1. AUSHADH PRESENTATION
MEDICINE IN PRATSHYAYA
BY DR. EISHAN JAIN
UNDER THE GUIDANCE OF ALL TEACHING
STAFF OF KAUMARBHRITYA DEPARTMENT
1

2. INRODUCTION
• The disorder of nasa have been described widely by all the Acharyas.
Acharya Susrutha has described 31 nasagatha rogas. Among them
pratishyaya is one of the most important disease.
• He has described the disease very elaborately including its
complications as diseases of eyes, nose and ear.
• On the basis of signs and symptoms, the disease pratishyaya can be
compared to allergic rhinitis in modern medicine characterized by
sudden and frequent attacks of sneezing, profuse watery nasal
discharge associated with nasal obstruction which is intermittent
watering of eyes, heaviness of head, respiratory distress and anosmia.
• Allergic reaction is produced when the body comes in contact with
allergens.
2

3. निरुक्ति
सुश्रुि संहििा २४
3

4. निदाि
4

5. पूर्वरूपम्
5

6. संप्राक्ति
6

7. सम्प्राप्ति
• Nidana Sevana
• Vitiation of Vata Dosha
• Sama Kapha, Pitta and Rakta causes Avarana of this Vriddha Vata
• Obstructing its Gati
• Doshas get lodged in Shirah Pradesh
• This Vriddha Vata expels out Kapha, Pitta & Rakta through Nasal route
• Pratishyaya
7

8. Samprapti Ghataka of Pratishyaya
• Dosha - Vata Kapha Pradhana, Alpa Pitta
• Dushya - Rasa, Rakta
• Agni - Jatharagni, Rasadhatwagni
• Ama - Rasadhatwagnimandhya
• Srotas - Pranavaha, Rasavaha
• Srotodushti - Sanga,Vimargagamana, Atipravruthi.
• Udbhavasthana - Amashaya
• Sancharisthana - Gala, Urdhwajatru, Nasa, Ganda Pradesha
• Vyaktasthana - Nasa
• Rogamarga - Abhyantara
• Vyadhiswabhava - Ashukari
• Vyadhi Avastha - Vyakta
• Adhisthana - Nasa, Shiras 8

9. Types of प्रनिश्याय
• According to आचायव सुश्रुि
1. र्ािज प्रनिश्याय
2. पपत्तज प्रनिश्याय
3. कफज प्रनिश्याय
4. संक्निपािज प्रनिश्याय
5. दुष्टज प्रनिश्याय
6. रतिज प्रनिश्याय
9

10. TREATMENT OF PRATISHYAYA
10

11. Sl.
No.
Name of the
formulation
Dosage
form
Daily dose Anupana Reference
1 Shunthi Churna 3gm bd Honey
D.V- vol2
P.V sharma
2. Maricha Churna 3gm bd Curd & jaggery B.R. Nasa roga
3. Citraka haritai Avlehya 12 gm bd Water/ milk B.R. Nasa roga
4. Vyoshadi vati Vati 1 gm bd Chewable S.S.Ma.K
5. Laxmivilasrasa Vati 250 mg bd Honey B.R. rajyashma chi.
6. Anu taila Taila 2 drops S.Y.Pa.P
11

12. HARIDRA
• Phyto-constituents- curcumin 50-60%
• Rasapanchaka
• Rasa –Tikta, Katu PITTA SHAMAK
• Guna- Ruksha, Laghu
• Veerya – Ushna KAPHA SHAMAK
• Vipaka - katu
• Prabhava – krimighna
• Dosha karma – Kapha pittahara.
12

13. • Respiratory System- Its tikta and tikshna property act as a
expectorant.
13

14. Mechansm of Haridra in breaking pathophysio of rhinitis
Foreign particle
Inflammation
Mucous metaplasia
Excess mucous
Rhinitis
14

15. MARICHA
• RASA PANCHAKA
• RASA – Katu
• GUNA – Rooksha, teekshna
• VEERYA – Ushna
• VIPAKA – Katu
• DOSHAGHNATA - KaphaVatahara
15

16. CHEMICAL CONSTITUENTS
• Through its active component Piperine, Black Pepper is able to
modify supplement and drug metabolism.
• Piperine inhibits drug detoxifying enzymes. This typically
increases bioavailability of any compound which would
normally be attacked by said enzymes.
• Kantakari Ghrita – Given to children with complaints of
shwasa, kasa, jwara, aruchi.
(Bhai. Rat. Balaroga)
16

