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Medillectuals Juniors
Researched by + QMs: Sneha,
Srividya, Lajja, Dev
(and also Satwik and Utkarsh  )
Prelims
30 Questions
1 mark per question
Some have Part points
1 minute per question
Commencing in 3….2…..1…..
1. Alkaline phosphatase:
gamma glutamyl
transferase is the same as
amylase : what?
2. During which
stage(systole/diastole) of
cardiac cycle is the blood
flow to the right ventricle
the highest?
3. Following is the ecg record of a
patient with deviation in the mean
axis. Predict whether it is left/right
axis deviation and give the
range(quadrant). Eg.0 to 90 degrees
4. With which
metabolic
pathways, do
these
polyketides
share their
biosynthesis?
5. A Journal of General Internal Medicine
study, published in 2010, investigated medical
errors from 1979 to 2006 in United States
hospitals and found that medication errors
increased 10% during the month of July , but
not in neighbouring private hospitals. Surgical
errors did not increase, leading to the
hypothesis that medication errors are easier
for new personnel to make because surgical
procedures are done through team work.
This study, though debunked by other studies
gave rise to a popular myth, X. In UK, this has
also been called Black Wednesday, or Killing
season, after usage in a British medical drama
series, Cardiac arrest. What is X?
with the center as
the ear canal and its
base extending
outwards along
which our ear is
incapable of
determining the
spatial source of the
sound using only
inter-aural time and
intensity differences.
How then are we
still able to localise
7. Damage to which muscle
and nerve is causing the
gait shown in the video?
(part points – 0.5 +0.5)
8. Why would a patient of
Chronic Granulomatous
Disease be more likely to
suffer from infections due to
Staphylococcus aureus?
9. Identify the tumor shown above. Prior
to surgically removing this tumor, which
class of drugs are to be used first? (Part
points – 1 +1)
10.The following are a part of an
exhaustive list. What is this list?
1. Essential fatty acid
2. Riboflavin
3. Biotin
4. Alcoholic extract of rice
5. Bioflavinoids
11. What does the above
infographic represent?
12. ‘Whoonga’ is a drug cocktail
smoked by individuals in South
Africa. Among other drugs, this
is said to contain antiretroviral
medications which have been
either stolen from those
infected with HIV or sold by
them on the black market. The
predominant ARV in this drug
cocktail has been found to have
effects similar to LSD, sharing
receptors in the brain. This
results in it’s psychoactive
effects, including hallucinations,
vivid dreams and night terrors.
Name the drug and the class it
belongs to? (part points- 1+0.5)
13. In a child with egg, peanuts
and pollen allergy, which common
vaccine is contraindicated and
why?
14. A Zinc smelter is brought to the
casualty with vomiting and diarrhoea
with rice water stools. O/E breath
has garlicy odour. What is the most
likely ECG finding?
15. Natalizumab is a monoclonal
antibody used to treat multiple
sclerosis and Crohn's disease. It acts
as an antibody against molecules
that reduces the ability of immune
cells to cross the blood brain barrier
and the intestinal wall.
1. What molecule does it target?
2. Which condition would a patient
receiving this drug be more
susceptible to? (part points- 1+1)
16. John Moore was a surveyor on the Alaska Pipeline who developed
bleeding gums, bruising and an enlargement of the abdomen. He was
diagnosed of ______ cancer. When they removed his spleen, it weighed
22 pounds whereas a normal spleen is just around 1 pound. The
following laboratory values are found:
WBC- 3,000/mm3
Platelets – 78,000/mm3
Neutrophils- 1600/mm3
Basophils-4/mm3
Eosinophils-60/mm3
His doctor, David Golde, without taking any consent from Moore, had
filed a patent on Moore's cell line called Mo and its market value was
estimated to be $3 billion. Moore filed a lawsuit against the doctor
asking for his share. Identify the cancer.
17.Macular sparing i.e. loss of peripheral
vision with intact macular vision occurs
because the macular area in the cortex
has dual arterial supply. Name and
identify the arteries involved on an
angiogram.
A
B
C
D
18.
19.Pituitary infarcts are rare but in
women who have an episode of
shock due to PPH, the pituitary
become infarcted. Why are these
women especially vulnerable to
these infarcts?
Time in hours
20.What does this graph represent?
What do the red lines represent?
21. A woman has a regular menstrual
cycle of 37 days duration. What is the
duration of her follicular and luteal
phases? Menstruation is for 4 days.
Scientific American :'Surprisingly,
even plants which use chlorophyll to
absorb light energy can suffer from a
condition analogous to X. The plant
disease causes the leaves to blister,
wither and die on exposure to
sunlight. The process is so similar to
the human condition X that some
researchers hope to find a cure for
the disease human condition by
studying the properties of so called
"vampire plants" like maize. ' Which
23.Why is the upstroke of pacemaker
potential due to calcium channels
and not fast sodium channels unlike
myocyte potential or nerve
potential?
24.Explain the reason behind the
plateau in the venous function curve.
