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BONE GRAFTS
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Project overview
What is graft  ? A viable  tissue that after removal from a donor site is implanted with in a recipient tissue is then restored repaired & regenerated. What is grafting ? Grafting is a procedure used to replace / restore missing bone or gum tissue.
What are bone grafts? Bone grafts are the materials used for replacement or augmentation of the bone.
[object Object],[object Object],[object Object]
Objectives & Rationale of Bone Grafts : ,[object Object],[object Object],[object Object]
Biologic concept of using Bone grafts ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Osteoinduction: Cell mediators at the defect (BMP) Stimulation of osteoprogenitor cells Osteoblasts New bone formation
Osteogenesis : Osteoblasts in the transplanted bone having adequate blood supply & cellular viablity. Forms new centers of ossification within the graft
Bone Grafts used in correction of  Periodontal Defects: ,[object Object],[object Object],[object Object],[object Object]
Autografts:   A tissue transferred from one position  to   another within the same individual . Allografts / Homografts:   Obtained from genetically dissimilar individual  of same species . Xenografts / Hetrografts:   Tissue transferred from one species to another species. Alloplasts:   A synthetic graft or inert foreign body implanted  into tissue.
[object Object],[object Object],[object Object],[object Object]
Autografts from intraoral site -Hegedus (1922) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bone Grafts harvested from intraoral sites are: ,[object Object],[object Object],[object Object],[object Object]
Osseous Coagulum: - (Robinson) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Bone Swaging: Technique requires existance of an edentulous area adjacent to the defect from which bone is pushed into contact with the root surface without fracturing the bone at its base.
Autografts from extraoral site ,[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Allografts: Allografts  used in the treatment of intrabony defects could be: ,[object Object],[object Object],[object Object],[object Object]
Freeze dried bone allografts (FDBA) ,[object Object],[object Object],[object Object],[object Object]
Decalcified Freeze dried bone allografts (DFDBA) -Urist(1965) ,[object Object],[object Object],[object Object],[object Object]
Frozen iliac crest marrow Need for cross – matching to decrease the likelihood of graft rejection as well as disease transmission  eliminate  the use of frozen iliac crest marrow.
Xenografts: Anorganic bovine bone (ABB) :  Bovine bone that has been chemically treated  with ehylenediamine to remove its organic components, leaving a trabecular & porous architecture similar to human bone.It is osteoconductive. Boplant:  Calf bone treated by detergent extraction, sterlized in propriolactone & freeze dried.
Kiel bone :  Calf / ox bone denaturated with  H2O2 (20%) dried with acetone & sterlized with etylene oxide. Ospurane:  Cow bone soaked in KOH , acetone & salt solution. Boiled bone:  Cow bone boiled or autoclaved.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Classification:   on the basis of  their ability to be resorbed as: Absorbable materials Nonabsorbable materials ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bioceramics:   Composed of CaPO4 with Ca & Po4 ratio  similar to bone Beta tricalcium phosphate:   Porous form of CaPo4 Hydroxyapetite:   Porous non resorbable Solid non resorbable or solid resorbable.
Polymers:   2 types 1) A non-resorbable , calcium hydroxide coated co- polymer of poly - methyl – methacrylate(PMMA). 2)  Poly – hydroxylethyl - methacrylate(PHEMA) / (HTR) Hard tissue replacement.
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Technique
Defect selection
[object Object],[object Object],[object Object],Preoperative preparation
Anesthesia Regional Anesthesia for patients comfort Local infilteration with epinephrin to facilitate hemostasis
A sulcular incision full thickness flap is reflected. A three wall intrabony defect is visualized at the distal of the first molar. Flap design
Defect or root debridement Rotary instrumentation using a multifluted surgical length bur on a high-speed handpiece is needed to gain access to the depth of the lesion and to plane the root surface, which is subsequently treated with citric acid (pH 1).
Graft management   The choice of graft material should be based on clinical considerations, including treatment objectives and potential patient morbidity.  If morbidity with graft procurement is a concern, an allograft of demineralized freeze-dried bone may be used. There are no reports of disease transmission, graft rejection or ankylosis after the use of demineralized freeze-dried bone allograft.
Placement of demineralized freeze-dried bone allograft is accomplished with light incremental pressure so  that the graft overfills the defect. The root surface has been treated with citric acid (pH 1) and the defect has been decorticated.
Flap closure  A monofilament suture is used to close the flaps by  primary closure.
Postoperative management/periodontal maintenance ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pre op Post op
 
