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2012  Heart and Vascular
Outcomes Report
Heart and Vascular Outcomes               2012

W       elcome to the 2012 Heart and Vascular
        Outcomes Report for the Heart and Vascular
Center at Rogue Valley Medical Center. Among the
                                                             Rogue Regional to Asante Three Rivers and to Sky
                                                             Lakes Medical Center in Klamath Falls. The satellite
                                                             TV link allows active participation from the remote
                                                                                                                            the variety of databases and quality assessment
                                                                                                                            organizations in which we participate. A commitment
                                                                                                                            to ongoing quality improvement is essential; and as
many new aspects of our program is the hospital’s new        sites. We believe that top-quality patient care requires       discussed in the Quality: Our Approach section of this
name: Asante Rogue Regional Medical Center. It’s the         collaboration and teamwork. The teamwork begins                report, we describe the new Performance Improvement
same buildings and the same capable staff, but there         when the primary care physician refers a patient to one        in Cardiac Care Team (PICCT), which took the lead
is an increased emphasis on creating an integrated,          of our physicians; continues as that patient is served         in optimizing patient outcomes.
collaborative system of patient care.                        by our skilled nurses, technicians, and therapists; and
                                                             ends only after that patient has been treated and              As in previous editions, this report will also review
The cardiologists, cardiac surgeons, and vascular            educated and returns to his or her community.                  new technologies and procedures as well as provide
surgeons now all have offices in the same building—the                                                                      an overview of our programs.
Cardiovascular Institute on the Medford campus. This         We work hard to provide excellent cardiovascular
working arrangement facilitates communication and            care to the patients we serve. This report outlines our        We hope you find this information both interesting and
consultation among the various cardiovascular specialists.   approach to giving the patient a positive experience,          helpful in choosing the best treatment options for your
There is an active satellite cardiology program at Asante    and it details the statistics we use to objectively evaluate   patients. Together we can provide our patients the best
Three Rivers Medical Center in Grants Pass, staffed          our outcomes. How does one evaluate a cardiovascular           cardiovascular care.
by cardiologists who also manage patients in Medford.        program? It isn’t simple because many factors must
The weekly cardiology conference, which began in             be considered. In this report we present our statistics        —	The physicians and surgeons of the Heart and Vascular
1974, continues and is video-linked from Asante              supporting program volumes and outcomes. We describe             program at Asante Rogue Regional Medical Center
The Heart of Asante Rogue Regional Medical Center
                                       Cardiac disease is the leading cause of death in Oregon and California. Fortunately, effective therapy is available.
                                       Asante Rogue Regional Medical Center is a tax-exempt 378-licensed-bed facility created more than 50 years ago
                                       by and for the people of Southern Oregon and Northern California. Our heart and vascular program is nationally
                                       recognized and provides highly specialized heart and vascular care.
            Our Mission
                                            1958              1968             1973              1977               1981               2003                2005
        Asante exists to provide
      quality healthcare services in   Asante Rogue          Cardiac     First Cardiac   First open            First coronary         ASSET            Patient Tower
    a compassionate manner, valued     Regional opens    Intensive Care Catheterization heart surgery              balloon           program            constructed
      by the communities we serve.                         Unit opens Laboratory opens                          angioplasty         established



                                       Cardiac Facilities at Asante                                     Other Team Members
             Our Vision                Rogue Regional Medical Center                                    The first numeral represents the total number of people working
                                                                                                        in that department. Numerals in parentheses represent people
                                       •	 Cardiac Intensive Care Unit (16 beds)                         with 10 or more years of experience in that particular field.
  Asante will be recognized for        •	 Heart Center (40 telemetry beds)
medical excellence, for outstanding                                                                     •	 Operating room: 10 (7)
                                       •	 Cardiac catheterization laboratories
                                                                                                        •	 Cardiac perfusionists: 4 (4)
   customer service, and as a             ·	 2 outpatient labs
                                                                                                        •	 Cardiac surgery physician assistants: 4 (4)
       great place to work.               ·	 5 inpatient labs
                                                                                                        •	 Cardiac Intensive Care Unit: 54 (21)
                                       •	 Cardiovascular Recovery Unit
                                                                                                        •	 ICU-based nurse practitioner: 1 (0)
                                       •	 3 operating rooms for cardiovascular procedures
                                                                                                        •	 ICU-based physician assistant: 1 (0)
                                          ·	 2 dedicated to open heart procedures
          The Values in                   ·	 The region’s only endovascular angiographic suite
                                                                                                        •	 Cardiac catheterization laboratory
                                                                                                           ·	 Asante Rogue Regional: 20 (10)
         Which We Believe              •	 Imaging Services
                                                                                                           ·	 Asante Rogue Regional Cardiovascular Lab
                                          ·	Echocardiography
                                                                                                              at the Cardiovascular Institute: 12 (5)
    Excellence in everything we do        ·	 Stress nuclear
                                                                                                        •	 Cardiovascular recovery: 18 (6)
                                          ·	 Cardiac CT
            Respect for all                                                                             •	 Heart Center: 112 (36)
                                                                                                        •	 Cardiac Clinical Case Managers: 7 (6)
                                       Physicians (all board certified)
    Honesty in all our relationships   •	 13 cardiologists
                                                                                                        •	 Cardiac Rehabilitation: 7 (5)
                                                                                                        •	 Echocardiographers: 12 (7)
                                       •	 4 cardiothoracic surgeons
      Service to the community,                                                                         •	 Vascular ultrasound: 3 (2)
                                       •	 6 vascular surgeons
      physicians, and each other       •	 8 cardiac anesthesiologists
                                                                                                        •	 Stress testing: 13 (9)
                                                                                                        •	 Cardiopulmonary: 7 (3)
                                       •	 6 intensivists
           Teamwork always                                                                              •	 Clinical quality analysts: 6 (2)
                                       •	 15 hospitalists
                                                                                                        •	 STEMI nurse coordinator: 1 (0)
                                                                                                        •	 Critical Care clinical practice adviser: 1 (0)

4
Heart and Vascular Outcomes                                                                                                                               2012

Table of Contents

Welcome .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 3   Arrhythmias .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 25                 Natural History of Carotid Disease
The Heart of Asante Rogue Regional Medical Center .  .  .  .  .  .  .  .  . 4                                                                                                                                             Electrophysiology Program  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 25                                               Risk of Ipsilateral Stroke .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .                               45
Cardiac Facilities at Asante                                                                                                                                                                                              Diagnostic Electrophysiology Studies  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 25                                                                                 Who Should Be Considered for Carotid Stenting?  .  .  .  .  .  .  .  .  .  .  .                                                                                                                               45
Rogue Regional Medical Center .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 4                                                                    Tilt Table Testing  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 25         Criteria for Increased Surgical Risk .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .                                                                     45
Other Team Members  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 4                                    Intracardiac Ablation  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 26                        Current CMS Coverage for Carotid Stents .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .                                                                                                      45
                                                                                                                                                                                                                          Pulmonary Vein Antral Isolation  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 27                                                           Patients at Normal Surgical Risk:
Quality: Our Approach .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 6                                                                      Device Implantation .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 29
                                                                                                                                                                                                                                                                                                                                                                                                                                            NIH–Sponsored CREST Trial .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .                                                     46
Quality: How We Measure It and
                                                                                                                                                                                                                          Lead Extractions  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 29           Imaging .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 47
Continuously Strive to Improve .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 6
                                                                                                                                                                                                                          Indications for ICD Therapy .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 30                                                 Noninvasive Diagnostic Testing  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 47
Leapfrog Guidelines  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 6
                                                                                                                                                                                                                          Indications for Biventricular Pacing .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 30                                                                      Cardiac CT  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 49
CMS Quality Measures .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 7
                                                                                                                                                                                                                          New Anticoagulants: Dabigatran,                                                                                                                                                                                   Medicare Coverage for CT Coronary Angiography . . . . . . . . . . . 49
Coronary Artery Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8                                                                                                                       Rivaroxaban, and Apixaban .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 31
Cardiac Catheterization and Coronary Intervention .  .  .  .  .  .  .  .  .  .  . 8                                                                                                                                       Heart Transplant Care  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 31                              Preventive Cardiology .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 50
Myocardial Infarction: The ASSET Program .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 9                                                                                                                                                                                                                                                                                                                           Cardiac Rehabilitation, Preventive
ASSET Service Area .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 9                            Congenital Heart Disease  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 32                                                                                    Medicine, and Cardiac Education .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 50
The Chain of Survival .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 10                              Adult Congenital Heart Disease .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 32                                                             Cardiac Educators .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 51
Coronary Artery Stenting  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 12                                                                                                                                                                                                                                                                 Some Comments from Patients .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 51
                                                                                                                                                                                                                          Cardiac Surgery .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 33
Historical Myocardial Infarction Mortality Rates .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 13
                                                                                                                                                                                                                          Cardiothoracic Surgery .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 33                                 Therapies on the Horizon .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 52
National Recognition for the ASSET Program .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 14
                                                                                                                                                                                                                          Coronary Artery Bypass Graft  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 34                                                           Cryptogenic Stroke and Patent Foramen Ovale  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 52
Asante Rogue Regional Medical Center
                                                                                                                                                                                                                          Asante Valve Clinic .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 35                  Resistant Hypertension: Renal
Cardiovascular Lab at the Cardiovascular Institute .  .  .  .  .  .  .  .  .  .  .  . 16
                                                                                                                                                                                                                          Valve Procedures  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 36              Artery Radiofrequency Ablation .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 52
Radial Artery Access  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 17
                                                                                                                                                                                                                          Minimally Invasive Valve Procedures .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 36                                                                             Atrial Fibrillation: Preventing Stroke
Appropriate-Use Criteria for                                                                                                                                                                                                                                                                                                                                                                                                                Using a Left Atrial Appendage Occluder .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 53
Percutaneous Coronary Intervention  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 17                                                                                        Prosthetic Heart Valves  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 38
Fractional Flow Reserve Measurement                                                                                                                                                                                       3D Echocardiography .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 38                              Close Working Relationship with
with a Pressure Wire .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 19                            STS Risk Adjustment .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 39                        Oregon Health & Science University . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
Chronic Total Occlusion: Increasing Success                                                                                                                                                                               Endovascular Treatment of Thoracic Aortic Aneurysm  .  .  .  .  . 40
with Percutaneous Coronary Intervention  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 19
                                                                                                                                                                                                                                                                                                                                                                                                                                            Physician Biographies .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 54
                                                                                                                                                                                                                          Transmyocardial Revascularization  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 41
                                                                                                                                                                                                                                                                                                                                                                                                                                            Asante Cardiovascular and Thoracic Surgery  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 54
Percutaneous Cardiac Assist Devices:                                                                                                                                                                                      Atrial Fibrillation .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 41
Impella and Tandem Heart .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 20                                                                                                                                                                                                                                                                        Southern Oregon Cardiology, LLC  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 55
                                                                                                                                                                                                                          Maze Procedure .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 41
Impella Use in High-Risk Coronary Stenting  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 21                                                                                                                                                                                                                                                                                                                             Oregon Surgical Specialists, PC  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 60
Enhanced External Counterpulsation .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 22                                                                                         Vascular Surgery .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 42
                                                                                                                                                                                                                                                                                                                                                                                                                                            Contact Information .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 63
Hypothermia for Cardiac Arrest Patients .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 22                                                                                                   Comprehensive Vascular Care .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 42
                                                                                                                                                                                                                          Carotid Endarterectomy .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 44
Hospital Physicians  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . 24

