal	
  risk	
  
Axillary	
  Access	
  as	
  OpFon	
  

•  InserGon	
  into	
  axillary	
  
    –  Stable	
  and	
  flat,	
  without	
  
       movement	
  
    –  Drier,	
  less	
  hair	
  
    –  Less	
  inserGon	
  risk	
  away	
  
       from	
  pleura	
  
    –  Ultrasound	
  reduces	
  
       inserGonal	
  risk	
  
Risk	
  ReducFon	
  Strategies
                                        	
  
•  Apply	
  all	
  5	
  steps	
  of	
  central	
  line	
  bundle	
  
•  Consider	
  use	
  of	
  anGmicrobial	
  catheter	
  and	
  sponge	
  
   dressing,	
  both	
  proven	
  to	
  reduce	
  infecGon	
  
•  Choose	
  vein	
  and	
  exit	
  site	
  independently,	
  relate	
  to	
  risk	
  
•  When	
  moisture/humidity	
  are	
  present	
  at	
  site	
  of	
  vein	
  
   access	
  consider	
  tunnel	
  or	
  alternate	
  site:	
  	
  
    –  Axillary	
  
    –  Upper	
  arm	
  	
  
    –  Tunnel	
  catheter	
  
•  Focus	
  on	
  securement	
  and	
  dressing	
  adherence	
  
                                                Timsit, 2009        CDC, 2011
                                                Ruschulte, 2008     Maki, 2008
                                                Maki, 2000          HTA UK Assessment, 2008
Clinical	
  ImplicaFons	
  
•  Evaluate	
  central	
  venous	
  catheters	
  with	
  all	
  opGons   	
  
   of	
  exit	
  site	
  using	
  ultrasound	
  for	
  placement	
  	
  
•  Consider	
  zones	
  or	
  areas	
  with	
  least	
  risk	
  of	
  
   infecGon	
  based	
  on	
  evidence	
  
•  Understand	
  complicaGons	
  are	
  directly	
  correlated	
  
   with	
  exit	
  site	
  related	
  to	
  moisture,	
  temperature	
  
   and	
  dressing	
  adherence	
  
•  Establish	
  new	
  terminology	
  and	
  classificaGon	
  of	
  
   CVCs	
  with	
  focus	
  on	
  exit	
  site	
  and	
  risk	
  reducGon	
  
Future	
  Study	
  ConsideraFons
                                       	
  
•  Compare	
  ultrasound	
  guided	
  PICC/
   Axillary/Infra	
  and	
  Supraclavicular	
  
   venous	
  access	
  device	
  with	
  specific	
  area	
  
   of	
  inserGon/exit	
  on	
  skin.	
  Evaluate	
  risk	
  
   for	
  inserGon	
  and	
  post	
  inserGon	
  
   complicaGons	
  
•  Evaluate	
  infecGon	
  rates	
  for	
  non-­‐
   tunneled	
  catheter	
  according	
  to	
  precise	
  
   area	
  of	
  exit	
  site	
  
•  Study	
  each	
  catheter/vein	
  complicaGon	
  
   rate	
  based	
  on	
  exit	
  site	
  (Dawson,	
  2011)	
  
QUESTIONS?	
  

                     Speaker	
  Contact	
  InformaGon:	
  
                         Nancy	
  Moureau	
  
                         Email:	
  nancy@piccexcellence.com	
  
                         Website	
  informaGon:	
  
                         www.piccexcellence.com	
  

THANK	
  YOU!!	
  

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Best Exit Sites for CVCs Have Low Moisture and Hair

