2. SWEAT TEST
-used to diagnose Cystic Fibrosis
Mucoviscidosis
-autosomal recessive metabolic disorder affecting the mucous secreting
glands of the body
-associated with pancreatic insufficiency, respiratory distress and
intestinal obstruction
-Increase sodium and chloride due to inability of the sweat glands to
reabsorb them before the sweat is secreted
3. GIBSON AND COOKE PILOCARPINE IONTOPHORESIS
Pilocarpine + mild current= induce sweat production
Sodium: Flame photometry, Ion exchange electrode
Chloride: Manual or automated titration
SWEAT Sodium and Chloride values:
>70 mEq/L= diagnostic for CF
40 mEq/L= Borderline for CF