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                5
Quality: Our Approach
 Quality: Our Approach


 Quality: How We Measure It                                 Leapfrog Guidelines
 and Continuously Strive to Improve
                                                            Coronary Artery Bypass Grafting                             Percutaneous Coronary Intervention
 Asante Rogue Regional Medical Center has
 a rigorous quality improvement program. Patient                 •	 Favorable hospital volume                             •	 Favorable hospital volume
 volumes and outcomes are carefully tracked and                     (450 or more procedures per year)                        (400 or more procedures per year)
 compared with external benchmarks. Quarterly                    •	 Participation in STS data collection                  •	 Participation in the American College of
 Morbidity and Mortality (M&M) conferences are                   •	 STS score exceeds the national average                   Cardiology National Cardiovascular Data
 held to review program statistics and individual patient           for risk-adjusted mortality                              Registry or > 80 percent adherence to the
 experiences. These conferences provide our physicians           •	 Minimum surgeon volume per year                          Leapfrog Expert Panel
 and staff with the opportunity to see what is going                for coronary artery bypass grafting (CABG)            •	 Endorsed Process Measures for Quality
 well and to identify areas in need of improvement.                 (100 cases per year)                                     Score better than the national average
 The recently organized Performance Improvement in                                                                           for risk-adjusted mortality
 Cardiac Care Team has been charged with identifying                                                                      •	 Minimum surgeon volume per year for
 areas in which the care process can be improved and                                                                         percutaneous coronary intervention (PCI)
 facilitating those improvements. The team consists         Leapfrog Evidence-Based                                          (75 cases per year)
                                                            Hospital Referral Safety Standard
 of a senior cardiologist, an experienced nurse data
 coordinator, and a clinical nurse specialist. The PICCT             Recommended Annual Volume
 organizes the quarterly M&M conferences, reviewing                      Asante Rogue Regional Medical Center Volume
                                                                                                                             American Heart Association’s
 and presenting statistical data as it becomes available.                                                               ACTION Registry-Get with the Guidelines®
 The team meets with various members of the care team
 to help solve problems and improve patient flow.
                                                                                                                          Award for Coronary Artery Disease:
                                                                                                                           Gold Status in 2008 to 2010 and
 Asante participates in a variety of national quality                                                                           Platinum Status in 2011
 improvement initiatives and databases, including the
 American College of Cardiology and the Society of
                                                            Volume




 Thoracic Surgeons (STS). We strive for a high level
 of compliance with subspecialty guidelines and with
 the Centers for Medicare & Medicaid Services (CMS)
 core measures for best practice guidelines.

 We support the transparent public reporting
 of healthcare quality data by participating in the
 following quality initiatives:                                                      Percutaneous        Aortic Valve
                                                                                        Coronary         Replacement
     •	 CMS Hospital Compare                                                          Intervention
        www.hospitalcompare.hhs.gov
                                                                          Coronary Artery    Abdominal Aortic
     •	 STS Consumer Reports                                              Bypass Gra ing     Aneurysm Repair
        www.sts.org
     •	 Healthgrades                                                                                                    Asante Rogue Regional Medical Center
        www.healthgrades.com                                                                                            performance improvement staff

 6
Heart and Vascular Outcomes                          2012

 CMS Quality Measures

 Acute Myocardial Infarction               CMS Quality Measure                                                                            Congestive Heart Failure                  CMS Quality Measure
             Top   Percent of Hospitals in the Nation         Asante Rogue Regional Medical Center                                                     Top     Percent of Hospitals in the Nation
                                                                                                                                                       Asante Rogue Regional Medical Center
Compliance




                                                                                                                                          Compliance
                                             Aspirin                                Smoking                       Primary Percutaneous
                                          at Discharge                              Cessation                     Coronary Intervention                                    Le Ventricular
                                                                                                                    within   Minutes                                        Assessment
                          Aspirin              ACE Inhibitor/Angiotensin Receptor                  Beta-Blocker
                         at Arrival             Blocker for Le Ventricular LV                      at Discharge                                                Clear Discharge     ACE Inhibitor/Angiotensin
                                                Systolic Dysfunction at Discharge                                                                                Instructions       Receptor Blocker for LV
                                                                                                                                                                                     Systolic Dysfunction
                                                                                                                                                                                         at Discharge
 Coronary Artery Bypass Gra Surgery                     CMS Quality Measure
             Top   Percent of Hospitals in the Nation         Asante Rogue Regional Medical Center

                                                                                                                                                              American Heart Association
                                                                                                                                                             Mission Lifeline Recognition for
Compliance




                                                                                                                                                             Heart Attack Care Performance
                                                                                                                                                              Achievement Award in 2012

                       Prophylactic                            Prophylactic                     Beta-Blocker within
                     Antibiotics within                  Antibiotics Discontinued                 Peri-Operative
                            Hour                             within     Hours                          Period
                                                                                                                                                           Acumentra Health Hospital
                                         Prophylactic                        Controlled A M                         Urinary Catheter                    Quality Awards for Excellent Care:
                                      Antibiotics Selection                   Post-Operative                          Removed by                        High Performance (95 percent) on
                                                                              Serum Glucose                       Post-Operative Day                    SCIP and Heart Failure Measures
                                                                                                                                                                in 2010 and 2011.
                       Thomson Reuters®
                   Top Quintile Health Systems
                         Award in 2011
                                                                                                                                                                                                          7
CORONARY ARTERY DISEASE
 Coronary Artery Disease


                                             Cardiac Catheterization and Coronary Intervention
                                             Cardiac catheterization facilities at Asante Rogue Regional Medical Center were established in 1973. Five catheterization
                                             and angiographic laboratories are dedicated to state-of-the-art diagnostic coronary angiography, coronary interventions,
                                             peripheral angiography and interventions, electrophysiologic procedures, and device implants. Board certification in
                                             cardiology is required of all cardiologists. Cardiologists who perform coronary interventions are board certified in
                                             interventional cardiology.

