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Response Scientific®, Inc. is a growth stage company that has developed a patented microencapsulation technology named Aegis Fluidics™ that "shields and protects" the contents of our microcapsules including Rx drugs, Rx medical foods, and nutraceuticals in liquid form, from damaging stomach acids and enzymatic degradation. Protein and peptide derived drugs and nutraceuticals are particularly subject to this damage.
Bioavailability Breakthrough Superior Delivery To BloodstreamAegis Microfluidics capsules Deliver Contents ByDiffusion* The Aegis Microcapsules travel through the stomach to the small intestines virtually unharmed by stomach acids or enzymatic actions. Diffusion of the contents of the microcapsules begins upon entry to the small intestines and continues through the digestive tract releasing contents along the way. Approximately 60% of the contents are emptied in the first 60 minutes. Diffusion and Concentration Gradients The passage of the microcapsules through the intestines is dependent on the concentration gradients. A concentration gradient exists whenever a concentrated solution is in contact with a less concentrated solution. Because the solutions are in contact, particles may flow between the two solutions by the process known as diffusion. Diffusion is a term used to describe the mixing of two different substances that are placed in contact. Diffusion is the migrating of these different particles. Although particles move in every direction, there is a net flow from the more concentrated solution to the less concentrated solution. As the number of particles in the more concentrated solution diminishes and the number of particles in the less concentrated increases, the difference in concentration between the two solutions decreases. Hence, the concentration gradient is said to get smaller. All else being equal, the concentrations of the solutions change more rapidly when the difference in their concentrations is greater. This diffusion process continues until the concentrations of the two solutions are equal. This state is known as dynamic equilibrium. When the two solutions are in dynamic equilibrium, particles continue to move between the two solutions, but there is no net flow in any one direction. While in transit through the digestive tract the Aegis Fluidics Microcapsules never reach equilibrium and therefore continue to empty their contents until the contents are exhausted. * See drawing next page Page 8