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Dr. Aditya Agrawal
Consultant Chest Physician
Bhatia Hospital
SMOKING & IT’S ILL
EFFECTS
• Formerly regarded solely as a “lifestyle choice.”
• Smoking is now recognized as a chronic, relapsing
disorder caused because of addiction.
• It has become the leading preventable cause of
mortality and morbidity over the years.
Am J Med (2008)121 (4A), S1–S2Am J Med (2008)121 (4A), S1–S2
Smoking – An epidemic
Tobacco
TRADITIONAL COMMERCIAL
 Smoked in a pipe for
ceremonial purposes
 Used as an offering to a
healer, elder or other person
as a sign of respect or thanks
 Medicinal tobacco was often
used as a painkiller
 Deliberate targeting of
specific consumer groups
 Premeditated and conscious
addition of chemicals that
lead to addiction
 Scarcely contains actual
tobacco
4
Nicotine:
10-19
seconds to
reach brain
ADDICTION
Approx 50 LAKHS people die from tobacco use every
year
(1 death every 6 seconds)
Tobacco kills up to half of its users.
WHO report, 2011
• India has about 12 crore smokers & it is ever increasing
• 32.7% of adult males and 1.4% of adult females
• 17% of males and 9% of females in 13-15 yrs age group use
tobacco.
• Smoking currently causes approx 8-10 lakh deaths per year in
India.
WHO report on the global tobacco epidemic, 2008
N Engl J Med 2008;358:1137-47.
How big is the problem of
smoking in India
Tobacco-Related Health Risks
Cancer
Respiratory
 Asthma
 Bronchitis
 COPD
 Emphysema
Cardiovascular
Aortic
aneurysm
Cardiovascular
disease
Stroke
Sudden cardiac
death
Tobacco-Related Health Risks
Tobacco-Related Health Risks
Reproductive
•Miscarriage/
•spontaneous
abortion
•Premature baby
•Reduced fertility
Endocrine
•Early
menopause
•Irregular
menstrual
bleeding
•Premature
wrinkling and
aging
Neonatology
•Lower birth
weight
•Sudden infant
death syndrome
(SIDS)
Tobacco-Related Health Risks
Infections
•Pneumonia
•Influenza
•Opportunistic
respiratory infections
Others
•Accidents
•Delayed wound
healing
WHO report on the global tobacco epidemic, 2008
THERE IS
AN EASIER WAY
OF COMMITTING SUICIDE
Smokeless Tobacco in India
• Only 20% of the total tobacco consumed in India is in
the form of cigarettes
• About 40% consume bidis and the remaining 40%
chew tobacco, pan masala, snuff, gutkha, masheri
and tobacco toothpaste.
• These products contain putrefied tobacco, paraffin,
areca nut, lime, catechu, and 230 permitted additives
and flavours including known carcinogens.
• India has one of the highest rates of oral cancer in the
world
• Leading cause of oral cancer, oral mucosal fibrosis,
periodontal disease, abrasion of teeth & bad
breath.
1) http://www.cpaaindia.org/activities/projects.
2) WHO
3) Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109:857-864)
Can smoking affect vision?
• Smoking is as bad for your eyes as it is for
the rest of your body. Research has linked
smoking to an increased risk of
developing age-related macular
degeneration, cataract, and optic nerve
damage, all of which can lead to
blindness.
How does smoking affect bones?
• Recent studies show a direct relationship between tobacco use and decreased bone
density.
• Smoking is one of many factors—including weight, alcohol consumption, and activity
level—that increase your risk for osteoporosis
• Significant bone loss has been found in older women and men who smoke. Quitting
smoking appears to reduce the risk for low bone mass and fractures.
• In addition, smoking from an early age puts women at even higher risk for
osteoporosis. Smoking lowers the level of the hormone estrogen in your body, which
can cause menopause earlier, boosting the risk for osteoporosis.
How does smoking affect heart
and blood vessels?
• The chemicals in tobacco smoke harm your blood cells and damage the function of
your heart. This damage increases your risk for:
• Atherosclerosis,
• Aneurysms
• Cardiovascular disease (CVD), which includes:
– Coronary heart disease (CHD), narrow or blocked arteries around the heart
– Heart attack and damage to your arteries
– Heart-related chest pain
– High blood pressure
• Peripheral arterial disease (PAD)
• Stroke, which is sudden death of brain cells caused by blood clots or bleeding
How does smoking affect lungs
and breathing?