25.nAChRs: Varenicline Bupropion
μ-opioid receptors: X and Y
Give X and Y. (Part points 1 + 1)
1. What does X represent?
2. Name a drug used for the
treatment of this condition
(Part points 1 + 1)
X
26.
27.
28. Ethacrynic Acid: Bartter
syndrome
Metolazone: X
Identify X
29. A young male
patient presented with
severe renal colic. The
observation made from
urinalysis is shown in
the image.
1. What is this finding?
2. What
gastrointestinal
pathology is he likely
to have?
(Part points will be
including the head. They are caught with
a particular kind of pots. These pots are
like octopus real estate, and are attached
to a long rope that is dropped into the
water, where they eventually settle on
the sea bottom. The unsuspecting
octopus, who lives on the sea floor,
comes along and says “Wow, a free
house!” and, feeling like he has just won
the lottery, sidles into his new abode,
and is cooked up by the happy hunter.
These pots have been made legendary in
Submit your sheets.
1. Alkaline phosphatase:
gamma glutamyl
transferase is the same as
amylase : what?
Lipase
2. During which
stage(systole/diastole) of
cardiac cycle is the blood
flow to the right ventricle
the highest?
Systole
3. Following is the ecg record of a
patient with deviation in the mean
axis. Predict whether it is left/right
axis deviation and give the
range(quadrant). Eg.0 to 90 degrees
90-180
4. With which
metabolic
pathways, do
these
polyketides
share their
biosynthesis?
Fatty Acid
Synthesis
5. A Journal of General Internal Medicine
study, published in 2010, investigated medical
errors from 1979 to 2006 in United States
hospitals and found that medication errors
increased 10% during the month of July , but
not in neighbouring private hospitals. Surgical
errors did not increase, leading to the
hypothesis that medication errors are easier
for new personnel to make because surgical
procedures are done through team work.
This study, though debunked by other studies
gave rise to a popular myth, X. In UK, this has
also been called Black Wednesday, or Killing
season, after usage in a British medical drama
series, Cardiac arrest. What is X?
July phenomenon – the time
when new residents join.
with the center as
the ear canal and its
base extending
outwards along
which our ear is
incapable of
determining the
spatial source of the
sound using only
inter-aural time and
intensity differences.
How then are we
still able to localise
Shape of the pinna
7. Damage to which muscle
and nerve is causing the
gait shown in the video?
(part points – 0.5 +0.5)
Gluteus maximus, inferior gluteal
nerve
8. Why would a patient of
Chronic Granulomatous
Disease be more likely to
suffer from infections due to
Staphylococcus aureus?
Catalase positive
9. Identify the tumor shown above.
Prior to surgically removing this tumor,
which class of drugs are to be used first?
(Part points – 1 +1)
Pheochromocytoma, Alpha
blockers
10.The following are a part of an
exhaustive list. What is this list?
1. Essential fatty acid
2. Riboflavin
3. Biotin
4. Alcoholic extract of rice
5. Bioflavinoids
The missing vitamins between
Vitamin E and K.
11. What does the above
infographic represent?
Transmission risk following
needle stick injury.
12. ‘Whoonga’ is a
drug cocktail smoked
by individuals in South
Africa. Among other
drugs, this is said to
contain antiretroviral
medications which
have been either stolen
from those infected
with HIV or sold by
them on the black
market. The
predominant ARV in
this drug cocktail has
been found to have
effects similar to LSD,
sharing receptors in
the brain. This results
in it’s psychoactive
effects, including
Efavirenz, NNRTI
13. In a child with egg, peanuts and pollen allergy,
which common vaccine is contraindicated and
why?
Influenza, yellow fever, because they
are cultured in egg.
14. A Zinc smelter is brought to the
casualty with vomiting and diarrhoea
with rice water stools. O/E breath has
garlicy odour. What is the most likely ECG
finding?
Arsenic poisoning, QTc
prolongation
15. Natalizumab is a monoclonal
antibody used to treat multiple
sclerosis and Crohn's disease. It acts
as an antibody against molecules
that reduces the ability of immune
cells to cross the blood brain barrier
and the intestinal wall.
1. What molecule does it target?
2. Which condition would a patient
receiving this drug be more
susceptible to? (part points- 1+1)
Integrin, JC virus
16. John Moore was a surveyor on the Alaska Pipeline who
developed bleeding gums, bruising and an enlargement of
the abdomen. He was diagnosed of ______ cancer. When
they removed his spleen, it weighed 22 pounds whereas a
normal spleen is just around 1 pound. The following
laboratory values are found:
WBC- 3,000/mm3
Platelets – 78,000/mm3
Neutrophils- 1600/mm3
Basophils-4/mm3
Eosinophils-60/mm3
His doctor, David Golde, without taking any consent from
Moore, had filed a patent on Moore's cell line called Mo
and its market value was estimated to be $3 billion. Moore
Hairy cell leukemia
17.Macular sparing i.e. loss of peripheral
vision with intact macular vision occurs
because the macular area in the cortex
has dual arterial supply. Name and
identify the arteries involved on an
angiogram.
