This document summarizes discussions from a Health Tech Meetup event in Belgrade, Serbia on February 22, 2018. It includes summaries of presentations from several speakers on topics including using wearable devices and the data they provide to impact health insurance premiums, a digital health platform called Mediately that provides drug and pricing information to healthcare professionals, and how technologies like artificial intelligence and machine learning can help with early sepsis detection, accelerating drug development, and improving medical diagnostics and treatment.

2. Teme:
• Sava Marinkovich - Scanz/SkinZ
• Andrija Janidijevid - Wearables i zdravsteno
osiguranje
• Bojan Davinid - Mediately
• Andrej Kravčuk - CUBE Team

3. FB - Health Tech
Meetup – Health Tech
Serbia

6. Gender Issue

7. Obavezna
lektira

8. Bertalan Mesko

9. Bertalan Mesko
The Medical
Futurist

10. Bertalan Mesko

12. MEKATON
U APRILU

13. 28.-29. APRIL 2018.

15. Health Tech Meetup #3
22.03.2018. u 18h
ICT Hub

16. Sava Marinkovich
Health Tech Meetup
February 2018

17. Health + tech + Serbia

21. • Acne care pathway is broken. Patients take
up to 2 years before getting proper care and
resolution in UK and Germany.
• Poor advice. 9/10 Pharmacists in the UK give
incorrect guidance on what Over-the-counter
product to use
• No Standard. 25 Different Severity Scales
globally used by dermatologists.
Acne Affects 600m globally but costly
and painful to patients, practitioners,
and hospitaL

22. • ScanZ helps dermatologists and other practitioners simply and
quickly assess and treat acne.
• Interactive progress tracking motivates patients to find and
stick to the right treatment.
• ScanZ creates large scale data sets to help pharmaceuticals
develop new treatments and therapies for acne and other skin
disease sufferers, as well as to understand patient behaviors
better.
ScanZ is a clinically
validated, easy-to-use
handheld device and e-
health platform that
quantifies acne.

23. Scanz objectively digitizes a patient’s
lesions and features in addition to
quality of life factors
Today ScanZ

24. SCAnz solves acne earlier by
moving point of care closer to the
community and patient

25. partnerships with top hospitals to
clinical validate and publish
papers/healthcare economics, EUR
1.6M Grant
 Berlin,
Germany
 Largest
university
hospital in
Germany/Euro
pe
 Technology
leader
Harrogate, UK
Largest acne practice
in NHS
Standards setter
National Support
(NHS/NIHR)
Double Winner of EU
Horizon 2020 SME
Instrument, Phase I and II
(€1.6M). 3% of applications
granted
Includes regulatory, White
papers, Healthcare
economics
Focus on commercialization
24 month grant (Currently
at M13)
Partners include
Spitzberg Partners LLC

26. First of its kind data base enables
machine learning/AI to drastically
improve standard clinical outcomes.
• S-3 Dermatologist’s
Guidelines for Treatment of
Acne (2016):
Consensus based and
extracted from limited
clinical trials and subjective
ScanZ gives structured
information based on
continuous data sets
to give advanced
analysis

27. SCanZ is integrated within NHS’s
architecture to create next gen
digital integration
• ScanZ worked with NIHR
Digital Acceleration team
to create first end-to-end
Digital Clinical platform
including e-consent
• Anonymized data lake
allows researchers to pull
new insights for papers and
future studies
• Makes future studies easier
to launch and scale
• GDPR Compliance

28. Next steps…
Problem + Team + Tech (Tools) + Environemnt
(Structure)
(ScanZ is also looking for a marketer to join ;-) )

29. wearables x health insurance
2/22/18
Andrija Janidijevid

30. Wearable technology, wearables, fashionable
technology, wearable devices, tech togs, or fashion
electronics are smart electronic devices (electronic device
with micro-controllers) that can be worn on the body as
implants or accessories….
Wearable devices such as activity trackers are a good
example of the Internet of Things, since "things" such as
electronics, software, sensors, and connectivity are
effectors that enable objects to exchange data (including
data quality) through the internet with a manufacturer,
operator, and/or other connected devices, without
requiring human intervention.
Apart from commercial uses, wearable technology is
being incorporated into navigation systems, advanced
textiles, and healthcare.
definition
2/22/18 Andrija Janicijevic

