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THROMBOANGIITIS
OBLITERANS
(BUERGER’S DISEASE)
MITHRAAZ 2013 BATCH,
KILPAUK MEDICAL COLLEGE,
CHENNAI.
Name : Mr. Kannan
Age : 40 years
Sex: Male
Address: Tambaram
Occupation: Works in a fruit shop
Socio Economic Class: Upper Lower class
Chief Complaints :
Pain in the left leg for the past 2 years more for
the past 2 months
History of presenting illness
The patient was apparently normal 2 years back after which
he developed
PAIN – In his left leg
For 2 years more for the past 2 months
In the calf and foot region
INTERMITTENT - Brought about by walking
Cramping and Excruciating type of pain
Not radiating , Not referred
Aggravated on walking up stairs
Initially relieved on standing and now on rest
BOYD’S CLASSIFICATION – GRADE 3
OF INTERMITTENT CLAUDICATION
Claudication distance and progress of claudication
- Initially pain occurred only after 2 kilometers of
walking which gradually reduced and now pain
occurs if the patient walks 10 feet
No H/O rest pain
No H/O effect of warmth or cold on the pain
NO H/O suggestive of local causes of pain such as
trauma to the legs , swelling of legs , fever
No H/O tingling or numbness sensation
No H/O ulcers over the leg
No H/O blackish discolouration of any part of the
leg
No H/O suggestive of superficial phlebitis such
as pain , swelling , redness , cord like
thickenings along the course of veins
No H/O suggestive of Raynaud’s Phenomenon
such as attacks of pain , pallor ,bluish or dusky
red discolouration on exposure to cold
No H/O blackish discolouration of finger tips
after such attacks
No H/O suggestive of occlusive arterial
disease elsewhere in the body :
No H/O Chest pain , palpitations,
breathlessness
No H/O Black outs , loss of consciousness,
weakness of limbs
No H/O Blurring of vision
No H/O Abdominal pain
No H/O Impotence
Past history
- For the past 2 years , the patient has been visiting
private clinics and has taken native medications but
symptoms did not resolve
- No H/O similar complaints in the past
- No H/O diabetes mellitus , hypertension , tuberculosis
asthma ,epilepsy ,jaundice
- No H/O Cardiac diseases , cerebrovascular accidents ,
hyperlipidemia, collagen diseases
- No H/O previous hospitalisation /surgery
Personal history
- Patient consumes non-vegetarian diet
- Normal bowel and bladder habits
- H/O Smoking from the age of 13 years
No of years of smoking : 27 years
Smokes 3 packets of cigarettes per day
SMOKING INDEX : 810
PACK YEARS INDEX : 81
- H/O Alcohol consumption for the past 1 year
180 ml per day
- No H/O drug abuse
Allergy history
No H/O allergy to any food or drugs
Family History
No H/O Similar complaints in the family
No H/O suggestive of atherosclerosis in the
family
Summary
A 40 year old male ,who is a chronic smoker
presented with complaints of excruciating pain
in calf and foot during walking which is relieved
by rest of BOYD’S GRADE 3 with history
suggestive of progressive claudication .
The probable diagnosis is peripheral vascular
disease involving femoral , popliteal , tibial
arteries .
General examination
After getting consent from the patient , the general
examination was done.
