MFC16-Agenda

20-21 October, 2016, London, UK
www.globalengage.co.uk/microfluidics.html #GEMFC16
2nd Microfluidics Congress
UTILISING MICROFLUIDIC TECHNOLOGIES AS A TOOL FOR PROGRESSING MEDICAL RESEARCH
AND PATIENT CARE
Building on the success of our 2015 Microfluidics Congress in London, Global Engage is pleased to announce the 2nd Microfluidics Congress,
which will be held on 20-21 October in London, UK at the Novotel London West. The event will be co-located with the 4th qPCR & Digital
PCR Congress, and the 3rd Synthetic Biology Congress. Last year’s combined events attracted over 550 attendees and more than 100 poster
presentations.
Microfluidics is a rapidly developing area of research, and scientists are continually discovering the wide range of possibilities the technology
can provide. At the intersection of engineering, physics, chemistry, nanotechnology and biotechnology, microfluidics is revolutionising the way
patients are diagnosed, monitored and treated, and is unlocking the potential for reduced reagent consumption and thus, cost.
Attracting experts working in all areas of microfluidics, the conference will examine the latest developments in the technologies and techniques
being used for progressing medical research, as well as the challenges and future of microfluidics. Should you be an expert in developing
microfluidics technologies, or a scientist using microfluidics to further medical research, the conference will be an excellent opportunity to learn,
share, discuss and engage with the most current microfluidics research and technology. During the two-day conference, there will be networking
breaks to promote interaction with your peers, expert led case study presentations, and a dynamic exhibition room filled with technology
providers showcasing their technologies and solutions.
Confirmed Speakers Include:
Andreas Manz
KIST Europe,
Saarbrucken
Germany
Eugenia
Kumacheva
University Professor,
Department of
Chemistry, University
of Toronto, Canada
J. Michael Ramsey
Minnie N. Goldby
Distinguished Professor of
Chemistry, University of
North Carolina at Chapel
Hill, USA
Christoph Merten
Principal Investigator /
Group Leader
Microfluidics, Genome
Biology Unit, European
Molecular Biology
Laboratory, Germany
Conference Synopsis
Strategy and Technology in Microfluidics
 Commercialisation of microfluidic
technology
 Droplet microfluidics
 Digital microfluidics
 Centrifugal microfluidics
 Dielectrophoresis
 Paper-based systems
 Optofluidics
 Inertial microfluidics
 Acoustofluidics
 Electrokinetics
 Gas microflows
 Sensing technologies
 Modelling and simulation
 Microfabrication
 Sample preparation
 3-D printing of microfluidic devices
Case Studies and Applications in Medical Research
 Point-of-care diagnostics and disease monitoring
 Isolating and analysis of circulating tumour cells (CTCs)
 Single cell analysis
 Synthetic biology
 Lab-on-a-chip
 Organ-on-a-chip
 DNA analysis
 Biomaterials and tissue engineering
 Biomarker analysis
 Proteomics
 Cell sorting
 High throughput screening

