2. Impacts, Issues
Open or Close the Stem Cell Factories?
Only embryonic stem cells can differentiate into
any specialized cell in the body; engineered
stem cells are not yet safe for humans
3. Homeostasis in Animals
Body parts must interact to perform many tasks
• Coordinate and control individual parts
• Acquire and distribute raw materials to cells and
dispose of wastes
• Protect tissues against injury or attack
• Reproduce, nourish and protect offspring through
early growth and development
• Maintain the internal environment (homeostasis)
4. 32.1 Organization of Animal Bodies
Tissue
• Interacting cells and extracellular substances that
carry out one or more specialized tasks
Organ
• Structural unit of two or more tissues organized in
a specific way to carry out specific tasks
Organ systems
• Two or more organs and other components
interacting in a common task
5. Animal Cells are United by Cell Junctions
Tight junctions
• Prevent fluid from seeping between epithelial
cells; fluid must pass through cells
Adhering junctions
• Hold cells together at distinct spots
Gap junctions
• Permit ions and small molecules to pass from
cytoplasm of one cell to another
6. 32.1 Key Concepts
Animal Organization
All animals are multicelled, with cells joined by
cell junctions
Typically, cells are organized in four tissue
types: epithelial tissue, connective tissue,
muscle tissue, and nervous tissue
Organs, which consist of a combination of
tissues, interact in organ systems
7. 32.2 Epithelial Tissue
Epithelium (epithelial tissue)
• A sheet of cells that covers the body’s outer
surface and lines its internal ducts and cavities
Basement membrane
• A secreted extracellular matrix that attaches the
epithelium to the underlying tissue
Microvilli
• Fingerlike projections of absorptive epithelia
14. Simple cuboidal epithelium
• Lines kidney tubules, ducts
of some glands, oviducts
• Functions in absorption an
secretion, movement of materials
Fig. 32-4b, p. 541
16. Simple columnar epithelium mucus-secreting gland cell
• Lines some airways, parts
of the gut
• Functions in absorption and
secretion, protection
Fig. 32-4c, p. 541
17. Glandular Epithelium
Glands
• Organs that release substances onto the skin, or
into a body cavity or interstitial fluid
Exocrine glands (glands with ducts)
• Deliver secretions to an external or internal
surface (saliva, milk, earwax, digestive enzymes)
Endocrine glands (no ducts)
• Secrete hormones which are carried in blood
18. 32.3 Connective Tissues
Connective tissues consist of cells and the
extracellular matrix they secrete
Connective tissues connect body parts and
provide structural and functional support to other
body tissues
19. Soft Connective Tissues
Loose connective tissue
• Fibroblasts secrete a matrix of complex
carbohydrates with fibers dispersed widely
through the matrix
Dense connective tissue (dense collagen fibers)
• Dense irregular: Supports skin, internal organs
• Dense regular: Ligaments and tendons
20. Specialized Connective Tissues
Cartilage: Rubbery extracellular matrix,
supports and cushions bones
Adipose tissue: Fat filled cells, stores energy,
cushions and protect organs
Bone: Rigid support, muscle attachment,
protection, mineral storage, blood production
33. 32.4 Muscle Tissues
Muscle tissue is made up of cells that contract
when stimulated, requires ATP energy
34. Three Types of Muscle Tissues
Skeletal muscle tissue
• Moves the skeleton (voluntary)
• Long, striated cells with many nuclei
Cardiac muscle tissue
• Heart muscle (involuntary)
• Striated cells with single nuclei
Smooth muscle tissue
• In walls of hollow organs (involuntary)
• No striations, single nuclei
35. 32.5 Nervous Tissue
Nervous tissue
• Consists of specialized signaling cells (neurons)
and cells that support them (neuroglial cells)
Nervous tissue detects internal and external
stimuli, and coordinates responses to stimuli
36. Neurons
Neurons
• Excitable cells with long cytoplasmic extensions
• Send and receive electrochemical signals
Three types of neurons
• Sensory neurons are excited by specific stimuli
• Interneurons integrate sensory information
• Motor neurons relay commands from brain and
spinal cord to muscles and glands
