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Dr shweta suryavanshi-
 RA is a non suppurative, systemic,
inflammatory disease of unknown cause
characterized by polyarthritis of symmetrical
joints and involving the peripheral joints and
extra articular surface
 Gender :F>M; 3:1
 Age: 35-55 – years
 Idiopathic
 Abnormal immunological reaction
 Antigenic agents, which probably act as
predisposing factors, are viruses: rubella,
Epstein-Barr, etc. genetic (common in people
with HLA DR4 60%), psychological stress,
allergic factors, endocrine factors and
metabolic factors.
 Genetic factor
 Seasonal factor
 Overstrain
 Emotional disturbance
 Malnutrition
 Vitamin D deficiency
 Jaundice
 Pregnancy
 Diet,
 Psychosomatic disorders,
 Trauma,
 Endocrine dysfunction,
 Hereditary influences,
 Infection
 3 Stages-
1. Synovitis
2. Destruction
3. Deformity
Vascular congestion
Infiltration of synovial layer
Persistent inflammation
Destruction of joints and tendons
Erosion of articular cartilage
Osteoporotic changes
Joint subluxation and deformity
a
 Stage I. Inflammation of the synovial membrane spreads
to articular cartilage and other soft tissues. There occurs
limitation of joint movements with pain and muscle
spasm.
 Stage II. Granulation tissue formation occurs within the
synovial membrane and spreads to the periarticular
tissues. The cartilage starts disintegrating and the joint is
filled with granulation tissue. There occurs thickening of
the joint capsule, tendons and their sheaths impairing the
joint movement permanently
 Stage III. The granulation tissue  fibrous
tissue  adhesion formation between the
tendons, joint capsule and the articular
surfaces. The articular surfaces get partly
covered by cartilage and partly by fibrous
tissue gives rise to contractures and even
ankylosis of the joint, or secondary
osteoarthritis.
According to the American College of Rheumatology in 1987
revised criteria, at least 4 out of 7 criteria should be fulfilled
to make a diagnosis of rheumatoid arthritis.
 • Morning stiffness for minimum one hour everyday, at
least for six weeks.
 • Arthritis or swelling of three or more joints for > 6
weeks.
 • Arthritis or swelling of hand joints (wrist, metacarpal)
for more than 6 weeks.
 • Symmetrical swelling (arthritis of same joint areas) more
than 6 weeks.
 • Serum rheumatoid factor present.
 • Radiographic features of RA.
 • Rheumatoid nodules.
 Acute stage –
 Joint pain
 Swelling
 Early morning stiffness
 Loss of movements if small joints affected
 Tenderness
 Warmth and stiffness if large joints affected
 Chronic stage
 Joint deformities
 Dislocation of small joints (if affected)
 Restricted ROM
 Pain and stiffness in cervical spine(if affected)
 ADL affected
 Sub cutaneous nodules
 Muscle wasting
 Lungs – pleural effusion, bronchitis
 Heart – pericarditis, endocarditis and
myocardial diseases
 Neuropathies – mononeuritis multiplex
 Mouth – dryness of mouth
 Kidney and spleen can also be affected
 Subjective –
 Chief complaints:
• Pain in bilateral joints
• Morning stiffness
• Unable to do movements freely
• Difficulty in daily activities
• May complain of neck pain
 Pain assessment:
• Onset – Gradual
• Site – body chart, UL more common than LL,
peripheral joints> vertebral joints
• Severity – VAS
• Nature – constant, dull aching or sharp
• Aggravating Factors – movements, cold
climate, pressure of clothes
• Relieving Factors – sometimes at rest
 Level of pain
1. Pain after specific activities
2. Pain during and after activities but it doesn't
affect performance
3. Pain affects performance
4. Pain present in ADL
5. Constant dull aching pain without
disturbing sleep
6. Pain disturbing sleep
 On Observation
 Deformities –
• Hand – boutonniere deformity( Flexed PIP,
Extended DIP), Swan neck deformity(PIP
hyperextended, DIP flexion)
• Wrist – flexion deformity
• Elbow – flexion deformity
• Knees – flexion, valgus, wind swept
deformity, Baker’s cyst – popliteal fossa
• Feets – lateral deviation of toes, MT heads
prominent on plantar aspect, hallux valgus,
bunion, pes cavus, claw toes
 External appliances – assistive devices, splints
can be present
 Skin – papery, shiny and thin
 On Palpation –
 Warmth – may or may not be present
 Tenderness – can be present
 Effusion – can be present in large joints
 Swelling – will be present
 On examination –
