How strong is Alabama's biotechnology industry? Read this report to learn about it.

1.
ALABAMA
Alabama has an employment specialization in the agricultural feedstock and chemicals subsector (location
quotient of 1.77). Academic research expenditures in biosciences totaled $512 million in 2008, heavily
weighted to medical sciences ($299 million) and accounting for a higher percentage of both per capita and
total academic research expenditures than the national average. Over the last six years, the largest share of
the State’s $135 million in venture capital investments was made in the medical diagnostics segment. With
2,949 postsecondary degrees in bioscience fields, Alabama placed higher than its population rank. The degrees
were concentrated in biological sciences and other life science fields.
 Bioscience Performance Metrics
Summary of State Performance in Selected Bioscience‐related Metrics
Metrics Alabama United States Rank*
Bioscience Industry, 2008
Total Bioscience Industry Employment, 2008 10,146 1,420,324 III
Bioscience Industry Location Quotient, 2008 0.52 n/a IV
Biosciences Industry Establishments, 2008 557 47,593 III
Academic R&D Expenditures, FY 2008
Bioscience R&D ($ thousands) $512,384 $31,818,810 19
Bioscience Share of Total R&D 72.4% 61.3% 8
Bioscience R&D Per Capita $109.54 $104.54 17
Change in Bioscience R&D, FY 2004–08 24.1% 22.3% 16
NIH Funding, FY 2009
Total, Including ARRA Funds ($ thousands) $290,726 $25,837,590 23
Per Capita Funding $61.74 $84.16 26
Change in Baseline Funding, FY 2004–09** ‐26.1% ‐4.7% 49
Change in Total Funding, FY 2004–09 ‐9.7% 14.6% 49
Clinical Trials, Initiated 2009 356 5,299 23
Higher Education Degrees in Bioscience Fields, AY 2008 2,949 161,811 19
Employment in Bioscience‐related Occupations, 2008 7,280 717,510 28
Bioscience Venture Capital Investments, 2004–09 ($ millions) $134.7 $60,099 30
Bioscience and Related Patents, 2004–09 493 75,593 29
*State ranking figures for bioscience industry employment metrics are calculated as quintiles (I=Top Quintile; V=Bottom Quintile). All other metrics are ranked 1‐52.
Alabama Page 1
**Baseline Funding does not include American Recovery and Reinvestment Act (ARRA) funds for 2009.
For source notes, see end of State Profile.
Battelle/BIO State Bioscience Initiatives 2010

2.
 Bioscience Industry Base, 2008
INDUSTRY SUBSECTOR Alabama United States
2008 2001–08 Change 2008 2001–08 Change
AGRICULTURAL FEEDSTOCK & CHEMICALS
Establishments 41 0.7% 2,440 16.0%
Employment 2,800 ‐30.6% 114,793 1.9%
Location Quotient 1.77 n/a
Direct‐Effect Employment Multiplier 6.68 11.33
Total Employment Impact 18,709 1,284,650
Average Annual Wage $74,469 $72,279
DRUGS & PHARMACEUTICALS
Establishments 14 7.7% 2,771 6.4%
Employment 783 172.8% 311,882 2.3%
Location Quotient 0.18 n/a
Direct‐Effect Employment Multiplier 3.63 9.92
Total Employment Impact 2,844 2,873,278
Average Annual Wage $51,043 $93,378
MEDICAL DEVICES & EQUIPMENT
Establishments 173 ‐14.2% 15,227 0.4%
Employment 2,779 ‐8.5% 435,509 2.0%
Location Quotient 0.46 n/a
Direct‐Effect Employment Multiplier 2.47 4.87
Total Employment Impact 6,874 2,029,581
Average Annual Wage $38,363 $63,606
RESEARCH, TESTING, & MEDICAL LABORATORIES
Establishments 329 55.9% 27,154 57.7%
Employment 3,783 5.4% 558,140 46.1%
Location Quotient 0.49 n/a
Direct‐Effect Employment Multiplier 2.43 3.30
Total Employment Impact 9,207 1,853,127
Average Annual Wage $56,085 $80,785
TOTAL BIOSCIENCES INDUSTRY
Establishments 557 19.4% 47,593 28.3%
Employment 10,146 ‐7.3% 1,420,324 15.8%
Location Quotient 0.52 n/a
Direct‐Effect Employment Multiplier 3.71 5.82
Total Employment Impact 37,634 8,040,636
Average Annual Wage $55,916 $77,595
TOTAL PRIVATE SECTOR
Establishments 114,777 7.8% 8,860,956 13.8%
Employment 1,570,232 3.3% 113,917,377 3.5%
Average Annual Wage $37,772 $45,229
Note: U.S. employment metrics include Puerto Rico. Estimates of total employment impacts do not include Puerto Rico.
Alabama Page 2
Battelle/BIO State Bioscience Initiatives 2010