  • 1. Nancy  L.  Moureau,  BSN,  RN,  CRNI,  CPUI,  VA-­‐BC                           PICC  Excellence,  Inc.   Hartwell,  GA  USA  
  • 2. Disclosure   •  Nancy  Moureau   •  No  conflict  with  this  topic     •  Clinician  at  Greenville  Memorial  Hospital  prn  PICC/IV  Team,   30  years  of  vascular  access  experience   •  Owner  of  PICC  Excellence,  Inc,  vascular  access  educaGonal   company  18  years   •  EducaGonal  provider,  speaker  and  consultant  with  Teleflex,   Cook,  3M,  Excelsior,  Angiodynamics,  STI,  Access  ScienGfic,   Genentech   •  Legal  consultant    
  • 3. ObjecFves   •  IdenGfy  factors  that  increase  risk  of  central   venous  catheter  infecGon  in  relaGon  to  exit   site   •  Evaluate  preventaGve  measures  and  how  they   apply  to  the  central  line  bundle  and  site   selecGon   •  List  two  ideal  exit  site  locaGons  according  to   stability,  lowest  moisture/hair  and  beQer   dressing  adherence  
  • 4. IntroducFon   •  InfecGon  is  the  #1  most  serious  complicaGon  for  any  vascular   access  device   •  Recent  efforts  worldwide  have  focused  on  prevenGon  and   applicaGon  of  the  central  line  bundle  to  reduce  CVC  infecGons  
  • 5. Central  Line  Bundle  PracFces   •  Hand  Hygiene   •  Site  SelecGon   •  Chlorhexidine  disinfecGon  of  skin   •  Maximum  barriers  during  inserGon   •  Prompt  removal  of  catheter  with  compleGon   of  therapy   CDC, 2011 www.IHI.org Berenholtz, Crit Care 2004 Pronovost, NEJM 2006
  • 6. Site  SelecFon  Emphasis   •  Primary  message:   –  Avoid  femoral   –  Use  subclavian  over  internal  jugular   –  Is  it  the  vein  or  the  locaGon?   –  Which  has  lowest  risk?  Risk  on  inserGon  or  risk  of   infecGon???   •  Lack  of  substanGal  evidence  to  be  definiGve   for  one  specific  vein  or  veins  as  best;  too   many  variables   Merrer, et al, JAMA 2001 Ruesch, et al Crit Care 2002 Parienti, et al JAMA 2008
  • 7. Pathophysiology  and  Risk  Factors  for   InfecFon     ColonizaGon  of  a  central  venous  catheter  arises  from:   –  ContaminaGon  -­‐  Failure  to  maintain  asepGc  technique  during  inserGon  or  access   –  Skin  flora  -­‐  Inadequate  skin  disinfecGon  for  inserGon  and  weekly  dressing   management   –  ManipulaGon  or  poor  securement  of  a  catheter  causing  movement  in/out   –  Poor  dressing  management,  non-­‐adhesive  dressing,  moisture  and  hair   –  Bacterial  growth  -­‐  Needleless  connectors/ports  that  harbor  bacteria;  poor   disinfecGng.  Residual  blood  in  catheter  or  tubing;  poor  flushing/clearing   –  Factors  that  contribute  to  thrombosis  development  and  subsequent  infecGon  
  • 8. Commonly  Used  (non  tunneled)  Central  Venous     Catheter  Exit  Sites –  Exit  site  in  the  antecubital   –  Exit  site  in  the  supraclavicular   area     area   •  Blind  approach  to  PICCs  (w/o   •  Blind  approach  to  IJ  (‘lateral’)   US)   or  subclavian  vein   •  US  guided  approach  to  IJ,  EJ,   –  Exit  site  in  the  upper  mid   subclavian  or  brachiocephalic     arm  (above  the  elbow)     •  US  guided  PICCs  (Dawson,   –  Exit  site  in  the  infraclavicular   2011)   area   •  Blind  approach  to  subclavian   vein   –  Exit  site  at  mid  neck   –  US  guided  approach  to   •  Blind  approach  to  internal/ cephalic  vein  or  axillary  vein   external  jugular  vein   •  US  guide  approach  to  IJ   –  Exit  site  in  the  groin   –  Exit  site  at  base  of  neck   •  Blind  or  US  guided  approach   to  the  femoral  vein  or   •  US  guide  approach  to  IJ,   saphenous  vein   bracheocephalic  
  • 9. Exit  Site  OpFons   #4 Thorax 1X105 Head/Scalp 1X106 Axilla 5X106 #1 ARM 1X102 #3 Abdomen Groin 2X106 5X104 #2 Thigh 4X104 Ryder, AVA 2011, SHEA 2011
  • 10. Bacterial  DistribuFon  on  Skin   •  Number  of  bacterial   •  Lower  colonizaGon   •  Higher  colonizaGon   cells  on  skin  averages   –  Dry   –  Moist,  humid   between  10 2-­‐108   –  Cooler  than  core   –  Unable  to   mulG-­‐layers  deep   –  Flat,  stable   maintain   •  Bacterial  density  on   adherence  of   –  Minimal  hair   dressing   skin  varies  from  100   colonies/cm2  on  dry   –  Hair  follicles   surface,  to  100%   –  Sebaceous  glands   increase  in  moist   areas   When catheters are contaminated Grice, Science 2009 Ruocco, Derm Clin 2007 Li, Hulying, Metagenomics 2011