 Deformities – will be present, check whether
it is fixed or correctable by passive methods
 ROM – will be restricted
 Limb length – may or may not be affected
 Gait analysis – will be affected – limping gait/
antalgic gait can be present
 Investigations
 Blood culture
• ESR – increased
• Serum albumin – decreased
• Globulin – increased
• Platelets – increased
• WBC – increased
• Rheumatoid factor - positive
 Synovial fluid examination –
• Yellow, watery, turbid
• Low sugar
• WBC- increased
 Radiographs
• To rule out deformities
• Atlanto axial subluxation can be seen in
cervical spine
 Tendon rupture
 Cord compression
 Osteoporosis
 C1-c2 subluxation - quadriparesis
 Classification of Functional Capacity for RA
1. Complete functional capacity with ability to
carry on all normal duties
2. Functional capacity adequate to conduct
normal activities despite of discomfort or
limited mobility of one or more joints
3. Functional capacity adequate to perform
only a few or none of the duties of usual
occupation or self care
4. Largely or wholly in capitated. Patient will be
bed ridden or confined to wheel chair,
permitting little or no self care
 Criteria for diagnosis of RA- any 4 or more
symptoms should be present
1. Early morning stiffness
2. Involvement of more than 3 joints
3. Symmetrical involvement
4. Subcutaneous nodules
5. RH factor positive
6. X ray of hand and wrist involved for 6 weeks
or more
 Home programme
 Follow up
 Rest
 Continuous Splinting
 NSAIDS
 Immunosuppressive Drugs
 Local Injection
 Aims-
 To relieve pain and muscle spasm
 To decrease the acute inflammation
 To improve muscle strength
 To train patient for independent ambulation
 To increase endurance
 To prevent and correct deformity
 To maintain and improve muscle tone
 To improve respiratory and circulatory conditions
 To improve ADL
 Means-
1. Acute inflammation
 Rest
 Joint protection – splinting, assistive device,
ambulatory aids
 Relaxation
2. Pain
 Physical modalities – moist pack/cryotherapy,
TENS/IFT
3. ROM
 PROM exercises, AROM exs, Stretching
4. For muscle weakness
 Strengthening – isometric, isotonic, isokinetic
5. Ambulation
 Ambulatory aids
 Orthosis
 Gait training
6. To increase endurance
 Energy conservation techniques
 Aerobic exercise program
7. Difficulty in ADL
 Adaptive equipments
 Assistive devices
8. Deformity correction
 Passive stretching
 Splinting
 Serial stretching (POP)
 Traction
 Acute or active phase of the disease the acute
symptoms - pain, erythema, tenderness and
swelling - are present.
 1. Positioning - of the involved joints and
correct bed posture.
 Firm mattress or occasional back support
minimizes the effects of malpositioning and
preserves the integrity of the affected joints.
 The limb is positioned in level of minimal
discomfort.
 Contracture Prone positions should be
avoided.
 2. Splints and sand bags  provide
additional support to the limb.
 Special attention is needed for the knee and
elbow joints  prone to develop flexion
contractures.
 The use of casts  minimum. The splints or
the casts should be checked regularly to
avoid complications.
 3. Deep breathing exercises  to improve the
vital capacity.
 4. The joints and muscles free from
immobilization and the active disease  full
ROM and progressive resistive exercise (PRE).
 5. The functional mobility should be
encouraged and maintained.
 6. Postural guidance and the methods of
performing activities without putting extra-
strain on the affected joints are taught.
 7. In cases with involvement of the weight
bearing joints the upper extremities should
be prepared for future crutch walking.
 8.Isometrics: Isometric exercises do not
involve the movements of the joints and are
therefore relatively painless.
 Should be started early.
 The muscles like quadriceps and deltoid are
susceptible to disuse atrophy and hence need
repeated sessions of isometrics.
 The other functional muscles concerned with
weight bearing and body balance need
strengthening and improved endurance.
 9. Speedy isometrics to the affected limb in
elevation reduce swelling and effusion
(especially of the knee).
 10.No heat therapy should be given to the
joints which are already warm.
 11.TENS, pulsed ultrasound for longer
periods offer reduction in the muscle spasm
and pain.
 13.Properly guided pool therapy for the
whole body provides an ideal medium for
exercises.