A
B
C
D
A and green.
18.
Hereditary hemochromatosis
19.Pituitary infarcts are rare but in
women who have an episode of
shock due to PPH, the pituitary
become infarcted. Why are these
women especially vulnerable to
these infarcts?
The pituitary enlarges during
pregnancy.
Time in hours
20.What does this graph represent?
What do the red lines represent?
Sleep cycle, REM sleep.
21. A woman has a regular menstrual
cycle of 37 days duration. What is the
duration of her follicular and luteal
phases? Menstruation is for 4 days.
Follicular 23
luteal 14
Scientific American :'Surprisingly,
even plants which use chlorophyll to
absorb light energy can suffer from a
condition analogous to X. The plant
disease causes the leaves to blister,
wither and die on exposure to
sunlight. The process is so similar to
the human condition X that some
researchers hope to find a cure for
the disease human condition by
studying the properties of so called
"vampire plants" like maize. ' Which
Porphyria
23.Why is the upstroke of pacemaker
potential due to calcium channels
and not fast sodium channels unlike
myocyte potential or nerve
potential?
The resting membrane potential
of cardiac pacemaker cells is
less negative. Hence, the
sodium channels are in a
permanently inactivated state.
24.Explain the reason behind the
plateau in the venous function
curve.
Veins collapse at such low
pressures
25.nAChRs: Varenicline and Bupropion
μ-opioid receptors: X and Y
Give X and Y. (Part points will be given)
Partial agonist and antagonist.
Hence, Buprenorphine and
Naloxone/ naltrexone
1. What does X represent?
2. Name a drug used for the
treatment of this condition
(Part points will be given)
X
26
PNH
eculizumab
27.
Paget’s disease
28. Ethacrynic Acid: Bartter
syndrome
Metolazone: X
Identify X
Gitelman syndrome
29. A young male
patient presented with
severe renal colic. The
observation made from
urinalysis is shown in
the image.
1. What is this finding?
2. What
gastrointestinal
pathology is he likely
to have?
(Part points will be
Calcium oxalate crystals and
crohn’s disease.
including the head. They are caught with
a particular kind of pots. These pots are
like octopus real estate, and are attached
to a long rope that is dropped into the
water, where they eventually settle on
the sea bottom. The unsuspecting
octopus, who lives on the sea floor,
comes along and says “Wow, a free
house!” and, feeling like he has just won
the lottery, sidles into his new abode,
and is cooked up by the happy hunter.
These pots have been made legendary in
Takotsubo cardiomyopathy.
Medillectuals Junior Finals
Crossword
+5 for each, +10
Bonus for all
correct
Acros
s
2. 5th generation cephalosporin
walks into
your hospital,
which drug
toxicity would
he be
assumed to
have? P.S. he
has a history
of heart
break, so
treat him
9. Giant cells in measles ?
10. Erythromycin causes GI distress,
above that of usual drugs, due to its
action on?
11. Identify
the
procedure
shown.
12. In narcolepsy, there is decrease
in CSF concentration of?
Down.
1. Pringle’s manoeuvre is the
clamping of which abdominal
structure to prevent bleeding in the
abdominal cavity?
3. Total Parenteral Nutrition induced
cholelithiasis is due to decrease in
_______.
5. The following viruses have the
potential for reassortment:
Arenavirus
Orthomyxovirus
Reovirus
Complete the list.
6. Yawning is a withdrawal sign
of?
7. What is this
procedure
called?
8. Syndrome of apparent
mineralocorticoid excess, is due
to inhibition of 11 beta hydroxy
steroid dehydrogenase, due to
intake of?
Dry
• There are 9 questions in this round.
• Pounce +10, -5
• Infinite bounce +10, no negative
1. Expressing skepticism towards
which emerging field?
Immunotherapy for cancer
2.
Mermaid syndrome or sirenomelia-
an extreme case of caudal
regression syndrome
“And the LORD sent fiery serpents among the
people, and they bit the people; and much people
of Israel died. Therefore the people came to
Moses, and said, We have sinned, for we have
spoken against the LORD, and against thee; pray
unto the LORD, that he take away the serpents
from us. And Moses prayed for the people. And the
LORD said unto Moses, Make thee a fiery serpent,
and set it upon a pole: and it shall come to pass,
that every one that is bitten, when he looketh
upon it, shall live."
This Fiery serpent on the pole, now a rampantly
used symbol is hence interpreted as a direct
treatment of a particular ailment by some modern
Rod of Asclepius, Guinea worm
4. Symptoms of this condition include bruit,
progressive visual loss, pulsatile proptosis.
Patients usually present with sudden onset of
redness in an eye associated with progressive
proptosis.
Identify the vascular anatomical cause of these
symptoms.
Carotid-cavernous fistula
5. What is the rationale for
using diphenoxylate and
atropine together in
Lomotil for diarrhoea?
Atropine is subtherapeutic. This
combination is to ensure that if a
person tries to take the opioid in
excess, he’ll then have atropine side
effects.
6. Identify and differentiate between
the 2 disorders.
