This is part of our in-house training programme where I had presented this.

1. Solvents in the pharmaceutical use & The Green chemistry

3. List of class II solvents The Solvent levels should to be screened through the chromatographic method & Quantified in the Final API

4. Genotoxic carcinogens Carcinogens which are produces cancer by the affecting the genes are or chromosomes Nurotoxicity The ability of a substance to cause adverse effect on the nervous system PDE: Abbreviation for permitted daily exposure

5. LIST OF CLASS III SOLVENTS Since the solvents are class-III the accepted limit is LOD NMT 0.5% in Final API .No need of the chromatographic method or Quantification.

6. Class II solvent for which no toxicological data available . Due to the non availability of the toxicological data the manufacturer should give the Justification for the usage & the residual solvent levels of the above solvents in the final API.

22. GREEN ROUTES FOR THE SYNTHESIS OF THE COMMON CHEMICALS

26. IONIC LIQUIDES

27. Enantioseletive robinson annulation Solvent free Reaction

28. Neat reactant Witting olifination

29. Pyridenes synthesis

30. Synthesis of the 3-coumarins

31. Chemoseletive aldol condensation

51. Conclusion Green chemistry Not a solution to all environmental problems But the most fundamental approach to preventing pollution.

52. Thank you