Conscious, oriented, moderately built and nourished
No pallor
No icterus
No cyanosis
GRADE 1 clubbing present
No pedal edema
No generalised lymphadenopathy
SIGNS OF ATHEROSCLEROSIS – NO Arcus senilus , no
transverse ear crease , no xanthomas
Vital signs
Pulse rate : 82 /min , regular in rhythm ,normal in
volume and character , no vessel wall thickening , no
radioradial/radiofemoral delay
Dorsalis pedis , posterior tibial and popliteal
pulsations absent in the left lower limb
Respiratory rate : 16/min , abdominothoracic
Blood pressure : 110 /70 mm hg measured in left
upper arm in sitting posture
Patient is afebrile
Examination Of Lower Limbs
After explaining the procedure and getting
consent , patient was exposed from mid thigh
and examination was done under bright light
INSPECTION – patient in supine posture with both the legs
kept side by side
Attitude : the limbs are extended at both hip and knee joint
No deformity present
Muscle wasting present in the calf region in left leg
No redness , swelling along the course of superficial veins
NO COLOUR CHANGE VISIBLE
Examination of lower limbs
Signs of peripheral ischemia : present in left limb
-There is diminished hair over the left limb - calf
-Thinning of skin present
-There is Loss of subcutaneous fat
-Shininess present
-Trophic changes in nail : brittle nail present
-No ulceration in pressure areas like heel , malleoli , ball of
foot , tip of toes
A scar of 5 x 4 cm is present over the inner aspect of calf in
the right leg, scar is healthy – history suggested as silencer
burn
Left
Right
Tests on inspection
GUTTERING OF VEINS : present on elevation of the limbs
BUERGER’S POSTURAL TEST : was not able to appreciate the
pallor and pink appearance as the patient was dark skinned
CAPILLARY FILLING TIME :was not able to appreciate the
pallor and pink appearance as the patient was dark skinned
VENOUS REFILLING : in the left lower limb veins collapsed at
30 degree and refilling was slower when compared to the
right side
EXAMINATION OF LOWER LIMBS
NO GANGRENE OR ULCER PRESENT OVER BOTH
THE LOWER LIMBS
PALPATION
Skin temperature : skin is warm over both the
lower limbs except for the left foot which is cold
No tenderness present
No swelling ,tenderness , cord like
thickening of veins
Tests on palpation
Capillary refilling :
There was delay in the time taken for blanched toe of left
lower limb to turn pink when compared with the right side
Venous refilling (harvey’s sign):
Refilling of vein segment slow in the left lower limb when
compared to the right side
Crossed leg test ( FUCHSIG’S TEST ) : was not well
appreciable
Examination of Peripheral pulses
RIGHT LEFT
Superficial temporal artery ++ ++
Carotid artery ++ ++
Brachial artery ++ ++
Radial artery ++ ++
Femoral artery ++ +
Popliteal artery ++ -
Posterior tibial artery ++ -
Dorsalis pedis + -
Examination Of Joints
Movements of Right Left
Interphalangeal joint N N
Metatarsophalangeal joint N N
Ankle joint N N
Knee joint N N
Hip joint N N
Examination of nerves
MOTOR RIGHT LEFT
Bulk (Calf ) 31cm 28cm
Tone normal normal
Power 5/5 5/5
Reflexes normal normal
Plantar response flexion flexion
SENSORY
Crude / fine touch + +
Pain + +
Temperature + +
Vibration + +
Examination of lymph nodes
Inguinal lymph nodes are not enlarged
Auscultation
No bruit
No murmurs
Reactive hyperemia test :
To be done
Systemic examination
Respiratory system :
Normal vesicular breath sounds heard . No added
sounds
Cardiovascular system :
S1 S2 heard . No murmurs
Central nervous system :
No focal neurological deficit
Abdomen :
Soft , non tender , no organomegaly , no free fluid ,
hernial orifices free , external genitalia normal
Spine and cranium : normal
Diagnosis
Compensatory Peripheral vascular disease of
left lower limb in the form of Thromoangiitis
Obliterans (Buerger’s disease) with probably
Femoropopliteal occlusion ( type 3)without any
complications .
Differential diagnosis :
Atherosclerosis
Vasculitis
Management
Investigations
Baseline: Complete blood count – TC , DC , ESR
Hb% , blood grouping and typing ,BT,CT
Blood sugar , urea , serum creatinine
Urine routine : albumin ,sugar,deposits
X ray chest , ECG
Serology : HIV , VDRL , HBsAg
Specific investigations
-Blood sugar : fasting , post prandial , HbA1C
-LIPID PROFILE
-Anti nuclear Ab , Anti Phospholipid Ab,
homocysteine levels
-DOPPLER ultrasound
-DUPLEX SCAN
-Angiography
-BROWN’S VASOMOTOR INDEX
Treatment
Non surgical methods
SMOKING ABSTINENCE
MEDICAL MANAGEMENT
ANALGESICS-Tramadol-50mg TID
Ketorolac-20mg TID
PENTOXYFILLIN-400mg TID
Used to treat intermittent claudication.
Improves blood flow through the peripheral blood vessels by
increasing flexibility of RBC, decreasing platelet aggregation
and thrombus formation, reduces blood viscosity.
