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Part E.
LEVEL 6 Clinical Medical Research Building, The Royal Melbourne Hospital
Post: PO Box 2135, RMH, Victoria, 3050
P: +61383445673
M: +61408467548
F: +61386794445
E: colin.royse@unimelb.edu.au
September
14
Curriculum Vitae
Colin Royse, MBBS, MD, FANZCA
Professor
The University of Melbourne
Department of Surgery
Consultant Anaesthetist
The Royal Melbourne Hospital
CV Colin Royse
2
Personal Details
DOB: 7 May 1964
Married to Carolyn Royse, 2 children, Cameron and Georgia
Tel: 0408467548
e-mail: colin.royse@unimelb.edu.au
Qualifications
2000 Doctorate of Medicine (by thesis), The University of Melbourne: “Applications of
echocardiography in cardiac surgery and anaesthesia”
1996 Fellow of the Australian and New Zealand College of Anaesthetists
1987 Bachelor of Medicine, Bachelor of Surgery, The University of Melbourne
1981 Higher School Certificate, Melbourne High School
Academic Appointments
2010- Promoted to Level E, full time continuing. Co-Director of the Ultrasound
Education Unit, Department of Surgery
2006-2010 Level D Full-time continuing appointment,
Head, Anaesthesia and Pain Management Unit, Department of
Pharmacology
2004-2006 Level D @0.5FTE, Department of Pharmacology
Executive, Cardiovascular Therapeutics Unit
2002 Principal Fellow, Department of Pharmacology
2000 Senior Fellow, Department of Pharmacology, The University of
Melbourne.
Head Human Cardiovascular Research Laboratory.
1996-1999 Doctorate of Medicine student
Clinical appointments
1996 - Consultant Anaesthetist
The Royal Melbourne Hospital, 1996-
P.A.N.C.H. 1996
St. Vincent’s Hospital, 1996-7
1991-1996 Anaesthesia Registrar
The Royal Melbourne Hospital
Albury Base Hospital
The Royal Women’s Hospital
The Royal Children’s Hospital
1988 -1991 Hospital Medical Officer
Austin Hospital, Bendigo Base Hospital and The Royal Melbourne
Hospital
CV Colin Royse
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Research appointments
2012 Director, Anaesthesia and Pain Management Unit, Department of Surgery, and
Co-director, Ultrasound Education Group.
2006 Director, Anaesthesia and Pain Management Unit, Department of Pharmacology
Commenced animal based research in addition to clinical research.
2005 Executive, Cardiovascular Therapeutics Unit, Department of Pharmacology
2000 Laboratory head, Human Cardiovascular Research Laboratory, Department of
Pharmacology.
Research
In 1995, I was one of the first Australian anaesthetists to learn and perform transoesophageal
echocardiography for cardiac anaesthesia. I followed this clinical pioneering practice with
research designed to validate its use and to investigate new areas for which it could be useful.
The applications of echocardiography and surface ultrasound use have increased since then
and I have pioneered the use of these technologies in non-cardiac anaesthesia, nerve blocks
and vascular access. Research projects have mirrored these innovations.
I have also been involved in research for surgical innovations and these often overlap with
innovations in anaesthesia. My interests in ventricular function led me to want to validate
new echocardiography measurement techniques against the gold-standard invasive
techniques that are mostly only performed in animal preparations. This was the impetus to
set up an animal laboratory at The University of Melbourne and to invest in pressure-volume
loop equipment (my lab is one of the few in the country with this technology). What followed
was a growing interest in anaesthetic pharmacology and the area of organ protection. This
has led back to human clinical research where I carried out a randomized trial of anaesthetic
agents, looking at brain protection. I am now involved in a number of multicentre clinical
trials of outcome in cardiac surgery.
What started as pure clinical research has therefore moved to the laboratory and now again to
human research, and is a good example of “bench-bedside” translational research. In this
journey, I have supervised many students (see below) and engaged anaesthetists in research
higher degree training. I now supervise or co-supervise more anaesthetists doing higher
degree research than any other anaesthetist in Australia.
Productivity in relation to opportunity
My career citations are > 2000, and I have published >130 peer- reviewed papers and book
chapters, with more than 25% in the leading journals of the discipline. One hundred and
thirteen are in indexed journals, and I currently publish 8-10 papers per year with half as
first or senior author. Most of my research time in the past was “honorary”, and completed
while I was working full time in clinical practice. It is only since late 2006 that I have been full
time teaching and research. In 2005 I had six months absence whilst receiving treatment for a
serious illness, and it took a further six months to return to full research capacity. I also spent
most of my time in 2003 and 2004 developing the Postgraduate Diploma of Perioperative and
Critical Care Echocardiography. This was such an enormous task, that I had to reduce my
research commitment. I believe that my productivity has been outstanding, and more
remarkable given the limited opportunity.
CV Colin Royse
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Interests
a. Cardiovascular and neurological effects of anaesthesia in animals. There is a range of
research preparations in the Cardiovascular Therapeutics Unit, including organ bath and
myograph in-vitro preparations, anaesthetized animal preparations, and pressure-volume
loop preparations in rats, rabbits and pigs. This last technology, which is only available in a
few labs in Australia and world wide, allows direct measurement of contractility. These
preparations are supplemented by histology and molecular techniques provided by
collaborators. These techniques have been used to investigate the cardiovascular effects of
anaesthetics, novel inotropes, cardioprotection and safety pharmacology especially with local
anaesthetics. A new area of research is studying the neurotoxicity of anaesthetics in rats using
cognitive function testing. This important development will complement human clinical
research in this area. I received an ANZCA academic enhancement grant for 2012 to further
develop this research and to build capacity in basic science research for Anaesthesia. I have
closed my lab in Pharmacology due to a move to Department of Surgery, but I am still engaged
with collaborators.
b. Echocardiography
Validation of echocardiography measurements is being carried out in animals and humans. ,
Animal and human volunteer studies are investigating the accuracy of Tissue Doppler Velocity
measurements of systolic and diastolic function. These approaches hold great promise as the
measurements are simple to perform and non-invasive The new horizon in echocardiography
is 3-dimensional real time echocardiography, and several studies validating its use have
commenced. At the lower end of technology, the use of limited transthoracic
echocardiography as a real time clinical diagnostic and monitoring tool is being investigated
in the preoperative assessment clinic, and in the emergency department. These studies focus
on how the echocardiography scan influences clinical management decisions. I am currently
investigating the validity of echocardiography assessment of left and right atrial pressure in
awake and anaesthetized patients using transthoracic and transoesophageal
echocardiography. I am also conducting research into echocardiography education, especially
with simulation technologies.
c. Human organ protection during cardiac surgery
I was the principal investigator in a trial comparing the effects of two anaesthetic agents on
the incidence of postoperative cognitive dysfunction (POCD) after cardiac surgery. This
human study mirrored the animal investigations on the balance between potential
neurotoxicity caused by anaesthetics versus the potential neuroprotective effects during a
period of potential organ injury, such as occurs during cardiac surgery. I am an investigator in
a multicentre trial investigating the effect of high-dose steroids in cardiac surgery, and in
blood transfusion strategies.
d. Recovery after anaesthesia and surgery: Postoperative Quality of Recovery Scale
(PQRS)
I am the only Australian anaesthetist , and now Chair of an international board that developed
and and validated a new scale, the Postoperative Quality of Recovery Scale (PQRS) to
measure how well patients recover after anaesthesia. The first study, was published in
Anesthesiology (2010), the most prestigious anaesthetic journal. This scale has been used as
a research tool to compare different anaesthetic interventions, but is also being developed as
a clinical quality tool. Being able to measure recovery will give anaesthetists important
feedback on their practice, as well as being able to identify patients early after surgery who
have not recovered well.. This work has great potential to engage The University of
CV Colin Royse
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Melbourne hospitals in collaborative research. PQRS is a simple tool to use and can be
performed with minimal training. Quality of recovery is a new horizon in anaesthesia
research and will interest the wider community. This is particularly important when engaging
some of the hospitals where research is poorly developed.
e. Cardiac surgery I am a co-investigator in cardiac surgery research. This includes long-term
follow-up of patients who have had total arterial coronary bypass surgery, as well as
measuring the effect of surgery on diastolic function.
Teaching
I am involved in both undergraduate and postgraduate education. I am also involved in
registrar training in anaesthesia and pain management at The Royal Melbourne Hospital.
Undergraduate:
BBiomed, Medical and Dental students on anaesthesia-related subjects as required. I
supervise students the MD scholarly selective and vocational selective programs.
AMS/Honors
I have supervised AMS students from the inception of the program. I have supervised 3
Science Honours students. Most students have achieved H2A/H1.
Registrar training
I train registrars in anaesthesia through my public hospital sessions.
Research for higher degrees
The table below shows the research students that have been/are under my supervision. All
these students are anesthetists or critical care specialists. I believe that I am the only Victorian
anaesthetist supervising PhD students who are clinicians
Type: AMS = Advanced Medical Science; Hon = Science Honors; Mast = Masters, PhD =
Doctorate of Philosophy; MD = Doctorate of Medicine; DPsych = Doctorate of Psychology.
Supervisor: P = Primary supervisor; Co = Co-supervisor CoE = Co-supervisor for institution
other than The University of Melbourne
Year Name Type Supervisor Mark
2014 Jared Ou-Young Hon P In Progress
2014 Andrea Bowyer PhD P In Progress
2013 Alwyn Chuan PhD Co (McQuarie) In Progress
2012 Kavi Haji PhD P In progress
2011 John Faris PhD Co (UWA) In progress
2010 David Canty PhD Co (Utas) Completed
2009 Mohamed Ali MD Co (Uni Minah,
Egypt)
Withdrawn
2009 Darsim Harji PhD P Completed
2009 Emma Bourne Hon Co H2A
2007- Alicia Dennis PhD P Completd
2007 Andrew Huhn AMS P H2A
2006- Edward Hinch Mast Co Withdrawn
2006- David Andrews PhD P Completed
2006 Greg Chang AMS P H2A
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2005- Graeme McLaren MD P On leave
2005- Paul Soeding PhD P Completed
2005- Kenneth Tung AMS P H1
2005- David Liew AMS P H2A
2005- Amanda Reid Mast Co H2A
2004 Jue Li Seah AMS P H2A
2003 Samuel Sha AMS P H1
2003- Kim Connelley PhD Co Completed
2002 Cheryl Remedios DPsych CoE Completed
2002 David Deelen AMS P H2A
2002 Ajay Bhratula AMS P H1
2002 Maal Roganathan AMS P H2B
2001 Christina Wong AMS P H1
2001 Randal Rohrlach Hon P P
Distance based Echocardiography courses:
The echocardiography education group, which I lead, is the main provider of
echocardiography education to anaesthesia and critical care specialistsin Australia, and has
gained a strong national and international reputation. The education program has facilitated
the uptake of this technology into clinical practice, with a significant impact on patient
management.
Since 2004 the now discontinued PGDipEcho had nearly 460 graduates, with a few remaining
to complete. By the end of Semester 2 2011, approximately 450 students had graduated from
the new Certificate of Clinical Ultrasound, with 120 attaining the Diploma. By the end of 2013,
approximately 2000 students had completed workshops, about 1100 of which had completed
the limited transthoracic echocardiography course (HARTscan). Additionally about 500
delegates to conferences we have organised will have attended workshops. About 15-20% of
distance education students are international enrolments. For reference, in Australasia, there
are about 100 cardiothoracic surgeons, 250 cardiac anaesthetists, 750 cardiologists, 300
intensive care and 400 accident and emergency physicians. Overall we estimate that about
10% of all anaesthetists, more than 60% of all cardiac anaesthetists and 20% of intensive care
physicians have completed or are undertaking our courses.
a. Postgraduate Diploma of Perioperative and Critical Care
Echocardiography (PGDipEcho). This course was developed following early
use of transoesophageal echocardiography forcardiac surgery. I was one of the
pioneers of this technique in Australia. The key aim was to set up a
comprehensive education package to provide a diagnostic level knowledge base
for practitioners, utilising distance education technologies to make learning
easier. I led a steering committee and approximately 70 contributors from
Australia and overseas. This course has become the leading means for
anaesthesia and critical care specialists to learn echocardiography. The
PGDipEcho has now been replaced with a series of nested courses, designed to
cater better for the emerging non-cardiac anaesthesia craft groups. These
include Postgraduate Certificate, Diploma, and Masters levels of education.
b. Postgraduate Certificate of Clinical Ultrasound. All students start with this
course, as it teaches basic assessment skills using echocardiography and surface
CV Colin Royse
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ultrasound. The knowledge base will enable practitioners to become “good
basic sonographers” but without comprehensive diagnostic skills. This course is
designed principally for those beginning echocardiography, or for the non-
cardiac anaesthesia, emergency department, and intensive care specialties.
Ultimately other modular certificates with focus on musculoskeletal or vascular
sonography will be developed.
c. Postgraduate Diploma of Clinical Ultrasound. Students complete another
four subjects after the certificate course to obtain the diploma. The knowledge
base is extended to now provide diagnostic level skills and to focus on
transoesophageal echocardiography Our expectation is that approximately 50%
of the certificate students will continue and complete the diploma.
d. Masters of Clinical Ultrasound. This is now complete and released in 2014,
approximately 50 students are currently enrolled.
e. Hands-on Workshops. My echocardiography education group is also involved
in running a number of hands-on workshops and seminars. This started as a
means to provide hands-on experience for students who found it difficult to
obtain at their local institution. However these programs have become self-
standing, and have become important mechanisms for people wishing to start
doing echocardiography and ultrasound guided nerve blocks.
f. New developments. Our group has developed the Basic Perioperative TEE
program for the National Board of echocardiography in the USA. We have
currently enrolled 300 students. Another major development is to set up
education courses incorporating echocardiography simulators. The first two
courses in this series have been developed and tested in 2014. A new course
called “Basic TTE” is under development.
