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RHEUMATOID ARTHRITIS (RA).pptx

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RHEUMATOID ARTHRITIS (RA).pptx

  1. 1. Dr shweta suryavanshi-
  2. 2.  RA is a non suppurative, systemic, inflammatory disease of unknown cause characterized by polyarthritis of symmetrical joints and involving the peripheral joints and extra articular surface
  3. 3.  Gender :F>M; 3:1  Age: 35-55 – years
  4. 4.  Idiopathic  Abnormal immunological reaction  Antigenic agents, which probably act as predisposing factors, are viruses: rubella, Epstein-Barr, etc. genetic (common in people with HLA DR4 60%), psychological stress, allergic factors, endocrine factors and metabolic factors.
  5. 5.  Genetic factor  Seasonal factor  Overstrain  Emotional disturbance  Malnutrition  Vitamin D deficiency  Jaundice  Pregnancy
  6. 6.  Diet,  Psychosomatic disorders,  Trauma,  Endocrine dysfunction,  Hereditary influences,  Infection
  7. 7.  3 Stages- 1. Synovitis 2. Destruction 3. Deformity
  8. 8. Vascular congestion Infiltration of synovial layer Persistent inflammation Destruction of joints and tendons
  9. 9. Erosion of articular cartilage Osteoporotic changes Joint subluxation and deformity a
  10. 10.  Stage I. Inflammation of the synovial membrane spreads to articular cartilage and other soft tissues. There occurs limitation of joint movements with pain and muscle spasm.  Stage II. Granulation tissue formation occurs within the synovial membrane and spreads to the periarticular tissues. The cartilage starts disintegrating and the joint is filled with granulation tissue. There occurs thickening of the joint capsule, tendons and their sheaths impairing the joint movement permanently
  11. 11.  Stage III. The granulation tissue  fibrous tissue  adhesion formation between the tendons, joint capsule and the articular surfaces. The articular surfaces get partly covered by cartilage and partly by fibrous tissue gives rise to contractures and even ankylosis of the joint, or secondary osteoarthritis.
  12. 12. According to the American College of Rheumatology in 1987 revised criteria, at least 4 out of 7 criteria should be fulfilled to make a diagnosis of rheumatoid arthritis.  • Morning stiffness for minimum one hour everyday, at least for six weeks.  • Arthritis or swelling of three or more joints for > 6 weeks.  • Arthritis or swelling of hand joints (wrist, metacarpal) for more than 6 weeks.  • Symmetrical swelling (arthritis of same joint areas) more than 6 weeks.  • Serum rheumatoid factor present.  • Radiographic features of RA.  • Rheumatoid nodules.
  13. 13.  Acute stage –  Joint pain  Swelling  Early morning stiffness  Loss of movements if small joints affected  Tenderness  Warmth and stiffness if large joints affected
  14. 14.  Chronic stage  Joint deformities  Dislocation of small joints (if affected)  Restricted ROM  Pain and stiffness in cervical spine(if affected)  ADL affected
  15. 15.  Sub cutaneous nodules  Muscle wasting  Lungs – pleural effusion, bronchitis  Heart – pericarditis, endocarditis and myocardial diseases  Neuropathies – mononeuritis multiplex  Mouth – dryness of mouth  Kidney and spleen can also be affected
  16. 16.  Subjective –  Chief complaints: • Pain in bilateral joints • Morning stiffness • Unable to do movements freely • Difficulty in daily activities • May complain of neck pain
  17. 17.  Pain assessment: • Onset – Gradual • Site – body chart, UL more common than LL, peripheral joints> vertebral joints • Severity – VAS • Nature – constant, dull aching or sharp • Aggravating Factors – movements, cold climate, pressure of clothes • Relieving Factors – sometimes at rest
  18. 18.  Level of pain 1. Pain after specific activities 2. Pain during and after activities but it doesn't affect performance 3. Pain affects performance 4. Pain present in ADL 5. Constant dull aching pain without disturbing sleep 6. Pain disturbing sleep
  19. 19.  On Observation  Deformities – • Hand – boutonniere deformity( Flexed PIP, Extended DIP), Swan neck deformity(PIP hyperextended, DIP flexion) • Wrist – flexion deformity • Elbow – flexion deformity • Knees – flexion, valgus, wind swept deformity, Baker’s cyst – popliteal fossa
  20. 20. • Feets – lateral deviation of toes, MT heads prominent on plantar aspect, hallux valgus, bunion, pes cavus, claw toes  External appliances – assistive devices, splints can be present  Skin – papery, shiny and thin
  21. 21.  On Palpation –  Warmth – may or may not be present  Tenderness – can be present  Effusion – can be present in large joints  Swelling – will be present
  22. 22.  On examination –  Deformities – will be present, check whether it is fixed or correctable by passive methods  ROM – will be restricted  Limb length – may or may not be affected  Gait analysis – will be affected – limping gait/ antalgic gait can be present
  23. 23.  Investigations  Blood culture • ESR – increased • Serum albumin – decreased • Globulin – increased • Platelets – increased • WBC – increased • Rheumatoid factor - positive
  24. 24.  Synovial fluid examination – • Yellow, watery, turbid • Low sugar • WBC- increased
  25. 25.  Radiographs • To rule out deformities • Atlanto axial subluxation can be seen in cervical spine
  26. 26.  Tendon rupture  Cord compression  Osteoporosis  C1-c2 subluxation - quadriparesis
  27. 27.  Classification of Functional Capacity for RA 1. Complete functional capacity with ability to carry on all normal duties 2. Functional capacity adequate to conduct normal activities despite of discomfort or limited mobility of one or more joints 3. Functional capacity adequate to perform only a few or none of the duties of usual occupation or self care
  28. 28. 4. Largely or wholly in capitated. Patient will be bed ridden or confined to wheel chair, permitting little or no self care