Pre op Post op
Summary ,[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]

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Bone grafts

  • 2.
  • 3. What is graft ? A viable tissue that after removal from a donor site is implanted with in a recipient tissue is then restored repaired & regenerated. What is grafting ? Grafting is a procedure used to replace / restore missing bone or gum tissue.
  • 4. What are bone grafts? Bone grafts are the materials used for replacement or augmentation of the bone.
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  • 9. Osteoinduction: Cell mediators at the defect (BMP) Stimulation of osteoprogenitor cells Osteoblasts New bone formation
  • 10. Osteogenesis : Osteoblasts in the transplanted bone having adequate blood supply & cellular viablity. Forms new centers of ossification within the graft
  • 11.
  • 12. Autografts: A tissue transferred from one position to another within the same individual . Allografts / Homografts: Obtained from genetically dissimilar individual of same species . Xenografts / Hetrografts: Tissue transferred from one species to another species. Alloplasts: A synthetic graft or inert foreign body implanted into tissue.
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  • 18. Bone Swaging: Technique requires existance of an edentulous area adjacent to the defect from which bone is pushed into contact with the root surface without fracturing the bone at its base.
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  • 24. Frozen iliac crest marrow Need for cross – matching to decrease the likelihood of graft rejection as well as disease transmission eliminate the use of frozen iliac crest marrow.
  • 25. Xenografts: Anorganic bovine bone (ABB) : Bovine bone that has been chemically treated with ehylenediamine to remove its organic components, leaving a trabecular & porous architecture similar to human bone.It is osteoconductive. Boplant: Calf bone treated by detergent extraction, sterlized in propriolactone & freeze dried.
  • 26. Kiel bone : Calf / ox bone denaturated with H2O2 (20%) dried with acetone & sterlized with etylene oxide. Ospurane: Cow bone soaked in KOH , acetone & salt solution. Boiled bone: Cow bone boiled or autoclaved.
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  • 29. Bioceramics: Composed of CaPO4 with Ca & Po4 ratio similar to bone Beta tricalcium phosphate: Porous form of CaPo4 Hydroxyapetite: Porous non resorbable Solid non resorbable or solid resorbable.
  • 30. Polymers: 2 types 1) A non-resorbable , calcium hydroxide coated co- polymer of poly - methyl – methacrylate(PMMA). 2) Poly – hydroxylethyl - methacrylate(PHEMA) / (HTR) Hard tissue replacement.
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  • 35. Anesthesia Regional Anesthesia for patients comfort Local infilteration with epinephrin to facilitate hemostasis
  • 36. A sulcular incision full thickness flap is reflected. A three wall intrabony defect is visualized at the distal of the first molar. Flap design
  • 37. Defect or root debridement Rotary instrumentation using a multifluted surgical length bur on a high-speed handpiece is needed to gain access to the depth of the lesion and to plane the root surface, which is subsequently treated with citric acid (pH 1).
  • 38. Graft management The choice of graft material should be based on clinical considerations, including treatment objectives and potential patient morbidity. If morbidity with graft procurement is a concern, an allograft of demineralized freeze-dried bone may be used. There are no reports of disease transmission, graft rejection or ankylosis after the use of demineralized freeze-dried bone allograft.
  • 39. Placement of demineralized freeze-dried bone allograft is accomplished with light incremental pressure so that the graft overfills the defect. The root surface has been treated with citric acid (pH 1) and the defect has been decorticated.
  • 40. Flap closure A monofilament suture is used to close the flaps by primary closure.
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