Collaborations
a. Sonosite Corporation: Sonosite has facilitated our teaching programs in point-of-
care ultrasound, and provided research equipment for our laboratory.
b. Co-Director of the steering committee of the Postgraduate Diploma of
Perioperative and Critical Care Echocardiography. The committee comprises 14
anaesthetists, intensive care physicians, or surgeons from across Australia and New
Zealand, who served to guide the progress of the diploma course.
c. Member of the international advisory board on the- postoperative quality of
recovery scale (PQRS). This scale will act as a research endpoint to measure
quality of recovery following anaesthesia and surgery. I am now the Chair of the
PQRS scientific committee.
d. Member of the advisory panel for the Australian and New Zealand College of
Anaesthetists, and the Joint Faculty of Intensive Care Medicine, which formulate
training guidelines for echocardiography and ultrasound use in anaesthesia and
critical care medicine.
e. Society of Cardiovascular Anesthesiology (SCA) collaboration: I have
successfully formed a partnership with the SCA, which is the most respected
organization in the USA concerning perioperative echocardiography. We are now
running our distance courses under license from The University of Melbourne for
the North American market. This has given us huge credibility outside of Australia
in the field of echocardiography education.
CV Colin Royse
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Clinical development in anaesthesia
My subspeciality interest is cardiac anaesthesia. I have been a pioneer in a number of
developments in this field. In 1995, I received formal training in transoesophageal
echocardiography and introduced it into the operating theatres at The Royal Melbourne
Hospital. The technology is now embraced in cardiac surgery and its application has extended
to other areas of anaesthesia.
In the mid-1990s, I pioneered the use of fast track anaesthesia for cardiac surgery at the Royal
Melbourne Hospital, including immediate extubation of patients in the operating theatre.
Whilst my practice has become more conservative, aiming for early rather than immediate
extubation, the process required many simultaneous changes in technique, including
anaesthetic agents, temperature management and pain control. This work is recognised
internationally, and I was invited to speak on it in 2008 at the International Congress of
Cardiovascular Anaesthesia.
I pioneered the use of epidural anaesthesia in cardiac surgery in Australia. This is an
emerging trend in many other countries. My aim is to improve pain management for patients
undergoing cardiac surgery. We have been performing the technique for over 15 years with
good results, and without complication in over 2000 cases. I have published the world’s third
largest clinical case series, and I am regarded as a world authority in the technique. I was
invited to write the “Current Opinion” review of the topic in 2008. I wrote an editorial for
Anesthesiology in 2011, and have lectured as a guest speaker on multiple occasions at
international meetings.
The focus of my clinical research now is the measurement of quality of recovery following
anaesthesia and surgery. I am a member of an international panel which has developed and
validated a new quality of recovery scale (PQRS – Postoperative Quality Recovery Scale). This
will provide a measurement tool to identify quality of recovery beyond the normal clinical
observation period (which for anaesthetists, is typically only a few hours). Studies
investigating quality of recovery in cardiac surgery are currently undergoing ethics
committee review.
Administrative/Management
I have set up and co-ordinate the “Postgraduate Diploma of Perioperative and Critical Care
Echocardiography”.The course represents a collaboration of experts in echocardiography
from Australia and New Zealand, and is administered through The University of Melbourne. I
co-administer administer 7 full time and 6 part time research or admin staff.
I set up the Anaesthesia and Pain Management Research Unit in 2006 within the Department
of Pharmacology. This was designed to be an umbrella organization for anaesthetists to seek
appointments with the university. The idea is to group anaesthetists into one unit, rather than
the current state where they are dispersed by being attached to surgical or medical
departments of their hospitals. It is critical for the development of anaesthesia as a discipline
to group individuals of common interest, so that research, education, and publication output
can be identified as belonging to the discipline of anaesthesia.
I am the only continuing University employed academic in anaesthesia, critical care and
emergency medicine. This indicates just how under resourced these specialties are.
Numerically, the critical care and anaesthesia craft groups are in the top five specialties yet
have almost no university representation. All other anaesthesia academics hold honorary
CV Colin Royse
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appointments. I have provided the co-ordination and mentoring for anaesthetists and other
critical care specialists to help them to realize their academic goals. In 2010, I provided
funding from the echocardiography programs for a 0.5 FTE position for an anaesthesia
lecturer. I intend to increase this as funds allow.
I served with the Australian Defence Force Reserves for 15 years, moving to inactive service
in 1998. I held a range of appointments culminating in “Officer Commanding, Medical
Company, 3BASB”. I participated in leadership courses and reached the rank of Substantive
Major. The management responsibility of a company-sized unit is 100 personnel, and the
organizational structure is similar to that of a department within a hospital.
Professional memberships / Boards
 Fellow of the Australian and New Zealand College of Anaesthetists
 Member of the Australian Society of Anaesthetists
 Member of the Australian Medical Association
 Medical Registration No. MPG227116
 AVANT Medical Defence Association No. 10278
Personal and leisure
I enjoy music, skiing and travel. I still play the piano, though my practice time is ever
diminishing with having teenage children. I am a real fan of classical music and opera.
Publications
Journal publications available in Pubmed
1. Callaway JK, Jones NC, RoyseAG, RoyseCF. Memory Impairment in Rats afterDesflurane
Anesthesiais Ageand Dose Dependent. Journal of Alzheimer'sdisease : JAD. 2014.
2. Vegas A, Denault A, RoyseC. A bedsideclinical andultrasound-basedapproachto
hemodynamic instability - Part II: bedside ultrasound in hemodynamic shock: Continuing
Professional Development. Canadian journal of anaesthesia = Journal canadien d'anesthesie.
2014;61(11):1008-27.
3. Denault A, Vegas A, RoyseC. Bedsideclinical andultrasound-based approaches to the
management of hemodynamic instability--part I: focus on the clinical approach: continuing
professional development. Canadian journal of anaesthesia = Journal canadien d'anesthesie.
2014;61(9):843-64.
4. Haji DL, Ali MM, RoyseA, Canty DJ, Clarke S, RoyseCF. Interatrial septum motion but not
Dopplerassessment predictselevated pulmonarycapillary wedgepressurein patientsundergoing
cardiac surgery. Anesthesiology. 2014;121(4):719-29.
5. Bowyer A, Jakobsson J, Ljungqvist O, RoyseC. A review ofthescopeand measurement of
postoperative quality ofrecovery. Anaesthesia. 2014;69(11):1266-78.
6. Canty DJ, Hayes JA, Story DA, Royse CF. Ultrasoundsimulator-assisted teaching of cardiac
anatomy to preclinical anatomy students:A pilot randomized trial of athree-hourlearning
exposure. Anatomical scienceseducation. 2014.
7. Liu J, Yuan W, Wang X, Royse CF, Gong M, Zhao Y, et al. Peripheral nerveblocks versus
general anesthesiafor total kneereplacement in elderlypatients onthe postoperative quality of
recovery. Clinical interventions in aging. 2014;9:341-50.
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8. Royse CF, WilliamsZ, YeG, Wilkinson D, DeSteigerR, RichardsonM, et al. Kneesurgery
recovery: Post-operative Quality of RecoveryScale comparison of ageandcomplexity ofsurgery.
Acta anaesthesiologica Scandinavica. 2014;58(6):660-7.
9. Royse CF, WilliamsZ, PurserS, Newman S. Recovery afternasal surgery vs. tonsillectomy:
discriminant validation of the Postoperative Quality ofRecoveryScale. Acta anaesthesiologica
Scandinavica. 2014;58(3):345-51.
10. Newman S, Wilkinson DJ, RoyseCF.Assessment of early cognitive recovery aftersurgery
using the Post-operative Quality of Recovery Scale. Acta anaesthesiologicaScandinavica.
2014;58(2):185-91.
11. Lindqvist M, RoyseC, Brattwall M, Warren-StombergM, Jakobsson J.Post-operative Quality
of Recovery Scale:the impact of assessment methodon cognitive recovery. Acta anaesthesiologica
Scandinavica. 2013;57(10):1308-12.
12. Royse CF, Newman S, Williams Z, Wilkinson DJ. A human volunteerstudy to identify
variability in performancein thecognitivedomainofthepostoperativequality of recovery scale.
Anesthesiology. 2013;119(3):576-81.
13. Soeding PF, Hoy S, HoyG, EvansM, RoyseCF. Effect ofphenylephrineonthe
haemodynamic state andcerebral oxygen saturation duringanaesthesiain theupright position.
British journal ofanaesthesia. 2013;111(2):229-34.
14. Griffiths JD, LeNV, Grant S, Bjorksten A, Hebbard P, Royse C. Symptomatic local anaesthetic
toxicity and plasma ropivacaineconcentrationsaftertransversus abdominis planeblock for
Caesarean section. British journal of anaesthesia. 2013;110(6):996-1000.
15. Haji DL, Royse A, RoyseCF. Review article: Clinical impact of non-cardiologist-performed
transthoracic echocardiography in emergency medicine, intensivecaremedicine andanaesthesia.
Emergency medicine Australasia: EMA. 2013;25(1):4-12.
16. Canty D, Royse C.A reply. Anaesthesia. 2013;68(2):207-8.
17. Udayasiri D, GangahanumaiahS, Royse C,RoyseA. Tricuspid valvepapillary muscle
avulsion from a pulmonary artery catheter. ANZjournal of surgery. 2012;82(12):939-40.
18. Royse CF, CantyDJ, FarisJ, Haji DL, VeltmanM, Royse A.Corereview:physician-performed
ultrasound: the time hascomeforroutine usein acute care medicine. Anesthesia andanalgesia.
2012;115(5):1007-28.
19. Canty DJ, RoyseCF, Kilpatrick D, BowyerA, Royse AG. The impact on cardiac diagnosis and
mortality of focusedtransthoracic echocardiographyin hip fracturesurgery patients with
increasedrisk ofcardiac disease: a retrospectivecohort study. Anaesthesia. 2012;67(11):1202-9.
20. Callaway JK, Jones NC, Royse AG, RoyseCF. Sevofluraneanesthesia does not impair
acquisition learningormemory in the Morris water maze in youngadult andagedrats.
Anesthesiology. 2012;117(5):1091-101.
21. Callaway JK, Jones NC, RoyseCF. Reply to: Isoflurane is not necessarily theonly cause of
cognitive deficits. European journal ofanaesthesiology. 2013;30(1):43-4.
22. Royse CF, Chung F, NewmanS, Stygall J, WilkinsonDJ. Predictors ofpatient satisfaction with
anaesthesia and surgery care: a cohort study usingthePostoperative Quality of Recovery Scale.
European journal of anaesthesiology. 2013;30(3):106-10.
23. Faris JG, Hartley K, FullerCM, LangstonRB, RoyseCF, Veltman MG. Audit of cardiac
pathologydetection usinga criteria-basedperioperativeechocardiography service. Anaesthesia
and intensive care. 2012;40(4):702-9.
24. Lam K, Canty D, RoyseC, RoyseA. Hospital survey of point-of-carelungultrasounduse in
the assessment ofperi-operativeandcritically ill patients. Critical care. 2012;16(3):437.
25. Dennis AT, Castro J, Carr C, Simmons S, Permezel M, Royse C. Haemodynamics in women
with untreatedpre-eclampsia. Anaesthesia. 2012;67(10):1105-18.
26. Royse CF, Haji DL, FarisJG, Veltman MG, KumarA, Royse AG. Evaluationofthe
interpretative skillsofparticipants of a limitedtransthoracicechocardiography training course
(H.A.R.T.scan course). Anaesthesia and intensivecare. 2012;40(3):498-504.
CV Colin Royse
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27. Canty DJ, RoyseCF, Kilpatrick D, Williams DL, RoyseAG. The impact of pre-operative
focusedtransthoracic echocardiographyin emergency non-cardiac surgery patientswith known
or risk of cardiac disease. Anaesthesia.2012;67(7):714-20.
28. Canty DJ, RoyseCF, Kilpatrick D, Bowman L, RoyseAG. The impact of focusedtransthoracic
echocardiographyin thepre-operativeclinic. Anaesthesia. 2012;67(6):618-25.
29. Callaway JK, Jones NC, RoyseCF. Isoflurane inducescognitivedeficits inthe Morris water
maze task in rats. European journal of anaesthesiology. 2012;29(5):239-45.
30. Andrews DT, Sutherland J, Dawson P, Royse AG, Royse C. L-argininecardioplegia reduces
oxidative stress and preservesdiastolic function in patients with low ejection fraction undergoing
coronaryartery surgery. Anaesthesia andintensivecare. 2012;40(1):99-106.
31. Andrews DT, RoyseC, Royse AG. The mitochondrial permeability transition poreandits
role in anaesthesia-triggeredcellularprotectionduringischaemia-reperfusioninjury. Anaesthesia
and intensive care. 2012;40(1):46-70.
32. Ali MM, Royse AG, Connelly K, RoyseCF. The accuracy oftransoesophageal
echocardiographyin estimatingpulmonary capillary wedge pressure in anaesthetisedpatients.
Anaesthesia. 2012;67(2):122-31.
33. Soeding PF, Wang J, Hoy G, JarmanP, Phillips H, Marks P, et al. The effect ofthe sitting
upright or'beachchair'position on cerebral bloodflow duringanaesthesiaforshoulder surgery.
Anaesthesia and intensive care. 2011;39(3):440-8.
34. Brooks M, RoyseC, Eisen D, Sparks P, Bhagwat K, RoyseA. An accidental mass. Lancet.
2011;377(9779):1806.
35. Royse CF, Andrews DT, Newman SN, Stygall J, WilliamsZ, PangJ, et al. The influenceof
propofol ordesflurane on postoperative cognitivedysfunction in patients undergoingcoronary
artery bypass surgery. Anaesthesia.2011;66(6):455-64.