                                             Expertise is maintained by focusing procedural                Asante Rogue Regional Medical Center continues to
                                             experience within a small group of high-volume,               adhere to the PCI guidelines written and recommended
                                             experienced interventionalists whose low complication         by the American Heart Association, the American
                                             rates and excellent outcomes exceed national                  College of Cardiology, and the Society for Cardiac
                                             benchmarks. Coronary interventional volume for                Angiography and Interventions. These guidelines
                                             the institution and for each interventionalist exceeds        are as follows:*
                                             volume recommendations established by the Leapfrog
                                             Group, Thomson Healthcare, and the American College             •	 Operators perform at least 75 procedures at
                                             of Cardiology. A proven record of satisfactory outcomes            high-volume hospitals (more than 400 procedures
      Asante Rogue Regional Medical Center   and active participation in quality improvement                    per year) with on-site cardiac surgery.
                             cath lab team   programs is mandatory for all physicians.
                                                                                                             •	 Operators and institutions should have outcomes
                                                                                                                comparable to those reported in contemporary
                                                                                                                national data registries.
                                                         The five interventional
                                                    cardiologists are board certified                        •	 For ST-segment elevation myocardial infarction
                                                  in both cardiovascular disease and                            (STEMI), emergent PCI should be performed
                                                 interventional cardiology and provide                          by experienced operators who do more than 75
                                                                                                                elective PCI procedures per year and, ideally, at
                                                      around-the-clock coverage.                                least 11 PCI procedures for STEMI each year.
                                                                                                                Ideally, these procedures should be conducted in
            1981: Coronary                                                                                      institutions that perform more than 400 elective
    interventional program started                            14,751 coronary                                   PCIs per year and more than 36 primary PCI
                                                                                                                procedures for STEMI per year.
       at Asante Rogue Regional                          interventions have been
            Medical Center                                 performed since 1981.
                                                                                                           *Levin GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B,
                                                                                                            Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN,
                                                                                                            Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK,
                                                       13 cardiologists and four                            Ting HH. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary
                                                                                                            intervention: a report of the American College of Cardiology
                                                cardiothoracic surgeons work together                       Foundation/American Heart Association Task Force on Practice
                                                                                                            Guidelines and the Society for Cardiovascular Angiography and
                                                  to provide care around-the-clock.                         Interventions. Circulation. 2011;124:e574-e651.




8
Heart and Vascular Outcomes        2012

Myocardial Infarction: The ASSET Program                                                                                                               ASSET Regional STEMI receiving
                                                                                                                                                         hospital for primary PCI
ASSET (Acute ST-Segment Elevation Task Force) is a regional heart attack response team that coordinates the
simultaneous activation of paramedics, emergency departments, and the cardiac catheterization laboratory at Asante                                • Asante Rogue Regional Medical Center
Rogue Regional Medical Center for rapid identification, triage, and treatment of ST-segment elevation myocardial                                     Meets all American Heart Association
infarction patients (severe heart attacks) throughout Southern Oregon and Northern California. The ASSET program                                          Class I criteria for STEMI
has received national recognition for its dramatic reduction in death rates from heart attacks and is serving as a model
for other programs in development across the country. The program represents the integration of care supported by the                                ASSET STEMI receiving hospital for
                                                                                                                                                     primary PCI if patient requested
efforts of hospitals within the direct ASSET service area, hospitals within the regional support services area whose initial
management may include thrombolytic therapy followed by emergent transfer for possible rescue PCI, and those hospitals                             • Providence Medford Medical Center
having PCI capability supported by the cardiothoracic surgical program at Asante Rogue Regional Medical Center.
                                                                                                                                                     ASSET Service Area STEMI referring
                                                                                                                                                        hospitals for primary PCI
                                            ASSET Program Mission Statement                                                                           • Ashland Community Hospital
                                                                                                                                                         • Fairchild Medical Center
              To facilitate the accurate and rapid diagnosis, treatment, and transport
                                                                                                                                                   • Asante Three Rivers Medical Center
            of patients with acute ST-segment Elevation Myocardial Infarction (STEMI)
            from throughout the region to the Asante Rogue Regional Medical Center                                                                 ASSET Regional Support Services Area
                                                                                                                                                 hospitals providing thrombolytic therapy
                  cath lab for emergent percutaneous coronary intervention (PCI).                                                                with emergent transfer to Asante Rogue
                                                                                                                                                         Regional Medical Center
ASSET Service Area                                                                                                                                       • Curry General Hospital
                                                                                                                                                          • Lake District Hospital
          Coos Bay                                        O R E G O N                                                                                     • Sutter Coast Hospital
                                                                                                               ASSET Service Area
                         Coquille
         Bandon                                  Roseburg                                                      ASSET Regional                          Cardiothoracic Surgery Support
                          Myrtle Point                                                                         Support Services Area
                                                   Myrtle Creek                                                                                           • Mercy Medical Center
                                                                                                                                                        • Sky Lakes Medical Center
       Port Orford
                                                                                                                          Paisley                 Core Partnership—Emergency Services
                                                                                           Chiloquin
                                                 Grants Pass                                                                                       • American Medical Response (AMR)
                                     Redwood                                                                                                              • Ashland Fire & Rescue
                     Gold Beach
                                           Rogue River             Asante Rogue Regional Medical Center                                               • Jackson County Fire District 3
                                                   Medford                                   Altamont
                                                                           Klamath Falls                                                        • Medford Fire Department • Mercy Flights
                      Brookings         Cave Junction    Ashland                                                                Lakeview
                                                                                                                                                      • Northern Siskiyou Ambulance
             Harbor                                                                                    Malin
                                                                                Dorris                                                                   • Rogue River Fire District
                                                                     5                             Tulelake
                                    Happy Camp
         Crescent City
                                                             Yreka       Montague                                                                      Participating Heart Specialists
                                                  C A L I F O R N I A                                                                           • Asante Cardiovascular and Thoracic Surgery
                                                                                                                                                    • Southern Oregon Cardiology, LLC


                                                                                                                                                                                            9
CORONARY ARTERY DISEASE
 Coronary Artery Disease


The Chain of Survival

Gloria Ferguson, 52
Vancouver, Washington

Gloria, a math and science coordinator, was accompanying her 13-year-old son on a five-day
Boy Scout bicycling trip that began at Crater Lake National Park. On the first day, she was bicycling
and developed severe angina. A Boy Scout leader recognized the symptoms and drove her to the park’s
north entrance, where she lost consciousness soon after arrival. “Fast and deep” chest compressions
were promptly begun by two Boy Scout leaders. Seven park rangers quickly descended on the scene,
and a physician from a waiting car arrived as well. Approximately six to seven minutes after Gloria lost
consciousness, an automated external defibrillator (AED) was brought to the scene. Three shocks were
given over three to four minutes, with chest compressions in between, before a pulse was noted.
                                                                                                              Thrombotic occlusion in proximal                        Large thrombus
The Mercy Flights helicopter crew promptly            This resuscitation exemplifies what can                        left anterior descending                          in filter basket
arrived, diagnosed an acute anterolateral             happen when each link in the chain of survival
STEMI, and brought the critically ill patient         works: the prompt recognition of cardiac
directly to the Asante Rogue Regional Medical         symptoms by the Boy Scout leader; the quick
Center cardiac catheterization laboratory.            decision to head to the ranger station; the “fast and
Emergent coronary angiography revealed a              deep” chest compressions; the AED availability
thrombotic occlusion in the proximal LAD              and prompt and proper use; the rapid arrival and
(i.e., widowmaker lesion) (figure 1). Emergent        transport of a critically ill patient by helicopter;
mechanical thrombectomy was successful                the direct transport from the helipad to the
(figure 2) and reestablished flow, followed by        awaiting cath lab for emergent angiography,
stent deployment (figures 3 and 4). Gloria was        mechanical thrombectomy, and stent deployment           figure 1— Baseline angiogram           figure 2— Mechanical
in cardiogenic shock and required epinephrine         (door-to-balloon time of 29 minutes, including          showing a “widowmaker lesion”          thrombectomy
boluses, norepinephrine, dopamine, and an             intubation); the cardiac support with intra-aortic      (i.e., proximal thrombotic occlusion
intra-aortic balloon pump. She also had 12            balloon pumping; the subsequent hypothermia             in left anterior descending)                 Stent with large patent left
episodes of ventricular tachycardia/fibrillation      protocol to prevent brain injury; and the                                                                  anterior descending
requiring electrical cardioversion.                   round-the-clock vigilant care in the Cardiac
                                                      Intensive Care Unit. Her situation was precarious
She was then transferred to the Cardiac Intensive     throughout, and any failures along the way
Care Unit and improved over the next hour to          would probably have resulted in her death.
the point that hypothermia could be initiated.
She improved on a daily basis, was taken off
the ventilator five days after admission, and 12
days later was discharged home functional and
neurologically intact. Gloria is now back to work
full-time and has resumed playing golf.                                                                       figure 3— Balloon inflation and        figure 4— After stent deployment
                                                                                                              stent deployment


10
Heart and Vascular Outcomes              2012

       –          ASSET Patients Average Median Time to Treatment for STEMI

   Time at Referring Hospital          Paramedic Transport Time      Time from Emergency Department Door to Cardiac Cath Lab Door       Cardiac Cath Lab Arrival to Open Artery at
                                                                                                                                        Asante Rogue Regional Medical Center
                                                                                                                                                        minutes door–to–balloon time
                                            All ASSET Patients Jun      –Dec           n