Confirmed Speakers
Andreas Manz
KIST Europe, Saarbrucken
Germany
Piotr Garstecki
Professor, Group Leader,
Institute of Physical Chemistry,
Polish Academy of Sciences,
Poland
Jörg P. Kutter
Professor, Analytical Biosciences,
Department of Pharmacy,
University of Copenhagen,
Denmark
Anja Boisen
Professor, Department of Micro-
and Nanotechnology, Technical
University of Denmark
Jenny Tillotson
Founder of eScent; Visiting
Scholar, University of
Cambridge, UK
Charles Baroud
Associate Professor, École
Polytechnique; Unit Head, Institut
Pasteur, Paris, France
Takehiko Kitamori
Professor, Department of
Bioengineering, The University of
Tokyo, Japan
Emmanuel Delamarche
Research Staff Member, IBM
Research - Zurich, Switzerland
Alberto Escarpa
Professor of Analytical Chemistry,
Director of the Department of
Analytical Chemistry, Physical
Chemistry and Chemical
Engineering and Head of Doctorate
Program of Fine Chemistry,
University of Alcala, Spain
Eugenia Kumacheva
University Professor, Department of
Chemistry, University of Toronto,
Canada
Joshua Edel
Reader in (Bio)Sensing and
Analytical Sciences, Department of
Chemistry, Imperial College
London, UK
Oliver Schmidt
Professor, Director, Institute for
Integrative Nanosciences, IFW
Dresden, Germany
Jenny Emnéus
Professor, Department of Micro-
and Nanotechnology, Technical
University of Denmark
Jean-Christophe Baret
Full Professor, University of
Bordeaux; Team Leader, CNRS,
France
Jonathan Cooper
Wolfson Chair of Bioengineering,
EPSRC Fellow, ERC Advanced
Investigator, University of Glasgow,
UK
Thomas Laurell
Professor Medical Chemical
Microsensors, Department of
Biomedical Engineering, Lund
University, Sweden
Christoph Merten
Principal Investigator / Group
Leader Microfluidics, Genome
Biology Unit, European Molecular
Biology Laboratory, Germany
Arben Merkoçi
ICREA Professor, Director of the
Nanobioelectronics & Biosensors
Group, Catalan Institute of
Nanoscience and Nanotechnology
(ICN2) & BIST, Barcelona, Spain
Gillian M. Greenway
Professor of Analytical Chemistry,
Department of Chemistry,
University of Hull, UK
Thomas Franke
Professor in Biomedical
Engineering, Chair in Biomedical
Engineering, University of Glasgow,
UK
J. Michael Ramsey
Minnie N. Goldby Distinguished
Professor of Chemistry, University
of North Carolina at Chapel Hill,
USA
2nd Microfluidics Congress – 20-21 October, 2016, London, UK
The 2nd Microfluidics Congress is co-located with the:
4th qPCR and Digital PCR Congress
Bringing together over 175 industry and academic experts working in areas such as molecular biology/diagnostics, gene expression, genomics,
biomarkers, pathogen detection, GMO, mRNA, NGS, bioinformatics and data management, the congress will examine the latest developments,
opportunities and applications of both dPCR and qPCR through case studies across diverse areas such as oncology, infectious diseases, vaccines,
prenatal diagnostics, clinical applications, microbiology, food microbiology, environmental testing and other novel applications.
http://www.globalengage.co.uk/qpcr.html
3rd Synthetic Biology Congress
Designed for experts working in genome engineering, technological developments, protein design, cell building, bio-manufacturing and gene
editing, the Synthetic Biology Congress will examine the latest developments in these fields in both the healthcare and plant biology sectors. New
to the conference in 2015 was a third stream focusing on Investment, Start-Ups, Strategy and Bioethics, for those looking for investment
opportunities and seeking to further exploit their research.
http://www.globalengage.co.uk/synthetic-biology.html

Platinum Sponsors
Gold and Silver Sponsors
Supporting Sponsors
2nd Microfluidics Congress, 4th qPCR & Digital PCR Congress, 3rd Synthetic Biology Congress
SPONSORS

8:00-8:50 Registration & Coffee
8:50-9:00 Chair’s Opening Remarks:
9:00-9:35 Keynote Address:
Microfluidics, channel networks and self assembly
Microfluidic chips are usually defined by photolithography masks which are generated from straight lines and CAD programs. The
manufacturing process usually gets more complex if multiple depths, i.e. multiple masks have to be used, and variations in depth profile are
difficult to achieve. We will present a simple way of obtaining channel structures which feature gradually increasing or decreasing channel
depths, and which also can feature irregularities in its surface. At first sight, this may seem inappropriate, may look “ugly” and not engineering-
like. However, in biological surroundings, we can see such structures, and they are fully functional.
Plant leaves are used as templates for channel patterns, including its fine structure and including its macroscopic network pattern. Structures are
formed in PDMS and covered by glass slides for microscopic observation. Structures are used for investigating capillary pumping and cell
behaviour.
Confirmed:
Andreas Manz, KIST Europe, Saarbrucken Germany
9:35-10:00 Creating Unique Flows and Functions in Microfluidics by Shaping Acoustic Forces with Phononics
1. Advanced microfluidic manipulations using acoustics
2. Low cost disposable platforms
3. Applications in drug delivery, molecular diagnostics, cell separations and NGS
Confirmed:
Jon Cooper, Wolfson Chair of Bioengineering, EPSRC Fellow, ERC Advanced Investigator, University of Glasgow, UK
10:00-10:30
Solution Provider Presentation:
For sponsorship opportunities, please contact Nick Best / Gavin Hambrook at sponsorship@globalengage.co.uk
10:30-11:40 Morning Refreshments
Even Numbered Poster Presentation Sessions
One-to-One Partnering Meetings
11:40-12:05 Acoustic nanoparticle trapping and enrichment enables a rapid route to biomarker analysis in extracellular vesicles
Confirmed:
Thomas Laurell, Professor Medical Chemical Microsensors, Department of Biomedical Engineering, Lund University, Sweden
12:05-12:30 Title: to be confirmed
Topic: Acoustofluidics
Confirmed:
Thomas Franke, Professor in Biomedical Engineering, Chair in Biomedical Engineering, University of Glasgow, UK
12:30-13:00
13:00-14:00 Lunch
Afternoon chair:
Topic: Controlling molecular transport in minimal emulsions
Confirmed:
Jean-Christophe Baret, Full Professor, University of Bordeaux; Team Leader, CNRS, France
14:25-14:50 Microdroplet technologies for high-throughput experimentation in biology and for the point-of-care
 Droplet microfluidic systems allow to encapsulate and isolate chemical and biological processes inside the pico- to -micro-liter
droplets.
 One interesting avenue of recent development is in building automated systems that generate and manipulate microscopic droplet
reactors over extended periods of time. These systems can be used to e.g. study the evolution in hundreds of independent cultures of
microorganisms over extended periods of time providing fascinating new tools for the research on emergence of drug resistance in
fluctuating chemical environments.
 The physics of flow at small scale can also be used to construct systems that execute complicated protocols on multiple microdroplets
completely passively, with minimum requirement for precision in handling, opening these systems for use in point-of-care settings and
simplifying common laboratory protocols.
Confirmed:
Piotr Garstecki, Professor, Group Leader, Institute of Physical Chemistry, Polish Academy of Sciences, Poland
Agenda: Day One – Thursday 20th October, 2016
For more information please contact Steve Hambrook, Conference Director, Global Engage Ltd.
steve@globalengage.co.uk +44 (0) 1865 849841

