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Hyperhidrosis Dee Anna Glaser, M.D. Associate Professor  Vice Chairman Department of Dermatology Saint Louis University
What is Hyperhidrosis? ,[object Object]
Sweating Nomenclature ,[object Object],[object Object],[object Object],[object Object],Multi-specialty Working Group on Recognition, Diagnosis, and Treatment of Primary Focal Hyperhidrosis, 2003.
Hyperhidrosis
Causes of  Generalized  Hyperhidrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Causes of  Localized  Hyperhidrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Idiopathic (Primary) Focal Hyperhidrosis
US Prevalence Survey mailed to a representative sample of 150,000 US households in January 2002 Prevalence of hyperhidrosis in the US is 2.8% (7.8 million individuals) 64% response rate Approximately 6,800 respondents with hyperhidrosis 32.4% of individuals with axillary hyperhidrosis ( 0.5% of the US population  or 1.3 million people) have sweating that is barely tolerable and frequently interferes with their daily activities, or is intolerable and always interferes with their daily activities (based on the HDSS).  Projected to the US population 50.8% have axillary hyperhidrosis: US prevalence is 1.4% (4 million individuals) Strutton DR, Kowalski JW, Glaser DA, Stang PE.  American Academy of Dermatology 61st Annual Meeting; March 21-26, 2003; San Francisco, Calif. Abstract P362.
Mean Age of Onset
Heredity/Genetics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ETS = Endoscopic Thoracic Sympathectomy
Diagnosis of Primary  Focal Hyperhidrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Multi-specialty Working Group on Recognition, Diagnosis, and Treatment of Primary Focal Hyperhidrosis, 2003.
Diagnostic Work-up ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Starch iodine test, with the darkened area  showing location of excessive sweating
Axillary Sweat Production 1 °  hyperhidrosis patients  healthy controls 346.0 Hund et al. Arch Derm 2002;138(4):539-41
DLQI Total Scores and Ranges by Dermatological Disease/Condition Diseases with DLQI Scores 10 or Greater ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Spalding et al. Value in Health 2003;6(3):242(abstract) Scores range from 0 to 30, with 30 indicating the worst quality of life.
Quality of life:  Primary Axillary Hyperhidrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Naumann et al. Brit J Derm 2002;147:1218-26
Quality of Life: Primary Palmar Hyperhidrosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Available Treatments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Response
Summary ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Hyperhidrosis Hyperhidrosis

  • 1. Hyperhidrosis Dee Anna Glaser, M.D. Associate Professor Vice Chairman Department of Dermatology Saint Louis University
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  • 8. US Prevalence Survey mailed to a representative sample of 150,000 US households in January 2002 Prevalence of hyperhidrosis in the US is 2.8% (7.8 million individuals) 64% response rate Approximately 6,800 respondents with hyperhidrosis 32.4% of individuals with axillary hyperhidrosis ( 0.5% of the US population or 1.3 million people) have sweating that is barely tolerable and frequently interferes with their daily activities, or is intolerable and always interferes with their daily activities (based on the HDSS). Projected to the US population 50.8% have axillary hyperhidrosis: US prevalence is 1.4% (4 million individuals) Strutton DR, Kowalski JW, Glaser DA, Stang PE. American Academy of Dermatology 61st Annual Meeting; March 21-26, 2003; San Francisco, Calif. Abstract P362.
  • 9. Mean Age of Onset
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  • 13. Axillary Sweat Production 1 ° hyperhidrosis patients healthy controls 346.0 Hund et al. Arch Derm 2002;138(4):539-41
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