36. Faris JG, Veltman MG, RoyseC. Focusedtransthoracic echocardiography in the
perioperative period. Anaesthesiaandintensivecare. 2011;39(2):306-7; author reply 7-8.
37. Royse CF, Ruizhi N, HuynhAL,RoyseAG. The Effect of a Hyperdynamic Circulation on
Tissue DopplerValues: A Simulation in Young Adultsduring Exercise. Anesthesiology research and
practice. 2011;2011:165874.
38. Connelly KA, Royse C, RoyseAG. Tissue DopplerEm andinstantaneous end-diastolic
stiffness: validationagainst pressure-volumeloops in patients undergoingcoronary artery bypass
surgery. Heart, lung& circulation. 2011;20(4):223-30.
39. Royse C. Epiduralsfor cardiac surgery: can wesubstantially reducesurgical morbidity or
should we focus on quality of recovery? Anesthesiology. 2011;114(2):232-3.
40. Soeding PF, Crack PJ, Wright CE, Angus JA, RoyseCF. Levosimendanpreserves the
contractile responsiveness ofhypoxic humanmyocardium viamitochondrial K(ATP)channel and
potential pERK 1/2activation. Europeanjournal ofpharmacology. 2011;655(1-3):59-66.
41. Conaglen PJ, Ellims A, RoyseC, Royse A. Acuterepair oftraumatictricuspid valve
regurgitationaided by three-dimensional echocardiography. Heart, lung& circulation.
2011;20(4):237-40.
42. Griffiths JD, Barron FA, Grant S, BjorkstenAR, HebbardP, Royse CF. Plasmaropivacaine
concentrations after ultrasound-guidedtransversus abdominis planeblock. British journal of
anaesthesia. 2010;105(6):853-6.
43. MacLaren G, KlugerR, Connelly KA, Royse CF. Comparativefeasibility of myocardial
velocity and strain measurements using2 different methodswith transesophageal
echocardiographyduringcardiac surgery. Journal of cardiothoracic andvascularanesthesia.
2011;25(2):216-20.
44. Royse CF, Newman S, Chung F, Stygall J, McKay RE, Boldt J, et al. Development and
feasibility ofa scale to assesspostoperativerecovery: thepost-operativequality recovery scale.
Anesthesiology. 2010;113(4):892-905.
CV Colin Royse
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45. Griffiths JD, Middle JV, BarronFA, Grant SJ, Popham PA, Royse CF. Transversus abdominis
plane block does not provide additional benefit to multimodal analgesiain gynecological cancer
surgery. Anesthesia and analgesia. 2010;111(3):797-801.
46. HebbardPD,RoyseCF. Lack of efficacywith transversus abdominis planeblock: isit the
technique, theend points, or thestatistics?Regional anesthesia andpainmedicine.
2010;35(3):324.
47. Dennis A, Arhanghelschi I, Simmons S,RoyseC. Prospectiveobservational studyofserial
cardiac output by transthoracic echocardiography in healthypregnant women undergoingelective
caesarean delivery. International journal ofobstetric anesthesia. 2010;19(2):142-8.
48. BourneE, Wright C,RoyseC. A review oflocal anesthetic cardiotoxicity and treatment with
lipid emulsion. Local and regional anesthesia. 2010;3:11-9.
49. Royse CF. Isa different dose ofanesthesia thereal problem?Anesthesia and analgesia.
2009;109(6):2031-2; authorreply 2.
50. Royse CF. Anaesthesia in septic patients: good preparationandmakingtheright choice?
Critical care. 2009;13(6):1001.
51. Royse AG, RoyseCF. Epiaortic ultrasoundassessment ofthe aortain cardiac surgery. Best
practice & researchClinical anaesthesiology. 2009;23(3):335-41.
52. Faris JG, Veltman MG, RoyseCF. Limited transthoracic echocardiography assessment in
anaesthesia and critical care.Best practice & research Clinical anaesthesiology. 2009;23(3):285-
98.
53. Royse CF. Ultrasound-guided haemodynamic state assessment. Best practice& research
Clinical anaesthesiology. 2009;23(3):273-83.
54. Royse CF. Ultrsasound in anaesthesiology andintensive care. Preface. Best practice &
research Clinical anaesthesiology. 2009;23(3):vii.
55. Andrews DT, RoyseAG, RoyseCF. Functional comparison of anaesthetic agents during
myocardial ischaemia-reperfusion usingpressure-volume loops. British journal of anaesthesia.
2009;103(5):654-64.
56. Royse CF. High thoracic epidural analgesia forcardiac surgery: time to movefrom
morbidity to quality ofrecoveryindicators. Annalsofcardiac anaesthesia. 2009;12(2):168-9;
author reply70-1.
57. Canty DJ, RoyseCF. Audit ofanaesthetist-performedechocardiography on perioperative
management decisions fornon-cardiac surgery. British journal of anaesthesia. 2009;103(3):352-8.
58. Royse CF. High thoracic epidural anaesthesia forcardiac surgery. Current opinion in
anaesthesiology. 2009;22(1):84-7.
59. Royse CF, BirdH, Royse AG. Routine assessment of coeliac axis andrenal artery flow is not
feasible with transoesophageal echocardiography. Anaesthesia. 2009;64(1):103-4.
60. AlsaddiqueAA, RoyseAG, RoyseCF, Fouda MA. Management of diastolic heart failure
following cardiac surgery. Europeanjournal of cardio-thoracic surgery : official journal of the
European AssociationforCardio-thoracic Surgery. 2009;35(2):241-9.
61. HebbardP, Royse C. Audit of transverseabdominus plane block foranalgesia following
caesarean section. Anaesthesia.2008;63(12):1382.
62. Royse C. Ultrasound education in anaesthesia:turningthe tables on convention. Annalsof
cardiac anaesthesia. 2008;11(2):77-9.
63. Royse AG, Chang GS, NicholasDM, Royse CF. No lateulnarartery atheroma after radial
artery harvest forcoronaryartery bypasssurgery. TheAnnalsofthoracic surgery.
2008;85(3):891-4.
64. Royse CF, Liew DF, Wright CE, Royse AG, AngusJA. Persistent depressionofcontractility
and vasodilation with propofol but not with sevoflurane ordesflurane in rabbits. Anesthesiology.
2008;108(1):87-93.
65. Soeding PE, Royse CF, Wright CE,RoyseAG, AngusJA. Inoprotection: theperioperativerole
of levosimendan. Anaesthesia and intensivecare. 2007;35(6):845-62.
CV Colin Royse
13
66. HebbardP, Fujiwara Y,ShibataY, RoyseC. Ultrasound-guided transversusabdominisplane
(TAP) block. Anaesthesia and intensive care. 2007;35(4):616-7.
67. Royse AG, RoyseCF. ICVTSon-linediscussion B Radial artery harvest preserves forearm
blood flow. Interactivecardiovascular andthoracic surgery. 2007;6(5):602.
68. Royse A, RoyseC. A standardisedintraoperativeultrasoundexamination of theaorta and
proximal coronary arteries. Interactive cardiovascularand thoracic surgery. 2006;5(6):701-4.
69. Royse CF, Soeding PF, Royse AG. Highthoracic epidural analgesiafor cardiac surgery: an
audit of 874cases. Anaesthesiaandintensivecare. 2007;35(3):374-7.
70. Royse C. Is depthofanesthesia, as assessedby the bispectral index, related to postoperative
cognitive dysfunction and recovery?Anesthesia and analgesia. 2007;104(5):1297; author reply -8.
71. HebbardP, Royse C. Ultrasoundguidedposteriorapproach to the infraclavicularbrachial
plexus. Anaesthesia. 2007;62(5):539.
72. Royse CF, RoyseAG, RohrlachR, Wright CE, Angus JA. Thecardiovascular effectsof
adrenaline, dobutamine andmilrinone in rabbitsusing pressure-volume loopsandguineapig
isolated atrial tissue.Anaesthesia andintensivecare.2007;35(2):180-8.
73. Royse C, RemediosC, Royse A. High thoracic epidural analgesiareduces therisk oflong-
term depressionin patientsundergoing coronary artery bypass surgery. Annalsofthoracicand
cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons
of Asia. 2007;13(1):32-5.
74. Royse CF, Connelly KA, MacLaren G, RoyseAG. Evaluation ofechocardiography indicesof
systolic function: a comparativestudy usingpressure-volumeloops in patients undergoing
coronaryartery bypasssurgery. Anaesthesia. 2007;62(2):109-16.
75. Royse CF, Seah JL, Donelan L, Royse AG. Point of care ultrasound forbasichaemodynamic
assessment: novicecompared with an expert operator. Anaesthesia. 2006;61(9):849-55.
76. Maclaren G, KlugerR, Prior D, Royse A, RoyseC. Tissue Doppler, strain, andstrain rate
echocardiography: principlesandpotential perioperativeapplications. Journal ofcardiothoracic
and vascular anesthesia. 2006;20(4):583-93.
77. Royse CF, Hall J, RoyseAG. The 'mesentery' dressing for epidural catheterfixation.
Anaesthesia. 2006;61(7):713.
78. Royse CE, ShaS, Soeding PF, Royse AG. Anatomical study ofthebrachial plexususing
surface ultrasound. Anaesthesia andintensivecare. 2006;34(2):203-10.
79. Soeding PE, Sha S, RoyseCE, Marks P, Hoy G, RoyseAG. A randomizedtrial ofultrasound-
guided brachial plexus anaesthesia in upperlimb surgery.Anaesthesia andintensivecare.
2005;33(6):719-25.
80. King G, FoleyJB, RoyseCF, Yastrebov K,Hussey M, BoyleG, et al. Myocardial stiffness and
the timing difference betweentissue Dopplerimaging Ea andpeak mitral valveopeningcan
distinguish physiological hypertrophy in athletes from hypertrophic cardiomyopathy. European
journal of echocardiography: the journal of theWorkingGroup on Echocardiographyofthe
European Society of Cardiology. 2006;7(6):423-9.
81. Royse CE, Royse AG, Deelen DA. Anaudit of morphine versusfentanyl as anadjunct to
ropivacaine 0.2% forhigh thoracic epidural analgesia. Anaesthesiaandintensivecare.
2005;33(5):639-44.
82. Royse CF, RoyseAG. The myocardial andvasculareffects of bupivacaine, levobupivacaine,
and ropivacaine usingpressurevolumeloops. Anesthesiaandanalgesia. 2005;101(3):679-87,
table of contents.
83. ChakravarthyM, Nadiminti S, KrishnamurthyJ, Thimmannagowda P, Jawali V, Royse CF, et
al. Temporary neurologic deficits in patients undergoing cardiac surgery with thoracic epidural
supplementation. Journal of cardiothoracicandvascularanesthesia. 2004;18(4):512-20.
84. Royse CF, RoyseAG, BharatulaA, Lai J, Veltman M, Cope L, et al. Substernal epicardial
echocardiography: a recommendedexamination sequenceandclinical evaluation in patients
undergoingcardiac surgery. The Annals of thoracic surgery. 2004;78(2):613-9; discussion9.
CV Colin Royse
14
85. Royse AG, RoyseCF, MaleskarA, Garg A. Harvest of the radial artery for coronaryartery
surgerypreserves maximal bloodflow of theforearm. The Annals of thoracic surgery.
2004;78(2):539-42.
86. Royse AG, RoyseCF, WongCT. Graft flow increases with release of stabilizing devicein off-
pump coronarysurgery. Annals of thoracic and cardiovascularsurgery : official journal of the
AssociationofThoracicandCardiovascularSurgeonsofAsia. 2003;9(6):384-8.
87. Royse CF, RoyseAG, WongCT. Assessment of left ventricular functionduring off-pump
coronaryartery bypasssurgery. Annalsof thoracic andcardiovascularsurgery : official journal of
the AssociationofThoracic andCardiovascular Surgeons of Asia. 2003;9(6):371-7.
88. Royse CF, RoyseAG, Soeding PF, Mathieson EM. Descending aortic pulsed wave Doppler
can predict changes in cardiacoutput duringoff-pumpcoronary arterybypass surgery.Annals of
thoracic and cardiovascularsurgery : official journal of theAssociationofThoracic and
CardiovascularSurgeons of Asia. 2003;9(5):314-8.
89. Blake DW, RoyseCF, Royse AG, Bjorksten AR, SoedingPF, PangJ. Alfentanil infusion asa
component ofintravenous anaesthesia forcoronary arterybypass surgerywith "fast-track"
recovery. Anaesthesia and intensive care. 2003;31(2):181-3.
90. Royse CF, RoyseAG, WongCT, Soeding PF. Theeffect ofpericardial restraint, atrial pacing,
and increasedheart rate on left ventricularsystolicanddiastolic function in patients undergoing
cardiac surgery. Anesthesia andanalgesia. 2003;96(5):1274-9, table of contents.
91. Royse C, RoyseA, SoedingP, Blake D, Pang J. Prospective randomized trial of high thoracic
epidural analgesia forcoronary arterybypass surgery. The Annals of thoracic surgery.
2003;75(1):93-100.
92. Ho SC, Royse CF, Royse AG, PenberthyA, McRaeR. Persistent painaftercardiac surgery:an
audit of highthoracic epidural and primaryopioidanalgesiatherapies. Anesthesia andanalgesia.
2002;95(4):820-3, table of contents.
93. Royse CF, RoyseAG, Soeding PF, Blake DW.Shapeandmovement of the interatrial septum
predicts change in pulmonarycapillary wedgepressure. Annalsofthoracic andcardiovascular
surgery: official journal ofthe Association of Thoracic and CardiovascularSurgeonsofAsia.
2001;7(2):79-83.