 14. Splinting
 WHO
 Splinting should be given in functional
position of hand – 5-10 degrees of wrist
flexion, 10-20 degrees of MCP flexion and
10-15 degrees of PIP flexion
 For swan neck deformity – double ring flexion
splint
 For boutonniere deformity – double ring
extension splint
 Wax therapy – – relieves morning stiffness
 HWF – 5-10 mins
 Correction of deformity
 Patient education by joint protection and
energy conservation techniques
 Four Ps
1. Pacing
2. Priority
3. Planning
4. Positioning
 It is a phase of vigorous activity to train the
patient to use the involved joints to the greatest
extent for physical independence.
 By 4-5 weeks of the onset independent sitting by
the use of hands can be started.
 If pain permits, active and functional therapeutic
programs should be initiated include standing
and walking.
 weight bearing should be deferred till pain and
discomfort subside
 Before allowing weight bearing it is absolutely
essential to provide the necessary orthotic support or
walking aid to relieve compressive forces on the
affected joints.
 This should be done between the parallel bars to
judge the effects of weight bearing on the diseased
joints.
 Sustained or intermittent stretching  for muscles
which have developed tightness or contractures
during the acute phase.
 Deep heat , ultrasound, TENS and other adjuncts may
be used to relieve pain.
 Efforts should be made to improve the
strength and endurance of the muscles
related to the affected joints.
 Job-oriented performance to be imparted in
the exercise regime.
 Relapse
 Relapse is common RA. It should be treated
on the same lines as detailed for the acute
phase.
 Usual sites of contractures and their
prevention
 Since it is a systemic disease, it is usually
accompanied by early fatigue. Therefore,
exercise sessions should be brief.
 The prognosis of the disease is very much
unpredictable. There may be:
 (a) Partial or total remission;
 (b) Remaining as a mild disease;
 (c) Insidious progressive in nature;
 (d) Progressive, but the progress of the
disease may be (i) rapid (ii) slow or (iii)
intermediate.
 Synovectomy
 Soft tissue release
 Osteotomy
 Arthroplasty
 Arthrodesis
 Tendon repair or transfer

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RHEUMATOID ARTHRITIS (RA).pptx

  • 2.  RA is a non suppurative, systemic, inflammatory disease of unknown cause characterized by polyarthritis of symmetrical joints and involving the peripheral joints and extra articular surface
  • 3.  Gender :F>M; 3:1  Age: 35-55 – years
  • 4.  Idiopathic  Abnormal immunological reaction  Antigenic agents, which probably act as predisposing factors, are viruses: rubella, Epstein-Barr, etc. genetic (common in people with HLA DR4 60%), psychological stress, allergic factors, endocrine factors and metabolic factors.
  • 5.  Genetic factor  Seasonal factor  Overstrain  Emotional disturbance  Malnutrition  Vitamin D deficiency  Jaundice  Pregnancy
  • 6.  Diet,  Psychosomatic disorders,  Trauma,  Endocrine dysfunction,  Hereditary influences,  Infection
  • 7.  3 Stages- 1. Synovitis 2. Destruction 3. Deformity
  • 8. Vascular congestion Infiltration of synovial layer Persistent inflammation Destruction of joints and tendons
  • 9. Erosion of articular cartilage Osteoporotic changes Joint subluxation and deformity a
  • 10.  Stage I. Inflammation of the synovial membrane spreads to articular cartilage and other soft tissues. There occurs limitation of joint movements with pain and muscle spasm.  Stage II. Granulation tissue formation occurs within the synovial membrane and spreads to the periarticular tissues. The cartilage starts disintegrating and the joint is filled with granulation tissue. There occurs thickening of the joint capsule, tendons and their sheaths impairing the joint movement permanently
  • 11.  Stage III. The granulation tissue  fibrous tissue  adhesion formation between the tendons, joint capsule and the articular surfaces. The articular surfaces get partly covered by cartilage and partly by fibrous tissue gives rise to contractures and even ankylosis of the joint, or secondary osteoarthritis.
  • 12. According to the American College of Rheumatology in 1987 revised criteria, at least 4 out of 7 criteria should be fulfilled to make a diagnosis of rheumatoid arthritis.  • Morning stiffness for minimum one hour everyday, at least for six weeks.  • Arthritis or swelling of three or more joints for > 6 weeks.  • Arthritis or swelling of hand joints (wrist, metacarpal) for more than 6 weeks.  • Symmetrical swelling (arthritis of same joint areas) more than 6 weeks.  • Serum rheumatoid factor present.  • Radiographic features of RA.  • Rheumatoid nodules.