                                                                                                                                                 minutes door–to–balloon time
                                                    All ASSET Patients Jun–Aug         n

                                                                                                                                                 minutes door–to–balloon time
                                                   All ASSET Patients Jan–Dec          n

                                                                                                                                      minutes door–to–balloon time
                                                   All ASSET Patients Jan–Dec          n

                                                                                                                                       minutes door–to–balloon time
                                                   All ASSET Patients Jan–Dec          n

                                                                                                                                    minutes door–to–balloon time
                                                   All ASSET Patients Jan–Dec          n

                                                                                                                        minutes door–to–balloon time
                                                   All ASSET Patients Jan–Dec          n

                                                                                                                                minutes door–to–balloon time
                                                    All ASSET Patients Jan–Dec         n
Time in Minutes



                                                                                               Arrival at Asante Rogue Regional Medical Center




Myocardial Infarction: Time Is Muscle
Cross-sectional image of the left ventricle during an inferior myocardial infarction


                                                                      Healthy heart muscle
                                                                      Dead heart muscle
                                                                      i e myocardial infarction heart a ack
                                                                      Blood within the heart
        hours                  hours               hours


                                                                                                                                                                                       11
CORONARY ARTERY DISEASE
 Coronary Artery Disease



Coronary Artery Stenting                                    ASSET STEMI Patients

                 Coronary artery atherosclerotic plaque        Transfer from Referring Hospital                Paramedic      Asante Rogue Regional Medical Center   Total




Low-profile stent and balloon advanced across blockage




            Balloon inflation results in stent deployment




     Balloon removed; stent maintains an open artery




STEMI In-Hospital Mortality                                 Patients with Door-to-Balloon Time within               Minutes




                                                                               –
        –
                                                            Total number of STEMI patients from 2003 through 2011 = 1,193




12
Heart and Vascular Outcomes  2012

Historical Myocardial Infarction Mortality Rates

Historical National Hospital Mortality Rates for ST-Elevation Myocardial Infarction Heart A ack



                                                                                                                                   3.9 percent is the mortality
                                                                                                                                   rate for 2011 and is also the
                                                                                                                                cumulative mortality rate for the
                                                                                                                               ASSET program since its inception
                                                                                                                                in 2003 (1,193 patients)—among
                      s                                   s                           s             ASSET Program at           the lowest reported in the nation.
                                                                                                  Asante Rogue Regional
                                                                                                     Medical Center
Source: Clinical Practice Guidelines AHCPR Publication No. 94-0602.                                     –     n



ST-Elevation Myocardial Infarction In-Hospital Mortality Comparison
Asante Rogue Regional Medical Center versus Other Hospitals




                                                                                                                                     89 percent of patients
                                                                                                                                  had hospital door–to–balloon
                                                                                                                                times within 90 minutes in 2011,
                                                                                                                                   making ASSET one of the
                                                                                                                                   elite myocardial infarction
                  National Registry of                        Asante Rogue Regional           ASSET Program at
               Myocardial Infarction                          Medical Center              Asante Rogue Regional
                                                                                                                                    programs in the country.
                   “Similar Hospitals”                                                    Medical Center n



                                          1,193 patients were treated at Asante
                                       Rogue Regional Medical Center for STEMI
                                       from June 2003 through December 2011.


                                                                                                                                                                   13
CORONARY ARTERY DISEASE
 Coronary Artery Disease


                                               National Recognition for the ASSET Program

                                               “An Approach to Shorten Time to Infarct Artery
                                               Patency in Patients with ST-Segment Elevation
                                               Myocardial Infarction”

                                               American Journal of Cardiology
                                               2007;99:1360-63.




                                                                                                “Integration of Pre-Hospital Electrocardiograms
                                                                                                and ST-Elevation Myocardial Infarction Receiving
      Asante Rogue Regional Medical Center                                                      Center (SRC) Networks: Impact on Door-to-Balloon
               Emergency Department staff                                                       Times Across 10 Independent Regions”

                                                                                                Journal of the American College of Cardiology:
                                                                                                Cardiovascular Interventions
                                                                                                2009;2(4):339-46.




                                                          Primary percutaneous coronary intervention is the most
                                                          complex, multidisciplinary, and time-sensitive therapeutic
                                                          intervention in the world of medicine today.
                                                              The process is measured in minutes.
                                                              The outcomes are measured in mortality.
                                                              Teamwork and smooth transitions are essential.
      Asante Rogue Regional Medical Center
     cardiopulmonary and enhanced external
                                                              — Ivan Rokos, MD
               counterpulsation (EECP) staff                    STEMI Systems, May 2007


14
Heart and Vascular Outcomes       2012

Annual Volume of Diagnostic Coronary Angiograms

  Asante Rogue Regional Medical Center        Asante Three Rivers Medical Center
  Asante Rogue Regional Medical Center Cardiovascular Lab at the Cardiovascular Institute   Combined Volume




                                                                                                                   Asante Rogue Regional Medical Center
                                                                                                                   cardiac studies staff




Annual Volume of Coronary Interventional Procedures
at Asante Rogue Regional Medical Center



                                                                 67,200 cardiac procedures have been
                                                                 performed at Asante Rogue Regional
                                                                      Medical Center since 1973.




                                                                                                                   Asante Rogue Regional Medical Center
                                                                                                                   cardiovascular recovery staff




                                                                                                                                                          15
CORONARY ARTERY DISEASE
 Coronary Artery Disease


Asante Rogue Regional Medical Center Cardiovascular Lab at the Cardiovascular Institute
Each year 13 cardiologists and six vascular surgeons perform a high volume of diagnostic cardiac catheterizations, peripheral
angiograms, and peripheral vascular interventions at the Asante Rogue Regional Medical Center Cardiovascular Lab.
Located in a comfortable, state-of-the-art facility within the outpatient facilities of the Cardiovascular Institute (CVI) on
the Medford campus, our lab allows elective studies to be performed conveniently; total stays average just four hours.




Peripheral Intervention Volume                                             Peripheral Angiography Volume                                           Cardiac Catheterization/Coronary Angiography Volume




                                                                           Includes carotid angiography, upper- and lower-extremity angiography,
                                                                           renal angiography, mesenteric angiography, and abdominal angiography
Includes upper- and lower-extremity angiography, renal angiography,
mesenteric angiography, and iliac angiography




                                       Peripheral Angiography Complications                                                                             No stroke, myocardial infarction,
                                           Stroke         Myocardial Infarction       Death                                                               or death occurred at the time
                                                                                                                                                        of coronary angiography/cardiac
                                                                                                                                                       catheterization from 2007 to 2011.




16
Heart and Vascular Outcomes  2012

Radial Artery Access
The radial artery is increasingly being used as the
access site to the arterial system when performing
coronary angiography, cardiac catheterization, and
percutaneous coronary intervention (i.e., coronary                     We use the American
stent) procedures. Historically, the brachial and                    College of Cardiology’s
femoral arteries have served as the points of access to
the arterial system. Radial artery access is associated            National Cardiovascular Data
with greater patient comfort, shorter bed rest times,               Registry database to track
shorter hospital stays, and less bleeding. If a coronary                patient outcomes.
intervention is performed via the radial approach,
same-day discharge is an option in some circumstances.
Femoral artery access is still used for complex
catheterization and interventions, depending on
the patient’s situation. Radial artery access was                                                                            Cath lab staff at CVI
first performed on a routine basis at Asante Rogue
Regional Medical Center in 2009 (the first program         Appropriate-Use Criteria for
in Southern Oregon) and is now routinely performed         Percutaneous Coronary Intervention
by five of the cardiologists.                              Over the past 10 years, there has been a paradigm
                                                           change in the treatment of patients with coronary
                                                           artery disease. In the past, if a patient had a 75 percent
                                                           coronary artery stenosis resulting in symptoms, a
                                                           cardiologist would have felt compelled to mechanically
                                                           fix that blockage. We now know it is the patient with                 A wide range of diagnostic
                                                           unstable or intractable symptoms who benefits. The                  and interventional procedures
                                                           American Heart Association and American College                         are performed in seven
                                                           of Cardiology evidence-based treatment guidelines                   state-of-the-art catheterization
                                                           have reviewed the large cardiology research trials
                                                           and have found that revascularization is beneficial in            laboratories—five at Asante Rogue
                                                           patients with acute coronary syndrome (i.e., plaque                    Regional Medical Center
                                                           rupture resulting in unstable angina, non-ST-segment                        and two at CVI.
                                                           elevation myocardial infarction, or ST-segment
                                                           elevation myocardial infarction), a high-risk stress
                                                           test or pressure wire assessment, congestive heart
Radial artery hemostasis after removing                    failure, or debilitating stable angina despite optimal
the radial artery access sheath                            medical therapy.