Beurger’s position
Beurger’s exercise
Heel raise : to decrease load on calf
muscles
TAO.pptx

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TAO.pptx

  • 1. THROMBOANGIITIS OBLITERANS (BUERGER’S DISEASE) MITHRAAZ 2013 BATCH, KILPAUK MEDICAL COLLEGE, CHENNAI.
  • 2. Name : Mr. Kannan Age : 40 years Sex: Male Address: Tambaram Occupation: Works in a fruit shop Socio Economic Class: Upper Lower class Chief Complaints : Pain in the left leg for the past 2 years more for the past 2 months
  • 3. History of presenting illness The patient was apparently normal 2 years back after which he developed PAIN – In his left leg For 2 years more for the past 2 months In the calf and foot region INTERMITTENT - Brought about by walking Cramping and Excruciating type of pain Not radiating , Not referred Aggravated on walking up stairs Initially relieved on standing and now on rest BOYD’S CLASSIFICATION – GRADE 3 OF INTERMITTENT CLAUDICATION
  • 4. Claudication distance and progress of claudication - Initially pain occurred only after 2 kilometers of walking which gradually reduced and now pain occurs if the patient walks 10 feet No H/O rest pain No H/O effect of warmth or cold on the pain NO H/O suggestive of local causes of pain such as trauma to the legs , swelling of legs , fever No H/O tingling or numbness sensation No H/O ulcers over the leg No H/O blackish discolouration of any part of the leg
  • 5. No H/O suggestive of superficial phlebitis such as pain , swelling , redness , cord like thickenings along the course of veins No H/O suggestive of Raynaud’s Phenomenon such as attacks of pain , pallor ,bluish or dusky red discolouration on exposure to cold No H/O blackish discolouration of finger tips after such attacks
  • 6. No H/O suggestive of occlusive arterial disease elsewhere in the body : No H/O Chest pain , palpitations, breathlessness No H/O Black outs , loss of consciousness, weakness of limbs No H/O Blurring of vision No H/O Abdominal pain No H/O Impotence
  • 7. Past history - For the past 2 years , the patient has been visiting private clinics and has taken native medications but symptoms did not resolve - No H/O similar complaints in the past - No H/O diabetes mellitus , hypertension , tuberculosis asthma ,epilepsy ,jaundice - No H/O Cardiac diseases , cerebrovascular accidents , hyperlipidemia, collagen diseases - No H/O previous hospitalisation /surgery
  • 8. Personal history - Patient consumes non-vegetarian diet - Normal bowel and bladder habits - H/O Smoking from the age of 13 years No of years of smoking : 27 years Smokes 3 packets of cigarettes per day SMOKING INDEX : 810 PACK YEARS INDEX : 81 - H/O Alcohol consumption for the past 1 year 180 ml per day - No H/O drug abuse
  • 9. Allergy history No H/O allergy to any food or drugs Family History No H/O Similar complaints in the family No H/O suggestive of atherosclerosis in the family
  • 10. Summary A 40 year old male ,who is a chronic smoker presented with complaints of excruciating pain in calf and foot during walking which is relieved by rest of BOYD’S GRADE 3 with history suggestive of progressive claudication . The probable diagnosis is peripheral vascular disease involving femoral , popliteal , tibial arteries .