39. 32.2-32.5 Key Concepts
Types of Animal Tissues
Epithelial tissue covers the body’s surface and
lines its internal tubes
Connective tissue provides support and
connects body parts
Muscle tissue moves the body and its parts
Nervous tissue detects internal and external
stimuli and coordinates responses
40. 32.6 Overview of Major Organ Systems
In vertebrates, organs arise from three
embryonic germ layers
• Ectoderm (outermost layer) forms nervous tissue
and epithelium of skin
• Mesoderm (middle layer) forms muscle,
connective tissue, and lining of body cavities
• Endoderm (innermost layer) forms epithelium of
gut and lungs
46. SUPERIOR
(of two body parts, distal (farthest from
the one closer to head) trunk or from origin
of a body part)
frontal
plane midsagittal proximal (closest
plane to trunk or to
(aqua) (green)
point of origin of
a body part)
ANTERIOR
(at or near
front of
POSTERIOR
body)
(at or near
back of body)
transverse
plane
INFERIOR (yellow)
(of two body parts,
the one farthest from head) Fig. 32-11c, p. 546
51. Integumentary Nervous Muscular Skeletal Circulatory Endocrine
System System System System System System
Protects body Detects external Moves body Supports and Rapidly Hormonally
from injury, and internal and its internal protects body transports controls body
dehydration, and stimuli; controls parts; parts; provides many materials functioning;
some pathogens; and coordinates maintains muscle to and from with nervous
controls its responses to posture; attachment interstitial fluid system
temperature; stimuli; generates heat sites; produces and cells; helps integrates short-
excretes certain integrates all by increases red blood cells; stabilize and long-term
wastes; receives organ system in metabolic stores calcium, internal pH and activities. (Male
some external activities. activity. phosphorus. temperature. testes added.)
stimuli. Fig. 32-12a, p. 547
52. Lymphatic System Respiratory System Digestive System Urinary System Reproductive System
Collects and Rapidly delivers Ingests food and Maintains the Female: Produces eggs;
returns some oxygen to the water; volume and after fertilization, affords
tissue fluid to tissue fluid that mechanically, composition a protected, nutritive
the bloodstream; bathes all living chemically breaks of internal environment for the
defends the body cells; removes down food and environment; development of new
against infection carbon dioxide absorbs small excretes excess individuals. Male:
and tissue wastes of cells; molecules into fluid and Produces and transfers
damage. helps regulate internal bloodborne sperm to the female.
pH. environment; wastes. Hormones of both
eliminates food systems also influence
residues. other organ systems.
Fig. 32-12b, p. 547
54. 32.6 Key Concepts
Organ Systems
Vertebrate organ systems compartmentalize the
tasks of survival and reproduction for the body
as a whole
Different systems arise from ectoderm,
mesoderm, and endoderm, the primary tissue
layers that form in the early embryo
55. 32.7 Vertebrate Skin—
Example of an Organ System
Skin is the body’s interface with the environment
• Sensory receptors, barrier against pathogens,
internal temperature control, water conservation
Vertebrate skin is made up of all four tissue
types arranged in two layers:
• Outer epidermis contain keratinocytes
• Deeper dermis contains nerves, blood and lymph
vessels, hair follicles and glands
67. Sunlight and Human Skin
Melanocytes in skin make a brown pigment
(melanin) which affects skin color and tanning
Melanin protects against UV radiation
• A little UV promotes vitamin D production
• A lot of UV damages DNA and promotes cancer
68. 32.8 Farming Skin
Commercially grown skin substitutes are already
in use for treatment of chronic wounds
Skin may be a source of stem cells that could be
used to grow other organs
69. 32.7-32.8 Key Concepts
A Closer Look at Skin
Skin is an example of an organ system
It includes epithelial layers, connective tissue,
adipose tissue, glands, blood vessels, and
sensory receptors
It helps protect the body, conserve water, control
temperature, excrete wastes, and detect
external stimuli
Figure 32.3 Generalized structure of a simple epithelium.