94. Royse C, Soeding P, RoyseA. Immediateorearly extubation:wheredo we start?Anesthesia
and analgesia. 2001;92(4):1073-4.
95. Royse CF, RoyseAG. Afterload corrected fractional areachange(FACac):a simple, relatively
load-independent measurement ofleft ventricular contractility in humans. Annalsof thoracic and
cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons
of Asia. 2000;6(5):345-50.
96. Purser S, RoyseCF, VelkovHA, Roberts LF. Topical application of ethanol to the tonsillar
bed immediately following tonsillectomy does not improvepost-operativeanalgesia. The Journal
of laryngology and otology. 2000;114(9):671-4.
97. Royse CF, RoyseAG, BlakeDW, GriggLE.Instantaneous end diastolicstiffness (IEDS): a
simple, load independent measurement ofleft ventriculardiastolic function inpatients undergoing
cardiac surgery. Annals of thoracic and cardiovascularsurgery : official journal of theAssociation
of Thoracic and CardiovascularSurgeons of Asia. 2000;6(3):203-10.
98. Royse AG, RoyseCF, Ajani AE, Symes E, Maruff P, Karagiannis S, et al. Reduced
neuropsychological dysfunction usingepiaortic echocardiography and theexclusiveY graft. The
Annals of thoracic surgery. 2000;69(5):1431-8.
99. Royse CF, Barrington MJ, Royse AG. Transesophageal echocardiography values forleft
ventricularend-diastolic area and pulmonary veinandmitral inflow Dopplervelocitiesin patients
undergoingcoronary artery bypassgraft surgery. Journal ofcardiothoracic and vascular
anesthesia. 2000;14(2):130-2.
CV Colin Royse
15
100. Royse AG, RoyseCF, Tatoulis J, Grigg LE, ShahP, Hunt D, et al. Postoperativeradial artery
angiography forcoronary arterybypass surgery.European journal of cardio-thoracic surgery :
official journal of the European Associationfor Cardio-thoracic Surgery. 2000;17(3):294-304.
101. Macguire B,RoyseC, Royse A, DuaneM, PangJ. Lungfunction followingcardiac surgeryis
not affected by postoperativeventilation time. Annals of thoracic and cardiovascularsurgery :
official journal of the AssociationofThoracicandCardiovascular Surgeons ofAsia. 2000;6(1):13-8.
102. Royse CF, RoyseAG, BlakeDW, GriggLE.Measurement ofcardiac output by
transoesophageal echocardiography: a comparisonoftwo Dopplermethods with thermodilution.
Anaesthesia and intensive care. 1999;27(6):586-90.
103. Royse AG, RoyseCF, Tatoulis J. Total arterial coronary revascularization and factors
influencing in-hospital mortality. Europeanjournal ofcardio-thoracic surgery : official journal of
the EuropeanAssociation for Cardio-thoracic Surgery. 1999;16(5):499-505.
104. Royse AG, RoyseCF, GrovesKL, BusB, YuG. Bloodflow in compositearterial graftsand
effect of nativecoronary flow. TheAnnalsofthoracicsurgery. 1999;68(5):1619-22.
105. Royse AG, RoyseCF, Raman JS. Exclusive Y graft operation formultivessel coronary
revascularization. TheAnnalsofthoracic surgery. 1999;68(5):1612-8.
106. Royse CF, RoyseAG, Soeding PF. Routine immediateextubation after cardiacoperation: a
review of ourfirst 100 patients. TheAnnalsofthoracic surgery. 1999;68(4):1326-9.
107. Royse CF, RoyseAG, BlakeD, Grigg LE. Aortic valve area: measurement by transesophageal
echocardiographyandprediction byleft ventricularoutflow tract area. Annals ofthoracic and
cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons
of Asia. 1999;5(3):168-73.
108. Royse AG, RoyseCF, Shah P, Williams A, Kaushik S, Tatoulis J. Radial artery harvest
technique, use andfunctional outcome. European journal of cardio-thoracicsurgery : official
journal of theEuropeanAssociation for Cardio-thoracic Surgery. 1999;15(2):186-93.
109. Royse C, RoyseA, Blake D, GriggL.Screeningthethoracic aortafor atheroma: a comparison
of manual palpation, transesophageal andepiaortic ultrasonography. Annals of thoracic and
cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons
of Asia. 1998;4(6):347-50.
110. Royse C, RoyseA, Blake D, GriggL.Assessment of thoracic aortic atheroma by
echocardiography: a new classification andestimationofrisk ofdislodgingatheroma during three
surgical techniques. Annals of thoracic and cardiovascularsurgery : official journal of the
AssociationofThoracicandCardiovascularSurgeonsofAsia. 1998;4(2):72-7.
111. Royse CF, Tiernan RJ, Portelli SM, DaviesS, ArblasterR, Bjorksten AR, et al. Theeffect of
supplemental oxygenonthe incidenceofhypoxaemiaafterpremedication in patients undergoing
cardiac surgery. Anaesthesia and intensive care. 1997;25(4):347-9.
112. Dawson PJ, Libreri FC, JonesDJ, Libreri G, Bjorkstein AR, RoyseCF. Theefficacy of adding a
continuous intravenous morphine infusion to patient-controlledanalgesia (PCA) in abdominal
surgery. Anaesthesiaand intensivecare. 1995;23(4):453-8.
113. HebbardGS,RoyseCF, Bjorksten AR.Oxygen supplementation during upper
gastrointestinal endoscopy: a comparisonoftwo methods. Endoscopy. 1994;26(3):278-82.
CV Colin Royse
16
Grants and other teaching/research income
The table below lists grants received.
Type of grant: CG = national competitive grant; IG = industry grant; T = teaching income
%CR = % of the grant designated for me for competitive grants. Education income is shared
between myself and my laboratory co-director (Alistair Royse-AR).
Org is the organization or funding body.
[CR-PI] indicates where I am the principal investigator for the particular project.
Year
s
Title Org Type Amount $ %CR
2014 NHMRC NHMRC CG $709,000 10% (CIE)
2014 NIH Trajectory of Recovery in the
Elderly (TORIE) NIH
1R01AG046634-01A1
NIH CG 1,000,000 5%
(consultant)
2012 NMHRC grant (CIB) - The impact
of anaesthesia and inflammation of
cognition
NRMRC CG 280,000 40% (CIB)
2011 ANZCA Academic Enhancement
Grant: The impact of anaesthesia
and inflammation of cognition
ANZCA CG 90,000 100 (CIA)
2010 When is anaesthesia detrimental
and when is it protective
NHF CG 124,000 50% (CIA)
2009 Quality of recovery following knee
surgery
Baxter IG 189,000 100% (CR-PI)
2007 Validation of Tissue Doppler Strain
against pressure volume loops in
Pigs
ANZCA CG 48,000 70%
2007 A randomized trial of propofol
versus desflurane on the
development of cognitive decline
following CABG
Baxter IG 400,000 CR-PI
(70%)
2007 Investigation of the cardiovascular
effects of anaesthetics using
pressure volume loops
Baxter IG 80,000 CR-PI
(70%)
2005 The effects of bleeding on
economic cost and morbidity in
patients undergoing cardiac
surgery
NovoN
ordisk
IG 50,000 CR-PI
(60%)
2004 Evaluation of the Sonosite Titan
portable ultrasound machine
Sono-
site
IG 20,000 [CR-PI]
(70%)
2003 Evaluation of echocardiography
indices of left ventricular function
using pressure volume loops
CVL CG 25,000 50%
2003 Evaluation of levosimendan using ASA CG 40,000 80%
CV Colin Royse
17
pressure volume loops
2003 Comparison of the cardiotoxic
effects of bupivacaine
levobupivacaine and ropivacaine
in a rabbit model using pressure
volume loops
CASS CG 25,000 80%
2003
-
2004
A randomised trial of
cardiopulmonary bypass for
coronary artery surgery
NHF CG 99,000 50%
2002 Comparison of the cardiotoxic
effects of bupivacaine
levobupivacaine and ropivacaine
in a rabbit model using pressure
volume loops
Astra
Zeneca
IG 20,000 [CR-PI]
(70%)
2002 Evaluation of left ventricular
function and graft flows during of
pump coronary artery surgery
Edward
Dunlop
CG 15,000 [AR-PI]
(30%)
2002 Estimation of LVEDP using
transoesophageal
echocardiography
ASA CG 10,000 70%
2001 Epidural use in cardiac surgery Astra
zeneca
IG 10,000 [CR-PI]
(80%)
2001 Validation of simple indices of left
ventricular function using
echocardiography
Winder
-mere
CG 10,000 80%
2001 Validation of simple indices of left
ventricular function using
echocardiography
Perpert
Found
CG 10,000 80%
2001 Validation of simple indices of left
ventricular function using
echocardiography
ASA CG 10,000 80%
2001 Equipment grant to purchase CFL
512 cardiac function analyser to
perform pressure volume loops
UoM CG 55,000 80%
2001 Equipment grant to purchase CFL
512 cardiac function analyser
Ramma
-cciotti
CG 25,000 80%
2001 Equipment grant to purchase CFL
512 cardiac function analyser
Med-
tronic
IG 10,000 [CR-PI]
(60%)
2001 Equipment grant to purchase CFL
512 cardiac function analyser
AMC IG 5,000 [CR-PI]
(50%)
2000
-
2001
A randomised trial of epidural use
in cardiac surgery
NHF CG 99,000 [CR-PI] 70%
2000 A randomised trial of epidural use
in cardiac surgery
ASA CG 10,000 70%
2000 A randomised trial of epidural use
in cardiac surgery
Astra
Zeneca
IG 10,000 [CR-PI]
(70%)
1998
-
1999
Postgraduate research scholarship NHMRC CG 48,000 100%
CV Colin Royse
18
National and international presentations.
I deliver national or international presentations > 5 time per year, with the majority ion
recent years being international presentations as an invited speaker.
Presentations for the last 3 years are shown below:
1. National. Invited speaker: Postoperative Quality of Recovery - are we doing a good job?
ANZCA, ASM; Perth, Australia 2012.
2. National. Invited speaker: Utility of rapid scanning (goal focused) echocardiography.
ANZCA ASM; Perth Austalia 2012.
3. International. Invited speaker: Horses for courses: different inotropes for different
disease states. Cardiothoracic & Intensive Care Symposium; Argentina 2012.
4. International. Invited speaker: Basic haemodynamic state assessment. World Congress
of Anesthesiology; Argentina 2012.
5. International. Invited speaker: CVC-PA versus echo: Pro-con debate. World Congress
of Anesthesiology; Argentina 2012.
6. International. Postoperative quality of recovery: Data presentaiton from studies using
the PQRS. World Congress of Anaesthesiology; Argentina 2012.
7. International. Basic TEE assessment of the Mitral Valve. American Society of
Anesthesiology; Chicago, USA 2012.
8. International. Keynote speaker: Postoperative Quality of Recovery: the new horizon for
anaestheia. 2011 International Basic and Clinical Research Forum of Anesthesia; Xian, China
2012.
9. International. Invited speaker: Postoperative quality of recovery: are we doing a good
job. European Society of Anaesthesia; Paris, France 2012.
10. International. Invited speaker: Echo to the rescue. International Congress of
Cardiothoracic and Vascular Anesthesia (ICCVA); Auckland, NZ 2012.
11. National. Invited speaker: Transthoracic Echocardiography in non-cardiac surgery.
The ULTRA Meeting - ANZCA; Melbourne, Australia 2012.
12. National. Keynote speaker: Ultrasound for everyone - how ultrasound is changing
clinical practice. ANZCA ASM; Melbourne, Aust 2013.
13. National. Keynote speaker: The limitations of Evidence based medicine. ANZCA ASM;
Melbourne, Aust 2013.
14. National. Keynote speaker: Measureing quality of recovery. ANZCA ASM; Melbourne,
Australia 2013.
15. International. Invited speaker: Rescue TEE. American Society of Anesthesiology; Sann
Francisco, USA 2013.
16. International. Invited Speaker: Focused Cardiac Ultrasound. 10th Meeting of Asian
Society of Cardiothoracic Anesthesiologists; Singapore 2013.
17. International. Invited Speaker: Postoperative cognitive dysfunction and effects on the
developing brain. European Society of Anaesthesiology; Madrid, Spain 2013.
18. International. Keynote speaker: Postoperative Quality of Recovery: The new horizon in
Anaesthesia practice. Annual Scientific Meeting in Anaesthesiology (Hong Kong Society of
Anaesthesia); Hong Kong 2013.
19. International. Keynote speaker: Ultrasound for everyone - the new horizon for
anaestehsia practice. Annual Scientific Meeting in Anaesthesiology (Hong Kong Society of
Anaesthesia) 2013.
20. International. Keynote speaker: Ultrasound para todos - how ultrasound is changing
clincal practice. Congreso Chileno de Anesthsiologica; Chile 2013.
CV Colin Royse
19
21. International. Keynote speaker: Postoperative Quality of Recovery scale:
Hacia un Nuevo Score de Alta Post Anestesia. Congreso Chileno de Anesthsiologica; Chile
2013.
22. International. Invited speaker: Should basic TEE be in the core curriculum of
anesthesiology residency training? American Society of Anesthesiology; New Orleans, USA
2014.
23. International. Keynote speaker: Ultrasound for everyone
–the new horizon for anesthesia and critical care practice. The 5th Visual Technology
Medical Conference in Anaesthesia/Pain/Critical Care/Emergency; China 2014.
24. International. Grand Round: Postoperative Quality of Recovery:
The new horizon in anaesthesia practice. Grand Round; Mt Sanai, New York, USA 2014.
25. International. Keynote speaker: Ultrasound for everyone
–the new horizon for clinical ultrasound. 14th Annual Scientific Session of Chinese Society of
Ultrasound in Medicine Suzhou, China 2014.
