Human
Papillomavirus (HPV)
Presented By: NAZISH BAIG
(PMC – 02153020)
WHAT IS HPV?
• HPV stands for human papillomavirus. There
are lots of different types of HPV.
• Genital HPV is a very comm...
How many people are infected?
• Genital HPV infections are very common among
sexually active individuals.
• At any time, a...
How HVP looks like?
• Papillomaviruses are small, 52-55nm in
diameter.
• They are non-enveloped, icosahedra
particles.
• T...
HPV Transmission
• Direct skin-to-skin contact
– Usually, but not always sexual contact
• Infected birth canal
• Fomites (...
Testing & Treatment for
Genital Warts
• Can be detected in a clinical
exam;
– History
– Visual exam
– Pap smears
– DNA tes...
Human Papilloma Virus (HPV) Vaccine
 Two vaccines currently developed:
1. Gardasil – protects against HPV types 16, 18,
6...
Human papillomavirus (hpv)
Human papillomavirus (hpv)
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Human papillomavirus (hpv)

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Human Papillomavirus (HPV) is the most common genital virus in virology.

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Human papillomavirus (hpv)

  1. 1. Human Papillomavirus (HPV) Presented By: NAZISH BAIG (PMC – 02153020)
  2. 2. WHAT IS HPV? • HPV stands for human papillomavirus. There are lots of different types of HPV. • Genital HPV is a very common sexually transmitted infection. No symptoms • More than 100 types – More than 60 cutaneous types • Can lead to skin warts – 40 mucosal types • High risk – most common are HPV 16, 18, 45 and 31. • Low risk- include HPV types 6, 11. Cause ~70% of cervical cancersCause ~ 90% of anogenital warts
  3. 3. How many people are infected? • Genital HPV infections are very common among sexually active individuals. • At any time, about 20 million people have a genital HPV infection. • 74 percent of new infections occur among young people age 15–24
  4. 4. How HVP looks like? • Papillomaviruses are small, 52-55nm in diameter. • They are non-enveloped, icosahedra particles. • This shape is made up of 12 pentameric and 60 hexameric capsomers arranged on a T=7 lattice. • Their carpsid is composed of two proteins, a major (L1) and minor (L2).
  5. 5. HPV Transmission • Direct skin-to-skin contact – Usually, but not always sexual contact • Infected birth canal • Fomites (very rare)
  6. 6. Testing & Treatment for Genital Warts • Can be detected in a clinical exam; – History – Visual exam – Pap smears – DNA testing • Can be treated by removing the warts; • The virus cannot be removed, so the warts may grow back.
  7. 7. Human Papilloma Virus (HPV) Vaccine  Two vaccines currently developed: 1. Gardasil – protects against HPV types 16, 18, 6 and 11. 2. Cervarix – protects against HPV types 16 and 18.

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