                                                                                                                                                             17
CORONARY ARTERY DISEASE
 Coronary Artery Disease




                                   Stent between fingers
                                   Courtesy of Cordis
                                                                             Pressure wire measurement
                                                                             of a hemodynamically significant
                                                                             coronary artery blockage
                                                                             Courtesy of Volcano




          Drug-eluting stent
     Courtesy of Fairman Studios
                                   Workhorse balloon for angioplasty
                                   Courtesy of Boston Scientific




                                                                             Intravascular ultrasound image
                                                                             (cross-sectional view) of a coronary artery
                                                                             with an eccentric atheromatous plaque
                                                                             Courtesy of Volcano
                                   Diamond-coated burr that spins at
                                   150,000 revolutions per minute to
                                   drill through heavily calcified lesions
                                   Courtesy of Boston Scientific


18
Heart and Vascular Outcomes                 2012

Fractional Flow Reserve                                      Chronic Total Occlusion: Increasing Success
Measurement with a Pressure Wire                             with Percutaneous Coronary Intervention
Coronary anatomy is best assessed by coronary
angiography. If a patient has unstable symptoms and                                                 Huntley Barns, 80
a severe stenosis, revascularization is clearly indicated.                                          Medford, Oregon
There are many other instances in which it is unclear
if a specific coronary lesion is the culprit in causing                                             Huntley is a retired pastor who had debilitating exertional angina
the patient’s symptoms. Coronary physiology can                                                     despite optimal medical therapy. He had a large 3+ reversible perfusion
be assessed using a pressure wire to measure the                                                    defect in the inferior wall. Wall thickening in the inferior wall confirmed
fractional flow reserve (FFR), which is the mean                                                    viability. Angiography revealed a chronic total occlusion in the mid-right
proximal pressure divided by the mean distal pressure.                                              coronary artery with collateral flow to the distal vessel (figure 1). New
A pressure wire is a 0.014-inch soft coronary wire                                                  coronary wire technology and techniques permitted crossing of the
with a pressure transducer on its tip. The pressure                                                 tough fibrous cap in the chronic total occlusion with subsequent stent
wire transducer is placed distal to the coronary lesion.                                            deployment. A good angiographic result was noted (figure 2), and the
The pressure distal to the coronary lesion is measured                                              patient was discharged home the next day.
via the pressure wire, and the pressure proximal to the
lesion is measured via the guiding catheter, permitting
measurement of the pressure gradient (i.e., FFR).
Adenosine (a short-acting vasodilator) is then given,
and the FFR is measured. A normal fractional flow
reserve is 1.0. Clinical outcome studies have shown
that a fractional flow reserve < 0.80 is best treated
with revascularization (i.e., coronary stent or
CABG surgery) and > 0.80 is best treated
with medical therapy.




      Pressure wire and intravascular
    ultrasonography provide additional
   physiologic and anatomic information
    regarding coronary artery plaques.                       figure 1— Chronic total occlusion (> 3 months              figure 2— Patent right coronary artery
                                                             old by definition) in mid-right coronary artery            after stent deployment




                                                                                                                                                                             19
CORONARY ARTERY DISEASE
 Coronary Artery Disease


              Percutaneous Cardiac Assist Devices: Impella and Tandem Heart
              For acutely ill patients with failing hearts, temporary cardiac assist devices can mean the difference between life and
              death. The Impella device is a low-profile pump (impeller) mounted on a pigtail catheter that is advanced across the
              aortic valve into the left ventricle via femoral artery access. It provides up to 2.5 liters per minute (L/min) of blood flow
              for cardiac support. The inlet is in the left ventricle, and the outlet is in the ascending aorta. Only the left ventricle
              can be supported at the moment. This device can be placed solely by the interventional cardiologist and is currently
              available. The Impella 4.0 L/min device should be available in February 2013.

              The Tandem Heart device can provide left                            These devices serve as a bridge to coronary
              heart support, right heart support, or both and is                  artery repair (e.g., high-risk percutaneous coronary
              placed either in the operating room or in the cardiac               intervention such as distal left main bifurcation stenting
              catheterization laboratory. A centrifugal pump is                   in a patient with low left ventricular ejection fraction
              used. For right heart support, the inflow cannula is                (LVEF) who is not felt to be a candidate for CABG
              placed in the right atrium and the outflow cannula                  surgery by the CT surgeons) or to provide time for
              in the pulmonary artery. For left heart support in the              the left ventricle to recover (e.g., acute anterolateral
              cath lab, the inflow cannula is placed in the left atrium           ST-elevation myocardial infarction with cardiogenic
              via a transseptal puncture, and the outflow cannula                 shock, metabolic acidosis, and pulmonary edema).
              is placed in the iliac artery. This device requires a team
              approach with the interventional cardiologist, the
              electrophysiologists, and the cardiothoracic surgeons.
              This device has already been used by the cardiothoracic
              surgeons and will hopefully be available for use
              in the cath lab in February 2013.




              Impella                                                                            Tandem Heart
              Courtesy of Abiomed                                                                Courtesy of Cardiac Assists


20
Heart and Vascular Outcomes               2012

Impella Use in High-Risk Coronary Stenting

                                        Ken Harrison, 55
                                        Yreka, California

                                        Ken was admitted with unstable angina and was subsequently diagnosed with a non-ST-elevation myocardial infarction and acute systolic
                                        heart failure. Despite optimal medical therapy, he had debilitating angina frequently at rest and simply walking across the room. Coronary
                                        angiography revealed a 95 percent stenosis in the distal left main trunk extending into both the left anterior descending and the left circumflex
                                        arteries. Given his liver disease, the cardiothoracic surgeons felt he was at prohibitively high risk for coronary artery bypass graft surgery.
                                        He then underwent high-risk percutaneous coronary intervention of the distal left main while simultaneously using a percutaneous
                                        left heart assist device (Abiomed Impella 2.5) for circulatory support (2.5 L/min).
                                        The coronary intervention involved simultaneous kissing-stent deployment into                                                       Balloon inflation
                                        both the left anterior descending and the left circumflex coronary arteries. Despite the
                                        14F access sheath and the complex nature of the intervention, Ken was discharged home
                                        the following day. Six months later he has no angina, is active, and has markedly
                                        improved his lifestyle. His liver function has also improved.

                                           Inflow port in
                                            left ventricle                              Left main
Outflow port in                                                                                              Left anterior
ascending aorta                                                       Catheter                                descending


                                                                                                                                           Stent deployment with
                                                                                                                                           simultaneous balloon inflation

                                                                                                                                                       Widely patent left main, left anterior
                                                                                                                                                           descending, and left circumflex

                                                           Severe                                                               Left
                                                           stenosis                                                       circumflex


     Impella device in left ventricle                                      Baseline coronary angiogram


                                   Approximate location
                                         of aortic valve



                                                                                                                                           Final angiogram after stent deployment



                                                                                                                                                                                          21
CORONARY ARTERY DISEASE
 Coronary Artery Disease


Enhanced External Counterpulsation                                                                                    Hypothermia for Cardiac Arrest Patients
For patients with debilitating chronic angina not            Although the mechanism at work is unclear                Cardiac arrest (ventricular fibrillation) results in
amenable to coronary revascularization (stent or             (possibly improved collateral flow), studies have        impaired blood flow to the brain. A prolonged
bypass surgery), enhanced external counterpulsation          repeatedly shown that 60 to 80 percent of patients       cardiac arrest (more than five minutes) can cause
(EECP) is a well-tolerated, atraumatic, noninvasive          experience the following results:                        brain damage (anoxic encephalopathy). On occasion
procedure that can reduce the symptoms of angina               •	 Reduced frequency and intensity of chest pain       the heart can be stabilized, but the patient remains
pectoris, presumably by increasing coronary blood              •	 Increased exercise tolerance                        unresponsive due to inadequate cerebral perfusion.
flow to ischemic areas of the heart.                           •	 Reduced need for anti-anginal medications           Inducing mild hypothermia to a core body temperature
                                                                  (such as nitroglycerin)                             of 33 degrees C via an external cooling blanket reduces
The EECP device uses a series of compressive cuffs             •	 Improved sense of well-being and quality of life    cerebral metabolism and edema and increases the
wrapped around the patient’s calves, thighs, and                                                                      likelihood of making a meaningful neurologic recovery.
buttocks and synchronizes their inflation and deflation      Patients typically undergo 35 one-hour sessions          This treatment has been proven to save one additional
to the cardiac cycle. During diastole the cuffs inflate      over a seven-week period and should first be evaluated   life for every seven patients treated and is currently
sequentially from the calves proximally, resulting           by a cardiologist. We have had 189 such patients since   recommended by the American Heart Association.
in augmented diastolic central aortic pressure and           the program was established in 2003.                     At Asante Rogue Regional Medical Center,
increased coronary perfusion pressure (when coronary                                                                  75 patients were treated from November 2006
artery flow is maximal). Rapid and simultaneous                                                                       through December 2011. Thirty-three patients
decompression of the cuffs at the onset of systole reduces                                                            survived, and 11 required rehabilitation care.
the systolic pressure and the cardiac workload.                     70 percent of patients noted
                                                                   an improvement in distance that
 Approved by the federal Food and Drug                              can be walked in six minutes.
   Administration (FDA) and Medicare