Smoking causes:
•Chronic obstructive pulmonary disease (COPD)
•Emphysema
•Chronic bronchitis
•Pneumonia
•Asthma
•Tuberculosis
Exposing an infant to
second-hand smoke
greatly increases the
child’s risk of:
• asthma
• pneumonia
• bronchitis
• fluid in the
middle ear
Each year, second-hand tobacco smoke is
responsible for thousands of:
• deaths from heart disease in adults
• deaths from lung cancer in adults
• deaths from other cancers in adults
• cases of lung infections, such as pneumonia
and bronchitis, in infants and young children
• Infertility, spontaneous abortion, and low birth
weight babies
Second-hand Tobacco Smoke
The Consequences of Second-hand
Tobacco Smoke on Health
Effects Causally Associated with Second-hand Smoke Exposure
Developmental Effects
Foetal growth: low birth weight or small for gestational age
Sudden infant death syndrome (SIDS)
Respiratory Effects
Acute lower respiratory tract infections in children (bronchitis,
pneumonia)
Asthma induction and exacerbation in children
Chronic respiratory symptoms in children
Eye and nasal irritation in adults
Middle ear infections in children
The Consequences of Second-hand
Tobacco Smoke on Health
Effects Causally Associated with Second-hand Smoke
Exposure (cont.)
Carcinogenic Effects
Lung cancer
Nasal sinus cancer
Cardiovascular Effects
Heart disease mortality
Acute and chronic coronary heart disease morbidity
The Consequences of Second-hand
Tobacco Smoke on Health
Effects With Suggestive Evidence of a
Causal Association With Second-hand Smoke Exposure
Developmental Effects
Spontaneous abortion
Adverse impact on cognition and behavior
Respiratory Effects
Exacerbation of cystic fibrosis
Decreased pulmonary function
Carcinogenic Effects
Cervical cancer
When Smokers Quit
Risks from Environmental
Tobacco Smoke (ETS)
– Mainstream—smoke drawn through tobacco while
inhaling
– Sidestream—smoke from the burning end of a
cigarette or smoke exhaled by a smoker
– Contains 2 times more tar and nicotine, 5 times
more carbon monoxide, and 50 times more
ammonia than mainstream smoke
– Causes more deaths a year than any other
environmental pollutant
The Wrinkles
The Lie The Truth
A smoker’s risk of
heart attack is more
than twice that of
nonsmokers.
Cigarette smoking is
the biggest risk factor
for sudden cardiac
death.
Smoking and Strokes
• Cigarette smoking doubles the risk of a stroke.
• Smoking damages the cardiovascular system.
• Cigarette smoke makes clotting more likely.
• Smoking cessation today would significantly cut
risk of stroke within two years.
Smoking & Reproduction
• Women smokers have greater risks of:
– Primary and secondary infertility
– Miscarriage and premature delivery
– Stillbirth, neonatal deaths, and sudden infant death
syndrome (SIDS)
– Danger to the mother, eg, bleeding
– Menstrual problems
– Premature menopause + osteoporosis
Women who plan to have children need
to know that smoking is associated with:
• Reduced fertility
• Early menopause
• Increased likelihood of delayed pregnancy
• Complications of pregnancy
• Reduced oxygen to placenta
Women
who take
birth
control pills
and smoke
are:
39 times more
likely to have a
heart attack
22 times more
likely to suffer
from certain
forms of stroke
EFFECTS OF TOBACCO ON HEALTH
Tobacco affects all parts of the body from head to toe
Skin Premature aging
Skin creasing and
Skin cancers
Teeth Staining
Wearing off of teeth
Receding gum line
Mouth Oral cancer
Submucosal fobrosis
Vocal cords Cancer
Eyes Visual problems – cataracts, premature
blindness
Brain Addiction
Strokes
Brain hemorrhage
Heart Heart attacks
Aneurysms
Sudden death
Blood vessels Hardening and bloackage
leading to gangrene
Lungs Chronic bronchitis
Emphysema
Infections
Chronic obstructive lung
disease
Cancer
Bladder/ Kidney Cancer
Male impotence
Esophagus/ stomach/ pancreas Cancer
Reproductive system Male impotence
Female infertility
Abortions
Premature birth
Osteoporosis
Bones Thining and risk of fractures
Is smoking a risk factor for
autoimmune diseases?