26. International. Invited speaker: Ultrasound for everyone
–the new horizon for anesthesia and critical care practice. Chinese Society of Anesthesiology
annual scientific meeting; Chengdu, China 2014.
27. International. Keynote speaker: Estimating ventricular volume. 11th Annual
International Symposium on Ultrasound and Regional Anesthesia 2014; Toronto, Canada
2014.
28. International. Keynote speaker: Perioperative TTE applications in anesthesia and
critical care practice. 11th Annual International Symposium on Ultrasound and Regional
Anesthesia 2014; Toronto, Canada 2014.
29. International. Invited Speaker: Outcomes for the Anaesthetist. Enhanced Recovery
After Surgery; Valencia, Spain 2014.

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CV colin Royse November 2014

  • 1. Part E. LEVEL 6 Clinical Medical Research Building, The Royal Melbourne Hospital Post: PO Box 2135, RMH, Victoria, 3050 P: +61383445673 M: +61408467548 F: +61386794445 E: colin.royse@unimelb.edu.au September 14 Curriculum Vitae Colin Royse, MBBS, MD, FANZCA Professor The University of Melbourne Department of Surgery Consultant Anaesthetist The Royal Melbourne Hospital
  • 2. CV Colin Royse 2 Personal Details DOB: 7 May 1964 Married to Carolyn Royse, 2 children, Cameron and Georgia Tel: 0408467548 e-mail: colin.royse@unimelb.edu.au Qualifications 2000 Doctorate of Medicine (by thesis), The University of Melbourne: “Applications of echocardiography in cardiac surgery and anaesthesia” 1996 Fellow of the Australian and New Zealand College of Anaesthetists 1987 Bachelor of Medicine, Bachelor of Surgery, The University of Melbourne 1981 Higher School Certificate, Melbourne High School Academic Appointments 2010- Promoted to Level E, full time continuing. Co-Director of the Ultrasound Education Unit, Department of Surgery 2006-2010 Level D Full-time continuing appointment, Head, Anaesthesia and Pain Management Unit, Department of Pharmacology 2004-2006 Level D @0.5FTE, Department of Pharmacology Executive, Cardiovascular Therapeutics Unit 2002 Principal Fellow, Department of Pharmacology 2000 Senior Fellow, Department of Pharmacology, The University of Melbourne. Head Human Cardiovascular Research Laboratory. 1996-1999 Doctorate of Medicine student Clinical appointments 1996 - Consultant Anaesthetist The Royal Melbourne Hospital, 1996- P.A.N.C.H. 1996 St. Vincent’s Hospital, 1996-7 1991-1996 Anaesthesia Registrar The Royal Melbourne Hospital Albury Base Hospital The Royal Women’s Hospital The Royal Children’s Hospital 1988 -1991 Hospital Medical Officer Austin Hospital, Bendigo Base Hospital and The Royal Melbourne Hospital
  • 3. CV Colin Royse 3 Research appointments 2012 Director, Anaesthesia and Pain Management Unit, Department of Surgery, and Co-director, Ultrasound Education Group. 2006 Director, Anaesthesia and Pain Management Unit, Department of Pharmacology Commenced animal based research in addition to clinical research. 2005 Executive, Cardiovascular Therapeutics Unit, Department of Pharmacology 2000 Laboratory head, Human Cardiovascular Research Laboratory, Department of Pharmacology. Research In 1995, I was one of the first Australian anaesthetists to learn and perform transoesophageal echocardiography for cardiac anaesthesia. I followed this clinical pioneering practice with research designed to validate its use and to investigate new areas for which it could be useful. The applications of echocardiography and surface ultrasound use have increased since then and I have pioneered the use of these technologies in non-cardiac anaesthesia, nerve blocks and vascular access. Research projects have mirrored these innovations. I have also been involved in research for surgical innovations and these often overlap with innovations in anaesthesia. My interests in ventricular function led me to want to validate new echocardiography measurement techniques against the gold-standard invasive techniques that are mostly only performed in animal preparations. This was the impetus to set up an animal laboratory at The University of Melbourne and to invest in pressure-volume loop equipment (my lab is one of the few in the country with this technology). What followed was a growing interest in anaesthetic pharmacology and the area of organ protection. This has led back to human clinical research where I carried out a randomized trial of anaesthetic agents, looking at brain protection. I am now involved in a number of multicentre clinical trials of outcome in cardiac surgery. What started as pure clinical research has therefore moved to the laboratory and now again to human research, and is a good example of “bench-bedside” translational research. In this journey, I have supervised many students (see below) and engaged anaesthetists in research higher degree training. I now supervise or co-supervise more anaesthetists doing higher degree research than any other anaesthetist in Australia. Productivity in relation to opportunity My career citations are > 2000, and I have published >130 peer- reviewed papers and book chapters, with more than 25% in the leading journals of the discipline. One hundred and thirteen are in indexed journals, and I currently publish 8-10 papers per year with half as first or senior author. Most of my research time in the past was “honorary”, and completed while I was working full time in clinical practice. It is only since late 2006 that I have been full time teaching and research. In 2005 I had six months absence whilst receiving treatment for a serious illness, and it took a further six months to return to full research capacity. I also spent most of my time in 2003 and 2004 developing the Postgraduate Diploma of Perioperative and Critical Care Echocardiography. This was such an enormous task, that I had to reduce my research commitment. I believe that my productivity has been outstanding, and more remarkable given the limited opportunity.
  • 4. CV Colin Royse 4 Interests a. Cardiovascular and neurological effects of anaesthesia in animals. There is a range of research preparations in the Cardiovascular Therapeutics Unit, including organ bath and myograph in-vitro preparations, anaesthetized animal preparations, and pressure-volume loop preparations in rats, rabbits and pigs. This last technology, which is only available in a few labs in Australia and world wide, allows direct measurement of contractility. These preparations are supplemented by histology and molecular techniques provided by collaborators. These techniques have been used to investigate the cardiovascular effects of anaesthetics, novel inotropes, cardioprotection and safety pharmacology especially with local anaesthetics. A new area of research is studying the neurotoxicity of anaesthetics in rats using cognitive function testing. This important development will complement human clinical research in this area. I received an ANZCA academic enhancement grant for 2012 to further develop this research and to build capacity in basic science research for Anaesthesia. I have closed my lab in Pharmacology due to a move to Department of Surgery, but I am still engaged with collaborators. b. Echocardiography Validation of echocardiography measurements is being carried out in animals and humans. , Animal and human volunteer studies are investigating the accuracy of Tissue Doppler Velocity measurements of systolic and diastolic function. These approaches hold great promise as the measurements are simple to perform and non-invasive The new horizon in echocardiography is 3-dimensional real time echocardiography, and several studies validating its use have commenced. At the lower end of technology, the use of limited transthoracic echocardiography as a real time clinical diagnostic and monitoring tool is being investigated in the preoperative assessment clinic, and in the emergency department. These studies focus on how the echocardiography scan influences clinical management decisions. I am currently investigating the validity of echocardiography assessment of left and right atrial pressure in awake and anaesthetized patients using transthoracic and transoesophageal echocardiography. I am also conducting research into echocardiography education, especially with simulation technologies. c. Human organ protection during cardiac surgery I was the principal investigator in a trial comparing the effects of two anaesthetic agents on the incidence of postoperative cognitive dysfunction (POCD) after cardiac surgery. This human study mirrored the animal investigations on the balance between potential neurotoxicity caused by anaesthetics versus the potential neuroprotective effects during a period of potential organ injury, such as occurs during cardiac surgery. I am an investigator in a multicentre trial investigating the effect of high-dose steroids in cardiac surgery, and in blood transfusion strategies. d. Recovery after anaesthesia and surgery: Postoperative Quality of Recovery Scale (PQRS) I am the only Australian anaesthetist , and now Chair of an international board that developed and and validated a new scale, the Postoperative Quality of Recovery Scale (PQRS) to measure how well patients recover after anaesthesia. The first study, was published in Anesthesiology (2010), the most prestigious anaesthetic journal. This scale has been used as a research tool to compare different anaesthetic interventions, but is also being developed as a clinical quality tool. Being able to measure recovery will give anaesthetists important feedback on their practice, as well as being able to identify patients early after surgery who have not recovered well.. This work has great potential to engage The University of
  • 5. CV Colin Royse 5 Melbourne hospitals in collaborative research. PQRS is a simple tool to use and can be performed with minimal training. Quality of recovery is a new horizon in anaesthesia research and will interest the wider community. This is particularly important when engaging some of the hospitals where research is poorly developed. e. Cardiac surgery I am a co-investigator in cardiac surgery research. This includes long-term follow-up of patients who have had total arterial coronary bypass surgery, as well as measuring the effect of surgery on diastolic function. Teaching I am involved in both undergraduate and postgraduate education. I am also involved in registrar training in anaesthesia and pain management at The Royal Melbourne Hospital. Undergraduate: BBiomed, Medical and Dental students on anaesthesia-related subjects as required. I supervise students the MD scholarly selective and vocational selective programs. AMS/Honors I have supervised AMS students from the inception of the program. I have supervised 3 Science Honours students. Most students have achieved H2A/H1. Registrar training I train registrars in anaesthesia through my public hospital sessions. Research for higher degrees The table below shows the research students that have been/are under my supervision. All these students are anesthetists or critical care specialists. I believe that I am the only Victorian anaesthetist supervising PhD students who are clinicians Type: AMS = Advanced Medical Science; Hon = Science Honors; Mast = Masters, PhD = Doctorate of Philosophy; MD = Doctorate of Medicine; DPsych = Doctorate of Psychology. Supervisor: P = Primary supervisor; Co = Co-supervisor CoE = Co-supervisor for institution other than The University of Melbourne Year Name Type Supervisor Mark 2014 Jared Ou-Young Hon P In Progress 2014 Andrea Bowyer PhD P In Progress 2013 Alwyn Chuan PhD Co (McQuarie) In Progress 2012 Kavi Haji PhD P In progress 2011 John Faris PhD Co (UWA) In progress 2010 David Canty PhD Co (Utas) Completed 2009 Mohamed Ali MD Co (Uni Minah, Egypt) Withdrawn 2009 Darsim Harji PhD P Completed 2009 Emma Bourne Hon Co H2A 2007- Alicia Dennis PhD P Completd 2007 Andrew Huhn AMS P H2A 2006- Edward Hinch Mast Co Withdrawn 2006- David Andrews PhD P Completed 2006 Greg Chang AMS P H2A
  • 6. CV Colin Royse 6 2005- Graeme McLaren MD P On leave 2005- Paul Soeding PhD P Completed 2005- Kenneth Tung AMS P H1 2005- David Liew AMS P H2A 2005- Amanda Reid Mast Co H2A 2004 Jue Li Seah AMS P H2A 2003 Samuel Sha AMS P H1 2003- Kim Connelley PhD Co Completed 2002 Cheryl Remedios DPsych CoE Completed 2002 David Deelen AMS P H2A 2002 Ajay Bhratula AMS P H1 2002 Maal Roganathan AMS P H2B 2001 Christina Wong AMS P H1 2001 Randal Rohrlach Hon P P Distance based Echocardiography courses: The echocardiography education group, which I lead, is the main provider of echocardiography education to anaesthesia and critical care specialistsin Australia, and has gained a strong national and international reputation. The education program has facilitated the uptake of this technology into clinical practice, with a significant impact on patient management. Since 2004 the now discontinued PGDipEcho had nearly 460 graduates, with a few remaining to complete. By the end of Semester 2 2011, approximately 450 students had graduated from the new Certificate of Clinical Ultrasound, with 120 attaining the Diploma. By the end of 2013, approximately 2000 students had completed workshops, about 1100 of which had completed the limited transthoracic echocardiography course (HARTscan). Additionally about 500 delegates to conferences we have organised will have attended workshops. About 15-20% of distance education students are international enrolments. For reference, in Australasia, there are about 100 cardiothoracic surgeons, 250 cardiac anaesthetists, 750 cardiologists, 300 intensive care and 400 accident and emergency physicians. Overall we estimate that about 10% of all anaesthetists, more than 60% of all cardiac anaesthetists and 20% of intensive care physicians have completed or are undertaking our courses. a. Postgraduate Diploma of Perioperative and Critical Care Echocardiography (PGDipEcho). This course was developed following early use of transoesophageal echocardiography forcardiac surgery. I was one of the pioneers of this technique in Australia. The key aim was to set up a comprehensive education package to provide a diagnostic level knowledge base for practitioners, utilising distance education technologies to make learning easier. I led a steering committee and approximately 70 contributors from Australia and overseas. This course has become the leading means for anaesthesia and critical care specialists to learn echocardiography. The PGDipEcho has now been replaced with a series of nested courses, designed to cater better for the emerging non-cardiac anaesthesia craft groups. These include Postgraduate Certificate, Diploma, and Masters levels of education. b. Postgraduate Certificate of Clinical Ultrasound. All students start with this course, as it teaches basic assessment skills using echocardiography and surface
  • 7. CV Colin Royse 7 ultrasound. The knowledge base will enable practitioners to become “good basic sonographers” but without comprehensive diagnostic skills. This course is designed principally for those beginning echocardiography, or for the non- cardiac anaesthesia, emergency department, and intensive care specialties. Ultimately other modular certificates with focus on musculoskeletal or vascular sonography will be developed. c. Postgraduate Diploma of Clinical Ultrasound. Students complete another four subjects after the certificate course to obtain the diploma. The knowledge base is extended to now provide diagnostic level skills and to focus on transoesophageal echocardiography Our expectation is that approximately 50% of the certificate students will continue and complete the diploma. d. Masters of Clinical Ultrasound. This is now complete and released in 2014, approximately 50 students are currently enrolled. e. Hands-on Workshops. My echocardiography education group is also involved in running a number of hands-on workshops and seminars. This started as a means to provide hands-on experience for students who found it difficult to obtain at their local institution. However these programs have become self- standing, and have become important mechanisms for people wishing to start doing echocardiography and ultrasound guided nerve blocks. f. New developments. Our group has developed the Basic Perioperative TEE program for the National Board of echocardiography in the USA. We have currently enrolled 300 students. Another major development is to set up education courses incorporating echocardiography simulators. The first two courses in this series have been developed and tested in 2014. A new course called “Basic TTE” is under development. Collaborations a. Sonosite Corporation: Sonosite has facilitated our teaching programs in point-of- care ultrasound, and provided research equipment for our laboratory. b. Co-Director of the steering committee of the Postgraduate Diploma of Perioperative and Critical Care Echocardiography. The committee comprises 14 anaesthetists, intensive care physicians, or surgeons from across Australia and New Zealand, who served to guide the progress of the diploma course. c. Member of the international advisory board on the- postoperative quality of recovery scale (PQRS). This scale will act as a research endpoint to measure quality of recovery following anaesthesia and surgery. I am now the Chair of the PQRS scientific committee. d. Member of the advisory panel for the Australian and New Zealand College of Anaesthetists, and the Joint Faculty of Intensive Care Medicine, which formulate training guidelines for echocardiography and ultrasound use in anaesthesia and critical care medicine. e. Society of Cardiovascular Anesthesiology (SCA) collaboration: I have successfully formed a partnership with the SCA, which is the most respected organization in the USA concerning perioperative echocardiography. We are now running our distance courses under license from The University of Melbourne for the North American market. This has given us huge credibility outside of Australia in the field of echocardiography education.