17. VACHADI SYRUP
17
S.N DRUG BOTNICAL NAME
USABLE
PART
1. Vacha Acorus calamus Linn. Rhizome
2, Yavani Trachyspermum ammi Linn. Fruit
3. Aamalaki Phyllanthus emblica Linn. Fruit
4. Vibhitaki Terminalia belliricaRoxb. Fruit
5. Haritaki Terminalia chebula Retz. Fruit
6. Shunti Zingiber officinalis Roscoe. Rhizome

18. 18
DRUGS RASA GUNA VIRYA VIPAKA DOSHKARMA
Vacha Katu-tikta Guru, tikshna Ushna Katu Vatakaphahara
Yavani Katu-tikta Guru, tikshna ushna Katu Vatakaphahara
Aamalaki
Amla pradhan
panchrasa
Guru, ruksha Sheeta Madhur Tridoshahara
Vibhataki Kashaya Laghu, ruksha Ushna Madhur Tridoshahara
Haritaki
Kashaya
pradhan
panchrasa
Laghu, ruksha Ushna Madhur Tridoshahara
Shunti Katu
Guru, ruksha,
tiksna
ushna Madhur Vatakaphahara

19. Mode of action of Vachadi syrup
• The drug for the clinical study was referred from Harita Samhita, 3rd
sthana, 2nd chapter where Acharya Harita has explained the
treatment for Pratishyaya (rhinitis) in children. The drug contains
ingredients Vacha, Yavani, Amalaki, Vibhitaki, Haritaki and
Shunthi. Here, Vacha, Yavani, Haritaki and Shunthi by their
properties of Ushna Veerya (hot potency), Laghu (lightness),
Teekshnaguna (sharp in property) does Amapachana (digestive),
Vatanulomana (proper movement of Vata) and are VataKapha hara.
Whereas Amalaki and Vibhitaki by their Madhura vipaka(post
digestion) acts as Tridoshahara. Altogether, this drug acts on
Tridosha, corrects Agnimandya (digestive fire), relieves Srotodushti
(clears obstruction in the channels) and does Vatanulomana.
19

20. Discussion
Pratishayaya had got simulation with Allergic rhinits which is the
burning problem in the present generation and as there was no successful
management for these conditionsin allied science. Hence present
clinically study was designed.Vachadi Syrup shows highly significant
result in Nasasrava (nasal discharge)(86%), Gandha-ajnana (loss of sense
of smell) (85%), Mukhashosha (dryness of mouth) (82%),Kshavathu
(sneezing) (78.5%), Ghranavarodha (nasal obstruction) (95%),
Shirovedana (headache) (92.5%), Trishana (thirst)(81%), Kasa (cough)
(80%), Aruchi (loss of appetite)(83%), Nasal congestion(87%), Nasal
itching(80%) relief respectively. Significant result was obtained in
Swarasada (altered voice) with 60%, Shirogaurava (heaviness of head)
with 66% and not significant in Nasagra-paka (nasal mucosa
inflammation) with 40% relief respectively.
20

21. Ingredient Of Vyoshadi Vati
• 1. Sunthi (zinzberofficinale),
• 2. Marich (pipernigrum),
• 3. Pippali (piperlongum),
• 4. Amlavetas (Garcina Peunculata),
• 5. Chavya (Chavivaroburghii)
• 6. Talispatra (Abies webbiana),
• 7. chitrak (Plumbago Zeylancia)
• 8. Jiraka (Cuminum Cyminum)
• 9. Guda (Jaggery) (Black).
21

22. Method of preparation of drug
• All the mentioned drugs were taken in equal quantity in powder
form except Guda (Jaggery).
• Guda (Jaggery) was taken 4 times of all mixture powder.
• Guda (Jaggery) & all powder were mixed properly & tablets
were prepared.
22

23. PROBABLE MODE OF ACTION
• In the pathogenesis of pratishyaya, predisposing factor was Kapha
vitiated diet & vihar. Prime factor was Rasadhatwagni mandyta. Most of
drug having Tikta Rasa, Katu Vipaka & Ushana Virya. They also have
function like Kaphasaman & lekhan (depletive). Amapachana & Dhatu-
Shoshan properties of Vyoshadi Vati normalize the function of Agni. The
drugs possess the Tikta Rasa which helps in the clearing the obstruction
in the Strotas (channels). Kapha & rasadhatu both are Prithvi & Jala
Mahabhuta entities. So in the management of pratishyaya, the drug must
be opposite of these two Mahabhut. This achieved by Tikta Rasa as it
has Khara property. Amlarasa & Guda (Jaggery) has potency to reach
at cellular level & restore function of dhatwagni. The extract of ginger
due to its katu rasa and teekshna guna it acts as vata kapha hara, deepana
and bhedana.
23

