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CORE Group Meeting
MAY 7, 2019
Every Preemie—SCALE
SCALING, CATALYZING, ADVOCATING, LEARNING, EVIDENCE-DRIVEN
ENSURE THEY THRIVE
Nurturing care for small and sick newborns from
birth to 3 years – evidence review and synthesis
Why Inpatient Newborn Care?
Adapted from: Lawn JE, Davidge R, Paul VK, et al. Born too soon: care for the preterm baby
Nurturing Care
• Nurturing Care for Early Childhood Development. A
framework for helping children survive and thrive to
transform health and human potential—launched by
WHO, UNICEF, the World Bank Group and other partners in
2018 at the World Health Assembly
• Nurturing care defined as “a stable environment that is
sensitive to children’s health and nutritional needs,
with protection from threats, opportunities for early
learning, and interactions that are responsive,
emotionally supportive, and developmentally
stimulating”
• Developmentally supportive care improves
outcomes for newborns by placing them in a
nurturing, family-centred environment with
respect, minimal stimulation, and maximum
information-sharing between providers and
families.
• Pertains to all newborns, infants and children from 0 – 3
years
Reviewing the evidence
The evidence review and synthesis process includes two
components:
• A review of reviews from peer reviewed literature which
sought evidence about core elements of nurturing care
for in-facility small and sick newborns and post-
discharge care at the community level;
• Country case studies in high-, middle- and low-income
countries (Nepal, India, Philippines, Colombia, US,
Sweden, Rwanda and/or South Africa)
• A search for grey literature specific to case study countries
including policies, procedures, guidelines, laws and acts which
support the concepts of nurturing care.
Elements of developmentally supportive care
Evidence for key interventions—some highlights
INTERVENTION FINDINGS
Skin-to-skin/Kangaroo Care • Skin-to-skin/KC has positive and protective effects, particularly in LBW newborns, including mortality reduction,
prevention of sepsis, hypothermia and hypoglycaemia, reduced hospital readmission, exclusive breastfeeding and
improved biophysiological parameters.
• Involving fathers in skin-to-skin confers benefits for the whole family.
Nutrition
(breastmilk feeding and
breastfeeding)
• Early exposure to breastmilk confers benefit to preterm infants. Evidence is emerging that human milk has a positive
impact on preterm infants’ neurodevelopmental outcomes in the shorter- and longer-term through to adulthood.
• Targeting education and mass media campaigns to the local context and involving the wider community can enhance
breastfeeding practices.
Sensory environment • The sensory environment can provide both negative (light and noise) and positive (touch/massage) sensory stimulation.
• Cycled lighting appears safe and confers some short-term benefits (shorter length of stay).
• Reducing noise appears to confer benefit in enhancing quiet sleep states and physiologically stability.
• Early intervention, as simple and low cost as holding/touching, and parent involvement are important for positive
neurodevelopmental outcomes.
Reducing stress and pain • Assessment and management of pain is still poorly undertaken with reports that pain management (pharmacological or
non-pharmacological) is only undertaken about 50% of the time for painful procedures in neonatal units.
• Skin-to-skin confers benefit over sweet solution in preterm newborns. Skin-to-skin undertaken with any provider confers
benefit.
Supportive positioning • Positioning has short- and long-term benefits for development and for cognitive function.
• Positioning interventions that promote stability and reduce stress may have an impact on the cortex development in
preterm infants and should be encouraged.
INTERVENTION FINDINGS
Protecting and promoting sleep • Clustering of care and procedures (e.g. diaper change, eye care, repositioning of monitoring
device leads) is recommended to ensure complete sleep cycles and reduce stress-induced
physiological instability.
Protecting skin • Current evidence does not support the use of emollients for reducing invasive infection or
mortality in preterm infants in inpatient settings in any country defined by high, middle or
low income.
Age-appropriate stimulation and interactions
with health professionals, parents/
families/carers
• In the clinical context, the focus should be on interactions and activities that promote
maternal/parent - newborn contact and reduce stress for families while in hospital and
post discharge.
• Activities and care-giving that support positive interactions in the newborn inpatient and
early infancy period confers some benefit for cognitive function up to pre-school age.
Partnering with parents and families • Collaborating with parents, improved communication and involvement in decision-making
results in improved outcomes for both parents and neonates.