• Smoking compromises the immune system, making smokers more likely to have
respiratory infections.
• Smoking also causes several autoimmune diseases, including Crohn’s disease and
rheumatoid arthritis.
• It may also play a role in periodic flare-ups of signs and symptoms of autoimmune
diseases.
• Smoking doubles your risk of developing rheumatoid arthritis.
• Smoking has recently been linked to type 2 diabetes, also known as adult-onset
diabetes. Smokers are 30% to 40% more likely to develop type 2 diabetes than
nonsmokers.
DEPARTMENT OF PULMONARY
MEDICINE

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Smoking and It's Ill Effects by Dr. Aditya Agrawal

  • 1.
  • 2. Dr. Aditya Agrawal Consultant Chest Physician Bhatia Hospital SMOKING & IT’S ILL EFFECTS
  • 3. • Formerly regarded solely as a “lifestyle choice.” • Smoking is now recognized as a chronic, relapsing disorder caused because of addiction. • It has become the leading preventable cause of mortality and morbidity over the years. Am J Med (2008)121 (4A), S1–S2Am J Med (2008)121 (4A), S1–S2 Smoking – An epidemic
  • 4. Tobacco TRADITIONAL COMMERCIAL  Smoked in a pipe for ceremonial purposes  Used as an offering to a healer, elder or other person as a sign of respect or thanks  Medicinal tobacco was often used as a painkiller  Deliberate targeting of specific consumer groups  Premeditated and conscious addition of chemicals that lead to addiction  Scarcely contains actual tobacco 4
  • 6.
  • 7. Approx 50 LAKHS people die from tobacco use every year (1 death every 6 seconds) Tobacco kills up to half of its users. WHO report, 2011
  • 8. • India has about 12 crore smokers & it is ever increasing • 32.7% of adult males and 1.4% of adult females • 17% of males and 9% of females in 13-15 yrs age group use tobacco. • Smoking currently causes approx 8-10 lakh deaths per year in India. WHO report on the global tobacco epidemic, 2008 N Engl J Med 2008;358:1137-47. How big is the problem of smoking in India
  • 10. Respiratory  Asthma  Bronchitis  COPD  Emphysema Cardiovascular Aortic aneurysm Cardiovascular disease Stroke Sudden cardiac death Tobacco-Related Health Risks
  • 11. Tobacco-Related Health Risks Reproductive •Miscarriage/ •spontaneous abortion •Premature baby •Reduced fertility Endocrine •Early menopause •Irregular menstrual bleeding •Premature wrinkling and aging Neonatology •Lower birth weight •Sudden infant death syndrome (SIDS)
  • 13. WHO report on the global tobacco epidemic, 2008
  • 14. THERE IS AN EASIER WAY OF COMMITTING SUICIDE
  • 15. Smokeless Tobacco in India • Only 20% of the total tobacco consumed in India is in the form of cigarettes • About 40% consume bidis and the remaining 40% chew tobacco, pan masala, snuff, gutkha, masheri and tobacco toothpaste. • These products contain putrefied tobacco, paraffin, areca nut, lime, catechu, and 230 permitted additives and flavours including known carcinogens. • India has one of the highest rates of oral cancer in the world • Leading cause of oral cancer, oral mucosal fibrosis, periodontal disease, abrasion of teeth & bad breath. 1) http://www.cpaaindia.org/activities/projects. 2) WHO 3) Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109:857-864)
  • 16.
  • 17.
  • 18. Can smoking affect vision? • Smoking is as bad for your eyes as it is for the rest of your body. Research has linked smoking to an increased risk of developing age-related macular degeneration, cataract, and optic nerve damage, all of which can lead to blindness.
  • 19. How does smoking affect bones? • Recent studies show a direct relationship between tobacco use and decreased bone density. • Smoking is one of many factors—including weight, alcohol consumption, and activity level—that increase your risk for osteoporosis • Significant bone loss has been found in older women and men who smoke. Quitting smoking appears to reduce the risk for low bone mass and fractures. • In addition, smoking from an early age puts women at even higher risk for osteoporosis. Smoking lowers the level of the hormone estrogen in your body, which can cause menopause earlier, boosting the risk for osteoporosis.
