1. Subject: PHARMACEUTICAL
ENGINEERING-Theory
VACCUM DISTILLATION
PREPARED BY: KASHISH WILSON
ASSISTANT PROFESSOR,
MM SCHOOL OF PHARMACY,
MM UNIVERSITY,
SADOPUR , AMBALA

2. Contents:
Introduction & basic principles and
methodology of
1. Distillation under reduced pressure/VACCUM
DISTILLATION

3. Introduction
 Distillation is a process in which a liquid or vapour mixture of two
or more substances is separated into its component fractions of
desired purity, by the application and removal of heat.
 Principle:
Separation of components from a liquid mixture via distillation
depends on the differences in boiling points of the individual
components. And also depends on the vapour pressure characteristics
of liquid mixtures.

4. Distillation under reduced
pressure/Vaccum Distillation
 Vacuum distillation is a method of
distillation whereby the pressure
above the liquid mixture to be
distilled is reduced to less than its
vapor pressure
 This distillation method works on the
principle that boiling occurs when the
vapor pressure of a liquid exceeds the
ambient pressure
 It is use for temperature sensitive
materials like oil industry.

5. Thank You