• Engaging parents early with good communication, education, participation in care giving and
decision-making benefits short term outcomes for newborns such as breastfeeding, growth,
readiness for discharge, distress and stress; and for parents: reduced stress, increased
confidence and positive parent-infant interactions.
Follow up and screening • In development
COUNTRY CASE STUDIES

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Presentation_Robb-McCord - Building Partnerships to provide nurturing care

  • 1. CORE Group Meeting MAY 7, 2019 Every Preemie—SCALE SCALING, CATALYZING, ADVOCATING, LEARNING, EVIDENCE-DRIVEN
  • 2. ENSURE THEY THRIVE Nurturing care for small and sick newborns from birth to 3 years – evidence review and synthesis
  • 3. Why Inpatient Newborn Care? Adapted from: Lawn JE, Davidge R, Paul VK, et al. Born too soon: care for the preterm baby
  • 4. Nurturing Care • Nurturing Care for Early Childhood Development. A framework for helping children survive and thrive to transform health and human potential—launched by WHO, UNICEF, the World Bank Group and other partners in 2018 at the World Health Assembly • Nurturing care defined as “a stable environment that is sensitive to children’s health and nutritional needs, with protection from threats, opportunities for early learning, and interactions that are responsive, emotionally supportive, and developmentally stimulating” • Developmentally supportive care improves outcomes for newborns by placing them in a nurturing, family-centred environment with respect, minimal stimulation, and maximum information-sharing between providers and families. • Pertains to all newborns, infants and children from 0 – 3 years
  • 5. Reviewing the evidence The evidence review and synthesis process includes two components: • A review of reviews from peer reviewed literature which sought evidence about core elements of nurturing care for in-facility small and sick newborns and post- discharge care at the community level; • Country case studies in high-, middle- and low-income countries (Nepal, India, Philippines, Colombia, US, Sweden, Rwanda and/or South Africa) • A search for grey literature specific to case study countries including policies, procedures, guidelines, laws and acts which support the concepts of nurturing care. Elements of developmentally supportive care
  • 6. Evidence for key interventions—some highlights INTERVENTION FINDINGS Skin-to-skin/Kangaroo Care • Skin-to-skin/KC has positive and protective effects, particularly in LBW newborns, including mortality reduction, prevention of sepsis, hypothermia and hypoglycaemia, reduced hospital readmission, exclusive breastfeeding and improved biophysiological parameters. • Involving fathers in skin-to-skin confers benefits for the whole family. Nutrition (breastmilk feeding and breastfeeding) • Early exposure to breastmilk confers benefit to preterm infants. Evidence is emerging that human milk has a positive impact on preterm infants’ neurodevelopmental outcomes in the shorter- and longer-term through to adulthood. • Targeting education and mass media campaigns to the local context and involving the wider community can enhance breastfeeding practices. Sensory environment • The sensory environment can provide both negative (light and noise) and positive (touch/massage) sensory stimulation. • Cycled lighting appears safe and confers some short-term benefits (shorter length of stay). • Reducing noise appears to confer benefit in enhancing quiet sleep states and physiologically stability. • Early intervention, as simple and low cost as holding/touching, and parent involvement are important for positive neurodevelopmental outcomes. Reducing stress and pain • Assessment and management of pain is still poorly undertaken with reports that pain management (pharmacological or non-pharmacological) is only undertaken about 50% of the time for painful procedures in neonatal units. • Skin-to-skin confers benefit over sweet solution in preterm newborns. Skin-to-skin undertaken with any provider confers benefit. Supportive positioning • Positioning has short- and long-term benefits for development and for cognitive function. • Positioning interventions that promote stability and reduce stress may have an impact on the cortex development in preterm infants and should be encouraged.