Confirmed:
Takehiko Kitamori, Professor, Department of Bioengineering, The University of Tokyo, Japan
15:15-15:45
15:45-16:35 Afternoon Refreshments
Odd Numbered Poster Presentation Sessions
16:35-17:00 Labs-on-a-chip meets smart nanomaterials and micromotors
Micro and nanomotors represent one of the most exciting horizons in micro and nanotechnologies at the vanguard of Analytical Chemistry. Such
“nanoscale tools” offer considerable promise for advanced sensing, bio sensing and labs-on-a-chip (LOCs) applications.
In this talk, selected examples illustrating the analytical potency of Janus micromotors and the coupling of quantum dots-based tubular
micromotors will be discussed.
Relevant examples involving graphene-based LOCs and graphene-based tubular micromotors, which combine the outstanding catalytic
properties of micromachines with the unique surface chemistry of graphene, will be also discussed.
Self-propelled antibody-functionalized synthetic catalytic microengines for capturing and transporting target proteins well as biological motors
in LOCs devices will finally be illustrated.
Confirmed:
Alberto Escarpa, Professor of Analytical Chemistry, and Director of the Department of Analytical Chemistry, Physical Chemistry and
Chemical Engineering and Head of Doctorate Program of Fine Chemistry, University of Alcala, Spain
17:00-17:25 Microtubular MEMS for microfluidic applications
Microtubular MEMS are designed and constructed on chip by self-rolling differentially strained nanomembrane materials into fully functional
and integrative microtubular architectures. This makes them attractive for a broad range of applications and scientific research fields ranging
from novel hybrid heterostructure devices to compact 3D systems both on and off the chip. Microtubular MEMS are exploited to construct ultra-
compact and ultra-sensitive advanced electronic circuitry, sensors and optofluidic components around fluidic channels towards the
implementation of a lab-in-a-tube system. They are also useful to study basic mechanisms of single cancer and stem cell migration, growth and
mitosis in realistic 3D confined environments. Off-chip applications include biomimetic microelectronics for regenerative cuff implants and the
development of hybrid microbiorobotic motors for paradigm shifting reproduction technologies.
Confirmed:
Oliver Schmidt, Professor, Director, Institute for Integrative Nanosciences, IFW Dresden, Germany
17:25-17:50 A comparison of detection approaches for selective and sensitive biosensing in microfluidic devices
 Immunoassays with chemluminescence detection with reproducible electrochemical immobilisation for hormones
 Label free optical biosensing using dye doped leaky waveguides with aptamers
Confirmed:
Gillian M. Greenway, Professor of Analytical Chemistry, Department of Chemistry, University of Hull, UK
17:50-18:15 Paper-based biosensors for diagnostics
 Microfluidics is quite compatible with paper-based platforms for biosensing technologies
 A variety of optical and electrical detection technologies can be easily integrated and properly works onto paper
 Paper-based platforms can be used as cost-efficient devices for diagnostics beside safety & security and other applications
Confirmed:
Arben Merkoçi, ICREA Professor, Director of the Nanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and
Nanotechnology (ICN2) & BIST, Barcelona, Spain
18:15 Chair’s Closing Remarks and End of Day 1
18:15-19:15 Networking Drinks Reception
Agenda: Day One continued – Thursday 20th October, 2016