  • 20. How does smoking affect heart and blood vessels? • The chemicals in tobacco smoke harm your blood cells and damage the function of your heart. This damage increases your risk for: • Atherosclerosis, • Aneurysms • Cardiovascular disease (CVD), which includes: – Coronary heart disease (CHD), narrow or blocked arteries around the heart – Heart attack and damage to your arteries – Heart-related chest pain – High blood pressure • Peripheral arterial disease (PAD) • Stroke, which is sudden death of brain cells caused by blood clots or bleeding
  • 21. How does smoking affect lungs and breathing? Smoking causes: •Chronic obstructive pulmonary disease (COPD) •Emphysema •Chronic bronchitis •Pneumonia •Asthma •Tuberculosis
  • 22. Exposing an infant to second-hand smoke greatly increases the child’s risk of: • asthma • pneumonia • bronchitis • fluid in the middle ear
  • 23. Each year, second-hand tobacco smoke is responsible for thousands of: • deaths from heart disease in adults • deaths from lung cancer in adults • deaths from other cancers in adults • cases of lung infections, such as pneumonia and bronchitis, in infants and young children • Infertility, spontaneous abortion, and low birth weight babies Second-hand Tobacco Smoke
  • 24. The Consequences of Second-hand Tobacco Smoke on Health Effects Causally Associated with Second-hand Smoke Exposure Developmental Effects Foetal growth: low birth weight or small for gestational age Sudden infant death syndrome (SIDS) Respiratory Effects Acute lower respiratory tract infections in children (bronchitis, pneumonia) Asthma induction and exacerbation in children Chronic respiratory symptoms in children Eye and nasal irritation in adults Middle ear infections in children
  • 25. The Consequences of Second-hand Tobacco Smoke on Health Effects Causally Associated with Second-hand Smoke Exposure (cont.) Carcinogenic Effects Lung cancer Nasal sinus cancer Cardiovascular Effects Heart disease mortality Acute and chronic coronary heart disease morbidity
  • 26. The Consequences of Second-hand Tobacco Smoke on Health Effects With Suggestive Evidence of a Causal Association With Second-hand Smoke Exposure Developmental Effects Spontaneous abortion Adverse impact on cognition and behavior Respiratory Effects Exacerbation of cystic fibrosis Decreased pulmonary function Carcinogenic Effects Cervical cancer
  • 27.
  • 28.
  • 30. Risks from Environmental Tobacco Smoke (ETS) – Mainstream—smoke drawn through tobacco while inhaling – Sidestream—smoke from the burning end of a cigarette or smoke exhaled by a smoker – Contains 2 times more tar and nicotine, 5 times more carbon monoxide, and 50 times more ammonia than mainstream smoke – Causes more deaths a year than any other environmental pollutant
  • 31. The Wrinkles The Lie The Truth
  • 32. A smoker’s risk of heart attack is more than twice that of nonsmokers. Cigarette smoking is the biggest risk factor for sudden cardiac death.
  • 33. Smoking and Strokes • Cigarette smoking doubles the risk of a stroke. • Smoking damages the cardiovascular system. • Cigarette smoke makes clotting more likely. • Smoking cessation today would significantly cut risk of stroke within two years.
  • 34. Smoking & Reproduction • Women smokers have greater risks of: – Primary and secondary infertility – Miscarriage and premature delivery – Stillbirth, neonatal deaths, and sudden infant death syndrome (SIDS) – Danger to the mother, eg, bleeding – Menstrual problems – Premature menopause + osteoporosis
  • 35.
