2. The FluidVision® A-IOL Advantage
2PowerVision │ FluidVision® IOL
First true shape changing, fluid-driven IOL
Mimics eye’s natural accommodative process
Creates a continuously variable monofocal
Designed to restore True AccommodationTM
Proven in over 140 patients with excellent
visual outcomes
Now introducing a new “leapfrog” product

3. How the FluidVision Lens Works
• When the eye moves to its natural accommodated
state, the capsular bag squeezes a tiny amount of
fluid (less than a drop) from the haptics at the
periphery of the A-IOL into the center
• This inflates the lens, giving near vision
• When the eye attempts to move to its
disaccommodated state, the capsular bag squeezes
fluid the other way
• This deflates the lens, giving far vision
3PowerVision │ FluidVision® IOL

4. Summary of Clinical Studies
4PowerVision │ FluidVision® IOL
Sighted Eyes
(monocular)
Single Center Pilot
Enrollment completed 2013
4.0 mm
incision device
26 eyes
Sighted Eyes
(binocular)
Single Center Pilot
Enrollment completed 2015
4.0 mm
incision device,
pre-loaded injector
8 eyes
Sighted Eyes
(monocular)
Multi Center
Enrollment completed 2014
4.0 mm
incision device,
pre-loaded injector
67 eyes
Sighted Eyes
(monocular)
Multi Center
Enrollment completed 2015
3.5 mm
incision device,
pre-loaded injector
50 eyes

5. 5PowerVision │ FluidVision® IOL
Busting the Myth
Intracapsular implantation of an
accommodating IOL will result
in loss of function over time
MYTH FACT
The FluidVision accommodating IOL achieves
stable results in the capsular bag over time
• Stable, excellent visual outcomes and continued
accommodative function out to 24 months
• Design keeps anterior and posterior leaflets
apart, creating an open capsule
• Rabbit studies confirm lack of capsular reaction*
• Capsule is the ideal location for an IOL
* J. Kohl, et al., J Cat Refract Surgery 2014 v40 p2113-2119

6. Proven Excellent, Stable Outcomes
6PowerVision │ FluidVision® IOL

7. Defocus Curve
Binocular Subject, 5D
-0.3
-0.2
-0.1
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
-3-2.5-2-1.5-1-0.500.511.52
logMAR
Defocus (D)
66 cm 40 cm
(20/40)
(20/20)
(20/25)
Proven Subjective Accommodation
Average subjective accommodation (monocular) = 3.5D*
PowerVision │ FluidVision® IOL 7
* Average subjective accommodation based on 6 month results, Single Center Pilot

8. Objective Accommodation by Autorefractor
Monocular Subject, 2.5D
Proven Objective Accommodation
Average objective accommodation = 1.4D*
PowerVision │ FluidVision® IOL 8
* Average objective accommodation based on 6 month results, Multi Center CE (monocular)

9. No Compromise in Visual Quality
9PowerVision │ FluidVision® IOL
0.00
0.50
1.00
1.50
2.00
2.50
3CPD 6CPD 9CPD 12CPD
logCS
MesopicCS
Monofocal (Tecnis) Tecnis MF
Rezoom Restor
FluidVision(M12)
MonofocalFluidVision
0.00
0.50
1.00
1.50
2.00
2.50
w/ glare
3CPD
w/ glare
6CPD
w/ glare
9CPD
w/ glare
12CPD
logCS
MesopicGlare CS
Monofocal (Tecnis) Tecnis MF
Rezoom Restor
FluidVision(M12)
Multifocal IOLsMultifocalIOLs
FluidVision lens overlaid on published data from Gil et al Comparison of far and near contrast sensitivity in patients
symmetrically implanted with multifocal and monofocal IOLs. Eur J Ophthalmol 2014; 24(1):44-52

10. Now Imagine If…
10PowerVision │ FluidVision® IOL
PowerVision
Itself
Reinvented

11. Leapfrog current product technology
 Increase near visual acuity to 20/20*
 Achieve 20/20* across all distances
 Expected in the clinic in H1 2016
Introducing the FluidVision 20/20TM
11PowerVision │ FluidVision® IOL
FluidVision
FluidVision 20/20
* Approximate binocular target

12. We’ll Never Stop Reinventing Ourselves
12PowerVision │ FluidVision® IOL
3.5 mm
incision
Near visual
acuity to
20/20
2.8 mm
incision
Post implant
adjustment
Toric
FluidVision 20/20