8:00-8:35 Coffee and Networking Meetings
8:35-8:40 Chair’s Welcome Address:
8:40-9:15 Keynote Address:
Title: to be confirmed
Topic: POC diagnostics
Confirmed:
J. Michael Ramsey, Minnie N. Goldby Distinguished Professor of Chemistry, University of North Carolina at Chapel Hill, USA
9:15-9:40 Microfluidics and carbon dioxide
Confirmed:
Eugenia Kumacheva, University Professor, Department of Chemistry, University of Toronto, Canada
9:40-10:10
10:10-11:20 Morning Refreshments
Odd Numbered Poster Presentation Sessions
11:20-11:45 Thiolene-based microfluidic devices as versatile tools for pharmaceutical applications
 Fabrication aspects using rheology-modified thiolene resins in a roll-to-plate approach
 Thiolene-based enzyme micro-reactors for drug metabolite screening
 Thiolene-based enzyme micro-reactors for peptide-mapping of protein-based drugs
Confirmed:
Jörg P. Kutter, Professor, Analytical Biosciecnes, Department of Pharmacy, University of Copenhagen, Denmark
11:45-12:10 Microfluidic electrochemical arrays for biosensing applications
2D/3D perfusion and sensor systems, 3D scaffolds, organ-on-a-chip systems
Confirmed:
Jenny Emnéus, Professor, Department of Micro- and Nanotechnology, Technical University of Denmark
12:10-12:35 Spatially controlled 3D and 2D cultures towards organs on a chip
 We use our recently developed microfluidic device to implement 3D cell cultures at spatially defined locations.
 This allows in-situ cytometry at the population, spheroid, and cell scales.
 By combining the 3D cultures with 2D culture, we can explore interactions between different cell types, towards functional organ-
on-a-chip devices.
Confirmed:
Charles Baroud, Associate Professor, École Polytechnique; Unit Head, Institut Pasteur, Paris, France
12:35-13:05
13:05-14:05 Lunch
Afternoon Chair:
14:05-14:30 Precision Diagnostics based on modular capillary-driven elements
One of our contributions to the field of microfluidics is the development of capillary-driven microfluidic chips for highly miniaturized
immunoassays. In this presentation, I will review how to program capillary flow and encode specific functions to form microfluidic elements
that can easily be assembled into self-powered devices for immunoassays. I will also present how small peripherals can augment the
functionality of microfluidic chips that have integrated electrodes for example for monitoring flow with sub-nanoliter precision and for
providing connectivity to smartphones. All together, capillary-driven elements can bring extremely high control for manipulating sub-microliter
volumes of samples and picogram quantities of reagents and may therefore extend the performances of microfluidic devices for point-of-
care diagnostics to a next level of precision.
Confirmed:
Emmanuel Delamarche, Research Staff Member, IBM Research - Zurich, Switzerland
14:30-14:55 Living droplets – phenotypic and genotypic single-cell screens for antibody discovery and biomedical research
We have developed fully integrated droplet-based microfluidic platforms for the screening of therapeutic antibodies. In these systems tiny
aqueous droplets (picoliter volumes) surrounded by oil serve as independent assay vessels. The technology allows the direct screening of >1
million primary, non-immortalized plasma cells for the secretion of antibodies that do not just bind to a drug target, but functionally inhibit it.
Recently, we have adapted this approach for the use of human plasma cells and furthermore developed multi-colour readout procedures. In
parallel to these phenotypic assays, we have also established single-cell genotype assays, e.g. to identify disease relevant species in the
human gut microbiome.
Confirmed:
Christoph Merten, Principal Investigator / Group Leader Microfluidics, Genome Biology Unit, European Molecular Biology Laboratory,
Germany
Agenda: Day Two – Friday 21st October, 2016

