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Only for the use of Medical Professionals
By:
A.S.M. Faruk Hossain
Sr. Product Executive,PMD
+8801717678894
Techno Drugs Ltd.
A Perfect combination offer enhanced Efficacy...
Ceflenic ensures best quality as it’s manufacturing
methods follow WHO approved cGMP guidelines.
*Techno Drugs ensures qualitative raw material of
Cefuroxime Axetil & Clavulanic Acid. The raw materials are
imported from USFDA, UKAS and ISO certified sources. As a
result
Ceflenic confirms highest purity and quality.
MOA:
MOA of Cefuroxime and Clavulanic acid:
Cefuroxime acts by inhibiting bacterial cell wall synthesis. Lack of bacterial cell wall results in
death due to lysis of bacteria.
 Clavulanic acid has a similar structure to the beta-lactam antibiotics but binds irreversibly to the
beta-lactamase enzymes.
 Used in combination with the beta-lactam antibiotics, it has become one of the most prescribed
antibiotics prolonging the effective life of antibiotics. Thus, the combination of cefuroxime and
clavulanic acid (β-lactamase inhibitor) provides a solution for treatment of bacterial infections
caused by beta lactam resistant pathogens.
Product Profile:
 Brand Name: Ceflenic
 Generic Name: Cefuroxime + Clavulanic Acid
 Therapeutic Class: second generation cephalosporin
 Strengths: 250 Tablet.
500 Tablet.
Indication and Usage:
Pharyngitis/Tonsilliti
s
caused by
Streptococcus pyogenes.
Indication and Usage:
Acute Bacterial Maxillary Sinusitis
caused by
Streptococcus pneumoniae or
Haemophilus influenzae
Indication and Usage:
Acute Bacterial Exacerbations
of Chronic Bronchitis by
Streptococcus pneumoniae,
Haemophilus Influenzae
The ideal choice to treat Respiratory Tract Infections
Indication and Usage:
Uncomplicated Skin and Skin-
Structure Infections caused by
Staphylococcus aureus (including β-
lactamase–producing strains)
or Streptococcus pyogenes.
Indication and Usage:
Uncomplicated Urinary Tract
Infections caused by
Escherichia coli or
Klebsiella pneumoniae.
Indication and Usage:
Uncomplicated Gonorrhea,
(urethral and endocervical) caused
by
Neisseria gonorrhoeae.
Indication and Usage:
Early Lyme
disease caused by
Borrelia burgdorferi.
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Use in pregnancy & lactation:
During pregnancy: While all antibiotics should be avoided in
the first trimester if possible.
However, Ceflenic can be safely used in later pregnancy to treat
urinary and other infections.
During lactation: Because Cefuroxime-clav is excreted in
human milk, consideration should be given to discontinuing
nursing temporarily during treatment with Cefuroxime.
US FDA Pregnancy Category ‘B’
Returns back the efficacy of Cefuroxime against resistant
pathogens
In a study, the sensitivity of 40 ß-lactamase producing isolates was recorded. The
study was done by using antibiotic disks of Cefuroxime and the disks containing
same concentration of the Cefuroxime with ß-lactamase inhibitor Clavulanic Acid.
Result:
Sensitivity of ß-lactamase producing strains was increased significantly
using combination of Cefuroxime and Clavulanic Acid.
Ensures desired efficacy of Cefuroxime against resistant
pathogens.
0
20
40
60
80
100
Cefuroxime Cefuroxime +
Clavulanic
Acid
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Unique Selling Points:
1. Highly effective against both beta-lactamase- producing & non
producing Gram (+ve) & Gram (–ve) negative bacteria.
2. Returns back the efficacy of Cefuroxime against resistant pathogens
3. Ensures effective treatment of upper,lower RTIs & Gynecological
infections.
Sl. Brand Name Company Pack Size MRP/Tablet
Monthly Average Sales
Rx Share
Box Value (Lac)
1
Clavusef 250
Opsonin
2 x 6’s 30.00 50000 135.34 29.92
1 x 6’s 50.00 40000 120.30 28.09Clavusef 500
2
Cefaclav 250
Incepta
2 x 6’s 30.00 43000 116.39 10.09
Cefaclav 500 2 x 4’s 50.00 45000 135.34 13.37
3
Cerox CV 250
ACI
2 x 7’s 30.00 37000 100.05 15.46
Cerox CV 500 2 x 4’s 50.00 28000 112.00 14.72
4
Kefuclav 250
SK + F
2 x 7’s 30.00 21000 56.84 8.83
Kefuclav 500 1 x 7’s 50.00 19000 57.14 10.84
5
Furoclav 250
Renata
2 x 6’s 30.00 16000 43.31 9.73
Furoclav 500 2 x 4’s 50.00 19000 57.14 9.85
6
Fuclav 250
Drug Int.
2 x 7’s 30.00 12000 32.48 11.67
Fuclav 500 2 x 7’s 50.00 8000 24.06 11.29
7
Xiclav 250
Ziska
2 x 5’s 30.00 10000 27.07 10.88
Xiclav 500 2 x 4’s 50.00 5000 15.04 8.76
8
Ximeclav 250
Globe
2 x 5’s 30.00 9000 24.34 2.37
Ximeclav 500 1 x 6’s 50.00 7000 21.05 2.35
9
Cefurim CV 250
Somatec
2 x 6’s 30.00 5600 15.16 1.54
Cefurim CV 500 2 x 4’s 50.00 1733 5.21 0.72
Competitive Market Analysis for Tablets:
Major Target Doctors for Tablets
1. Gynecologists
2. Dentists
3. Medicine Specialists
4. ENT Specialists
5. Orthopedics
6. Surgeons
7. Skin & VD Specialists
8. Chest Specialists
9. Urologists
10. GPs
11. RMPs
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)
Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)

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Ceflenic (Cefuroxime + Clavulanic Acid by Techno Drugs Ltd.)

