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Updated findings of note include [22]:
Revision of the definition of IHC 2+ (equivocal) to the original FDA-approved
cr...](https://image.slidesharecdn.com/breastcanceraguidetoclinicalpracticepdfdrive-220506004455-bccc5b3e/75/breast-cancer-a-guide-to-clinical-practice-pdfdrive-pdf-31-2048.jpg?cb=1667572166)
![24
Table 1.6 (continued)
29–31]. ER/PgR positive, HER2 negative (node negative): Oncotype DX (Genomic Health Inc.,
Redwood...](https://image.slidesharecdn.com/breastcanceraguidetoclinicalpracticepdfdrive-220506004455-bccc5b3e/75/breast-cancer-a-guide-to-clinical-practice-pdfdrive-pdf-33-2048.jpg?cb=1667572166)
![29
Useful Biomarkers for the Decision of Adjuvant Systemic
Treatment in Early-Stage Breast Cancer [25]
ER/PgR Positive, ...](https://image.slidesharecdn.com/breastcanceraguidetoclinicalpracticepdfdrive-220506004455-bccc5b3e/75/breast-cancer-a-guide-to-clinical-practice-pdfdrive-pdf-38-2048.jpg?cb=1667572166)
![31
St Gallen 2017 panel did not respond to the question regarding extended adjuvant neratinib administration [3]. However,...](https://image.slidesharecdn.com/breastcanceraguidetoclinicalpracticepdfdrive-220506004455-bccc5b3e/75/breast-cancer-a-guide-to-clinical-practice-pdfdrive-pdf-40-2048.jpg?cb=1667572166)
![41
tinue AI therapy for a cumulative total of 5 years. This subject requires clarification [3]. e
After 5 years of continu...](https://image.slidesharecdn.com/breastcanceraguidetoclinicalpracticepdfdrive-220506004455-bccc5b3e/75/breast-cancer-a-guide-to-clinical-practice-pdfdrive-pdf-50-2048.jpg?cb=1667572166)
![44
lary lymph node involvement, in patients 50 years of age or older and in patients 50 years of age [3, 45, 49–52]. Accor...](https://image.slidesharecdn.com/breastcanceraguidetoclinicalpracticepdfdrive-220506004455-bccc5b3e/75/breast-cancer-a-guide-to-clinical-practice-pdfdrive-pdf-53-2048.jpg?cb=1667572166)
