1. Matthew Marquis3364 Woodland Way • Lafayette, California, 94549 • (925) 786-5608 • mmarquis@ucsc.edu
CAREER OBJECTIVE
To master a broad set of experimental techniques and acquire an in depth knowledge within the
biological sciences with the eventual goal of receiving a professorship. I hope to get deeply involved
in any project I am hired to help with so that I might make meaningful contributions to science as I
develop the skills to conduct my own research.
EDUCATION
University of California Santa Cruz Santa Cruz, California
College Eight September 2012-June
2016
Bachelor of Science, University Honors (Cum laude), 2016
Major: Biochemistry and Molecular Biology
Cumulative GPA: 3.82
AWARDS and HONORS
Doug Drexler Chemistry Scholarship (04/16/2015)
The Phi Beta Kappa National Honor Society
The Golden Key International Honour Society
RELEVENT COURSEWORK
Genetics
Organic Chemistry (2 quarters)
Organic Chemistry Laboratory (2 quarters)
Biochemistry (3 quarters)
Biochemistry Laboratory
Cell Biology
Eukaryotic Molecular Biology
Microbiology
Introduction to Neuroscience
Advanced Molecular Neuroscience
Quantum Chemistry
Thermodynamics
Macromolecular Structure
Undergraduate Research
Bioinformatics Programming
EXPERIENCE
University of California Santa Cruz, Santa Cruz, CA 02/15 - 06/16
Undergraduate laboratory
Research Advisor: Prof. Millhauser
 Prepared buffers for mammalian cell culture and Western blotting.
 Autoclaved pipette tips and solutions.
 Performed FMOC peptide syntheses.
 Quantified peptide/protein samples.

2.  Researched the solvent structures of human β-defensins 25 and 28 (peptides). The work
involved HPLC, mass spectrometry, and chemical modifications such as reduction, oxidative
folding, and protection group removal.
 Regular cleaning and maintenance of an electrospray ionization single quadrupole mass
spectrometer.
 Regular cleaning and maintenance of a Shimadzu analytical HPLC system.
University of California Santa Cruz, Santa Cruz, CA 2012-2015
UCSC Chemistry Club
Chief Tutor (volunteer)
 Tutored UCSC students in general and organic chemistry, privately or in group sessions, free
of charge. Approximately one group or individual tutoring session per week for 5 academic
quarters.
 Participated in regular fundraising events for the club.
 Helped in organizing and presenting at several science fairs hosted by the club at Westlake
and Bayview elementary schools. Demonstrated and explained examples of chemical
reactions or physical phenomena to ~200 children at each fair.
University California Santa Cruz, Santa Cruz, CA 09/15-12/15
UCSC Modified Supplemental Instruction
Learning Assistant
 Lead hour-long group study sessions of twelve or fewer students taking Chemistry 1A.
Sessions were three times per week.
 Tutored small groups (>4) of CHEM1A students twice per week in one hour sessions.
RESEARCH INTERESTS
The majority of my research thus far has been on the unusually structure-independent
binding interaction of human β-defensins to G-protein coupled receptors. From this, I have
developed strong interests in macromolecular structure and the nature of binding interfaces
between macromolecules. I am particularly interested in the binding of proteins to glycoproteins
because of its relevance to cell-cell recognition and immunity. Other members of my undergraduate
laboratory study the native structure of the prion protein, a glycoprotein famous for its role in
neurodegenerative diseases. I would like to research prions and other proteins that tend to
aggregate not just because of their importance to our health but also because they offer a chance to
understand fundamental aspects of protein folding and stability. Although I have mostly worked on
peptide structures, I am also very interested in catalytic RNAs, synapse structure, and the
connectivity of nerve cells in tissue. Of course, there are many other topics that I would like to
explore and at this point in my career I am more than happy to try new and unfamiliar fields.
LANGUAGES
English (fluent), Russian (1 year).
REFERENCES
Prof. Glenn L. Millhauser (831) 459-2176 glennm@ucsc.edu
Prof. Nikolaos Sgourakis (831) 459-3484 nsgourak@ucsc.edu
Dr. Michael Rexach mrexach@ucsc.edu