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Atorvastatin- Cholesterol lowering drug
1. PRESENTATION ON ATORVASTATIN A LIPID LOWERING DRUG
Presented By:
Mr. Netra Prasad Neupane
Potential Employee of Sun Pharma
Presented To:
Managers of Sun Pharmaceuticals
Industries Ltd.
2. INTRODUCTION:
• ATORVASTATIN BELONGS TO THE CLASS OF STATIN, THESE DRUG
LOWERS THE BLOOD LIPID LEVEL AND DECREASES THE ILLNESS AND
DISORDERS.
• ATORVASTATIN NOT ONLY DEALS WITH THE LOWERING THE
CHOLESTEROL LEVEL BUT ALSO DEALS WITH CARDIOVASCULAR
DISEASES; DECREASE THE RISK ASSOCIATED STROKE AND HEART
DISEASES.
• THESE DRUGS MAY HELP STABILIZE THE PLAQUES ON BLOOD VESSEL
WALLS AND REDUCE THE RISK OF CERTAIN BLOOD CLOTS.
3. Dose of Atorvastatin
Atorvastatin normally prescribed as 10 to 20 mg O.D.
In moderate cases, 40 mg of Atorvastatin O.D.
For severe cases 80 mg of Atorvastatin is prescribed O.D.
4. Mechanism of Action:
Atorvastatin belongs to a class of drugs called HMG-CoA reductase inhibitors, or
statins. A class of drugs is a group of medications that work in a similar way.
These drugs are often used to treat similar conditions.
This drug works by lowering your low-density lipoprotein (LDL) or “bad”
cholesterol and raising your high-density lipoprotein (HDL) or “good”
cholesterol. Atorvastatin improves your body’s ability to get rid of LDL
cholesterol through your liver.
5. Side effects:
Cold symptoms such as runny nose, sneezing, and coughing
diarrhea
gas
heartburn
joint pain
forgetfulness
confusion
urinary tract infection (UTI)
6. Drug Interaction:
Atorvastatin oral tablet can interact with other medications, vitamins, or herbs;
1. Clarithromycin
2. Erythromycin
3. Itraconazole
4. Ketoconazole
5. Gemfibrozil
6. medications that contain fibrate
7. Contraindication:
Atorvastatin may cause serious allergy reaction such as;
1. swelling of your face, lips, tongue, or throat
2. Pregnancy
3. trouble breathing
4. trouble swallowing
8. Atorvastatin Brand present in Narayangarh
Based on my survey at different retailer (Sevangali Pharm, Miracle Pharmacy, Mukundasen Pharmacy) and hospital
pharmacy (NPI, Everest, Star Pharmacy) of the Narayangarh. Atorvastatin brand are as follows;
1. Aztor by Sun Pharma 9. AVS by G.D Laboratories
2. Atorlip by Cipla 10. Anzitor by Square Pharmaceuticals
3. Astat by Quest Pharmaceuticals 11. Atorbest by Biogain Remedies
4. Statin by Magnus Pharma
5. Avas
6. Atchol
7. Ator
8. Liplow
9. Highest selling brand- Statin
• MRP: 20.50 NPR for 20 mg tablets.
• Highly selling brand of 3 pharmacy among
6 pharmacy that I have surveyed.
• A product by Magnus Pharmaceuticals
• It comes in 10, 20 and 40 mg.
10. ATOR- second highest selling Brand
• MRP: 20.60 NPR for 20 mg tablets.
• Product of Nepal Pharmaceuticals.
• Comes in 10 mg and 20 mg.
11. Aztor:
• MRP: 20.60 NPR for 20 mg tablets.
• A product by Sun Pharmaceuticals.
• Comes in 5, 10, 20, 40 and 80 mg.
12. Avas:
• MRP: 20.60 NPR for 20 mg
tablets
• A product by Micro Labs Ltd.
• It comes in 5, 10, 20, 40,80 mg.
13. Atorlip:
• MRP: 20.59 NPR for 20 mg tablets.
• A product by Cipla Ltd.
• It comes in 5, 10, 20 mg.
14. Astat:
• MRP: 20.60 NPR for 20 mg of tablets
• A product of Quest Pharmaceuticals Pvt. Ltd.
• It comes in 5, 10, 20, 40 mg.
15. Liplow:
• MRP: 20.60 NPR for 20 mg of tablets.
• A product of Time Pharmaceuticals Pvt. Ltd.
• It comes in 5, 10 and 20 mg.
16. Atchol:
• MRP: 6.65 NPR for 20 mg of tablets.
• A product of Aristo Pharmaceuticals.
• It comes in 10 and 20 mg.
17. Conclusion:
My survey concluded that Statin and ATor are highly selling brand in different hospital of the
Narayangarh. Furthermore, Our Sun Pharma Aztor also comes among the top five highly selling brand.
In my survey, I found the Aristo drug cheaper as compare to other brand of Atorvastatin. Although, it is
one of the least selling drug in Narayangarh.
Moreover, Avas from Micro Labs and Aztor from Sun Pharmaceuticals comes in more dose range then
others brand of products.
In addition, Sun Pharmaceuticals can boost up Aztor easily as it has various dose ranges from slight
hyperlipidemic case (5 mg) to sever hyperlipidemic case (80 mg).