1. The lipid language of
Mr. GAURAV KUMAR PANDIT
SCHOOL OF LIFE SCIENCE
UNIVERSITY OF HYDERABAD
2. The lipid language of plant-
To understand the cross-kingdom communication
Do plants and fungi communicate via oxylipin language?
How fungi and plants recognize exogenous oxylipins ?
What is the significance of this discussion ?
Lipids play vital roles in numerous physiological processes in
oxygenated polyunsaturated fatty acids (PUFA): oxylipins.
Mammals oxylipins : eicosanoids
Microbial oxylipins : fungal oxylipins are better understood .
Oxylipins such as jasmonates are able to regulate signal cross-
talk with other hormones.
6. How fungi induce plant lipid metabolism to utilize plant oxylipins ?
Model for the use of host ligand mimicry ( coronatine ) to manipulate plant
defense response that benefit the fungus.
8. Hypothetical model of oxylipin-mediated signal
communication between plants and fungi
G-Protein mediated regulation - GPCRs
9. What is the significance of this discussion ?
T know about –
Seed contamination by mycotoxigenic fungi
mycotoxins such as aflatoxin causing significant economic losses and food
Aflatoxin is among the most carcinogenic compound naturally found and
when ingested it has acute toxic, immunosuppressive, mutagenic,
teratogenic and carcinogenic effects, mainly on the liver.
Future Aspect –
Molecular signaling during plant-pathogen interactions must be
understood to create and apply better forms of disease resistance in
Lipoxygenase or LOX, in plants, initiates biosynthesis of most oxylipins
some of which are shown to regulate growth and development, biotic and
abiotic stress defense, sex determination, programmed cell death, and
Fungi have another family of dioxygenases , psi-producing oxygenase
(PPO) that incorporate molecular oxygen into fatty acids to produce Psi
(precocious sexual inducer) factors; they stimulate asexual or sexual