                                                             Change in Nitroglycerin Use n
Change in Chest Pain n
     Two Weeks a er               One Year Later                At Completion of Therapy        One Year Later
     Completion of Therapy




                                                                      Large        Slight    Unchanged     Worse
         Good        Slight   Unchanged            Worse           Reduction    Reduction
      Improvement Improvement                                        in Use       in Use                              Courtesy of Abbott Northwestern Hospital


22
Heart and Vascular Outcomes              2012

                                                                                    Henry Trujillo, 49
Cumulative Survival in the                                                          Grants Pass, Oregon
Hypothermia and Normothermia Groups
                                                                                    Henry is a US Navy veteran and a former truck driver who
     Hypothermia          Normothermia                                              had a sudden cardiac arrest while sleeping. His wife awoke to hear
        C                 No Temperature Adjustment                                 him say, “Ahhhh!” before he lost consciousness. His wife initiated
                                                                                    cardiopulmonary resuscitation (CPR) and paramedics found him in
                                                                                    ventricular fibrillation. Electrical cardioversion was successful, and
                                                                                    he required mechanical ventilation. Upon arrival at Asante Rogue
                                                                                    Regional Medical Center, Henry was comatose and his 12-lead
                                                                                    electrocardiogram (EKG) showed ST-elevation in leads V1 and V2
  Survival




                                                                                    consistent with myocardial infarction or Brugada syndrome (figure 1).
                                                                                    Emergent coronary angiography showed mild luminal irregularities
                                                                                    with no spasm, ulceration, or thrombus, confirming Brugada syndrome
                                                                                    (sodium channel mutation). The hypothermia protocol was initiated to
                                                                                    minimize cerebral edema. Henry’s neurologic function recovered four
                                                                                    days later, an intracardiac defibrillator was implanted, and he was
                                                                                    discharged home 10 days after his cardiac arrest.
                                   Days
Source: The Hypothermia after Cardiac Arrest Study Group,
New England Journal of Medicine. 2005;352:225-37.



Hypothermia Patient Survivors at
Asante Rogue Regional Medical Center




       Nov
        through       n           n           n             n
       Dec                                                      figure 1—12-lead EKG showed ST-elevation in leads V1 and V2
          n                                                     with right bundle branch block pattern
         Average age     years
         Average length of stay   days

                                                                                                                                                        23
Hospital Physicians
 Hospital Physicians




                                                                                      Asante Rogue Regional Medical Center intensivists
                                                                                      front row:	Petey Laohaburanakit, MD, FCCP; Tamara Dixon, FNP; Matthew Klee, MD;
                                                                                                    Somnath Ghosh, MD
                                                                                      back row:	James Stubenrauch, PA-C;, Francisco Paz, MD; Radek Dutkiewicz, MD
                                                                                      not pictured:	Krish Umapathy, MD

 Asante Rogue Regional Medical Center hospitalists
 front row:	Nha Le, MD; Erin Brender, MD; EeLin Wan, MD; and Elizabeth Hirni, DO;
 back row:	Jose Mondesi, MD; Ahsan Jaffar, MD; Thu Han Aung, MD; Jonathan Gell, MD;
               Tim Johnston, MD
 not pictured:	Ahmed T. Ahmed, MD; Tino Bauer, MD; Theresa Chan, MD;                                Six intensivists at Asante Rogue Regional
               Agnieszka Dobiecka, MD; Kenneth Sanford, MD; Donna Tribelhorn, MD                   Medical Center are board certified in critical
                                                                                                    care medicine; one is additionally board
                                                                                                         certified in pulmonary medicine.

                            15 hospitalists provide
                      care for many cardiac patients.
                     All hospitalists are board certified.                                            An intensivist is present in the hospital
                                                                                                   around-the-clock. Hospitals with an intensivist
                                                                                                   program are associated with better outcomes
                                                                                                            and lower mortality rates.



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2012 Heart and Vascular Outcomes Report