Figure 32.4 Micrographs and drawings of three types of simple epithelia in vertebrates, with examples of their functions and locations.
Figure 32.4 Micrographs and drawings of three types of simple epithelia in vertebrates, with examples of their functions and locations.
Figure 32.4 Micrographs and drawings of three types of simple epithelia in vertebrates, with examples of their functions and locations.
Figure 32.4 Micrographs and drawings of three types of simple epithelia in vertebrates, with examples of their functions and locations.
Figure 32.4 Micrographs and drawings of three types of simple epithelia in vertebrates, with examples of their functions and locations.
Figure 32.5 Micrographs and drawings of connective tissues.
Figure 32.5 Micrographs and drawings of connective tissues.
Figure 32.5 Micrographs and drawings of connective tissues.
Figure 32.5 Micrographs and drawings of connective tissues.
Figure 32.5 Micrographs and drawings of connective tissues.
Figure 32.5 Micrographs and drawings of connective tissues.
Figure 32.6 Locations of cartilage and bone tissue. Spongy bone tissue has hard parts with spaces between. Compact bone tissue is more dense. The bone shown here is the femur, the largest and strongest bone in the human body.
Figure 32.7 Cellular components of human blood. Cells and cell fragments (platelets) drift along in plasma, the fluid portion of the blood. Plasma consists of water with dissolved proteins, salts, and nutrients.
Figure 32.11 ( a ) Main body cavities in humans. ( b , c ) Directional terms and planes of symmetry for the body. For vertebrates that keep their main body axis parallel with Earth’s surface, dorsal refers to the upper surface (back) and ventral to the lower surface. For upright walkers, anterior (the front) corresponds to ventral and posterior (the back) to dorsal.
Figure 32.11 ( a ) Main body cavities in humans. ( b , c ) Directional terms and planes of symmetry for the body. For vertebrates that keep their main body axis parallel with Earth’s surface, dorsal refers to the upper surface (back) and ventral to the lower surface. For upright walkers, anterior (the front) corresponds to ventral and posterior (the back) to dorsal.
Figure 32.11 ( a ) Main body cavities in humans. ( b , c ) Directional terms and planes of symmetry for the body. For vertebrates that keep their main body axis parallel with Earth’s surface, dorsal refers to the upper surface (back) and ventral to the lower surface. For upright walkers, anterior (the front) corresponds to ventral and posterior (the back) to dorsal.
Figure 32.12 H uman organ systems and their functions.
Figure 32.12 H uman organ systems and their functions.
Figure 32.13 ( a ) Skin structure. ( b ) Section through human skin. ( c ) Structure of a hair. It arises from a hair follicle derived from epidermal cells that have sunk into the dermis. Figure It Out: How many polypeptide chains are in a keratin macrofibril? Answer: Three
Figure 32.13 ( a ) Skin structure. ( b ) Section through human skin. ( c ) Structure of a hair. It arises from a hair follicle derived from epidermal cells that have sunk into the dermis. Figure It Out: How many polypeptide chains are in a keratin macrofibril? Answer: Three
Figure 32.13 ( a ) Skin structure. ( b ) Section through human skin. ( c ) Structure of a hair. It arises from a hair follicle derived from epidermal cells that have sunk into the dermis. Figure It Out: How many polypeptide chains are in a keratin macrofibril? Answer: Three
Figure 32.14 Skin of a frog ( Dendrobates azureus ). The dermis contains epidermally derived glands that secrete mucus and poison. Pigment cells in the dermis give the frog its distinctive color and warn predators that it is poisonous.
Figure 32.14 Skin of a frog ( Dendrobates azureus ). The dermis contains epidermally derived glands that secrete mucus and poison. Pigment cells in the dermis give the frog its distinctive color and warn predators that it is poisonous.