Gastroschisis and omphalocoele
respectively.
7. Why does
myopathy occur with
the use of statins?
Coenzyme Q is produced from
cholesterol, which is necessary in
the electron transport chain.
8. Increased activity can lead to muscle
cell hypertrophy which increases
contractility. Alternatively, inactivity can
lead to muscle cell atrophy and loss of
contractile strength. Comment on the
relative susceptibility of Type 1 fibres to
these processes compared to Type 2
fibres and explain why.
Type 1 are more susceptible to
atrophy and less to hypertrophy
compared to type 2 fibres
9.
Hint?
Hint
X, developed by David Ferruci, and named after
Thomas Watson, was original designed to answer
questions on Jeopardy!; winning the first million
dollar prize against the former winners in 2011In
2013, X’s team announced that its first commercial
application would be for utilisation management
decisions in Lung Cancer treatment at Memorial
Sloan Kettering Cancer Institute, New York City. 90%
of the nurses in the field now use X for guidance. X
has partnerships with several institutes, including the
Cleveland Clinic and Manipal Hospitals here in India.
IBM watson
Conne
ct.
• This round has 7 questions.
• Each question has three or four components
which are connected to each other in one
specific way.
• Pounce +15 for connect and +5 for
explanation, and -10 for wrong connect and
no negative for wrong explanation.
• Infinite bounce +15 for connect and +5 for
explanation. No negatives.
Charcot marie tooth disease
Syphilis
Clostridium
Wilson disease
Psammoma bodies
.
Cryptococcus neoformans
Chagas disease
Bidding
• There are 5 questions in this round.
• Each team gets 125 points to bid at the
beginning of the round.
• Five topics will be presented together before
the round starts.
• The topics are for a broad idea of what the
question will be.
• The teams have to allocate each topic certain
points, the total of which will be 125 or less.
• Say, the team allots X points to a particular
topic. They will get +X if they answer right,
Topics:
• Genetics
• Molecular Biology
• Physiology
• Epidemiology
• Pathology
Geneti
cs
Stanley Gartler was the first scientist to establish
clonality of human cancers. At a conference on
Cell Tissue and Organ Culture, he presented a
work in which he had found that 18 of the most
commonly used cell culture had a gene called
______ in common. This marker is common in
African Americans. The manifestations of
mutation in this gene are common in certain
countries because of their food habits. So, his
results implied that those 18 cell lines were
contaminated by the vigorously growing HeLa cell
line obtained from a black woman. His work was
Hint
G6PD
Molecular
biology
was a very important step towards higher
efficiency, because information can be stored
much more economically.
Another theory is that the Y Structure of
genes is a relic of the RNA world, a
hypothetical phase of the evolutionary history
of life on Earth, in which self-replicating RNA
molecules proliferated before the evolution of
DNA and proteins.
X creates smaller RNA molecules, which act as
functional ribozymes and membranes, from
the larger genomes enabling a self sufficient
RNA unit, without the initial necessity of
protein. X is also the reason why the
proteome is bigger than the genome. The
video shown has an item related to the
Lariat intron
Physiolog
y
Margination, rolling, adhesion
and diapedesis
Epidemiol
ogy
epidemic
curves, with
the x- axis
representing
time and y-axis
representing
number of
cases of a
particular
disease each.
What do these
graphs
Point source, and person to
person
Pathology
Apoptosis
Megaconn
ect
• There are 6 questions in the round.
• Each of the answers goes into a megaconnect.
• The teams can guess the megaconnect after every
question.
• All teams get to answer all questions.
• The scoring pattern is a differential one.
• The score for each question is 3n+5 where n is the number
of teams that get it wrong.
• There are no negatives for individual questions.
• The scoring for megaconnect is as follows-
• +60, -10; +50,-15; +40, -20; +30, -25; +20, - 30; +10, - 40
1. ABO incompatibility
mostly does not cause any
transfer of antibodies
across placenta but Rh
incompatibility does.
Polysaccharide
which is as follows. A protein X, allows yeast to
use ureidosuccinate in the presence of
ammonium ion. Chromosomal mutations in
the Y gene produces X. X depends for its
propagation on the Y product. Saccharomyces
cerevisiae strains cured of X were shown to
return to the X-carrying state without its
introduction from other cells. Overproduction
of Y increased the frequency with which a
strain became X by 100-fold.
This experiment acted as an independent
evidence for an ongoing controversy about the
existence of another protein during that time.
Prion
Astronauts experience diuresis in the
early stages of their stay in space. In
a research, one of their tissue
samples is found to contain a higher
level of cGMP. Explain the
mechanism of diuresis.
ANP
Carpal tunnel
Ramachandran plot
X
X
?
Multiple myeloma
And the megaconnect is….?
Amyloidosis
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Medillectuals Juniors Prelims Questions

  • 1. Medillectuals Juniors Researched by + QMs: Sneha, Srividya, Lajja, Dev (and also Satwik and Utkarsh  )
  • 2. Prelims 30 Questions 1 mark per question Some have Part points 1 minute per question
  • 4. 1. Alkaline phosphatase: gamma glutamyl transferase is the same as amylase : what?