  • 8. CV Colin Royse 8 Clinical development in anaesthesia My subspeciality interest is cardiac anaesthesia. I have been a pioneer in a number of developments in this field. In 1995, I received formal training in transoesophageal echocardiography and introduced it into the operating theatres at The Royal Melbourne Hospital. The technology is now embraced in cardiac surgery and its application has extended to other areas of anaesthesia. In the mid-1990s, I pioneered the use of fast track anaesthesia for cardiac surgery at the Royal Melbourne Hospital, including immediate extubation of patients in the operating theatre. Whilst my practice has become more conservative, aiming for early rather than immediate extubation, the process required many simultaneous changes in technique, including anaesthetic agents, temperature management and pain control. This work is recognised internationally, and I was invited to speak on it in 2008 at the International Congress of Cardiovascular Anaesthesia. I pioneered the use of epidural anaesthesia in cardiac surgery in Australia. This is an emerging trend in many other countries. My aim is to improve pain management for patients undergoing cardiac surgery. We have been performing the technique for over 15 years with good results, and without complication in over 2000 cases. I have published the world’s third largest clinical case series, and I am regarded as a world authority in the technique. I was invited to write the “Current Opinion” review of the topic in 2008. I wrote an editorial for Anesthesiology in 2011, and have lectured as a guest speaker on multiple occasions at international meetings. The focus of my clinical research now is the measurement of quality of recovery following anaesthesia and surgery. I am a member of an international panel which has developed and validated a new quality of recovery scale (PQRS – Postoperative Quality Recovery Scale). This will provide a measurement tool to identify quality of recovery beyond the normal clinical observation period (which for anaesthetists, is typically only a few hours). Studies investigating quality of recovery in cardiac surgery are currently undergoing ethics committee review. Administrative/Management I have set up and co-ordinate the “Postgraduate Diploma of Perioperative and Critical Care Echocardiography”.The course represents a collaboration of experts in echocardiography from Australia and New Zealand, and is administered through The University of Melbourne. I co-administer administer 7 full time and 6 part time research or admin staff. I set up the Anaesthesia and Pain Management Research Unit in 2006 within the Department of Pharmacology. This was designed to be an umbrella organization for anaesthetists to seek appointments with the university. The idea is to group anaesthetists into one unit, rather than the current state where they are dispersed by being attached to surgical or medical departments of their hospitals. It is critical for the development of anaesthesia as a discipline to group individuals of common interest, so that research, education, and publication output can be identified as belonging to the discipline of anaesthesia. I am the only continuing University employed academic in anaesthesia, critical care and emergency medicine. This indicates just how under resourced these specialties are. Numerically, the critical care and anaesthesia craft groups are in the top five specialties yet have almost no university representation. All other anaesthesia academics hold honorary
  • 9. CV Colin Royse 9 appointments. I have provided the co-ordination and mentoring for anaesthetists and other critical care specialists to help them to realize their academic goals. In 2010, I provided funding from the echocardiography programs for a 0.5 FTE position for an anaesthesia lecturer. I intend to increase this as funds allow. I served with the Australian Defence Force Reserves for 15 years, moving to inactive service in 1998. I held a range of appointments culminating in “Officer Commanding, Medical Company, 3BASB”. I participated in leadership courses and reached the rank of Substantive Major. The management responsibility of a company-sized unit is 100 personnel, and the organizational structure is similar to that of a department within a hospital. Professional memberships / Boards  Fellow of the Australian and New Zealand College of Anaesthetists  Member of the Australian Society of Anaesthetists  Member of the Australian Medical Association  Medical Registration No. MPG227116  AVANT Medical Defence Association No. 10278 Personal and leisure I enjoy music, skiing and travel. I still play the piano, though my practice time is ever diminishing with having teenage children. I am a real fan of classical music and opera. Publications Journal publications available in Pubmed 1. Callaway JK, Jones NC, RoyseAG, RoyseCF. Memory Impairment in Rats afterDesflurane Anesthesiais Ageand Dose Dependent. Journal of Alzheimer'sdisease : JAD. 2014. 2. Vegas A, Denault A, RoyseC. A bedsideclinical andultrasound-basedapproachto hemodynamic instability - Part II: bedside ultrasound in hemodynamic shock: Continuing Professional Development. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2014;61(11):1008-27. 3. Denault A, Vegas A, RoyseC. Bedsideclinical andultrasound-based approaches to the management of hemodynamic instability--part I: focus on the clinical approach: continuing professional development. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2014;61(9):843-64. 4. Haji DL, Ali MM, RoyseA, Canty DJ, Clarke S, RoyseCF. Interatrial septum motion but not Dopplerassessment predictselevated pulmonarycapillary wedgepressurein patientsundergoing cardiac surgery. Anesthesiology. 2014;121(4):719-29. 5. Bowyer A, Jakobsson J, Ljungqvist O, RoyseC. A review ofthescopeand measurement of postoperative quality ofrecovery. Anaesthesia. 2014;69(11):1266-78. 6. Canty DJ, Hayes JA, Story DA, Royse CF. Ultrasoundsimulator-assisted teaching of cardiac anatomy to preclinical anatomy students:A pilot randomized trial of athree-hourlearning exposure. Anatomical scienceseducation. 2014. 7. Liu J, Yuan W, Wang X, Royse CF, Gong M, Zhao Y, et al. Peripheral nerveblocks versus general anesthesiafor total kneereplacement in elderlypatients onthe postoperative quality of recovery. Clinical interventions in aging. 2014;9:341-50.
  • 10. CV Colin Royse 10 8. Royse CF, WilliamsZ, YeG, Wilkinson D, DeSteigerR, RichardsonM, et al. Kneesurgery recovery: Post-operative Quality of RecoveryScale comparison of ageandcomplexity ofsurgery. Acta anaesthesiologica Scandinavica. 2014;58(6):660-7. 9. Royse CF, WilliamsZ, PurserS, Newman S. Recovery afternasal surgery vs. tonsillectomy: discriminant validation of the Postoperative Quality ofRecoveryScale. Acta anaesthesiologica Scandinavica. 2014;58(3):345-51. 10. Newman S, Wilkinson DJ, RoyseCF.Assessment of early cognitive recovery aftersurgery using the Post-operative Quality of Recovery Scale. Acta anaesthesiologicaScandinavica. 2014;58(2):185-91. 11. Lindqvist M, RoyseC, Brattwall M, Warren-StombergM, Jakobsson J.Post-operative Quality of Recovery Scale:the impact of assessment methodon cognitive recovery. Acta anaesthesiologica Scandinavica. 2013;57(10):1308-12. 12. Royse CF, Newman S, Williams Z, Wilkinson DJ. A human volunteerstudy to identify variability in performancein thecognitivedomainofthepostoperativequality of recovery scale. Anesthesiology. 2013;119(3):576-81. 13. Soeding PF, Hoy S, HoyG, EvansM, RoyseCF. Effect ofphenylephrineonthe haemodynamic state andcerebral oxygen saturation duringanaesthesiain theupright position. British journal ofanaesthesia. 2013;111(2):229-34. 14. Griffiths JD, LeNV, Grant S, Bjorksten A, Hebbard P, Royse C. Symptomatic local anaesthetic toxicity and plasma ropivacaineconcentrationsaftertransversus abdominis planeblock for Caesarean section. British journal of anaesthesia. 2013;110(6):996-1000. 15. Haji DL, Royse A, RoyseCF. Review article: Clinical impact of non-cardiologist-performed transthoracic echocardiography in emergency medicine, intensivecaremedicine andanaesthesia. Emergency medicine Australasia: EMA. 2013;25(1):4-12. 16. Canty D, Royse C.A reply. Anaesthesia. 2013;68(2):207-8. 17. Udayasiri D, GangahanumaiahS, Royse C,RoyseA. Tricuspid valvepapillary muscle avulsion from a pulmonary artery catheter. ANZjournal of surgery. 2012;82(12):939-40. 18. Royse CF, CantyDJ, FarisJ, Haji DL, VeltmanM, Royse A.Corereview:physician-performed ultrasound: the time hascomeforroutine usein acute care medicine. Anesthesia andanalgesia. 2012;115(5):1007-28. 19. Canty DJ, RoyseCF, Kilpatrick D, BowyerA, Royse AG. The impact on cardiac diagnosis and mortality of focusedtransthoracic echocardiographyin hip fracturesurgery patients with increasedrisk ofcardiac disease: a retrospectivecohort study. Anaesthesia. 2012;67(11):1202-9. 20. Callaway JK, Jones NC, Royse AG, RoyseCF. Sevofluraneanesthesia does not impair acquisition learningormemory in the Morris water maze in youngadult andagedrats. Anesthesiology. 2012;117(5):1091-101. 21. Callaway JK, Jones NC, RoyseCF. Reply to: Isoflurane is not necessarily theonly cause of cognitive deficits. European journal ofanaesthesiology. 2013;30(1):43-4. 22. Royse CF, Chung F, NewmanS, Stygall J, WilkinsonDJ. Predictors ofpatient satisfaction with anaesthesia and surgery care: a cohort study usingthePostoperative Quality of Recovery Scale. European journal of anaesthesiology. 2013;30(3):106-10. 23. Faris JG, Hartley K, FullerCM, LangstonRB, RoyseCF, Veltman MG. Audit of cardiac pathologydetection usinga criteria-basedperioperativeechocardiography service. Anaesthesia and intensive care. 2012;40(4):702-9. 24. Lam K, Canty D, RoyseC, RoyseA. Hospital survey of point-of-carelungultrasounduse in the assessment ofperi-operativeandcritically ill patients. Critical care. 2012;16(3):437. 25. Dennis AT, Castro J, Carr C, Simmons S, Permezel M, Royse C. Haemodynamics in women with untreatedpre-eclampsia. Anaesthesia. 2012;67(10):1105-18. 26. Royse CF, Haji DL, FarisJG, Veltman MG, KumarA, Royse AG. Evaluationofthe interpretative skillsofparticipants of a limitedtransthoracicechocardiography training course (H.A.R.T.scan course). Anaesthesia and intensivecare. 2012;40(3):498-504.
