1. VAMSI KUMAR.A, Dep No (17-PML-014)

2. INTRODUCTION
1. Classification
2. Arboviruses prevalent
in India
3. Epidemiology
4. General Properties
5. Stucture of Virus
6. Modes of transmission
7. Pathogensis
8. Clinical symptoms
9. Lab Diagnosis
10. Treatment
11. Prophylaxis

3. All are RNA viruses

5. •Arbovirus is a term used to refer to any
viruses that is transmitted by arthropod
vectors. The word arbovirus is an
acronym (ARthropod-BOrne virus).

9. ZIKA recent celebrity virus........

10. HISTORY
1800s Dengue fever epidemics occur globally
1898-1914 First large scale effort to prevent arbovirus infection
 takes place in Florida, Havana, and the Panama Canal Zone
1901 First arbovirus, the yellow fever virus, is discovered
1906 Dengue fever transmission is discovered
1936 Tick-borne encephalitis virus is discovered
1937 Yellow fever vaccine is invented
1937 West Nile virus is discovered
1950s Japanese encephalitis vaccines are invented
1980s Insecticide treated mosquito nets are developed
1999 West Nile virus reaches the Western Hemisphere
Late 1900s Dengue fever spreads globally

13. CONFUSED...?

14. The main genera for arboviruses that cause infections in humans are as follows:

15. Referer C.P baveja........

17. Arboviruses prevalent in India

18. GENERAL PROPERTIES
• 1. All members produce fatal in suckling mice after
• intracerebral inoculation
• 2. They possess and agglutinate erythrocytes of goose
• or day-old chicks
• 3. They can be grown in tissue cultures of primary cells like chick
• embryo fibroblasts or continuous cell lines like vero, and in cultures
• of appropriate insect tissues
• 4. They may also be isolated in the or of chick embryo
• 5. In general, arboviruses are readily inactivated at room temperature
• and by bile salts, ether and other lipid solvents

19. 1.Encephalitis
2.Febrile illness Definition. From the Latin word febris, meaning fever, an acute febrile
illness is a type of illness characterized by a sudden onset of fever, which is an increase in
internal body temperature to levels above normal. symptoms include headache, chills or
muscle ach.
3.hemorrhagic fevers

20. Referer C.P baveja........

24. 1. The virus is transmitted by Aedes aegypti
2. Full-blown disease is most common in adults
3. Incubation period - 2-3 days
4. The disease is chracterised by fever, crippling joint pains,
5. lymphadenopathy, conjunctivitis and rash
6. Migratory polyarthritis mainly affects the small joints of the hands
7. and wrists
8. The fever is typically biphasic with a period of remission after
9. 1-6 days
10. A maculopapular rash is common and most intense on the trunk
11. and limbs that may desquamate
12. Haemorrhagic manifestations are seen in some patients
13. Chickungunya is the native word for the disease in which the
14. patient lies ‘doubled up’ due to severe joint pains
15. The virus first appeared in India in 1963 when it caused extensive
16. epidemics in calcutta, Madras and other areas
17. There is no animal reservoir for the virus
18. No vaccine is available

27. DIAGNOSIS
• Preliminary diagnosis of arbovirus infection is usually based
on clinical presentations of symptoms, places and dates of
travel, activities, and epidemiological history of the location
where infection occurred.[47] Definitive diagnosis is typically
made in a laboratory by employing some combination of
• blood tests, particularly , and/or
virologic techniques such as ,[47][48]
,[48] ,[48][49]
n ,[50] and
.[51]

30. DENGUE...........