  29. 29.  Criteria for diagnosis of RA- any 4 or more symptoms should be present 1. Early morning stiffness 2. Involvement of more than 3 joints 3. Symmetrical involvement 4. Subcutaneous nodules 5. RH factor positive 6. X ray of hand and wrist involved for 6 weeks or more
  30. 30.  Home programme  Follow up
  31. 31.  Rest  Continuous Splinting  NSAIDS  Immunosuppressive Drugs  Local Injection
  32. 32.  Aims-  To relieve pain and muscle spasm  To decrease the acute inflammation  To improve muscle strength  To train patient for independent ambulation  To increase endurance  To prevent and correct deformity  To maintain and improve muscle tone  To improve respiratory and circulatory conditions  To improve ADL
  33. 33.  Means- 1. Acute inflammation  Rest  Joint protection – splinting, assistive device, ambulatory aids  Relaxation
  34. 34. 2. Pain  Physical modalities – moist pack/cryotherapy, TENS/IFT 3. ROM  PROM exercises, AROM exs, Stretching 4. For muscle weakness  Strengthening – isometric, isotonic, isokinetic
  35. 35. 5. Ambulation  Ambulatory aids  Orthosis  Gait training 6. To increase endurance  Energy conservation techniques  Aerobic exercise program 7. Difficulty in ADL  Adaptive equipments  Assistive devices
  36. 36. 8. Deformity correction  Passive stretching  Splinting  Serial stretching (POP)  Traction
  37. 37.  Acute or active phase of the disease the acute symptoms - pain, erythema, tenderness and swelling - are present.  1. Positioning - of the involved joints and correct bed posture.  Firm mattress or occasional back support minimizes the effects of malpositioning and preserves the integrity of the affected joints.  The limb is positioned in level of minimal discomfort.  Contracture Prone positions should be avoided.
  38. 38.  2. Splints and sand bags  provide additional support to the limb.  Special attention is needed for the knee and elbow joints  prone to develop flexion contractures.  The use of casts  minimum. The splints or the casts should be checked regularly to avoid complications.
  39. 39.  3. Deep breathing exercises  to improve the vital capacity.  4. The joints and muscles free from immobilization and the active disease  full ROM and progressive resistive exercise (PRE).  5. The functional mobility should be encouraged and maintained.
  40. 40.  6. Postural guidance and the methods of performing activities without putting extra- strain on the affected joints are taught.  7. In cases with involvement of the weight bearing joints the upper extremities should be prepared for future crutch walking.
  41. 41.  8.Isometrics: Isometric exercises do not involve the movements of the joints and are therefore relatively painless.  Should be started early.  The muscles like quadriceps and deltoid are susceptible to disuse atrophy and hence need repeated sessions of isometrics.  The other functional muscles concerned with weight bearing and body balance need strengthening and improved endurance.
  42. 42.  9. Speedy isometrics to the affected limb in elevation reduce swelling and effusion (especially of the knee).  10.No heat therapy should be given to the joints which are already warm.  11.TENS, pulsed ultrasound for longer periods offer reduction in the muscle spasm and pain.
  43. 43.  13.Properly guided pool therapy for the whole body provides an ideal medium for exercises.
  44. 44.  14. Splinting  WHO  Splinting should be given in functional position of hand – 5-10 degrees of wrist flexion, 10-20 degrees of MCP flexion and 10-15 degrees of PIP flexion  For swan neck deformity – double ring flexion splint  For boutonniere deformity – double ring extension splint
  45. 45.  Wax therapy – – relieves morning stiffness  HWF – 5-10 mins  Correction of deformity  Patient education by joint protection and energy conservation techniques  Four Ps 1. Pacing 2. Priority 3. Planning 4. Positioning
  46. 46.  It is a phase of vigorous activity to train the patient to use the involved joints to the greatest extent for physical independence.  By 4-5 weeks of the onset independent sitting by the use of hands can be started.  If pain permits, active and functional therapeutic programs should be initiated include standing and walking.  weight bearing should be deferred till pain and discomfort subside
  47. 47.  Before allowing weight bearing it is absolutely essential to provide the necessary orthotic support or walking aid to relieve compressive forces on the affected joints.  This should be done between the parallel bars to judge the effects of weight bearing on the diseased joints.  Sustained or intermittent stretching  for muscles which have developed tightness or contractures during the acute phase.  Deep heat , ultrasound, TENS and other adjuncts may be used to relieve pain.
  48. 48.  Efforts should be made to improve the strength and endurance of the muscles related to the affected joints.  Job-oriented performance to be imparted in the exercise regime.  Relapse  Relapse is common RA. It should be treated on the same lines as detailed for the acute phase.  Usual sites of contractures and their prevention  Since it is a systemic disease, it is usually accompanied by early fatigue. Therefore, exercise sessions should be brief.
  49. 49.  The prognosis of the disease is very much unpredictable. There may be:  (a) Partial or total remission;  (b) Remaining as a mild disease;  (c) Insidious progressive in nature;  (d) Progressive, but the progress of the disease may be (i) rapid (ii) slow or (iii) intermediate.
  50. 50.  Synovectomy  Soft tissue release  Osteotomy  Arthroplasty  Arthrodesis  Tendon repair or transfer

Notas do Editor

  • Wind swept – one knee in severe valgus and another in severe valgus

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