  • 11. Exit  Site  Risk   •  Local  infecGon  and  CRBSI  are  related  to   risk  of  contaminaGon  at  the  exit  site   –  Increased  risk  -­‐  Moisture,  warmer  areas   of  body,  hair  distribuFon,  failure  of   dressing  to  adhere   –  Very  high  risk  -­‐  exit  site  at  groin  (moisture +hair+warm)   –  RelaFvely  high  risk  -­‐  exit  site  in  the  neck/ chest  area  (moisture+hair;  close  to  oral/ nasal/tracheal  secreGons).             Higher  on  neck  =  higher  risk  (more  hair)   –  Low  risk  -­‐  exit  site  at  base  of  neck,  on   chest  (dry,  stable),  at  mid  upper  arm  (dry,   stable)   Garnacho-Montero, Int Care Med 2008 Goetz, Inf Cont Hosp Epid 1998
  • 12. Exit  Site  Risk   •  Other  non-­‐infecGve  complicaGons   (thrombophlebiGs,  venous  thrombosis,   dislodgement,  etc)     –  Related  to  stability  of  catheter,  terminal  Gp   posiGon,  vein  vs  catheter  size     –  ProblemaGc  securement/dressing  -­‐  exit  site  at  mid   neck  or  higher   –  Ideal  securement/dressing  maintains  adherence   and  limits  movement  -­‐  exit  site  at  upper  mid-­‐arm   or  in  the  infraclavicular  area/base  of  neck  
  • 13. Best  PosiFon  on  Arm/Thigh/ Abdomen/Chest   •  Flat  posiGon   •  Low  moisture   •  Good  dressing   adherence   •  Minimal  hair  
  • 14. Effect  of  Dressing  Adherence   •  Avoid   –  Moisture  and  areas  with  hair,   consider  tunneling   –  Ideal  locaGon  on  chest  even   with  IJ,  turn  it  down  onto  chest  
  • 15. Issues  with  Femoral/Inguinal  Site   •  Moisture   •  Hair   •  Highest   temperature   •  Difficulty  with   dressing   •  Consider  tunneling   to  move  exit   locaGon  to  increase   stability,  reduce   moisture   Merrer, et al, JAMA 2001 Goetz, Inf Cont Hosp Epid 1998 Marschall, Inf Cont Hosp Epid 2008
  • 16. PICC  Upper  Arm  vs  Antecubital   •  Upper  arm  best  locaGon   –  Stable  and  flat,  without   joint  movement   –  Dry,  less  hair   –  Larger  vein  diameter   –  If  inserGon  close  to  axillary   moisture  area  consider   tunneling   –  Using  ultrasound  with   upper  arm  placement   Dawson, JAVA 2011 reduces  complicaGons  and   Doellman, JAVA 2009 Falkowski, Nursing 2006 infecGon   Hockley, Crit Care Res 2007 Nichols, JIN 2008 Royer, JIN 2001 Simcock, JAVA 2008
  • 17. Internal  Jugular  with  Chest   Dressing   •  InserGon  at  base  of  neck   –  Stable  and  flat,  without   movement   –  Drier,  less  hair   –  Ultrasound  reduces   inserGonal  risk  
  • 18. Axillary  Access  as  OpFon   •  InserGon  into  axillary   –  Stable  and  flat,  without   movement   –  Drier,  less  hair   –  Less  inserGon  risk  away   from  pleura   –  Ultrasound  reduces   inserGonal  risk  
  • 19. Risk  ReducFon  Strategies   •  Apply  all  5  steps  of  central  line  bundle   •  Consider  use  of  anGmicrobial  catheter  and  sponge   dressing,  both  proven  to  reduce  infecGon   •  Choose  vein  and  exit  site  independently,  relate  to  risk   •  When  moisture/humidity  are  present  at  site  of  vein   access  consider  tunnel  or  alternate  site:     –  Axillary   –  Upper  arm     –  Tunnel  catheter   •  Focus  on  securement  and  dressing  adherence   Timsit, 2009 CDC, 2011 Ruschulte, 2008 Maki, 2008 Maki, 2000 HTA UK Assessment, 2008
  • 20. Clinical  ImplicaFons   •  Evaluate  central  venous  catheters  with  all  opGons   of  exit  site  using  ultrasound  for  placement     •  Consider  zones  or  areas  with  least  risk  of   infecGon  based  on  evidence   •  Understand  complicaGons  are  directly  correlated   with  exit  site  related  to  moisture,  temperature   and  dressing  adherence   •  Establish  new  terminology  and  classificaGon  of   CVCs  with  focus  on  exit  site  and  risk  reducGon  
  • 21. Future  Study  ConsideraFons   •  Compare  ultrasound  guided  PICC/ Axillary/Infra  and  Supraclavicular   venous  access  device  with  specific  area   of  inserGon/exit  on  skin.  Evaluate  risk   for  inserGon  and  post  inserGon   complicaGons   •  Evaluate  infecGon  rates  for  non-­‐ tunneled  catheter  according  to  precise   area  of  exit  site   •  Study  each  catheter/vein  complicaGon   rate  based  on  exit  site  (Dawson,  2011)  
  • 22. QUESTIONS?   Speaker  Contact  InformaGon:   Nancy  Moureau   Email:  nancy@piccexcellence.com   Website  informaGon:   www.piccexcellence.com   THANK  YOU!!