24. Laxmi Vilas Ras (Nardiya)
• Reference: Bhaishajya Ratnavali, Rasayana Adhikara 55 – 68.
• It is a Ras Aushadhi. Mercury is known as Rasa in Ayurveda and
medicines that are prepared using purified mercury, purified Sulphur,
Bhasma etc. are named as Ras Aushadhi (Mercurial Preparations). Para,
Parad, Rasa or mercury is a heavy metal that remains liquid at room
temperature. It is used in Ayurveda only after proper detoxification as
per classical Ayurvedic texts. Parad is ingredient of numerous medicines
due to its powerful medicinal properties. It balances Vata, Pitta and
Kapha.
• Ras Aushadhi (Parad containing medicine) are fast acting. It nourishes
whole body and has tonic, aphrodisiac, rejuvenative, anti-aging, wound-
healer, and antimicrobial effect. The combination of mercury with other
medicinal ingredients enhances the therapeutic efficacy of medicine due
to Yogvahi property of Parad.
24

25. Ingredients• 10 g fine powder of each of:-
• Abhraka Bhasma - Purified and processed Mica
• Shuddha Parada - purified Mercury
• Shuddha Gandhaka - purified Sulphur
• Karpoora - Camphor - Cinnamomum camphora
• Jatiphala - Nutmeg (fruit) - Myristica fragrans
• Jatikosha - Nutmeg
• Vriddhadaru - Argyrea speciosa
• Dhattura - Datura metel
• Bhanga - Cannabis sativa
• Vidari - Pueraria tuberosa
• Shatavari - Asparagus racemosus root
• Nagabala - Grewia populifolia
• Atibala - Abutilon indicum
• Gokshura - Small caltrops (whole plant) - Tribulus terrestris
• Kuchula - Strychnos nux vomica
• Nagavalli - Piper betel - juice extract - quantity sufficient.
25

26. • Method of Preparation
• Fine powder ingredients are triturated with each liquid for three
days. Then paste is prepared, and tablets are made.
• Dosage - 250 mg.
• It is traditionally administered along with buttermilk, milk and
fruit juices.
26

27. • In preparation of Ras Aushadhi/medicine first Kajjali is made
from purified Parad and Gandhak. As these medicines contain
heavy metals, it is better to take them as prescription drugs.
• Laxmi Vilas Ras, contains detoxified minerals-metals, cannabis
seeds, Datura seeds and therefore it is recommended to take this
medicine in recommended dosage, under medical supervision.
27

28. Benefits of Laxmi Vilas Ras
• It is a broad spectrum medicine.
• It is a Rasayan (Rejuvenative tonic;nourishes all dhatu and builds Ojas).
• It has anti-pyretic, aphrodisiac, expectorant, antiseptic and stomachic activities.
• It cures all types of fever.
• It is an excellent medicine to treat cough, asthma, fever due to cough, chronic
sinusitis etc.
• It is useful in all twenty types of Prameha.
• It has aphrodisiac property and increases libido.
• It gives strength to heart.
• It cures various diseases of head, skin, and genito-urinary system.
• It improves hemoglobin level, gives strength and nutrition.
28

29. Uses of Laxmi Vilas Ras (Nardiya)
1. Udara
2. Prameha (Urinary disorders)
3. Dhatu Kshaya (Tissue wasting)
4. Urdhvanga Roga.
5. Guda Roga (Anorectal disease)
6. Bhagandara (Fissure)
7. Nadivrana (Fistula)
8. Kushtha (Diseases of skin)
9. Vrana (Ulcer)
10. All kinds of shlipada (Filariasis)
11. Gala-shosha (Dryness in throat)
12. Kasa (Cough)
13. Yakshma (Tuberculosis)
14. Pinasa (Chronic rhinitis/sinusitis)
15. Antra Vriddhi (Hernia)
16. Atisar (Diarrhoea)
17. Amavata (Rheumatism)
18. Disorders of Mouth Ear Nose and Eyes
19. Arsha (Haemorrhoids)
20. Sthaulya (Obesity)
29