  • 1. 2012 Heart and Vascular Outcomes Report
  • 2.
  • 3. Heart and Vascular Outcomes 2012 W elcome to the 2012 Heart and Vascular Outcomes Report for the Heart and Vascular Center at Rogue Valley Medical Center. Among the Rogue Regional to Asante Three Rivers and to Sky Lakes Medical Center in Klamath Falls. The satellite TV link allows active participation from the remote the variety of databases and quality assessment organizations in which we participate. A commitment to ongoing quality improvement is essential; and as many new aspects of our program is the hospital’s new sites. We believe that top-quality patient care requires discussed in the Quality: Our Approach section of this name: Asante Rogue Regional Medical Center. It’s the collaboration and teamwork. The teamwork begins report, we describe the new Performance Improvement same buildings and the same capable staff, but there when the primary care physician refers a patient to one in Cardiac Care Team (PICCT), which took the lead is an increased emphasis on creating an integrated, of our physicians; continues as that patient is served in optimizing patient outcomes. collaborative system of patient care. by our skilled nurses, technicians, and therapists; and ends only after that patient has been treated and As in previous editions, this report will also review The cardiologists, cardiac surgeons, and vascular educated and returns to his or her community. new technologies and procedures as well as provide surgeons now all have offices in the same building—the an overview of our programs. Cardiovascular Institute on the Medford campus. This We work hard to provide excellent cardiovascular working arrangement facilitates communication and care to the patients we serve. This report outlines our We hope you find this information both interesting and consultation among the various cardiovascular specialists. approach to giving the patient a positive experience, helpful in choosing the best treatment options for your There is an active satellite cardiology program at Asante and it details the statistics we use to objectively evaluate patients. Together we can provide our patients the best Three Rivers Medical Center in Grants Pass, staffed our outcomes. How does one evaluate a cardiovascular cardiovascular care. by cardiologists who also manage patients in Medford. program? It isn’t simple because many factors must The weekly cardiology conference, which began in be considered. In this report we present our statistics — The physicians and surgeons of the Heart and Vascular 1974, continues and is video-linked from Asante supporting program volumes and outcomes. We describe program at Asante Rogue Regional Medical Center
  • 4. The Heart of Asante Rogue Regional Medical Center Cardiac disease is the leading cause of death in Oregon and California. Fortunately, effective therapy is available. Asante Rogue Regional Medical Center is a tax-exempt 378-licensed-bed facility created more than 50 years ago by and for the people of Southern Oregon and Northern California. Our heart and vascular program is nationally recognized and provides highly specialized heart and vascular care. Our Mission 1958 1968 1973 1977 1981 2003 2005 Asante exists to provide quality healthcare services in Asante Rogue Cardiac First Cardiac First open First coronary ASSET Patient Tower a compassionate manner, valued Regional opens Intensive Care Catheterization heart surgery balloon program constructed by the communities we serve. Unit opens Laboratory opens angioplasty established Cardiac Facilities at Asante Other Team Members Our Vision Rogue Regional Medical Center The first numeral represents the total number of people working in that department. Numerals in parentheses represent people • Cardiac Intensive Care Unit (16 beds) with 10 or more years of experience in that particular field. Asante will be recognized for • Heart Center (40 telemetry beds) medical excellence, for outstanding • Operating room: 10 (7) • Cardiac catheterization laboratories • Cardiac perfusionists: 4 (4) customer service, and as a · 2 outpatient labs • Cardiac surgery physician assistants: 4 (4) great place to work. · 5 inpatient labs • Cardiac Intensive Care Unit: 54 (21) • Cardiovascular Recovery Unit • ICU-based nurse practitioner: 1 (0) • 3 operating rooms for cardiovascular procedures • ICU-based physician assistant: 1 (0) · 2 dedicated to open heart procedures The Values in · The region’s only endovascular angiographic suite • Cardiac catheterization laboratory · Asante Rogue Regional: 20 (10) Which We Believe • Imaging Services · Asante Rogue Regional Cardiovascular Lab · Echocardiography at the Cardiovascular Institute: 12 (5) Excellence in everything we do · Stress nuclear • Cardiovascular recovery: 18 (6) · Cardiac CT Respect for all • Heart Center: 112 (36) • Cardiac Clinical Case Managers: 7 (6) Physicians (all board certified) Honesty in all our relationships • 13 cardiologists • Cardiac Rehabilitation: 7 (5) • Echocardiographers: 12 (7) • 4 cardiothoracic surgeons Service to the community, • Vascular ultrasound: 3 (2) • 6 vascular surgeons physicians, and each other • 8 cardiac anesthesiologists • Stress testing: 13 (9) • Cardiopulmonary: 7 (3) • 6 intensivists Teamwork always • Clinical quality analysts: 6 (2) • 15 hospitalists • STEMI nurse coordinator: 1 (0) • Critical Care clinical practice adviser: 1 (0) 4
  • 5. Heart and Vascular Outcomes 2012 Table of Contents Welcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Arrhythmias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Natural History of Carotid Disease The Heart of Asante Rogue Regional Medical Center . . . . . . . . . 4 Electrophysiology Program . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Risk of Ipsilateral Stroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Cardiac Facilities at Asante Diagnostic Electrophysiology Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Who Should Be Considered for Carotid Stenting? . . . . . . . . . . . 45 Rogue Regional Medical Center . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Tilt Table Testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Criteria for Increased Surgical Risk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Other Team Members . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Intracardiac Ablation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Current CMS Coverage for Carotid Stents . . . . . . . . . . . . . . . . . . . . . . 45 Pulmonary Vein Antral Isolation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Patients at Normal Surgical Risk: Quality: Our Approach . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Device Implantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 NIH–Sponsored CREST Trial . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Quality: How We Measure It and Lead Extractions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Imaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Continuously Strive to Improve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Indications for ICD Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Noninvasive Diagnostic Testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Leapfrog Guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Indications for Biventricular Pacing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Cardiac CT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 CMS Quality Measures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 New Anticoagulants: Dabigatran, Medicare Coverage for CT Coronary Angiography . . . . . . . . . . . 49 Coronary Artery Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Rivaroxaban, and Apixaban . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Cardiac Catheterization and Coronary Intervention . . . . . . . . . . . 8 Heart Transplant Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Preventive Cardiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Myocardial Infarction: The ASSET Program . . . . . . . . . . . . . . . . . . . . . . . . 9 Cardiac Rehabilitation, Preventive ASSET Service Area . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Congenital Heart Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Medicine, and Cardiac Education . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 The Chain of Survival . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Adult Congenital Heart Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Cardiac Educators . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Coronary Artery Stenting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Some Comments from Patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Cardiac Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Historical Myocardial Infarction Mortality Rates . . . . . . . . . . . . . . . . 13 Cardiothoracic Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Therapies on the Horizon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 National Recognition for the ASSET Program . . . . . . . . . . . . . . . . . . . . 14 Coronary Artery Bypass Graft . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 Cryptogenic Stroke and Patent Foramen Ovale . . . . . . . . . . . . . . . . 52 Asante Rogue Regional Medical Center Asante Valve Clinic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Resistant Hypertension: Renal Cardiovascular Lab at the Cardiovascular Institute . . . . . . . . . . . . 16 Valve Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Artery Radiofrequency Ablation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 Radial Artery Access . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Minimally Invasive Valve Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Atrial Fibrillation: Preventing Stroke Appropriate-Use Criteria for Using a Left Atrial Appendage Occluder . . . . . . . . . . . . . . . . . . . . . . . . . . 53 Percutaneous Coronary Intervention . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Prosthetic Heart Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 Fractional Flow Reserve Measurement 3D Echocardiography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 Close Working Relationship with with a Pressure Wire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 STS Risk Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Oregon Health & Science University . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 Chronic Total Occlusion: Increasing Success Endovascular Treatment of Thoracic Aortic Aneurysm . . . . . 40 with Percutaneous Coronary Intervention . . . . . . . . . . . . . . . . . . . . . . . . 19 Physician Biographies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Transmyocardial Revascularization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Asante Cardiovascular and Thoracic Surgery . . . . . . . . . . . . . . . . . . . 54 Percutaneous Cardiac Assist Devices: Atrial Fibrillation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Impella and Tandem Heart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Southern Oregon Cardiology, LLC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 Maze Procedure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Impella Use in High-Risk Coronary Stenting . . . . . . . . . . . . . . . . . . . . . . 21 Oregon Surgical Specialists, PC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60 Enhanced External Counterpulsation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Vascular Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Contact Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 Hypothermia for Cardiac Arrest Patients . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Comprehensive Vascular Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Carotid Endarterectomy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Hospital Physicians . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 5
  • 6. Quality: Our Approach Quality: Our Approach Quality: How We Measure It Leapfrog Guidelines and Continuously Strive to Improve Coronary Artery Bypass Grafting Percutaneous Coronary Intervention Asante Rogue Regional Medical Center has a rigorous quality improvement program. Patient • Favorable hospital volume • Favorable hospital volume volumes and outcomes are carefully tracked and (450 or more procedures per year) (400 or more procedures per year) compared with external benchmarks. Quarterly • Participation in STS data collection • Participation in the American College of Morbidity and Mortality (M&M) conferences are • STS score exceeds the national average Cardiology National Cardiovascular Data held to review program statistics and individual patient for risk-adjusted mortality Registry or > 80 percent adherence to the experiences. These conferences provide our physicians • Minimum surgeon volume per year Leapfrog Expert Panel and staff with the opportunity to see what is going for coronary artery bypass grafting (CABG) • Endorsed Process Measures for Quality well and to identify areas in need of improvement. (100 cases per year) Score better than the national average The recently organized Performance Improvement in for risk-adjusted mortality Cardiac Care Team has been charged with identifying • Minimum surgeon volume per year for areas in which the care process can be improved and percutaneous coronary intervention (PCI) facilitating those improvements. The team consists Leapfrog Evidence-Based (75 cases per year) Hospital Referral Safety Standard of a senior cardiologist, an experienced nurse data coordinator, and a clinical nurse specialist. The PICCT Recommended Annual Volume organizes the quarterly M&M conferences, reviewing Asante Rogue Regional Medical Center Volume American Heart Association’s and presenting statistical data as it becomes available. ACTION Registry-Get with the Guidelines® The team meets with various members of the care team to help solve problems and improve patient flow. Award for Coronary Artery Disease: Gold Status in 2008 to 2010 and Asante participates in a variety of national quality Platinum Status in 2011 improvement initiatives and databases, including the American College of Cardiology and the Society of Volume Thoracic Surgeons (STS). We strive for a high level of compliance with subspecialty guidelines and with the Centers for Medicare & Medicaid Services (CMS) core measures for best practice guidelines. We support the transparent public reporting of healthcare quality data by participating in the following quality initiatives: Percutaneous Aortic Valve Coronary Replacement • CMS Hospital Compare Intervention www.hospitalcompare.hhs.gov Coronary Artery Abdominal Aortic • STS Consumer Reports Bypass Gra ing Aneurysm Repair www.sts.org • Healthgrades Asante Rogue Regional Medical Center www.healthgrades.com performance improvement staff 6