  • 5. 2. During which stage(systole/diastole) of cardiac cycle is the blood flow to the right ventricle the highest?
  • 6. 3. Following is the ecg record of a patient with deviation in the mean axis. Predict whether it is left/right axis deviation and give the range(quadrant). Eg.0 to 90 degrees
  • 7. 4. With which metabolic pathways, do these polyketides share their biosynthesis?
  • 8. 5. A Journal of General Internal Medicine study, published in 2010, investigated medical errors from 1979 to 2006 in United States hospitals and found that medication errors increased 10% during the month of July , but not in neighbouring private hospitals. Surgical errors did not increase, leading to the hypothesis that medication errors are easier for new personnel to make because surgical procedures are done through team work. This study, though debunked by other studies gave rise to a popular myth, X. In UK, this has also been called Black Wednesday, or Killing season, after usage in a British medical drama series, Cardiac arrest. What is X?
  • 9. with the center as the ear canal and its base extending outwards along which our ear is incapable of determining the spatial source of the sound using only inter-aural time and intensity differences. How then are we still able to localise
  • 10. 7. Damage to which muscle and nerve is causing the gait shown in the video? (part points – 0.5 +0.5)
  • 11. 8. Why would a patient of Chronic Granulomatous Disease be more likely to suffer from infections due to Staphylococcus aureus?
  • 12. 9. Identify the tumor shown above. Prior to surgically removing this tumor, which class of drugs are to be used first? (Part points – 1 +1)
  • 13. 10.The following are a part of an exhaustive list. What is this list? 1. Essential fatty acid 2. Riboflavin 3. Biotin 4. Alcoholic extract of rice 5. Bioflavinoids
  • 14. 11. What does the above infographic represent?
  • 15. 12. ‘Whoonga’ is a drug cocktail smoked by individuals in South Africa. Among other drugs, this is said to contain antiretroviral medications which have been either stolen from those infected with HIV or sold by them on the black market. The predominant ARV in this drug cocktail has been found to have effects similar to LSD, sharing receptors in the brain. This results in it’s psychoactive effects, including hallucinations, vivid dreams and night terrors. Name the drug and the class it belongs to? (part points- 1+0.5)
  • 16. 13. In a child with egg, peanuts and pollen allergy, which common vaccine is contraindicated and why?
  • 17. 14. A Zinc smelter is brought to the casualty with vomiting and diarrhoea with rice water stools. O/E breath has garlicy odour. What is the most likely ECG finding?
  • 18. 15. Natalizumab is a monoclonal antibody used to treat multiple sclerosis and Crohn's disease. It acts as an antibody against molecules that reduces the ability of immune cells to cross the blood brain barrier and the intestinal wall. 1. What molecule does it target? 2. Which condition would a patient receiving this drug be more susceptible to? (part points- 1+1)
  • 19. 16. John Moore was a surveyor on the Alaska Pipeline who developed bleeding gums, bruising and an enlargement of the abdomen. He was diagnosed of ______ cancer. When they removed his spleen, it weighed 22 pounds whereas a normal spleen is just around 1 pound. The following laboratory values are found: WBC- 3,000/mm3 Platelets – 78,000/mm3 Neutrophils- 1600/mm3 Basophils-4/mm3 Eosinophils-60/mm3 His doctor, David Golde, without taking any consent from Moore, had filed a patent on Moore's cell line called Mo and its market value was estimated to be $3 billion. Moore filed a lawsuit against the doctor asking for his share. Identify the cancer.
  • 20. 17.Macular sparing i.e. loss of peripheral vision with intact macular vision occurs because the macular area in the cortex has dual arterial supply. Name and identify the arteries involved on an angiogram. A B C D
  • 21. 18.
  • 22. 19.Pituitary infarcts are rare but in women who have an episode of shock due to PPH, the pituitary become infarcted. Why are these women especially vulnerable to these infarcts?
  • 23. Time in hours 20.What does this graph represent? What do the red lines represent?
  • 24. 21. A woman has a regular menstrual cycle of 37 days duration. What is the duration of her follicular and luteal phases? Menstruation is for 4 days.
  • 25. Scientific American :'Surprisingly, even plants which use chlorophyll to absorb light energy can suffer from a condition analogous to X. The plant disease causes the leaves to blister, wither and die on exposure to sunlight. The process is so similar to the human condition X that some researchers hope to find a cure for the disease human condition by studying the properties of so called "vampire plants" like maize. ' Which
  • 26. 23.Why is the upstroke of pacemaker potential due to calcium channels and not fast sodium channels unlike myocyte potential or nerve potential?
  • 27. 24.Explain the reason behind the plateau in the venous function curve.
  • 28. 25.nAChRs: Varenicline Bupropion μ-opioid receptors: X and Y Give X and Y. (Part points 1 + 1)
  • 29. 1. What does X represent? 2. Name a drug used for the treatment of this condition (Part points 1 + 1) X 26.
  • 30. 27.
