For B.Pharm, 6th Semester

1. Nutriceutical
NEUTRACEUTICALs

2. DEFINITION
• The term “Nutraceutical” was coined from
“Nutrition” & “Pharmaceutical” in 1989 by
Stephen DeFelice MD, Founder and Chairman of
the Foundation for Innovation in Medicine (FIM).
• Other words used in the context: Dietary
supplements, Functional food, Multi-functional
Food, etc.
• NEUTRACEUTICAL is any substance that is a
food or a part of food and provides medical or
health benefits, including the prevention and
treatment of disease.

4. BENEFITS OF NEUTRACEUTICALS
May increase the health value of our diet.
May help us live longer.
May help us to avoid particular medical
conditions.
May have a psychological benefit from doing
something for oneself.
May be perceived to be more "natural" than
traditional medicine and less likely to produce
unpleasant side-effects.
May present food for populations with special
needs (e.g. nutrient-dense foods for the elderly).

5. • According to American association of nutritional chemists-
• The product that has been isolated or purified from food and
generally sold in medicinal forms not usually associated with
food.
• With passage of dietary supplement, health and education
act (dshea)-
• Is a product (other than tobacco) that is intended to supplement
the diet that bears or contains one or more of the following
dietary ingredients: a vitamin, a mineral, an herb or other
botanical, an amino acid, a dietary substance for use by man to
supplement the diet by increasing the total daily intake, or a
concentrate, metabolite, constituent, extract, or combinations
of these ingredients.
• Is intended for ingestion in pill, capsule, tablet, or liquid form.
• Is not represented for use as a conventional food or as the sole
item of a meal or diet.

6. CLASSIFICATION
• Neutraceuticals can be classified based on:
1.Natural source (Food Source)
2.Pharmacological conditions
3.Chemical constitution

7. 1. Based on FOOD SOURCE
• Plants– Lycopene, curcumin, ascorbic acid,
quercetin,catechins,pectin,elagic acid.
• Animals– Conjugated lenoleic acid(CLA),
DHA (docosahexaenoic acid),
EPA(Ecosapentanoic acid), choline.
• Microorganism- Bifidobacterium,
Lactobacilli, yeast, streptococcus.

8. 2. Base on Pharmacological condition

9. 3. Based on Chemical constituents

10. CATEGORIS OF NEUTRACEUTICALS

11. Broadly can be defined as
• Nutrients: Substances which have established
nutritional functions e.g. Vitamins, Minerals,
Amino Acids, Fatty acids, etc.
• Herbals/Phytochemicals : Herbs or Botanical
products.
• Dietary Supplements : Probiotics, Prebiotics,
Antioxidants, Enzymes, etc.

12. INORGANICMINERAL SUPPLEMENT
• Calcium: for bone loss & prevention
• Magnesium: involved in 300 enzymatic rxn & in
maintanance of calcium.
• Manganese: Enzymatic rxn & bone & cartilage
formation
• Boron: for calcium & estrogen level in women
• Copper: for all tissue (absorb when bound with Aa)
• Zinc: Antioxidant system by scavenging free radicals
• Phosphorus: Maintain bone structure & plasma
formation
• Silicon: Bone formation & calcification.
• Vitamin: B1, B2, B6, B12, C, D, A, E, K.

14. Source: Chauhan, et al. 2013

15. Indian Market

16. Source: https://www.theinsightpartners.com/reports/nutraceuticals-market
Products and Percentages

17. SCOPES OF NUTRACEUTICALS

19. SOME HEALTHIEST FRUITS AND
VEGETABLES

21. Herbs/Natural products as health food:
• FENUGREEK
• SOURCE : Trigonella foenum-
graecum
• FAMILY: Leguminoseae
• CHEMICAL CONSTITUENTS :
• Alkaloids (gentianine and
trigonelline).
• flavanoids, coumarins,
proteins,amino acids, steroid
saponins.

22. FENUGREEK
• USES :
• In treatment of anorexia, gastritis.
• Fenugreek possess laxative, expectorant,
demulcent properties.
• Shows hypoglycemic and
hypocholesterolemic properties

23. GINSENG
• SOURCE : Panax ginseng
• FAMILY: Araliaceae
• CHEMICAL
CONSTITUENTS:
• Protopanaxadiol
Polysaccharides, Starch,
sterols, Polyacetylenes,
choline, Vitamins
B1,B2,B12, Pantothenic
acid, biotin (B6).

24. GINSENG
• USES :
• Ginseng helps the body to cope
with stress and fatigue
• In treatment of hypertension
and hypoglycemia.
• Modifies liver function and
metabolism.

25. EXAMPLES OF NUTRACEUTICALS
CURRENTLY AVAILABLE IN MARKET
• VITAMIN AND MINERAL
SUPPLEMENTS :
• Vitamin-A (Beta- Carotene)
• ADDITIONAL SUPPLEMENTS :
• Cod liver oil, primrose oil,
glucosamine, garlic etc.
• SPORTS PRODUCTS Glucon-
• D (Heinz), Glucose D (Dabur)

26. MARKETED PREPARATIONS

27. REFERENCES
• De Felice L Stephen. The nutraceutical revolution, its
impact on food industry. Trends in Food Sci. and Tech
1995; 6:59-61.
• Jack DB. Keep taking the tomatoes - the exciting world
of nutraceuticals. Mol Med Today 1995; 1(3):118-21.
• Brower B. Nutraceuticals: poised for a healthy slice of
the market. Nat Biotechnology 1998; 16: 728-33.
• Mannion M. Nutraceutical revolution continues at
foundation for innovation in medicine conference.Am J
NatMed 1998; 5:30-3.
• Pharmacognosy & Phytochemistry, Volume II, Vinod D.
Rangari, pg. no. 100- 124. career piblication.
• Text book of pharmacognosy and phytochemistry by
Biren shah and A.K.Seth, pg.no-471-479.