30. STUDY ON N.L.V.RAS
• In one trial, 240 cases of bronchial asthma were administered
Nardiya Lakshmi Vilas rasa and Godanti Bhasma in a dose of 0.5
and 1.0 g, respectively, three times/day with honey for a varying
period of 4 to 12 weeks.
• 96 patients received 100% relief.
• 27 patients received 75% relief.
• 50 patients received 50% relief.
• 18 cases received 25% relief.
• and 28 remained unchanged.
• 21 cases left against medical advice.
30

31. VYAGHRI TAILA
• The contents of vyaghri taila are vyaghri, danti, vacha,
shigru, surasa, pippali, maricha, shunti, Saindhava and tila
taila.
31

32. Properties
• Vyaghri has the properties like Antiinflammatory, antibiotic,
vasoconstrictor and histamine releasing activity. Hence it is
proved to be effective in the management of Dushta Pratishyaya
(Chronic Simple Rhinitis).
• Danti is said to be possessing qualities like kaphapittahara
which can be considered as vyadhi pratyanika dravya.
• Further Vacha, shigru, Surasa medicines are also possessing
properties of antibacterial, anti-inflammatory & shirovirechana.
These drugs are immunomodulators also.
32

33. • Pippali has antiallergic activity. A common use of the fruit is
in the prevention of recurrent attacks of bronchial asthma and
common cold.
• Maricha has anti-oxidant, anti- Inflammatory, antibacterial
properties.
• Shunthi inhibits prostaglandin synthesis, antiinflammatory,
antioxidant and antibacterial.
• Tila has properties like free radical scavenging, decreases
susceptibility to oxidative stress. All these factors made Vyaghri
taila, a good ayurvedic medicine for controlling Dushta
Pratishyaya.
33

34. Mode of action of Nasya
• In Purva Karma of Nasya, Abhyanga and Swedana is done. Abhyanga causes Mruduta
of Doshas and Swedana causes Vilayana (liquification) of accumulated Doshas. In the
language of modern science, Abhyanga and Swedana increases the local blood supply
and Swedana also liquefies the mucous. Due to vasodilatation the permeability of
blood vessels increases, which makes the drug absorption faster.
• In Pradhana Karma, the drug in Churna form is administered into the nostrils through
Pradhamana Nadiyantra in the head-low position of the patient. Thus, the drugs reach
the Shringataka and from there, through different Siras, it spreads to other parts like
Netra, Shirah, etc. and removes the morbid Doshas. By the properties of drug, it
causes Srotoshuddhi and makes the Anulomana Gati of Vayu (mitigation of Vayu),
which is hampered in Dushta Pratishyaya.
• In Pashchata Karma, Urdhvanga massage and Swedana helps to drain out the Doshas
and Swedana also causes Srotomukhavishodhana.
• In addition, the drug compound has Srotoshodhana, anti-inflammatory, antibacterial,
etc., properties, which help to treat the disease.
34

35. Pratishyaya Pathya (Do’s) Apathya (Don’ts)
Cereals Old shali rice
Pulses Kulattha, green gram (mudga)
Fruits & vegetables Paravala, drum stick (shigru), radish, garlic
Others
Hot freshly prepared food, jaggery, powder of
roasted cereals (sattu), haritaki, shadangayusha,
shadabindu taila, chyavanaprasha
Life style
Lightening, drinking of clarified butter (ghrita),
sudation, therapeutic emesis (vamana),
snuffing (avapidana nasya)
Use of excessive cold water for
drinking and bathing, excessive worry
(atyadhika chinta), intake of alcohol,
dry food, suppression of natural urges,
day sleeping, sleeping on the ground
35

36. Dushta pratishyaya Pathya (Do’s) Apathya (Don’ts)
Cereals Old shali rice
Pulses Kulattha, green gram (mudga)
Fruits & vegetables Paravala, drum stick (shigru), radish, garlic
Others
Chitraka haritaki, jaggery, curd, black
pepper
Intake of alcohol, dry food
Life style
Intake of warm water, therapeutic emesis
(vamana), shadabindu taila, intake of luke
warm water through nasal passage, smoking
Use of cold water for drinking and
bathing, excessive thinking, suppression
of natural urges, smoke, dust, day
sleeping, sleeping on the ground
36

37. Thank you…
37