  • 31. 28. Ethacrynic Acid: Bartter syndrome Metolazone: X Identify X
  • 32. 29. A young male patient presented with severe renal colic. The observation made from urinalysis is shown in the image. 1. What is this finding? 2. What gastrointestinal pathology is he likely to have? (Part points will be
  • 33. including the head. They are caught with a particular kind of pots. These pots are like octopus real estate, and are attached to a long rope that is dropped into the water, where they eventually settle on the sea bottom. The unsuspecting octopus, who lives on the sea floor, comes along and says “Wow, a free house!” and, feeling like he has just won the lottery, sidles into his new abode, and is cooked up by the happy hunter. These pots have been made legendary in
  • 35.
  • 36. 1. Alkaline phosphatase: gamma glutamyl transferase is the same as amylase : what?
  • 38. 2. During which stage(systole/diastole) of cardiac cycle is the blood flow to the right ventricle the highest?
  • 40. 3. Following is the ecg record of a patient with deviation in the mean axis. Predict whether it is left/right axis deviation and give the range(quadrant). Eg.0 to 90 degrees
  • 42. 4. With which metabolic pathways, do these polyketides share their biosynthesis?
  • 44. 5. A Journal of General Internal Medicine study, published in 2010, investigated medical errors from 1979 to 2006 in United States hospitals and found that medication errors increased 10% during the month of July , but not in neighbouring private hospitals. Surgical errors did not increase, leading to the hypothesis that medication errors are easier for new personnel to make because surgical procedures are done through team work. This study, though debunked by other studies gave rise to a popular myth, X. In UK, this has also been called Black Wednesday, or Killing season, after usage in a British medical drama series, Cardiac arrest. What is X?
  • 45. July phenomenon – the time when new residents join.
  • 46. with the center as the ear canal and its base extending outwards along which our ear is incapable of determining the spatial source of the sound using only inter-aural time and intensity differences. How then are we still able to localise
  • 47. Shape of the pinna
  • 48. 7. Damage to which muscle and nerve is causing the gait shown in the video? (part points – 0.5 +0.5)
  • 49. Gluteus maximus, inferior gluteal nerve
  • 50. 8. Why would a patient of Chronic Granulomatous Disease be more likely to suffer from infections due to Staphylococcus aureus?
  • 52. 9. Identify the tumor shown above. Prior to surgically removing this tumor, which class of drugs are to be used first? (Part points – 1 +1)
  • 54. 10.The following are a part of an exhaustive list. What is this list? 1. Essential fatty acid 2. Riboflavin 3. Biotin 4. Alcoholic extract of rice 5. Bioflavinoids
  • 55. The missing vitamins between Vitamin E and K.
  • 56. 11. What does the above infographic represent?
  • 58. 12. ‘Whoonga’ is a drug cocktail smoked by individuals in South Africa. Among other drugs, this is said to contain antiretroviral medications which have been either stolen from those infected with HIV or sold by them on the black market. The predominant ARV in this drug cocktail has been found to have effects similar to LSD, sharing receptors in the brain. This results in it’s psychoactive effects, including
  • 60. 13. In a child with egg, peanuts and pollen allergy, which common vaccine is contraindicated and why?
  • 61. Influenza, yellow fever, because they are cultured in egg.
  • 62. 14. A Zinc smelter is brought to the casualty with vomiting and diarrhoea with rice water stools. O/E breath has garlicy odour. What is the most likely ECG finding?
  • 64. 15. Natalizumab is a monoclonal antibody used to treat multiple sclerosis and Crohn's disease. It acts as an antibody against molecules that reduces the ability of immune cells to cross the blood brain barrier and the intestinal wall. 1. What molecule does it target? 2. Which condition would a patient receiving this drug be more susceptible to? (part points- 1+1)
  • 66. 16. John Moore was a surveyor on the Alaska Pipeline who developed bleeding gums, bruising and an enlargement of the abdomen. He was diagnosed of ______ cancer. When they removed his spleen, it weighed 22 pounds whereas a normal spleen is just around 1 pound. The following laboratory values are found: WBC- 3,000/mm3 Platelets – 78,000/mm3 Neutrophils- 1600/mm3 Basophils-4/mm3 Eosinophils-60/mm3 His doctor, David Golde, without taking any consent from Moore, had filed a patent on Moore's cell line called Mo and its market value was estimated to be $3 billion. Moore
  • 68. 17.Macular sparing i.e. loss of peripheral vision with intact macular vision occurs because the macular area in the cortex has dual arterial supply. Name and identify the arteries involved on an angiogram. A B C D
  • 70. 18.
  • 72. 19.Pituitary infarcts are rare but in women who have an episode of shock due to PPH, the pituitary become infarcted. Why are these women especially vulnerable to these infarcts?
  • 73. The pituitary enlarges during pregnancy.
  • 74. Time in hours 20.What does this graph represent? What do the red lines represent?
  • 76. 21. A woman has a regular menstrual cycle of 37 days duration. What is the duration of her follicular and luteal phases? Menstruation is for 4 days.