  • 36. Women who plan to have children need to know that smoking is associated with: • Reduced fertility • Early menopause • Increased likelihood of delayed pregnancy • Complications of pregnancy • Reduced oxygen to placenta
  • 37. Women who take birth control pills and smoke are: 39 times more likely to have a heart attack 22 times more likely to suffer from certain forms of stroke
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45. EFFECTS OF TOBACCO ON HEALTH Tobacco affects all parts of the body from head to toe Skin Premature aging Skin creasing and Skin cancers Teeth Staining Wearing off of teeth Receding gum line Mouth Oral cancer Submucosal fobrosis Vocal cords Cancer Eyes Visual problems – cataracts, premature blindness Brain Addiction Strokes Brain hemorrhage Heart Heart attacks Aneurysms Sudden death
  • 46. Blood vessels Hardening and bloackage leading to gangrene Lungs Chronic bronchitis Emphysema Infections Chronic obstructive lung disease Cancer Bladder/ Kidney Cancer Male impotence Esophagus/ stomach/ pancreas Cancer Reproductive system Male impotence Female infertility Abortions Premature birth Osteoporosis Bones Thining and risk of fractures
  • 47. Is smoking a risk factor for autoimmune diseases? • Smoking compromises the immune system, making smokers more likely to have respiratory infections. • Smoking also causes several autoimmune diseases, including Crohn’s disease and rheumatoid arthritis. • It may also play a role in periodic flare-ups of signs and symptoms of autoimmune diseases. • Smoking doubles your risk of developing rheumatoid arthritis. • Smoking has recently been linked to type 2 diabetes, also known as adult-onset diabetes. Smokers are 30% to 40% more likely to develop type 2 diabetes than nonsmokers.

Editor's Notes

  1. •Tobacco contains nicotine, which is highly addictive. •When a smoker takes a puff, it takes only 10-19 seconds for the effects of the nicotine to reach the brain – that’s faster than that uptake of heroin or cocaine. In fact, many drug addicts say they would rather give up heroin or cocaine than cigarettes. Source: American Academy of Pediatrics 1997; Smoking Cessation: Clinical Practice Guideline Number 18. Agency for Health Care Policy and Research, Centers for Disease Control and Prevention, April 1996.
  2. This list of health risks is compiled from data from the World Health Organization, American Cancer Society, the American Lung Association, the National Cancer Institute, The Heart Association, the US Centers for Disease Control and Prevention, and from various studies undertaken in Asia.
  3. This list of health risks is compiled from data from the World Health Organization, American Cancer Society, the American Lung Association, the National Cancer Institute, The Heart Association, the US Centers for Disease Control and Prevention, and from various studies undertaken in Asia.
  4. Sources: International Consultation on Environmental Tobacco Smoke (ETS) and Child Health. WHO/NCD/TFI//99.10. World health Organization, Geneva, Switzerland, 11-14 January 1999. Things You Should Know About ETS, American Academy of Pediatrics, 1997; CDC Office on Smoking and Health 1999.
  5. International Consultation on Environmental Tobacco Smoke (ETS) and Child Health. WHO/NCD/TFI//99.10. World health Organization, Geneva, Switzerland, 11‑14 January 1999. Source: National Cancer Institute. Health Effects of Exposure to Environmental Tobacco Smoke: The Report of the California Environmental Protection Agency. Smoking and Tobacco Control Monograph No. 10. Bethesda, MD. U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, NIH Pub. No. 99-4645, 1999.
  6. International Consultation on Environmental Tobacco Smoke (ETS) and Child Health. WHO/NCD/TFI//99.10. World health Organization, Geneva, Switzerland, 11‑14 January 1999. Source: National Cancer Institute. Health Effects of Exposure to Environmental Tobacco Smoke: The Report of the California Environmental Protection Agency. Smoking and Tobacco Control Monograph No. 10. Bethesda, MD. U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, NIH Pub. No. 99-4645, 1999.
  7. International Consultation on Environmental Tobacco Smoke (ETS) and Child Health. WHO/NCD/TFI//99.10. World health Organization, Geneva, Switzerland, 11‑14 January 1999. Source: National Cancer Institute. Health Effects of Exposure to Environmental Tobacco Smoke: The Report of the California Environmental Protection Agency. Smoking and Tobacco Control Monograph No. 10. Bethesda, MD. U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, NIH Pub. No. 99-4645, 1999.
  8. •The Association of Reproductive Health Professionals issued guidelines for prescribing oral contraceptives to smokers. They suggest that the choice of oral contraceptives should be tailored to a woman’s age and how much she smokes. Women over 35 years of age who smoke heavily (15 or more cigarettes a day) should be categorically denied oral contraceptives unless they quit, because of the risks involved. Castelli WP. Reducing risk in OC users who smoke. Contemp Ob Gyn 1996; 41:118-126.