  • 1. Only for the use of Medical Professionals By: A.S.M. Faruk Hossain Sr. Product Executive,PMD +8801717678894 Techno Drugs Ltd.
  • 2. A Perfect combination offer enhanced Efficacy... Ceflenic ensures best quality as it’s manufacturing methods follow WHO approved cGMP guidelines. *Techno Drugs ensures qualitative raw material of Cefuroxime Axetil & Clavulanic Acid. The raw materials are imported from USFDA, UKAS and ISO certified sources. As a result Ceflenic confirms highest purity and quality.
  • 4. MOA of Cefuroxime and Clavulanic acid: Cefuroxime acts by inhibiting bacterial cell wall synthesis. Lack of bacterial cell wall results in death due to lysis of bacteria.  Clavulanic acid has a similar structure to the beta-lactam antibiotics but binds irreversibly to the beta-lactamase enzymes.  Used in combination with the beta-lactam antibiotics, it has become one of the most prescribed antibiotics prolonging the effective life of antibiotics. Thus, the combination of cefuroxime and clavulanic acid (β-lactamase inhibitor) provides a solution for treatment of bacterial infections caused by beta lactam resistant pathogens.
  • 5. Product Profile:  Brand Name: Ceflenic  Generic Name: Cefuroxime + Clavulanic Acid  Therapeutic Class: second generation cephalosporin  Strengths: 250 Tablet. 500 Tablet.
  • 7. Indication and Usage: Acute Bacterial Maxillary Sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • 8. Indication and Usage: Acute Bacterial Exacerbations of Chronic Bronchitis by Streptococcus pneumoniae, Haemophilus Influenzae The ideal choice to treat Respiratory Tract Infections
  • 9. Indication and Usage: Uncomplicated Skin and Skin- Structure Infections caused by Staphylococcus aureus (including β- lactamase–producing strains) or Streptococcus pyogenes.
  • 10. Indication and Usage: Uncomplicated Urinary Tract Infections caused by Escherichia coli or Klebsiella pneumoniae.
  • 11. Indication and Usage: Uncomplicated Gonorrhea, (urethral and endocervical) caused by Neisseria gonorrhoeae.
  • 12. Indication and Usage: Early Lyme disease caused by Borrelia burgdorferi.
  • 15. Use in pregnancy & lactation: During pregnancy: While all antibiotics should be avoided in the first trimester if possible. However, Ceflenic can be safely used in later pregnancy to treat urinary and other infections. During lactation: Because Cefuroxime-clav is excreted in human milk, consideration should be given to discontinuing nursing temporarily during treatment with Cefuroxime. US FDA Pregnancy Category ‘B’
  • 16. Returns back the efficacy of Cefuroxime against resistant pathogens In a study, the sensitivity of 40 ß-lactamase producing isolates was recorded. The study was done by using antibiotic disks of Cefuroxime and the disks containing same concentration of the Cefuroxime with ß-lactamase inhibitor Clavulanic Acid. Result: Sensitivity of ß-lactamase producing strains was increased significantly using combination of Cefuroxime and Clavulanic Acid. Ensures desired efficacy of Cefuroxime against resistant pathogens. 0 20 40 60 80 100 Cefuroxime Cefuroxime + Clavulanic Acid
  • 19. Unique Selling Points: 1. Highly effective against both beta-lactamase- producing & non producing Gram (+ve) & Gram (–ve) negative bacteria. 2. Returns back the efficacy of Cefuroxime against resistant pathogens 3. Ensures effective treatment of upper,lower RTIs & Gynecological infections.
  • 20. Sl. Brand Name Company Pack Size MRP/Tablet Monthly Average Sales Rx Share Box Value (Lac) 1 Clavusef 250 Opsonin 2 x 6’s 30.00 50000 135.34 29.92 1 x 6’s 50.00 40000 120.30 28.09Clavusef 500 2 Cefaclav 250 Incepta 2 x 6’s 30.00 43000 116.39 10.09 Cefaclav 500 2 x 4’s 50.00 45000 135.34 13.37 3 Cerox CV 250 ACI 2 x 7’s 30.00 37000 100.05 15.46 Cerox CV 500 2 x 4’s 50.00 28000 112.00 14.72 4 Kefuclav 250 SK + F 2 x 7’s 30.00 21000 56.84 8.83 Kefuclav 500 1 x 7’s 50.00 19000 57.14 10.84 5 Furoclav 250 Renata 2 x 6’s 30.00 16000 43.31 9.73 Furoclav 500 2 x 4’s 50.00 19000 57.14 9.85 6 Fuclav 250 Drug Int. 2 x 7’s 30.00 12000 32.48 11.67 Fuclav 500 2 x 7’s 50.00 8000 24.06 11.29 7 Xiclav 250 Ziska 2 x 5’s 30.00 10000 27.07 10.88 Xiclav 500 2 x 4’s 50.00 5000 15.04 8.76 8 Ximeclav 250 Globe 2 x 5’s 30.00 9000 24.34 2.37 Ximeclav 500 1 x 6’s 50.00 7000 21.05 2.35 9 Cefurim CV 250 Somatec 2 x 6’s 30.00 5600 15.16 1.54 Cefurim CV 500 2 x 4’s 50.00 1733 5.21 0.72 Competitive Market Analysis for Tablets:
  • 21. Major Target Doctors for Tablets 1. Gynecologists 2. Dentists 3. Medicine Specialists 4. ENT Specialists 5. Orthopedics 6. Surgeons 7. Skin & VD Specialists 8. Chest Specialists 9. Urologists 10. GPs 11. RMPs