  • 11. CV Colin Royse 11 27. Canty DJ, RoyseCF, Kilpatrick D, Williams DL, RoyseAG. The impact of pre-operative focusedtransthoracic echocardiographyin emergency non-cardiac surgery patientswith known or risk of cardiac disease. Anaesthesia.2012;67(7):714-20. 28. Canty DJ, RoyseCF, Kilpatrick D, Bowman L, RoyseAG. The impact of focusedtransthoracic echocardiographyin thepre-operativeclinic. Anaesthesia. 2012;67(6):618-25. 29. Callaway JK, Jones NC, RoyseCF. Isoflurane inducescognitivedeficits inthe Morris water maze task in rats. European journal of anaesthesiology. 2012;29(5):239-45. 30. Andrews DT, Sutherland J, Dawson P, Royse AG, Royse C. L-argininecardioplegia reduces oxidative stress and preservesdiastolic function in patients with low ejection fraction undergoing coronaryartery surgery. Anaesthesia andintensivecare. 2012;40(1):99-106. 31. Andrews DT, RoyseC, Royse AG. The mitochondrial permeability transition poreandits role in anaesthesia-triggeredcellularprotectionduringischaemia-reperfusioninjury. Anaesthesia and intensive care. 2012;40(1):46-70. 32. Ali MM, Royse AG, Connelly K, RoyseCF. The accuracy oftransoesophageal echocardiographyin estimatingpulmonary capillary wedge pressure in anaesthetisedpatients. Anaesthesia. 2012;67(2):122-31. 33. Soeding PF, Wang J, Hoy G, JarmanP, Phillips H, Marks P, et al. The effect ofthe sitting upright or'beachchair'position on cerebral bloodflow duringanaesthesiaforshoulder surgery. Anaesthesia and intensive care. 2011;39(3):440-8. 34. Brooks M, RoyseC, Eisen D, Sparks P, Bhagwat K, RoyseA. An accidental mass. Lancet. 2011;377(9779):1806. 35. Royse CF, Andrews DT, Newman SN, Stygall J, WilliamsZ, PangJ, et al. The influenceof propofol ordesflurane on postoperative cognitivedysfunction in patients undergoingcoronary artery bypass surgery. Anaesthesia.2011;66(6):455-64. 36. Faris JG, Veltman MG, RoyseC. Focusedtransthoracic echocardiography in the perioperative period. Anaesthesiaandintensivecare. 2011;39(2):306-7; author reply 7-8. 37. Royse CF, Ruizhi N, HuynhAL,RoyseAG. The Effect of a Hyperdynamic Circulation on Tissue DopplerValues: A Simulation in Young Adultsduring Exercise. Anesthesiology research and practice. 2011;2011:165874. 38. Connelly KA, Royse C, RoyseAG. Tissue DopplerEm andinstantaneous end-diastolic stiffness: validationagainst pressure-volumeloops in patients undergoingcoronary artery bypass surgery. Heart, lung& circulation. 2011;20(4):223-30. 39. Royse C. Epiduralsfor cardiac surgery: can wesubstantially reducesurgical morbidity or should we focus on quality of recovery? Anesthesiology. 2011;114(2):232-3. 40. Soeding PF, Crack PJ, Wright CE, Angus JA, RoyseCF. Levosimendanpreserves the contractile responsiveness ofhypoxic humanmyocardium viamitochondrial K(ATP)channel and potential pERK 1/2activation. Europeanjournal ofpharmacology. 2011;655(1-3):59-66. 41. Conaglen PJ, Ellims A, RoyseC, Royse A. Acuterepair oftraumatictricuspid valve regurgitationaided by three-dimensional echocardiography. Heart, lung& circulation. 2011;20(4):237-40. 42. Griffiths JD, Barron FA, Grant S, BjorkstenAR, HebbardP, Royse CF. Plasmaropivacaine concentrations after ultrasound-guidedtransversus abdominis planeblock. British journal of anaesthesia. 2010;105(6):853-6. 43. MacLaren G, KlugerR, Connelly KA, Royse CF. Comparativefeasibility of myocardial velocity and strain measurements using2 different methodswith transesophageal echocardiographyduringcardiac surgery. Journal of cardiothoracic andvascularanesthesia. 2011;25(2):216-20. 44. Royse CF, Newman S, Chung F, Stygall J, McKay RE, Boldt J, et al. Development and feasibility ofa scale to assesspostoperativerecovery: thepost-operativequality recovery scale. Anesthesiology. 2010;113(4):892-905.
  • 12. CV Colin Royse 12 45. Griffiths JD, Middle JV, BarronFA, Grant SJ, Popham PA, Royse CF. Transversus abdominis plane block does not provide additional benefit to multimodal analgesiain gynecological cancer surgery. Anesthesia and analgesia. 2010;111(3):797-801. 46. HebbardPD,RoyseCF. Lack of efficacywith transversus abdominis planeblock: isit the technique, theend points, or thestatistics?Regional anesthesia andpainmedicine. 2010;35(3):324. 47. Dennis A, Arhanghelschi I, Simmons S,RoyseC. Prospectiveobservational studyofserial cardiac output by transthoracic echocardiography in healthypregnant women undergoingelective caesarean delivery. International journal ofobstetric anesthesia. 2010;19(2):142-8. 48. BourneE, Wright C,RoyseC. A review oflocal anesthetic cardiotoxicity and treatment with lipid emulsion. Local and regional anesthesia. 2010;3:11-9. 49. Royse CF. Isa different dose ofanesthesia thereal problem?Anesthesia and analgesia. 2009;109(6):2031-2; authorreply 2. 50. Royse CF. Anaesthesia in septic patients: good preparationandmakingtheright choice? Critical care. 2009;13(6):1001. 51. Royse AG, RoyseCF. Epiaortic ultrasoundassessment ofthe aortain cardiac surgery. Best practice & researchClinical anaesthesiology. 2009;23(3):335-41. 52. Faris JG, Veltman MG, RoyseCF. Limited transthoracic echocardiography assessment in anaesthesia and critical care.Best practice & research Clinical anaesthesiology. 2009;23(3):285- 98. 53. Royse CF. Ultrasound-guided haemodynamic state assessment. Best practice& research Clinical anaesthesiology. 2009;23(3):273-83. 54. Royse CF. Ultrsasound in anaesthesiology andintensive care. Preface. Best practice & research Clinical anaesthesiology. 2009;23(3):vii. 55. Andrews DT, RoyseAG, RoyseCF. Functional comparison of anaesthetic agents during myocardial ischaemia-reperfusion usingpressure-volume loops. British journal of anaesthesia. 2009;103(5):654-64. 56. Royse CF. High thoracic epidural analgesia forcardiac surgery: time to movefrom morbidity to quality ofrecoveryindicators. Annalsofcardiac anaesthesia. 2009;12(2):168-9; author reply70-1. 57. Canty DJ, RoyseCF. Audit ofanaesthetist-performedechocardiography on perioperative management decisions fornon-cardiac surgery. British journal of anaesthesia. 2009;103(3):352-8. 58. Royse CF. High thoracic epidural anaesthesia forcardiac surgery. Current opinion in anaesthesiology. 2009;22(1):84-7. 59. Royse CF, BirdH, Royse AG. Routine assessment of coeliac axis andrenal artery flow is not feasible with transoesophageal echocardiography. Anaesthesia. 2009;64(1):103-4. 60. AlsaddiqueAA, RoyseAG, RoyseCF, Fouda MA. Management of diastolic heart failure following cardiac surgery. Europeanjournal of cardio-thoracic surgery : official journal of the European AssociationforCardio-thoracic Surgery. 2009;35(2):241-9. 61. HebbardP, Royse C. Audit of transverseabdominus plane block foranalgesia following caesarean section. Anaesthesia.2008;63(12):1382. 62. Royse C. Ultrasound education in anaesthesia:turningthe tables on convention. Annalsof cardiac anaesthesia. 2008;11(2):77-9. 63. Royse AG, Chang GS, NicholasDM, Royse CF. No lateulnarartery atheroma after radial artery harvest forcoronaryartery bypasssurgery. TheAnnalsofthoracic surgery. 2008;85(3):891-4. 64. Royse CF, Liew DF, Wright CE, Royse AG, AngusJA. Persistent depressionofcontractility and vasodilation with propofol but not with sevoflurane ordesflurane in rabbits. Anesthesiology. 2008;108(1):87-93. 65. Soeding PE, Royse CF, Wright CE,RoyseAG, AngusJA. Inoprotection: theperioperativerole of levosimendan. Anaesthesia and intensivecare. 2007;35(6):845-62.
  • 13. CV Colin Royse 13 66. HebbardP, Fujiwara Y,ShibataY, RoyseC. Ultrasound-guided transversusabdominisplane (TAP) block. Anaesthesia and intensive care. 2007;35(4):616-7. 67. Royse AG, RoyseCF. ICVTSon-linediscussion B Radial artery harvest preserves forearm blood flow. Interactivecardiovascular andthoracic surgery. 2007;6(5):602. 68. Royse A, RoyseC. A standardisedintraoperativeultrasoundexamination of theaorta and proximal coronary arteries. Interactive cardiovascularand thoracic surgery. 2006;5(6):701-4. 69. Royse CF, Soeding PF, Royse AG. Highthoracic epidural analgesiafor cardiac surgery: an audit of 874cases. Anaesthesiaandintensivecare. 2007;35(3):374-7. 70. Royse C. Is depthofanesthesia, as assessedby the bispectral index, related to postoperative cognitive dysfunction and recovery?Anesthesia and analgesia. 2007;104(5):1297; author reply -8. 71. HebbardP, Royse C. Ultrasoundguidedposteriorapproach to the infraclavicularbrachial plexus. Anaesthesia. 2007;62(5):539. 72. Royse CF, RoyseAG, RohrlachR, Wright CE, Angus JA. Thecardiovascular effectsof adrenaline, dobutamine andmilrinone in rabbitsusing pressure-volume loopsandguineapig isolated atrial tissue.Anaesthesia andintensivecare.2007;35(2):180-8. 73. Royse C, RemediosC, Royse A. High thoracic epidural analgesiareduces therisk oflong- term depressionin patientsundergoing coronary artery bypass surgery. Annalsofthoracicand cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons of Asia. 2007;13(1):32-5. 74. Royse CF, Connelly KA, MacLaren G, RoyseAG. Evaluation ofechocardiography indicesof systolic function: a comparativestudy usingpressure-volumeloops in patients undergoing coronaryartery bypasssurgery. Anaesthesia. 2007;62(2):109-16. 75. Royse CF, Seah JL, Donelan L, Royse AG. Point of care ultrasound forbasichaemodynamic assessment: novicecompared with an expert operator. Anaesthesia. 2006;61(9):849-55. 76. Maclaren G, KlugerR, Prior D, Royse A, RoyseC. Tissue Doppler, strain, andstrain rate echocardiography: principlesandpotential perioperativeapplications. Journal ofcardiothoracic and vascular anesthesia. 2006;20(4):583-93. 77. Royse CF, Hall J, RoyseAG. The 'mesentery' dressing for epidural catheterfixation. Anaesthesia. 2006;61(7):713. 78. Royse CE, ShaS, Soeding PF, Royse AG. Anatomical study ofthebrachial plexususing surface ultrasound. Anaesthesia andintensivecare. 2006;34(2):203-10. 79. Soeding PE, Sha S, RoyseCE, Marks P, Hoy G, RoyseAG. A randomizedtrial ofultrasound- guided brachial plexus anaesthesia in upperlimb surgery.Anaesthesia andintensivecare. 2005;33(6):719-25. 80. King G, FoleyJB, RoyseCF, Yastrebov K,Hussey M, BoyleG, et al. Myocardial stiffness and the timing difference betweentissue Dopplerimaging Ea andpeak mitral valveopeningcan distinguish physiological hypertrophy in athletes from hypertrophic cardiomyopathy. European journal of echocardiography: the journal of theWorkingGroup on Echocardiographyofthe European Society of Cardiology. 2006;7(6):423-9. 81. Royse CE, Royse AG, Deelen DA. Anaudit of morphine versusfentanyl as anadjunct to ropivacaine 0.2% forhigh thoracic epidural analgesia. Anaesthesiaandintensivecare. 2005;33(5):639-44. 82. Royse CF, RoyseAG. The myocardial andvasculareffects of bupivacaine, levobupivacaine, and ropivacaine usingpressurevolumeloops. Anesthesiaandanalgesia. 2005;101(3):679-87, table of contents. 83. ChakravarthyM, Nadiminti S, KrishnamurthyJ, Thimmannagowda P, Jawali V, Royse CF, et al. Temporary neurologic deficits in patients undergoing cardiac surgery with thoracic epidural supplementation. Journal of cardiothoracicandvascularanesthesia. 2004;18(4):512-20. 84. Royse CF, RoyseAG, BharatulaA, Lai J, Veltman M, Cope L, et al. Substernal epicardial echocardiography: a recommendedexamination sequenceandclinical evaluation in patients undergoingcardiac surgery. The Annals of thoracic surgery. 2004;78(2):613-9; discussion9.
  • 14. CV Colin Royse 14 85. Royse AG, RoyseCF, MaleskarA, Garg A. Harvest of the radial artery for coronaryartery surgerypreserves maximal bloodflow of theforearm. The Annals of thoracic surgery. 2004;78(2):539-42. 86. Royse AG, RoyseCF, WongCT. Graft flow increases with release of stabilizing devicein off- pump coronarysurgery. Annals of thoracic and cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascularSurgeonsofAsia. 2003;9(6):384-8. 87. Royse CF, RoyseAG, WongCT. Assessment of left ventricular functionduring off-pump coronaryartery bypasssurgery. Annalsof thoracic andcardiovascularsurgery : official journal of the AssociationofThoracic andCardiovascular Surgeons of Asia. 2003;9(6):371-7. 88. Royse CF, RoyseAG, Soeding PF, Mathieson EM. Descending aortic pulsed wave Doppler can predict changes in cardiacoutput duringoff-pumpcoronary arterybypass surgery.Annals of thoracic and cardiovascularsurgery : official journal of theAssociationofThoracic and CardiovascularSurgeons of Asia. 2003;9(5):314-8. 89. Blake DW, RoyseCF, Royse AG, Bjorksten AR, SoedingPF, PangJ. Alfentanil infusion asa component ofintravenous anaesthesia forcoronary arterybypass surgerywith "fast-track" recovery. Anaesthesia and intensive care. 2003;31(2):181-3. 90. Royse CF, RoyseAG, WongCT, Soeding PF. Theeffect ofpericardial restraint, atrial pacing, and increasedheart rate on left ventricularsystolicanddiastolic function in patients undergoing cardiac surgery. Anesthesia andanalgesia. 2003;96(5):1274-9, table of contents. 91. Royse C, RoyseA, SoedingP, Blake D, Pang J. Prospective randomized trial of high thoracic epidural analgesia forcoronary arterybypass surgery. The Annals of thoracic surgery. 2003;75(1):93-100. 92. Ho SC, Royse CF, Royse AG, PenberthyA, McRaeR. Persistent painaftercardiac surgery:an audit of highthoracic epidural and primaryopioidanalgesiatherapies. Anesthesia andanalgesia. 2002;95(4):820-3, table of contents. 93. Royse CF, RoyseAG, Soeding PF, Blake DW.Shapeandmovement of the interatrial septum predicts change in pulmonarycapillary wedgepressure. Annalsofthoracic andcardiovascular surgery: official journal ofthe Association of Thoracic and CardiovascularSurgeonsofAsia. 2001;7(2):79-83. 94. Royse C, Soeding P, RoyseA. Immediateorearly extubation:wheredo we start?Anesthesia and analgesia. 2001;92(4):1073-4. 95. Royse CF, RoyseAG. Afterload corrected fractional areachange(FACac):a simple, relatively load-independent measurement ofleft ventricular contractility in humans. Annalsof thoracic and cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons of Asia. 2000;6(5):345-50. 96. Purser S, RoyseCF, VelkovHA, Roberts LF. Topical application of ethanol to the tonsillar bed immediately following tonsillectomy does not improvepost-operativeanalgesia. The Journal of laryngology and otology. 2000;114(9):671-4. 97. Royse CF, RoyseAG, BlakeDW, GriggLE.Instantaneous end diastolicstiffness (IEDS): a simple, load independent measurement ofleft ventriculardiastolic function inpatients undergoing cardiac surgery. Annals of thoracic and cardiovascularsurgery : official journal of theAssociation of Thoracic and CardiovascularSurgeons of Asia. 2000;6(3):203-10. 98. Royse AG, RoyseCF, Ajani AE, Symes E, Maruff P, Karagiannis S, et al. Reduced neuropsychological dysfunction usingepiaortic echocardiography and theexclusiveY graft. The Annals of thoracic surgery. 2000;69(5):1431-8. 99. Royse CF, Barrington MJ, Royse AG. Transesophageal echocardiography values forleft ventricularend-diastolic area and pulmonary veinandmitral inflow Dopplervelocitiesin patients undergoingcoronary artery bypassgraft surgery. Journal ofcardiothoracic and vascular anesthesia. 2000;14(2):130-2.