31. 2/22/18 Andrija Janicijevic
sport and fitness

32. 2/22/18 Andrija Janicijevic
eurosport

33. 2/22/18 Andrija Janicijevic
definition

34. 2/22/18 Andrija Janicijevic
beginning of the circles

35. 2/22/18 Andrija Janicijevic
carrots

36. 2/22/18 Andrija Janicijevic
results

37. Industry
Medicine
Employers
Businesses
2/22/18 Andrija Janicijevic
the doctor is you

38. Many large companies and organizations are beginning to encourage the
use of wearables. Some corporations offer incentives for those who use
wearables and track their fitness. The latest craze is using information
from your wearable to reduce health insurance premiums.
change is already here
2/22/18 Andrija Janicijevic

39. Switzerland
2/22/18 Andrija Janicijevic

40. •Patients with metabolic syndrome
•Pre-diabetes
•Type-2 diabetes
Germany
2/22/18 Andrija Janicijevic

41. United States
2/22/18 Andrija Janicijevic

42. Srbija
2/22/18 Andrija Janicijevic

43. Affordable Care Act presently bars insurance companies from
denying coverage to patients with preexisting conditions.
2/22/18 Andrija Janicijevic
the Dark side

44. Health Tech #2
mag. farm. Bojan Davinid / Mediately

45. Šta nas čeka u bududnosti zdravstva?

48. Današnji plan
Evolucija tehnologije
Medicinske informacije na dlanu
Veštačka inteligencija
Razvoj novih lekova

49. Beba!
Tehnologij
a je
rođena.Tehnologija ima
jako malo uticaja
i upotrebe. Još
uvek smo
radoznali.
1960-te
Malo
veda
beba!
Tehnologija je na
univerzitetima i u
institucijama.
Počinjemo da
obradamo pažnju.
1970-
te
Dete!
Igramo se i
učimo.
Tehnologija ulazi
u domove i
počinje da utiče
na naše
ponašanje.
1980-
te
Tinejdžeri!
Hodemo, a
ne znamo
šta.Tehnologija je
svuda oko nas,
mnogo je
napredovala, i
povezujemo se
globalno.
1990-
te
Odrastamo
, i skroz je
kul.
Instant globalna
komunikacija.
Tehnologija je
eksplodirala.
2000-
te
Dobrodošl
i među
odrasle!
Tehnologija je
upletena u naš
ceo život. Ne
”koristimo” je
ved je sada deo
nas.
2010-
te

50. Broj korisnika interneta globalno (u milijardama)

51. 1,453 leka je odobreno od FDA do kraja 2013.

52. Koji je prvi FDA
odobreni lek?
1827
Merck - Mofin
1899
Aspirin

53. Današnji plan
Evolucija tehnologije
Medicinske informacije na dlanu
Veštačka inteligencija
Razvoj novih lekova

54. Vodeća zdravstvena IT kompanija u regionu

55. “Mediately Baza Lekova”
Informacije o lekovima i
cenama lekova
Alati za pomod u radu
Klasifikacija bolesti
110.000
registrovanih korisnika
40,000
lekara
7
država

56. Baza Lekova u Srbiji
6,659 lekova
30,000
registrovanih korisnika
11,500
lekara
4,000
farmaceuta

59. Lekari i farmaceuti i ostali zdr. radnici
u Srbiji mesecno koriste Bazu Lekova
350.000x
Svakog minuta 8 zdravstvenih radnika
koristi Bazu Lekova

60. Mediately RESEARCH
Anketirali smo
1,152 lekara
O prijavama neželjenih reakcija
na lek

61. Koliko lekara nikada nije prijavilo NRL?

62. Zašto NE?

63. Da li se ovaj problem može rešiti?

64. Pod kojim uslovima bi više prijavljivali NRL?

65. Koliko treba da traje proces prijave NRL?

67. Ako u svakom traženju leka uštedimo
1 sekund
= zdravstveni sistem je uštedeo =
350,000 sekundi
5,800 minuta
97 sati
4 dana

68. Današnji plan
Evolucija tehnologije
Medicinske informacije na dlanu
Veštaĉka inteligencija
Razvoj novih lekova

69. Upala grlaDan 1
Simptomi upale plućaDan 3
Septiĉki šok, telo u kriziDan 7
TahikardijaDan 6
Intenzivna negaDan 8
Otkazuju bubrezi,
pluća...
Dan 14
SmrtDan 22
Primer:
Gospođa Mani je došla
u ER sa upalom grla.
Ostala je 22 dana.
Mani je primila ispravne
lekove i tretman, ali
prekasno.
Ono što joj se desilo je
sepsa.

