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The Truth About
Inflammatory Breast Cancer
      Five Myths Debunked
What Is Inflammatory Breast Cancer?
  • Inflammatory breast cancer, or IBC, is a rare but
    aggressive form of breast cancer.
  • Cancer cells block the lymph vessels of the skin of the
    breast, causing the breast to appear red or inflamed.
  • IBC has a rapid onset of symptoms – pain or itchiness,
    redness, swelling, or thickening of the skin.
  • Inflammatory breast can often occur over weeks or a
    few months. Cancer is often identified by a breast that
    feels thick or heavy, and becomes red, swollen, and
    warm.
As with many forms of cancer, IBC is often
misunderstood.



  Here are five of the most
  common myths about IBC
Myth 1: If there’s no lump, there’s no
         cancer
Unlike other types of breast cancer, IBC may be present
without a lump.

Symptoms can include:
   – Pain or itchiness of the breast
   – Redness of the breast
   – Swelling or enlargement of the breast
   – Swelling of the lymph nodes in the
     armpit or above/below the collarbone
   – Thickening of the skin of the breast or
     ridged or dimpled skin texture
Myth 2: IBC is often properly diagnosed
        at its onset

  • IBC symptoms are often misdiagnosed as an infection
    known as mastitis.
  • Mastitis is treated with antibiotics.
  • If symptoms don’t improve after a few days on
    antibiotics, you should talk to a breast surgeon about
    undergoing breast imaging (mammogram, ultrasound,
    MRI) and a breast biopsy.
  • For more information about IBC, or what to do next,
    call the IBC Program at Dana-Farber/Brigham and
    Women’s Cancer Center: 617-632-4024.
Myth 3:         There are no effective treatments
                for IBC

• There are successful treatments for
  IBC. It is important to identify the
  symptoms that could be IBC so that
  treatment can start quickly.
• Initial treatment includes
  chemotherapy, followed by surgery.
• Because IBC involves the entire
  breast, patients undergo
  chemotherapy and a mastectomy.
• Radiation treatment is used after
  surgery to take care of any residual
  cancer that may be in the chest wall
  or in the lymph nodes.
Myth 4:      If I have a mastectomy as part of
             my treatment for IBC, I can’t
             have breast reconstruction

  • Women who have had IBC can still have breast
    reconstruction.
  • Delaying reconstruction provides the best chance for
    the radiation to eradicate any residual IBC in the skin
    and lymph nodes.
  • We recommend patients wait six to 12 months before
    reconstruction to ensure the body heals properly and
    the reconstruction is successful.
Myth 5:           Because IBC is rare, there is not a
                      lot of focus on research


Dana-Farber is working hard to understand IBC
  and improve treatment:

    • Basic scientists are investigating
      molecular pathways that stimulate the
      growth of IBC.
    • Clinical trials are designed for newly
      diagnosed patients with IBC and
      patients with advanced disease.
    • Clinical trials specifically target IBC
      and some of the important molecular
      pathways that stimulates the cancer’s
      growth.
What Should You Do If You Think You
            Have IBC?
 1.   Don’t ignore your symptoms. See your medical provider
      immediately – early intervention is key for effective
      treatment.
 2.   Your provider may give you antibiotics to treat an
      infection. If your symptoms do not subside within a few
      days, see your provider again to determine whether or
      not your symptoms are characteristic of IBC.
 3.   Once you are diagnosed, see a medical oncologist
      specializing in IBC as soon as possible to begin
      treatment.
 4.   If you think you have IBC, or have been diagnosed, call
      the IBC Program at DF/BWCC for more information or to
      make an appointment: 617-632-4024.
Check out our video discussion with
Dr. Beth Overmoyer, director of the IBC
Program at Dana-Farber/Brigham and
Women’s Cancer Center:
http://www.youtube.com/watch?v=AY6me3iSC8c




For more information on IBC, visit:
http://www.dana-farber.org/Adult-Care/Treatment-and-
Support/Treatment-Centers-and-Clinical-Services/Breast-Cancer-
Treatment-Center/Inflammatory-Breast-Cancer-Program.aspx