  • 13.  Acute stage –  Joint pain  Swelling  Early morning stiffness  Loss of movements if small joints affected  Tenderness  Warmth and stiffness if large joints affected
  • 14.  Chronic stage  Joint deformities  Dislocation of small joints (if affected)  Restricted ROM  Pain and stiffness in cervical spine(if affected)  ADL affected
  • 15.
  • 16.  Sub cutaneous nodules  Muscle wasting  Lungs – pleural effusion, bronchitis  Heart – pericarditis, endocarditis and myocardial diseases  Neuropathies – mononeuritis multiplex  Mouth – dryness of mouth  Kidney and spleen can also be affected
  • 17.  Subjective –  Chief complaints: • Pain in bilateral joints • Morning stiffness • Unable to do movements freely • Difficulty in daily activities • May complain of neck pain
  • 18.  Pain assessment: • Onset – Gradual • Site – body chart, UL more common than LL, peripheral joints> vertebral joints • Severity – VAS • Nature – constant, dull aching or sharp • Aggravating Factors – movements, cold climate, pressure of clothes • Relieving Factors – sometimes at rest
  • 19.
  • 20.  Level of pain 1. Pain after specific activities 2. Pain during and after activities but it doesn't affect performance 3. Pain affects performance 4. Pain present in ADL 5. Constant dull aching pain without disturbing sleep 6. Pain disturbing sleep
  • 21.  On Observation  Deformities – • Hand – boutonniere deformity( Flexed PIP, Extended DIP), Swan neck deformity(PIP hyperextended, DIP flexion) • Wrist – flexion deformity • Elbow – flexion deformity • Knees – flexion, valgus, wind swept deformity, Baker’s cyst – popliteal fossa
  • 22.
  • 23.
  • 24.
  • 25. • Feets – lateral deviation of toes, MT heads prominent on plantar aspect, hallux valgus, bunion, pes cavus, claw toes  External appliances – assistive devices, splints can be present  Skin – papery, shiny and thin
  • 26.
  • 27.  On Palpation –  Warmth – may or may not be present  Tenderness – can be present  Effusion – can be present in large joints  Swelling – will be present
  • 28.  On examination –  Deformities – will be present, check whether it is fixed or correctable by passive methods  ROM – will be restricted  Limb length – may or may not be affected  Gait analysis – will be affected – limping gait/ antalgic gait can be present
  • 29.  Investigations  Blood culture • ESR – increased • Serum albumin – decreased • Globulin – increased • Platelets – increased • WBC – increased • Rheumatoid factor - positive
  • 30.  Synovial fluid examination – • Yellow, watery, turbid • Low sugar • WBC- increased
  • 31.  Radiographs • To rule out deformities • Atlanto axial subluxation can be seen in cervical spine
  • 32.
  • 33.
  • 34.
  • 35.  Tendon rupture  Cord compression  Osteoporosis  C1-c2 subluxation - quadriparesis
  • 36.  Classification of Functional Capacity for RA 1. Complete functional capacity with ability to carry on all normal duties 2. Functional capacity adequate to conduct normal activities despite of discomfort or limited mobility of one or more joints 3. Functional capacity adequate to perform only a few or none of the duties of usual occupation or self care
  • 37. 4. Largely or wholly in capitated. Patient will be bed ridden or confined to wheel chair, permitting little or no self care
  • 38.  Criteria for diagnosis of RA- any 4 or more symptoms should be present 1. Early morning stiffness 2. Involvement of more than 3 joints 3. Symmetrical involvement 4. Subcutaneous nodules 5. RH factor positive 6. X ray of hand and wrist involved for 6 weeks or more
  • 40.
  • 41.  Rest  Continuous Splinting  NSAIDS  Immunosuppressive Drugs  Local Injection
  • 42.  Aims-  To relieve pain and muscle spasm  To decrease the acute inflammation  To improve muscle strength  To train patient for independent ambulation  To increase endurance  To prevent and correct deformity  To maintain and improve muscle tone  To improve respiratory and circulatory conditions  To improve ADL
  • 43.  Means- 1. Acute inflammation  Rest  Joint protection – splinting, assistive device, ambulatory aids  Relaxation
  • 44. 2. Pain  Physical modalities – moist pack/cryotherapy, TENS/IFT 3. ROM  PROM exercises, AROM exs, Stretching 4. For muscle weakness  Strengthening – isometric, isotonic, isokinetic
  • 45. 5. Ambulation  Ambulatory aids  Orthosis  Gait training 6. To increase endurance  Energy conservation techniques  Aerobic exercise program 7. Difficulty in ADL  Adaptive equipments  Assistive devices
  • 46. 8. Deformity correction  Passive stretching  Splinting  Serial stretching (POP)  Traction
  • 47.