  • 15. CV Colin Royse 15 100. Royse AG, RoyseCF, Tatoulis J, Grigg LE, ShahP, Hunt D, et al. Postoperativeradial artery angiography forcoronary arterybypass surgery.European journal of cardio-thoracic surgery : official journal of the European Associationfor Cardio-thoracic Surgery. 2000;17(3):294-304. 101. Macguire B,RoyseC, Royse A, DuaneM, PangJ. Lungfunction followingcardiac surgeryis not affected by postoperativeventilation time. Annals of thoracic and cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons ofAsia. 2000;6(1):13-8. 102. Royse CF, RoyseAG, BlakeDW, GriggLE.Measurement ofcardiac output by transoesophageal echocardiography: a comparisonoftwo Dopplermethods with thermodilution. Anaesthesia and intensive care. 1999;27(6):586-90. 103. Royse AG, RoyseCF, Tatoulis J. Total arterial coronary revascularization and factors influencing in-hospital mortality. Europeanjournal ofcardio-thoracic surgery : official journal of the EuropeanAssociation for Cardio-thoracic Surgery. 1999;16(5):499-505. 104. Royse AG, RoyseCF, GrovesKL, BusB, YuG. Bloodflow in compositearterial graftsand effect of nativecoronary flow. TheAnnalsofthoracicsurgery. 1999;68(5):1619-22. 105. Royse AG, RoyseCF, Raman JS. Exclusive Y graft operation formultivessel coronary revascularization. TheAnnalsofthoracic surgery. 1999;68(5):1612-8. 106. Royse CF, RoyseAG, Soeding PF. Routine immediateextubation after cardiacoperation: a review of ourfirst 100 patients. TheAnnalsofthoracic surgery. 1999;68(4):1326-9. 107. Royse CF, RoyseAG, BlakeD, Grigg LE. Aortic valve area: measurement by transesophageal echocardiographyandprediction byleft ventricularoutflow tract area. Annals ofthoracic and cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons of Asia. 1999;5(3):168-73. 108. Royse AG, RoyseCF, Shah P, Williams A, Kaushik S, Tatoulis J. Radial artery harvest technique, use andfunctional outcome. European journal of cardio-thoracicsurgery : official journal of theEuropeanAssociation for Cardio-thoracic Surgery. 1999;15(2):186-93. 109. Royse C, RoyseA, Blake D, GriggL.Screeningthethoracic aortafor atheroma: a comparison of manual palpation, transesophageal andepiaortic ultrasonography. Annals of thoracic and cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascular Surgeons of Asia. 1998;4(6):347-50. 110. Royse C, RoyseA, Blake D, GriggL.Assessment of thoracic aortic atheroma by echocardiography: a new classification andestimationofrisk ofdislodgingatheroma during three surgical techniques. Annals of thoracic and cardiovascularsurgery : official journal of the AssociationofThoracicandCardiovascularSurgeonsofAsia. 1998;4(2):72-7. 111. Royse CF, Tiernan RJ, Portelli SM, DaviesS, ArblasterR, Bjorksten AR, et al. Theeffect of supplemental oxygenonthe incidenceofhypoxaemiaafterpremedication in patients undergoing cardiac surgery. Anaesthesia and intensive care. 1997;25(4):347-9. 112. Dawson PJ, Libreri FC, JonesDJ, Libreri G, Bjorkstein AR, RoyseCF. Theefficacy of adding a continuous intravenous morphine infusion to patient-controlledanalgesia (PCA) in abdominal surgery. Anaesthesiaand intensivecare. 1995;23(4):453-8. 113. HebbardGS,RoyseCF, Bjorksten AR.Oxygen supplementation during upper gastrointestinal endoscopy: a comparisonoftwo methods. Endoscopy. 1994;26(3):278-82.
  • 16. CV Colin Royse 16 Grants and other teaching/research income The table below lists grants received. Type of grant: CG = national competitive grant; IG = industry grant; T = teaching income %CR = % of the grant designated for me for competitive grants. Education income is shared between myself and my laboratory co-director (Alistair Royse-AR). Org is the organization or funding body. [CR-PI] indicates where I am the principal investigator for the particular project. Year s Title Org Type Amount $ %CR 2014 NHMRC NHMRC CG $709,000 10% (CIE) 2014 NIH Trajectory of Recovery in the Elderly (TORIE) NIH 1R01AG046634-01A1 NIH CG 1,000,000 5% (consultant) 2012 NMHRC grant (CIB) - The impact of anaesthesia and inflammation of cognition NRMRC CG 280,000 40% (CIB) 2011 ANZCA Academic Enhancement Grant: The impact of anaesthesia and inflammation of cognition ANZCA CG 90,000 100 (CIA) 2010 When is anaesthesia detrimental and when is it protective NHF CG 124,000 50% (CIA) 2009 Quality of recovery following knee surgery Baxter IG 189,000 100% (CR-PI) 2007 Validation of Tissue Doppler Strain against pressure volume loops in Pigs ANZCA CG 48,000 70% 2007 A randomized trial of propofol versus desflurane on the development of cognitive decline following CABG Baxter IG 400,000 CR-PI (70%) 2007 Investigation of the cardiovascular effects of anaesthetics using pressure volume loops Baxter IG 80,000 CR-PI (70%) 2005 The effects of bleeding on economic cost and morbidity in patients undergoing cardiac surgery NovoN ordisk IG 50,000 CR-PI (60%) 2004 Evaluation of the Sonosite Titan portable ultrasound machine Sono- site IG 20,000 [CR-PI] (70%) 2003 Evaluation of echocardiography indices of left ventricular function using pressure volume loops CVL CG 25,000 50% 2003 Evaluation of levosimendan using ASA CG 40,000 80%
  • 17. CV Colin Royse 17 pressure volume loops 2003 Comparison of the cardiotoxic effects of bupivacaine levobupivacaine and ropivacaine in a rabbit model using pressure volume loops CASS CG 25,000 80% 2003 - 2004 A randomised trial of cardiopulmonary bypass for coronary artery surgery NHF CG 99,000 50% 2002 Comparison of the cardiotoxic effects of bupivacaine levobupivacaine and ropivacaine in a rabbit model using pressure volume loops Astra Zeneca IG 20,000 [CR-PI] (70%) 2002 Evaluation of left ventricular function and graft flows during of pump coronary artery surgery Edward Dunlop CG 15,000 [AR-PI] (30%) 2002 Estimation of LVEDP using transoesophageal echocardiography ASA CG 10,000 70% 2001 Epidural use in cardiac surgery Astra zeneca IG 10,000 [CR-PI] (80%) 2001 Validation of simple indices of left ventricular function using echocardiography Winder -mere CG 10,000 80% 2001 Validation of simple indices of left ventricular function using echocardiography Perpert Found CG 10,000 80% 2001 Validation of simple indices of left ventricular function using echocardiography ASA CG 10,000 80% 2001 Equipment grant to purchase CFL 512 cardiac function analyser to perform pressure volume loops UoM CG 55,000 80% 2001 Equipment grant to purchase CFL 512 cardiac function analyser Ramma -cciotti CG 25,000 80% 2001 Equipment grant to purchase CFL 512 cardiac function analyser Med- tronic IG 10,000 [CR-PI] (60%) 2001 Equipment grant to purchase CFL 512 cardiac function analyser AMC IG 5,000 [CR-PI] (50%) 2000 - 2001 A randomised trial of epidural use in cardiac surgery NHF CG 99,000 [CR-PI] 70% 2000 A randomised trial of epidural use in cardiac surgery ASA CG 10,000 70% 2000 A randomised trial of epidural use in cardiac surgery Astra Zeneca IG 10,000 [CR-PI] (70%) 1998 - 1999 Postgraduate research scholarship NHMRC CG 48,000 100%
  • 18. CV Colin Royse 18 National and international presentations. I deliver national or international presentations > 5 time per year, with the majority ion recent years being international presentations as an invited speaker. Presentations for the last 3 years are shown below: 1. National. Invited speaker: Postoperative Quality of Recovery - are we doing a good job? ANZCA, ASM; Perth, Australia 2012. 2. National. Invited speaker: Utility of rapid scanning (goal focused) echocardiography. ANZCA ASM; Perth Austalia 2012. 3. International. Invited speaker: Horses for courses: different inotropes for different disease states. Cardiothoracic & Intensive Care Symposium; Argentina 2012. 4. International. Invited speaker: Basic haemodynamic state assessment. World Congress of Anesthesiology; Argentina 2012. 5. International. Invited speaker: CVC-PA versus echo: Pro-con debate. World Congress of Anesthesiology; Argentina 2012. 6. International. Postoperative quality of recovery: Data presentaiton from studies using the PQRS. World Congress of Anaesthesiology; Argentina 2012. 7. International. Basic TEE assessment of the Mitral Valve. American Society of Anesthesiology; Chicago, USA 2012. 8. International. Keynote speaker: Postoperative Quality of Recovery: the new horizon for anaestheia. 2011 International Basic and Clinical Research Forum of Anesthesia; Xian, China 2012. 9. International. Invited speaker: Postoperative quality of recovery: are we doing a good job. European Society of Anaesthesia; Paris, France 2012. 10. International. Invited speaker: Echo to the rescue. International Congress of Cardiothoracic and Vascular Anesthesia (ICCVA); Auckland, NZ 2012. 11. National. Invited speaker: Transthoracic Echocardiography in non-cardiac surgery. The ULTRA Meeting - ANZCA; Melbourne, Australia 2012. 12. National. Keynote speaker: Ultrasound for everyone - how ultrasound is changing clinical practice. ANZCA ASM; Melbourne, Aust 2013. 13. National. Keynote speaker: The limitations of Evidence based medicine. ANZCA ASM; Melbourne, Aust 2013. 14. National. Keynote speaker: Measureing quality of recovery. ANZCA ASM; Melbourne, Australia 2013. 15. International. Invited speaker: Rescue TEE. American Society of Anesthesiology; Sann Francisco, USA 2013. 16. International. Invited Speaker: Focused Cardiac Ultrasound. 10th Meeting of Asian Society of Cardiothoracic Anesthesiologists; Singapore 2013. 17. International. Invited Speaker: Postoperative cognitive dysfunction and effects on the developing brain. European Society of Anaesthesiology; Madrid, Spain 2013. 18. International. Keynote speaker: Postoperative Quality of Recovery: The new horizon in Anaesthesia practice. Annual Scientific Meeting in Anaesthesiology (Hong Kong Society of Anaesthesia); Hong Kong 2013. 19. International. Keynote speaker: Ultrasound for everyone - the new horizon for anaestehsia practice. Annual Scientific Meeting in Anaesthesiology (Hong Kong Society of Anaesthesia) 2013. 20. International. Keynote speaker: Ultrasound para todos - how ultrasound is changing clincal practice. Congreso Chileno de Anesthsiologica; Chile 2013.
  • 19. CV Colin Royse 19 21. International. Keynote speaker: Postoperative Quality of Recovery scale: Hacia un Nuevo Score de Alta Post Anestesia. Congreso Chileno de Anesthsiologica; Chile 2013. 22. International. Invited speaker: Should basic TEE be in the core curriculum of anesthesiology residency training? American Society of Anesthesiology; New Orleans, USA 2014. 23. International. Keynote speaker: Ultrasound for everyone –the new horizon for anesthesia and critical care practice. The 5th Visual Technology Medical Conference in Anaesthesia/Pain/Critical Care/Emergency; China 2014. 24. International. Grand Round: Postoperative Quality of Recovery: The new horizon in anaesthesia practice. Grand Round; Mt Sanai, New York, USA 2014. 25. International. Keynote speaker: Ultrasound for everyone –the new horizon for clinical ultrasound. 14th Annual Scientific Session of Chinese Society of Ultrasound in Medicine Suzhou, China 2014. 26. International. Invited speaker: Ultrasound for everyone –the new horizon for anesthesia and critical care practice. Chinese Society of Anesthesiology annual scientific meeting; Chengdu, China 2014. 27. International. Keynote speaker: Estimating ventricular volume. 11th Annual International Symposium on Ultrasound and Regional Anesthesia 2014; Toronto, Canada 2014. 28. International. Keynote speaker: Perioperative TTE applications in anesthesia and critical care practice. 11th Annual International Symposium on Ultrasound and Regional Anesthesia 2014; Toronto, Canada 2014. 29. International. Invited Speaker: Outcomes for the Anaesthetist. Enhanced Recovery After Surgery; Valencia, Spain 2014.