  • 7. INTERVENTION FINDINGS Protecting and promoting sleep • Clustering of care and procedures (e.g. diaper change, eye care, repositioning of monitoring device leads) is recommended to ensure complete sleep cycles and reduce stress-induced physiological instability. Protecting skin • Current evidence does not support the use of emollients for reducing invasive infection or mortality in preterm infants in inpatient settings in any country defined by high, middle or low income. Age-appropriate stimulation and interactions with health professionals, parents/ families/carers • In the clinical context, the focus should be on interactions and activities that promote maternal/parent - newborn contact and reduce stress for families while in hospital and post discharge. • Activities and care-giving that support positive interactions in the newborn inpatient and early infancy period confers some benefit for cognitive function up to pre-school age. Partnering with parents and families • Collaborating with parents, improved communication and involvement in decision-making results in improved outcomes for both parents and neonates. • Engaging parents early with good communication, education, participation in care giving and decision-making benefits short term outcomes for newborns such as breastfeeding, growth, readiness for discharge, distress and stress; and for parents: reduced stress, increased confidence and positive parent-infant interactions. Follow up and screening • In development

Editor's Notes

  1. Every Preemie – SCALE a 5-year USAID / W funded project run by a consortium of partners….PCI, Global Alliance to Prevent Prematurity and Stillbirth, and the American College of Nurse Midwives In our fifth and final year---designed to catalyze action for preterm birth and low birth weight in USAID’s 25 priority maternal and child health countries predominantly in sub-Saharan Africa Have been working with global partners including WHO, UNICEF, the London School, BMGF, MCSP, SNL and others on advocacy for increased attention to and action around preterm birth/LBW and over the past 18 months, inpatient newborn care
  2. Partners have been working over the past 18 months to put the spotlight on inpatient care for small/sick newborns. A few highlights include: Designing and implementing a situational assessment of inpatient newborn care in Bangladesh, Ghana, Rwanda, Tanzania, and Uganda The development and publication of the WHO document Survive and Thrive: transforming care for every small and sick newborn The development of standards of care for inpatient newborns at WHO An Evidence Synthesis of nurturing care for small/sick newborns during inpatient care – reviewing the evidence to inform the design of WHO guidelines and recommendations around nurturing care for the inpatient newborn Every newborn and child’s ability to thrive is the direct result of nurturing care and positive interaction with their environment. The brain is most vulnerable before birth and in the early years. Prematurity, birth complications, and severe infections such as meningitis result in high risk of disability and suboptimal development.  
  3. Surviving. More than 2.5 million babies died in 2017 from preventable causes, most notably prematurity, complications around the time of birth, infections and congenital conditions. Some died because the care they received was of poor quality; others because they received no health care at all. Thriving. Every year, 30 million newborns require specialized or intensive care in a hospital; those who survive often do so with preventable conditions and disabilities that will affect them for life. DISABILITY is a key marker of the quality of services received during inpatient care. HOWEVER, these newborns can and will thrive provided they are given high-quality inpatient care at the right time and in the right place, including follow-up care. Transforming. Cost–effective solutions exist for the main causes of neonatal death and disability. In line with the drive to achieve UHC, there must be improved human resource capacity, innovation, people-centred care, financial protection, and parent power and partnership.
  4. To achieve nurturing care, health professionals and caregivers need time and resources; facilitated by enabling environments of policies, services, community and family.(1) Enabling environments require capable caregivers, empowered communities, supportive services and enabling policies The newborn period is critical for early learning and even more important early/small newborns. These vulnerable newborns are at risk of neurodevelopmental delays without early, age-appropriate, neuroprotective interactions. Health professional, caregiver and family interactions within care facilities and post-discharge at home are important for both short- and long-term outcomes.
  5. To inform the WHO process to develop guidelines and recommendations for nurturing care it is important to understand the evidence around various elements of nurturing care. Peer reviewed lit review and country case studies combined with grey lit review For the evidence synthesis, the search was guided by the question, “What is the most recent information available from reviews on interventions/elements for developmentally supportive, family-centered, nurturing care for small and sick newborns”? Databases searched included Cochrane Library (CDSR), Pubmed, Scopus, Web of Science A total of 4147 publications were scanned by title and abstract, resulting in 578 references downloaded into a reference library. Following removal of duplicate references, 230 full text publications were scanned, resulting in 142 reviews eligible for inclusion. Reviews published between 2010 – 2019 were included in the search strategy. . Date parameters were 2010 – 2019 and we looked at birth to 59 days for newborns and young infants and follow up care up to 3 years of age
  6. Designed a framework to inform the search. Used the five components of nurturing care as seen on the previous slide and then built out 10 individual interventions directed at neuroprotective developmentally supportive care and a family-centered approach to care