  • 48.  Acute or active phase of the disease the acute symptoms - pain, erythema, tenderness and swelling - are present.  1. Positioning - of the involved joints and correct bed posture.  Firm mattress or occasional back support minimizes the effects of malpositioning and preserves the integrity of the affected joints.  The limb is positioned in level of minimal discomfort.  Contracture Prone positions should be avoided.
  • 49.  2. Splints and sand bags  provide additional support to the limb.  Special attention is needed for the knee and elbow joints  prone to develop flexion contractures.  The use of casts  minimum. The splints or the casts should be checked regularly to avoid complications.
  • 50.  3. Deep breathing exercises  to improve the vital capacity.  4. The joints and muscles free from immobilization and the active disease  full ROM and progressive resistive exercise (PRE).  5. The functional mobility should be encouraged and maintained.
  • 51.  6. Postural guidance and the methods of performing activities without putting extra- strain on the affected joints are taught.  7. In cases with involvement of the weight bearing joints the upper extremities should be prepared for future crutch walking.
  • 52.  8.Isometrics: Isometric exercises do not involve the movements of the joints and are therefore relatively painless.  Should be started early.  The muscles like quadriceps and deltoid are susceptible to disuse atrophy and hence need repeated sessions of isometrics.  The other functional muscles concerned with weight bearing and body balance need strengthening and improved endurance.
  • 53.  9. Speedy isometrics to the affected limb in elevation reduce swelling and effusion (especially of the knee).  10.No heat therapy should be given to the joints which are already warm.  11.TENS, pulsed ultrasound for longer periods offer reduction in the muscle spasm and pain.
  • 54.  13.Properly guided pool therapy for the whole body provides an ideal medium for exercises.
  • 55.  14. Splinting  WHO  Splinting should be given in functional position of hand – 5-10 degrees of wrist flexion, 10-20 degrees of MCP flexion and 10-15 degrees of PIP flexion  For swan neck deformity – double ring flexion splint  For boutonniere deformity – double ring extension splint
  • 56.  Wax therapy – – relieves morning stiffness  HWF – 5-10 mins  Correction of deformity  Patient education by joint protection and energy conservation techniques  Four Ps 1. Pacing 2. Priority 3. Planning 4. Positioning
  • 57.  It is a phase of vigorous activity to train the patient to use the involved joints to the greatest extent for physical independence.  By 4-5 weeks of the onset independent sitting by the use of hands can be started.  If pain permits, active and functional therapeutic programs should be initiated include standing and walking.  weight bearing should be deferred till pain and discomfort subside
  • 58.  Before allowing weight bearing it is absolutely essential to provide the necessary orthotic support or walking aid to relieve compressive forces on the affected joints.  This should be done between the parallel bars to judge the effects of weight bearing on the diseased joints.  Sustained or intermittent stretching  for muscles which have developed tightness or contractures during the acute phase.  Deep heat , ultrasound, TENS and other adjuncts may be used to relieve pain.
  • 59.  Efforts should be made to improve the strength and endurance of the muscles related to the affected joints.  Job-oriented performance to be imparted in the exercise regime.  Relapse  Relapse is common RA. It should be treated on the same lines as detailed for the acute phase.  Usual sites of contractures and their prevention  Since it is a systemic disease, it is usually accompanied by early fatigue. Therefore, exercise sessions should be brief.
  • 60.
  • 61.
  • 62.
  • 63.
  • 64.
  • 65.  The prognosis of the disease is very much unpredictable. There may be:  (a) Partial or total remission;  (b) Remaining as a mild disease;  (c) Insidious progressive in nature;  (d) Progressive, but the progress of the disease may be (i) rapid (ii) slow or (iii) intermediate.
  • 66.  Synovectomy  Soft tissue release  Osteotomy  Arthroplasty  Arthrodesis  Tendon repair or transfer

Editor's Notes

  1. Wind swept – one knee in severe valgus and another in severe valgus