  • 78. Scientific American :'Surprisingly, even plants which use chlorophyll to absorb light energy can suffer from a condition analogous to X. The plant disease causes the leaves to blister, wither and die on exposure to sunlight. The process is so similar to the human condition X that some researchers hope to find a cure for the disease human condition by studying the properties of so called "vampire plants" like maize. ' Which
  • 80. 23.Why is the upstroke of pacemaker potential due to calcium channels and not fast sodium channels unlike myocyte potential or nerve potential?
  • 81. The resting membrane potential of cardiac pacemaker cells is less negative. Hence, the sodium channels are in a permanently inactivated state.
  • 82. 24.Explain the reason behind the plateau in the venous function curve.
  • 83. Veins collapse at such low pressures
  • 84. 25.nAChRs: Varenicline and Bupropion μ-opioid receptors: X and Y Give X and Y. (Part points will be given)
  • 85. Partial agonist and antagonist. Hence, Buprenorphine and Naloxone/ naltrexone
  • 86. 1. What does X represent? 2. Name a drug used for the treatment of this condition (Part points will be given) X 26
  • 88. 27.
  • 90. 28. Ethacrynic Acid: Bartter syndrome Metolazone: X Identify X
  • 92. 29. A young male patient presented with severe renal colic. The observation made from urinalysis is shown in the image. 1. What is this finding? 2. What gastrointestinal pathology is he likely to have? (Part points will be
  • 93. Calcium oxalate crystals and crohn’s disease.
  • 94. including the head. They are caught with a particular kind of pots. These pots are like octopus real estate, and are attached to a long rope that is dropped into the water, where they eventually settle on the sea bottom. The unsuspecting octopus, who lives on the sea floor, comes along and says “Wow, a free house!” and, feeling like he has just won the lottery, sidles into his new abode, and is cooked up by the happy hunter. These pots have been made legendary in
  • 97. Crossword +5 for each, +10 Bonus for all correct
  • 99. 2. 5th generation cephalosporin
  • 100. walks into your hospital, which drug toxicity would he be assumed to have? P.S. he has a history of heart break, so treat him
  • 101. 9. Giant cells in measles ?
  • 102. 10. Erythromycin causes GI distress, above that of usual drugs, due to its action on?
  • 104. 12. In narcolepsy, there is decrease in CSF concentration of?
  • 105. Down.
  • 106. 1. Pringle’s manoeuvre is the clamping of which abdominal structure to prevent bleeding in the abdominal cavity?
  • 107. 3. Total Parenteral Nutrition induced cholelithiasis is due to decrease in _______.
  • 108. 5. The following viruses have the potential for reassortment: Arenavirus Orthomyxovirus Reovirus Complete the list.
  • 109. 6. Yawning is a withdrawal sign of?
  • 110. 7. What is this procedure called?
  • 111. 8. Syndrome of apparent mineralocorticoid excess, is due to inhibition of 11 beta hydroxy steroid dehydrogenase, due to intake of?
  • 112.
  • 113.
  • 114. Dry
  • 115. • There are 9 questions in this round. • Pounce +10, -5 • Infinite bounce +10, no negative
  • 116. 1. Expressing skepticism towards which emerging field?
  • 117.
  • 119. 2.
  • 120.
  • 121. Mermaid syndrome or sirenomelia- an extreme case of caudal regression syndrome
  • 122. “And the LORD sent fiery serpents among the people, and they bit the people; and much people of Israel died. Therefore the people came to Moses, and said, We have sinned, for we have spoken against the LORD, and against thee; pray unto the LORD, that he take away the serpents from us. And Moses prayed for the people. And the LORD said unto Moses, Make thee a fiery serpent, and set it upon a pole: and it shall come to pass, that every one that is bitten, when he looketh upon it, shall live." This Fiery serpent on the pole, now a rampantly used symbol is hence interpreted as a direct treatment of a particular ailment by some modern
  • 123.
  • 124. Rod of Asclepius, Guinea worm
  • 125. 4. Symptoms of this condition include bruit, progressive visual loss, pulsatile proptosis. Patients usually present with sudden onset of redness in an eye associated with progressive proptosis. Identify the vascular anatomical cause of these symptoms.
  • 126.
  • 128. 5. What is the rationale for using diphenoxylate and atropine together in Lomotil for diarrhoea?
  • 129.
  • 130. Atropine is subtherapeutic. This combination is to ensure that if a person tries to take the opioid in excess, he’ll then have atropine side effects.
  • 131. 6. Identify and differentiate between the 2 disorders.
  • 132.
  • 134. 7. Why does myopathy occur with the use of statins?
  • 135.
  • 136. Coenzyme Q is produced from cholesterol, which is necessary in the electron transport chain.
  • 137. 8. Increased activity can lead to muscle cell hypertrophy which increases contractility. Alternatively, inactivity can lead to muscle cell atrophy and loss of contractile strength. Comment on the relative susceptibility of Type 1 fibres to these processes compared to Type 2 fibres and explain why.
  • 138.