70. Sepsa može da se spreči ako se detektuje rano!
Lekarima je jako teško da je rano otkriju.
Možemo da koristimo velike količine podataka i
machine learning da rešimo ovaj problem.
Promena u zdravstvu je uvođenje digitalnih kartona. Svi vaši podaci se
uzimaju i program analizira i poredi podatke među hiljadama pacijenata.
Ali softer mora da proceni šta znači koji signal u kontekstu ostalih signala.
Dr Suchi Saria
https://suchisaria.jhu.edu

71. 4-7%
POVEĆAN RIZIK
OD SMRTI
1 SAT
ODLAGANJA
TRETMANA

72. 24 SATA
PRE ŠOKA ORGANIZMA
2/3 VIŠE PACIJENATA
PRE OTKAZIVANJA ORGANA
60% POVEĆANJE
UĈINKA OTKRIVANJA
*16,000 pacijenata

73. 1. Do godine 2035 AI de biti na istom nivou
kao ljudi
Do godine 2045 AI de biti inteligentnija od
svih ljudi zajedno

74. 1500 godina
potrebno da se duplira znanje pre n.e.
250 godina
Kad smo počeli da pišemo knjige
25 godina
Razvoj nauke i nova otkrida
8 godina
Rast internet tehnologija
1 godina
“information age”

75. Mozak više ne može da prati sve ovo,
tako da nam treba pomod AI.
Mozak ima
85.000.000.000
neurona

76. 1%

77. AI + Machine learning

78. Današnji plan
Evolucija tehnologije
Medicinske informacije na dlanu
Veštačka inteligencija
Razvoj novih lekova

79. Od molekula do leka
10-12 godina
2,000,000,000 €

80. Od molekula do leka
PREDKLINIČKE
STUDIJE
<250 supstanci
3 GOD
3 GOD
TESTIRANJE
MOLEKULA
10,000 supstanci
2 GOD
KLINIČKA
ISPITIVANJA
5 supstanci, 3
faze
2 GOD
ODOBRENJE
FDA, EMA
2 GOD
FAZA 4
Pradenje i
farmakovigelanc
a

81. AI (BIG DATA, Machine learning) može da se koristi u
razvoju novih lekova*
Cilj je da se deo procesa smanji sa 5 godina na jednu!
5
godina
* $43 million GSK-Exscientia deal shows AI advancing
1
godina

82. Od molekula do leka – korak napred
PREDKLINIČKE
STUDIJE
<250 supstanci
3 GOD
3 GOD
TESTIRANJE
MOLEKULA
10,000 supstanci
2 GOD
KLINIČKA
ISPITIVANJA
5 supstanci, 3
faze
2 GOD
ODOBRENJE
FDA, EMA
2 GOD
FAZA 4
Pradenje i
farmakovigelanc
a
AI + Machine Learning

83. Današnji plan
Evolucija tehnologije
Medicinske informacije na dlanu
Veštačka inteligencija
Razvoj novih lekova

84. Digitalizacija sveta i zdravstva, kao i veštačka
inteligencija doprinose puno!
Pronalazak novih lekova
Rana i preciznija dijagnostika
Kvalitetnije lečenje

85. Hvala na pažnji

86. Health Tech Meetup #2
Beograd, 22. II 2018.Andrej Kravčuk

87. Istorija

88. 20. vek- transformacija
ENI
AC

92. Bududnost

94. Andrej Kravčuk
+381 64 11 08 641
a.kravcuk@cubeteam.com
andrejkravcuk@gmail.com

95. Hvala na pažnji
i
podršci