3.
 Bioscience Performance Metrics
Bioscience Academic R&D Expenditures NIH Awards in Alabama, 2004–2009
in Alabama, FY 2008
Medical 2004
$298,990 $322
Sciences
2005
Biological $297
$125,776
Sciences
2006
$284
Agricultural
$72,599
Sciences
2007
$273
Other
$13,902
Life Sciences 2008
$253
Bio/Biomedical
$1,117 2009
Engineering ARRA $291
$0 $75,000 $150,000 $225,000 $300,000 $0 $50 $100 $150 $200 $250 $300 $350
Academic R&D Expenditures ($ Thousands)
NIH Funding ($ Millions)
 Recent Clinical Trial Activities
Clinical Trials by Phase in Alabama, 2009 Clinical Trials by Major Disease Category
in Alabama, 2009
100
92
Phase I 17
81
80 77
64
Phase II 105 60 57
40
33
Phase III 163 30
20
Phase IV 20
0
Cancer Circulatory Heart Infectious Neurologic Nutritional Other
Disease Disease &
0 30 60 90 120 150 180
Metabolic
Clinical Trials Disease Category
Alabama Page 3
Battelle/BIO State Bioscience Initiatives 2010

4.
 Bioscience Talent Base
Bioscience‐related Occupational Employment Bioscience‐related Degrees in Alabama, AY 2008
in Alabama, 2008
Agricultural, Food & Agricultural, Food,
Nutrition Scientists & 220 & Nutrition Science
Technicians
Biological Sciences
Biological Scientists
1,000
& Technicians
Bio‐Medical Sciences Associate's (AA/AAS)
& Engineering
Medical & Clinical Bachelor's (BS/BA)
Laboratory 5,960
Technicians Medical & Veterinary Master's (MS/MA)
Sciences
Doctorate (PhD)
Biomedical &
Biochemical 100 Other Life Science
Scientists & Engineers Fields
0 1,000 2,000 3,000 4,000 5,000 6,000 0 500 1,000 1,500
Occupational Employment Degrees
 Bioscience Venture Capital
Bioscience‐related Venture Capital Investments Bioscience‐related Venture Capital Investments
in Alabama, 2004–2009 in Alabama by Segment, 2004–2009
Biofuels $12.5
2004 $18.8
Biosensors
2005 $48.6
Biotech‐Animal
Biotech‐Equipment
2006
Biotech‐Human $32.5
2007 $18.9
Biotech‐Industrial
Biotech‐Other
2008 $5.3
Biotech‐Research $0.9
2009 $43.2
Med/Health‐Info Tech $34.8
$0 $10 $20 $30 $40 $50 Med/Health‐Products $1.5
Venture Capital Investments ($ Millions) Med/Health‐Services $0.1
Medical Diagnostics $37.6
Medical Therapeutics $2.9
$0 $10 $20 $30 $40
Alabama Page 4
Venture Capital Investments ($ Millions)
Battelle/BIO State Bioscience Initiatives 2010

5.
 Bioscience Patents
Bioscience‐related Patents in Alabama, 2004–2009 Bioscience‐related Patents by Classification Group
in Alabama, 2004–2009
Agricultural
2004 93 Bioscience 35
Biochemistry 111
2005 74
Biotechnology 3
2006 86
Drugs &
Pharmaceuticals 167
2007 93
Surgical & Medical
Instruments 95
2008 66 Other Medical
Equipment 27
2009 81 Other Bioscience‐
Related 55
0 20 40 60 80 100 0 50 100 150 200
Patents Patents
State Bioscience Contacts
Biotechnology Association of Alabama
500 Beacon Parkway West
Birmingham, AL 35209
P: (205) 943‐5124
F: (205) 943‐4748
www.bioalabama.com
Source Notes:
Employment, Establishment, and Wage Data: U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (QCEW)
industry data provided by the Minnesota IMPLAN Group, 2001 and 2008.
Employment Multipliers: U.S. Bureau of Economic Analysis RIMS II Employment Multipliers, 2006 (most currently available).
Academic R&D Expenditures: National Science Foundation (NSF) Survey of Research and Development Expenditures at Universities
and Colleges, 2004 and 2008.
NIH Funding: National Institutes of Health, Office of Extramural Research, Award Trends, Dollars Awarded by State, 2004 and 2009.
Clinical Trials: National Institutes of Health, Clinicaltrials.gov, trials that were initiated in 2009.
Alabama Page 5
Higher Education Degrees: National Center for Educational Statistics, Integrated Postsecondary Education Data System (IPEDS), 2008.
Occupational Employment: U.S. Bureau of Labor Statistics, Occupational Employment Statistics (OES) survey data, 2008.
Venture Capital: Thomson Reuters’ VentureXpert Database, 2004–2009, as of January 15, 2010.
Patents: U.S. Patent & Trademark Office data as available from the Thomson Reuters’ Delphion Patent Analysis Database,
2004–2009, as of January 15, 2010.
For a more detailed discussion of the data and methodology used, please see the Appendix to the full national report. ©2010
Battelle/BIO State Bioscience Initiatives 2010