14:55-15:20 Micro and nano structures for oral drug delivery and sensing
Micrometer sized containers can be used for oral drug delivery. The containers will protect active pharmaceutical ingredients during the
passage through the stomach and facilitate adhesion to the wall of the intestine for controlled and unidirectional release, followed by
absorption through the intestine. We will show our recent findings and results in the areas of; microfabrication of containers in a simple and
rapid manner, loading of drugs, pH sensitive lids and in vitro/in vivo testing.
Using the optics and/or mechanics from a DVD player compact and sensitive sensor systems can be realized. By rotating a disc with
integrated microfluidic channels it is possible to manipulate liquid samples such as blood – performing crucial operations like separation,
valving and mixing. We integrate sensors such as cantilevers, SERS substrates, nanoparticles, electrodes and resonating strings with
centrifugal microfluidics. Examples of applications include rapid diagnostics, prognostics, food analysis and studies of thermal properties and
degradation of polymers.
Confirmed:
Anja Boisen, Professor, Department of Micro- and Nanotechnology, Technical University of Denmark
15:20-15:50 Afternoon Refreshments
Even Numbered Poster Presentation Sessions
15:50-16:15 Novel Strategies in Single Molecule Sensing
Analytical Sensors plays a crucial role in today’s highly demanding exploration and development of new detection strategies. Whether it be
medicine, biochemistry, bioengineering, or analytical chemistry the goals are essentially the same: 1) improve sensitivity, 2) maximize
throughput, 3) and reduce the instrumental footprint. In order to address these key challenges, the analytical community has borrowed
technologies and design philosophies which has been used by the semiconductor industry over the past 20 years. By doing so, key
technological advances have been made which include the miniaturization of sensors and signal processing components which allows for the
efficient detection of nanoscale object. One can imagine that by decreasing the dimensions of a sensor to a scale similar to that of a
nanoscale object, the ultimate in sensitivity can potentially be achieved - the detection of single molecules. This talk highlights novel strategies
for the detection of single molecules using nanoporous membranes.
Confirmed:
Joshua Edel, Reader in (Bio)Sensing and Analytical Sciences, Department of Chemistry, Imperial College London, UK
Topic: Microfluidics for sorting and analysis of CTCs
Reserved:
Jean-Louis Viovy, Research Director Exceptional Class, Group Leader, Institut Curie, France
16:40-17:05 Context-driven Scent: Microfluidics for Health, Wellbeing and Fashion Applications
 Fragrances that are biosynced to a person's current emotional, mental and physical state and in a real-time manner relieves the
health condition
 Microfluidic devices in Wearable Technology that release fragrances as a personalised and controllable 'scent bubble'
 Applications in digital healthcare and fashion
Confirmed:
Jenny Tillotson, Founder of eScent; Visiting Scholar, University of Cambridge, UK
17:05 Chairman’s Closing Remarks and Conference Close
Venue
Novotel London West
1 Shortlands
Hammersmith International Centre
London W6 8DR
United Kingdom
A discounted group rate is available to all attendees.
Details of how to book are available on registration.
Space is limited and accommodation is available on a first come basis.
Agenda: Day Two continued – Friday 21st October, 2016

Making a poster presentation
Poster presentation sessions will take place in breaks and alongside the other breakout sessions of the conference. Your presentation
will be displayed in a dedicated area, with the other accepted posters from industry and academic presenters.
We also issue a poster ebook to all attendees with all abstracts in full.
Whether looking for funding, employment opportunities or simply wanting to share your work with a like-minded and focused group,
posters are an excellent way to take an active part in the congress.
In order to present a poster at the forum you need to be registered as a delegate. Please note that there is limited space available,
and poster space is assigned on a first come first served basis (subject to checks and successful registration).
For further information on submission, approval and the technical poster spec, please contact: submit@globalengage.co.uk or go
to http://www.globalengage.co.uk/microfluidics/posters.html
Global Engage – Other Related Events
2nd
Microfluidics Congress – October 20-21, 2016, London, UK
http://www.globalengage.co.uk/microfluidics.html
4th
qPCR & Digital PCR Congress – October 20-21, 2016, London, UK
http://www.globalengage.co.uk/qpcr.html
2nd
Microscopy Congress – November 14-15, 2016, London, UK
http://www.globalengage.co.uk/microscopy.html
Mass Spectrometry and Proteomics Congress – November 14-15, 2016, London, UK
http://globalengage.co.uk/mass-spectrometry.html
2nd
Microfluidics Congress USA – July 2017, Philadelphia, PA
http://www.globalengage.co.uk/microfluidics-usa.html
Poster Presentations

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