  • 139. Type 1 are more susceptible to atrophy and less to hypertrophy compared to type 2 fibres
  • 140. 9.
  • 141. Hint?
  • 142. Hint X, developed by David Ferruci, and named after Thomas Watson, was original designed to answer questions on Jeopardy!; winning the first million dollar prize against the former winners in 2011In 2013, X’s team announced that its first commercial application would be for utilisation management decisions in Lung Cancer treatment at Memorial Sloan Kettering Cancer Institute, New York City. 90% of the nurses in the field now use X for guidance. X has partnerships with several institutes, including the Cleveland Clinic and Manipal Hospitals here in India.
  • 143.
  • 146. • This round has 7 questions. • Each question has three or four components which are connected to each other in one specific way. • Pounce +15 for connect and +5 for explanation, and -10 for wrong connect and no negative for wrong explanation. • Infinite bounce +15 for connect and +5 for explanation. No negatives.
  • 147.
  • 148.
  • 150.
  • 151.
  • 153.
  • 154.
  • 156.
  • 157.
  • 159.
  • 160.
  • 162. .
  • 163.
  • 165.
  • 166.
  • 168.
  • 170. • There are 5 questions in this round. • Each team gets 125 points to bid at the beginning of the round. • Five topics will be presented together before the round starts. • The topics are for a broad idea of what the question will be. • The teams have to allocate each topic certain points, the total of which will be 125 or less. • Say, the team allots X points to a particular topic. They will get +X if they answer right,
  • 171. Topics: • Genetics • Molecular Biology • Physiology • Epidemiology • Pathology
  • 173. Stanley Gartler was the first scientist to establish clonality of human cancers. At a conference on Cell Tissue and Organ Culture, he presented a work in which he had found that 18 of the most commonly used cell culture had a gene called ______ in common. This marker is common in African Americans. The manifestations of mutation in this gene are common in certain countries because of their food habits. So, his results implied that those 18 cell lines were contaminated by the vigorously growing HeLa cell line obtained from a black woman. His work was
  • 174. Hint
  • 175.
  • 176. G6PD
  • 178. was a very important step towards higher efficiency, because information can be stored much more economically. Another theory is that the Y Structure of genes is a relic of the RNA world, a hypothetical phase of the evolutionary history of life on Earth, in which self-replicating RNA molecules proliferated before the evolution of DNA and proteins. X creates smaller RNA molecules, which act as functional ribozymes and membranes, from the larger genomes enabling a self sufficient RNA unit, without the initial necessity of protein. X is also the reason why the proteome is bigger than the genome. The video shown has an item related to the
  • 179.
  • 180.
  • 183.
  • 184.
  • 187. epidemic curves, with the x- axis representing time and y-axis representing number of cases of a particular disease each. What do these graphs
  • 188.
  • 189. Point source, and person to person
  • 191.
  • 192.
  • 194.
  • 195.
  • 197. • There are 6 questions in the round. • Each of the answers goes into a megaconnect. • The teams can guess the megaconnect after every question. • All teams get to answer all questions. • The scoring pattern is a differential one. • The score for each question is 3n+5 where n is the number of teams that get it wrong. • There are no negatives for individual questions. • The scoring for megaconnect is as follows- • +60, -10; +50,-15; +40, -20; +30, -25; +20, - 30; +10, - 40
  • 198. 1. ABO incompatibility mostly does not cause any transfer of antibodies across placenta but Rh incompatibility does.
  • 199.
  • 201. which is as follows. A protein X, allows yeast to use ureidosuccinate in the presence of ammonium ion. Chromosomal mutations in the Y gene produces X. X depends for its propagation on the Y product. Saccharomyces cerevisiae strains cured of X were shown to return to the X-carrying state without its introduction from other cells. Overproduction of Y increased the frequency with which a strain became X by 100-fold. This experiment acted as an independent evidence for an ongoing controversy about the existence of another protein during that time.
  • 202.
  • 203. Prion
  • 204. Astronauts experience diuresis in the early stages of their stay in space. In a research, one of their tissue samples is found to contain a higher level of cGMP. Explain the mechanism of diuresis.
  • 205.
  • 206. ANP
  • 207.
  • 208.
  • 210.
  • 211.
  • 213. X X ?
  • 214.

Notas do Editor

  1. Pathology easy out
  2. Prelims
  3. Final
  4. Prelims
  5. The blanks are not the same words.
  6. prelims
  7. prelim
  8. prelims
  9. Prelims
  10. prelims
  11. Finals
  12. Prelims star
  13. Pathology easy out
  14. Prelims
  15. Final
  16. Prelims
  17. The blanks are not the same words.
  18. prelims
  19. prelim
  20. prelims
  21. Prelims
  22. prelims
  23. Finals
  24. Prelims star
  25. Pharma easy
  26. Finals
  27. pop
  28. Accept if they say caduceus?
  29. Finals
  30. Final(?)
  31. Finals
  32. FInals
  33. Finals
  34. micro
  35. Finals
  36. Add more women.
  37. Biochem difficult
  38. Bi
  39. Immuno diff
  40. Correct this.