Or call 617-632-4024

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The Truth About Inflammatory Breast Cancer

  • 1. The Truth About Inflammatory Breast Cancer Five Myths Debunked
  • 2. What Is Inflammatory Breast Cancer? • Inflammatory breast cancer, or IBC, is a rare but aggressive form of breast cancer. • Cancer cells block the lymph vessels of the skin of the breast, causing the breast to appear red or inflamed. • IBC has a rapid onset of symptoms – pain or itchiness, redness, swelling, or thickening of the skin. • Inflammatory breast can often occur over weeks or a few months. Cancer is often identified by a breast that feels thick or heavy, and becomes red, swollen, and warm.
  • 3. As with many forms of cancer, IBC is often misunderstood. Here are five of the most common myths about IBC
  • 4. Myth 1: If there’s no lump, there’s no cancer Unlike other types of breast cancer, IBC may be present without a lump. Symptoms can include: – Pain or itchiness of the breast – Redness of the breast – Swelling or enlargement of the breast – Swelling of the lymph nodes in the armpit or above/below the collarbone – Thickening of the skin of the breast or ridged or dimpled skin texture
  • 5. Myth 2: IBC is often properly diagnosed at its onset • IBC symptoms are often misdiagnosed as an infection known as mastitis. • Mastitis is treated with antibiotics. • If symptoms don’t improve after a few days on antibiotics, you should talk to a breast surgeon about undergoing breast imaging (mammogram, ultrasound, MRI) and a breast biopsy. • For more information about IBC, or what to do next, call the IBC Program at Dana-Farber/Brigham and Women’s Cancer Center: 617-632-4024.
  • 6. Myth 3: There are no effective treatments for IBC • There are successful treatments for IBC. It is important to identify the symptoms that could be IBC so that treatment can start quickly. • Initial treatment includes chemotherapy, followed by surgery. • Because IBC involves the entire breast, patients undergo chemotherapy and a mastectomy. • Radiation treatment is used after surgery to take care of any residual cancer that may be in the chest wall or in the lymph nodes.
  • 7. Myth 4: If I have a mastectomy as part of my treatment for IBC, I can’t have breast reconstruction • Women who have had IBC can still have breast reconstruction. • Delaying reconstruction provides the best chance for the radiation to eradicate any residual IBC in the skin and lymph nodes. • We recommend patients wait six to 12 months before reconstruction to ensure the body heals properly and the reconstruction is successful.
  • 8. Myth 5: Because IBC is rare, there is not a lot of focus on research Dana-Farber is working hard to understand IBC and improve treatment: • Basic scientists are investigating molecular pathways that stimulate the growth of IBC. • Clinical trials are designed for newly diagnosed patients with IBC and patients with advanced disease. • Clinical trials specifically target IBC and some of the important molecular pathways that stimulates the cancer’s growth.
  • 9. What Should You Do If You Think You Have IBC? 1. Don’t ignore your symptoms. See your medical provider immediately – early intervention is key for effective treatment. 2. Your provider may give you antibiotics to treat an infection. If your symptoms do not subside within a few days, see your provider again to determine whether or not your symptoms are characteristic of IBC. 3. Once you are diagnosed, see a medical oncologist specializing in IBC as soon as possible to begin treatment. 4. If you think you have IBC, or have been diagnosed, call the IBC Program at DF/BWCC for more information or to make an appointment: 617-632-4024.
  • 10. Check out our video discussion with Dr. Beth Overmoyer, director of the IBC Program at Dana-Farber/Brigham and Women’s Cancer Center: http://www.youtube.com/watch?v=AY6me3iSC8c For more information on IBC, visit: http://www.dana-farber.org/Adult-Care/Treatment-and- Support/Treatment-Centers-and-Clinical-Services/Breast-Cancer- Treatment-Center/Inflammatory-Breast-Cancer-Program.aspx Or call 617-632-4024