  • 11. General examination After getting consent from the patient , the general examination was done. Conscious, oriented, moderately built and nourished No pallor No icterus No cyanosis GRADE 1 clubbing present No pedal edema No generalised lymphadenopathy SIGNS OF ATHEROSCLEROSIS – NO Arcus senilus , no transverse ear crease , no xanthomas
  • 12. Vital signs Pulse rate : 82 /min , regular in rhythm ,normal in volume and character , no vessel wall thickening , no radioradial/radiofemoral delay Dorsalis pedis , posterior tibial and popliteal pulsations absent in the left lower limb Respiratory rate : 16/min , abdominothoracic Blood pressure : 110 /70 mm hg measured in left upper arm in sitting posture Patient is afebrile
  • 13. Examination Of Lower Limbs After explaining the procedure and getting consent , patient was exposed from mid thigh and examination was done under bright light INSPECTION – patient in supine posture with both the legs kept side by side Attitude : the limbs are extended at both hip and knee joint No deformity present Muscle wasting present in the calf region in left leg No redness , swelling along the course of superficial veins NO COLOUR CHANGE VISIBLE
  • 14. Examination of lower limbs Signs of peripheral ischemia : present in left limb -There is diminished hair over the left limb - calf -Thinning of skin present -There is Loss of subcutaneous fat -Shininess present -Trophic changes in nail : brittle nail present -No ulceration in pressure areas like heel , malleoli , ball of foot , tip of toes A scar of 5 x 4 cm is present over the inner aspect of calf in the right leg, scar is healthy – history suggested as silencer burn
  • 15. Left
  • 16. Right
  • 17. Tests on inspection GUTTERING OF VEINS : present on elevation of the limbs BUERGER’S POSTURAL TEST : was not able to appreciate the pallor and pink appearance as the patient was dark skinned CAPILLARY FILLING TIME :was not able to appreciate the pallor and pink appearance as the patient was dark skinned VENOUS REFILLING : in the left lower limb veins collapsed at 30 degree and refilling was slower when compared to the right side
  • 18. EXAMINATION OF LOWER LIMBS NO GANGRENE OR ULCER PRESENT OVER BOTH THE LOWER LIMBS PALPATION Skin temperature : skin is warm over both the lower limbs except for the left foot which is cold No tenderness present No swelling ,tenderness , cord like thickening of veins
  • 19. Tests on palpation Capillary refilling : There was delay in the time taken for blanched toe of left lower limb to turn pink when compared with the right side Venous refilling (harvey’s sign): Refilling of vein segment slow in the left lower limb when compared to the right side Crossed leg test ( FUCHSIG’S TEST ) : was not well appreciable
  • 20. Examination of Peripheral pulses RIGHT LEFT Superficial temporal artery ++ ++ Carotid artery ++ ++ Brachial artery ++ ++ Radial artery ++ ++ Femoral artery ++ + Popliteal artery ++ - Posterior tibial artery ++ - Dorsalis pedis + -
  • 21. Examination Of Joints Movements of Right Left Interphalangeal joint N N Metatarsophalangeal joint N N Ankle joint N N Knee joint N N Hip joint N N
  • 22. Examination of nerves MOTOR RIGHT LEFT Bulk (Calf ) 31cm 28cm Tone normal normal Power 5/5 5/5 Reflexes normal normal Plantar response flexion flexion SENSORY Crude / fine touch + + Pain + + Temperature + + Vibration + +
  • 23. Examination of lymph nodes Inguinal lymph nodes are not enlarged
  • 24. Auscultation No bruit No murmurs Reactive hyperemia test : To be done
  • 25. Systemic examination Respiratory system : Normal vesicular breath sounds heard . No added sounds Cardiovascular system : S1 S2 heard . No murmurs Central nervous system : No focal neurological deficit Abdomen : Soft , non tender , no organomegaly , no free fluid , hernial orifices free , external genitalia normal Spine and cranium : normal
  • 26. Diagnosis Compensatory Peripheral vascular disease of left lower limb in the form of Thromoangiitis Obliterans (Buerger’s disease) with probably Femoropopliteal occlusion ( type 3)without any complications . Differential diagnosis : Atherosclerosis Vasculitis
  • 27. Management Investigations Baseline: Complete blood count – TC , DC , ESR Hb% , blood grouping and typing ,BT,CT Blood sugar , urea , serum creatinine Urine routine : albumin ,sugar,deposits X ray chest , ECG Serology : HIV , VDRL , HBsAg
  • 28. Specific investigations -Blood sugar : fasting , post prandial , HbA1C -LIPID PROFILE -Anti nuclear Ab , Anti Phospholipid Ab, homocysteine levels -DOPPLER ultrasound -DUPLEX SCAN -Angiography -BROWN’S VASOMOTOR INDEX
  • 29. Treatment Non surgical methods SMOKING ABSTINENCE MEDICAL MANAGEMENT ANALGESICS-Tramadol-50mg TID Ketorolac-20mg TID PENTOXYFILLIN-400mg TID Used to treat intermittent claudication. Improves blood flow through the peripheral blood vessels by increasing flexibility of RBC, decreasing platelet aggregation and thrombus formation, reduces blood viscosity.
  • 30. Beurger’s position Beurger’s exercise Heel raise : to decrease load on calf muscles