  • 7. Heart and Vascular Outcomes 2012 CMS Quality Measures Acute Myocardial Infarction CMS Quality Measure Congestive Heart Failure CMS Quality Measure Top Percent of Hospitals in the Nation Asante Rogue Regional Medical Center Top Percent of Hospitals in the Nation Asante Rogue Regional Medical Center Compliance Compliance Aspirin Smoking Primary Percutaneous at Discharge Cessation Coronary Intervention Le Ventricular within Minutes Assessment Aspirin ACE Inhibitor/Angiotensin Receptor Beta-Blocker at Arrival Blocker for Le Ventricular LV at Discharge Clear Discharge ACE Inhibitor/Angiotensin Systolic Dysfunction at Discharge Instructions Receptor Blocker for LV Systolic Dysfunction at Discharge Coronary Artery Bypass Gra Surgery CMS Quality Measure Top Percent of Hospitals in the Nation Asante Rogue Regional Medical Center American Heart Association Mission Lifeline Recognition for Compliance Heart Attack Care Performance Achievement Award in 2012 Prophylactic Prophylactic Beta-Blocker within Antibiotics within Antibiotics Discontinued Peri-Operative Hour within Hours Period Acumentra Health Hospital Prophylactic Controlled A M Urinary Catheter Quality Awards for Excellent Care: Antibiotics Selection Post-Operative Removed by High Performance (95 percent) on Serum Glucose Post-Operative Day SCIP and Heart Failure Measures in 2010 and 2011. Thomson Reuters® Top Quintile Health Systems Award in 2011 7
  • 8. CORONARY ARTERY DISEASE Coronary Artery Disease Cardiac Catheterization and Coronary Intervention Cardiac catheterization facilities at Asante Rogue Regional Medical Center were established in 1973. Five catheterization and angiographic laboratories are dedicated to state-of-the-art diagnostic coronary angiography, coronary interventions, peripheral angiography and interventions, electrophysiologic procedures, and device implants. Board certification in cardiology is required of all cardiologists. Cardiologists who perform coronary interventions are board certified in interventional cardiology. Expertise is maintained by focusing procedural Asante Rogue Regional Medical Center continues to experience within a small group of high-volume, adhere to the PCI guidelines written and recommended experienced interventionalists whose low complication by the American Heart Association, the American rates and excellent outcomes exceed national College of Cardiology, and the Society for Cardiac benchmarks. Coronary interventional volume for Angiography and Interventions. These guidelines the institution and for each interventionalist exceeds are as follows:* volume recommendations established by the Leapfrog Group, Thomson Healthcare, and the American College • Operators perform at least 75 procedures at of Cardiology. A proven record of satisfactory outcomes high-volume hospitals (more than 400 procedures Asante Rogue Regional Medical Center and active participation in quality improvement per year) with on-site cardiac surgery. cath lab team programs is mandatory for all physicians. • Operators and institutions should have outcomes comparable to those reported in contemporary national data registries. The five interventional cardiologists are board certified • For ST-segment elevation myocardial infarction in both cardiovascular disease and (STEMI), emergent PCI should be performed interventional cardiology and provide by experienced operators who do more than 75 elective PCI procedures per year and, ideally, at around-the-clock coverage. least 11 PCI procedures for STEMI each year. Ideally, these procedures should be conducted in 1981: Coronary institutions that perform more than 400 elective interventional program started 14,751 coronary PCIs per year and more than 36 primary PCI procedures for STEMI per year. at Asante Rogue Regional interventions have been Medical Center performed since 1981. *Levin GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, 13 cardiologists and four Ting HH. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: a report of the American College of Cardiology cardiothoracic surgeons work together Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and to provide care around-the-clock. Interventions. Circulation. 2011;124:e574-e651. 8
  • 9. Heart and Vascular Outcomes 2012 Myocardial Infarction: The ASSET Program ASSET Regional STEMI receiving hospital for primary PCI ASSET (Acute ST-Segment Elevation Task Force) is a regional heart attack response team that coordinates the simultaneous activation of paramedics, emergency departments, and the cardiac catheterization laboratory at Asante • Asante Rogue Regional Medical Center Rogue Regional Medical Center for rapid identification, triage, and treatment of ST-segment elevation myocardial Meets all American Heart Association infarction patients (severe heart attacks) throughout Southern Oregon and Northern California. The ASSET program Class I criteria for STEMI has received national recognition for its dramatic reduction in death rates from heart attacks and is serving as a model for other programs in development across the country. The program represents the integration of care supported by the ASSET STEMI receiving hospital for primary PCI if patient requested efforts of hospitals within the direct ASSET service area, hospitals within the regional support services area whose initial management may include thrombolytic therapy followed by emergent transfer for possible rescue PCI, and those hospitals • Providence Medford Medical Center having PCI capability supported by the cardiothoracic surgical program at Asante Rogue Regional Medical Center. ASSET Service Area STEMI referring hospitals for primary PCI ASSET Program Mission Statement • Ashland Community Hospital • Fairchild Medical Center To facilitate the accurate and rapid diagnosis, treatment, and transport • Asante Three Rivers Medical Center of patients with acute ST-segment Elevation Myocardial Infarction (STEMI) from throughout the region to the Asante Rogue Regional Medical Center ASSET Regional Support Services Area hospitals providing thrombolytic therapy cath lab for emergent percutaneous coronary intervention (PCI). with emergent transfer to Asante Rogue Regional Medical Center ASSET Service Area • Curry General Hospital • Lake District Hospital Coos Bay O R E G O N • Sutter Coast Hospital ASSET Service Area Coquille Bandon Roseburg ASSET Regional Cardiothoracic Surgery Support Myrtle Point Support Services Area Myrtle Creek • Mercy Medical Center • Sky Lakes Medical Center Port Orford Paisley Core Partnership—Emergency Services Chiloquin Grants Pass • American Medical Response (AMR) Redwood • Ashland Fire & Rescue Gold Beach Rogue River Asante Rogue Regional Medical Center • Jackson County Fire District 3 Medford Altamont Klamath Falls • Medford Fire Department • Mercy Flights Brookings Cave Junction Ashland Lakeview • Northern Siskiyou Ambulance Harbor Malin Dorris • Rogue River Fire District 5 Tulelake Happy Camp Crescent City Yreka Montague Participating Heart Specialists C A L I F O R N I A • Asante Cardiovascular and Thoracic Surgery • Southern Oregon Cardiology, LLC 9
  • 10. CORONARY ARTERY DISEASE Coronary Artery Disease The Chain of Survival Gloria Ferguson, 52 Vancouver, Washington Gloria, a math and science coordinator, was accompanying her 13-year-old son on a five-day Boy Scout bicycling trip that began at Crater Lake National Park. On the first day, she was bicycling and developed severe angina. A Boy Scout leader recognized the symptoms and drove her to the park’s north entrance, where she lost consciousness soon after arrival. “Fast and deep” chest compressions were promptly begun by two Boy Scout leaders. Seven park rangers quickly descended on the scene, and a physician from a waiting car arrived as well. Approximately six to seven minutes after Gloria lost consciousness, an automated external defibrillator (AED) was brought to the scene. Three shocks were given over three to four minutes, with chest compressions in between, before a pulse was noted. Thrombotic occlusion in proximal Large thrombus The Mercy Flights helicopter crew promptly This resuscitation exemplifies what can left anterior descending in filter basket arrived, diagnosed an acute anterolateral happen when each link in the chain of survival STEMI, and brought the critically ill patient works: the prompt recognition of cardiac directly to the Asante Rogue Regional Medical symptoms by the Boy Scout leader; the quick Center cardiac catheterization laboratory. decision to head to the ranger station; the “fast and Emergent coronary angiography revealed a deep” chest compressions; the AED availability thrombotic occlusion in the proximal LAD and prompt and proper use; the rapid arrival and (i.e., widowmaker lesion) (figure 1). Emergent transport of a critically ill patient by helicopter; mechanical thrombectomy was successful the direct transport from the helipad to the (figure 2) and reestablished flow, followed by awaiting cath lab for emergent angiography, stent deployment (figures 3 and 4). Gloria was mechanical thrombectomy, and stent deployment figure 1— Baseline angiogram figure 2— Mechanical in cardiogenic shock and required epinephrine (door-to-balloon time of 29 minutes, including showing a “widowmaker lesion” thrombectomy boluses, norepinephrine, dopamine, and an intubation); the cardiac support with intra-aortic (i.e., proximal thrombotic occlusion intra-aortic balloon pump. She also had 12 balloon pumping; the subsequent hypothermia in left anterior descending) Stent with large patent left episodes of ventricular tachycardia/fibrillation protocol to prevent brain injury; and the anterior descending requiring electrical cardioversion. round-the-clock vigilant care in the Cardiac Intensive Care Unit. Her situation was precarious She was then transferred to the Cardiac Intensive throughout, and any failures along the way Care Unit and improved over the next hour to would probably have resulted in her death. the point that hypothermia could be initiated. She improved on a daily basis, was taken off the ventilator five days after admission, and 12 days later was discharged home functional and neurologically intact. Gloria is now back to work full-time and has resumed playing golf. figure 3— Balloon inflation and figure 4— After stent deployment stent deployment 10
  • 11. Heart and Vascular Outcomes 2012 – ASSET Patients Average Median Time to Treatment for STEMI Time at Referring Hospital Paramedic Transport Time Time from Emergency Department Door to Cardiac Cath Lab Door Cardiac Cath Lab Arrival to Open Artery at Asante Rogue Regional Medical Center minutes door–to–balloon time All ASSET Patients Jun –Dec n minutes door–to–balloon time All ASSET Patients Jun–Aug n minutes door–to–balloon time All ASSET Patients Jan–Dec n minutes door–to–balloon time All ASSET Patients Jan–Dec n minutes door–to–balloon time All ASSET Patients Jan–Dec n minutes door–to–balloon time All ASSET Patients Jan–Dec n minutes door–to–balloon time All ASSET Patients Jan–Dec n minutes door–to–balloon time All ASSET Patients Jan–Dec n Time in Minutes Arrival at Asante Rogue Regional Medical Center Myocardial Infarction: Time Is Muscle Cross-sectional image of the left ventricle during an inferior myocardial infarction Healthy heart muscle Dead heart muscle i e myocardial infarction heart a ack Blood within the heart hours hours hours 11
  • 12. CORONARY ARTERY DISEASE Coronary Artery Disease Coronary Artery Stenting ASSET STEMI Patients Coronary artery atherosclerotic plaque Transfer from Referring Hospital Paramedic Asante Rogue Regional Medical Center Total Low-profile stent and balloon advanced across blockage Balloon inflation results in stent deployment Balloon removed; stent maintains an open artery STEMI In-Hospital Mortality Patients with Door-to-Balloon Time within Minutes – – Total number of STEMI patients from 2003 through 2011 = 1,193 12
  • 13. Heart and Vascular Outcomes 2012 Historical Myocardial Infarction Mortality Rates Historical National Hospital Mortality Rates for ST-Elevation Myocardial Infarction Heart A ack 3.9 percent is the mortality rate for 2011 and is also the cumulative mortality rate for the ASSET program since its inception in 2003 (1,193 patients)—among s s s ASSET Program at the lowest reported in the nation. Asante Rogue Regional Medical Center Source: Clinical Practice Guidelines AHCPR Publication No. 94-0602. – n ST-Elevation Myocardial Infarction In-Hospital Mortality Comparison Asante Rogue Regional Medical Center versus Other Hospitals 89 percent of patients had hospital door–to–balloon times within 90 minutes in 2011, making ASSET one of the elite myocardial infarction National Registry of Asante Rogue Regional ASSET Program at Myocardial Infarction Medical Center Asante Rogue Regional programs in the country. “Similar Hospitals” Medical Center n 1,193 patients were treated at Asante Rogue Regional Medical Center for STEMI from June 2003 through December 2011. 13
  • 14. CORONARY ARTERY DISEASE Coronary Artery Disease National Recognition for the ASSET Program “An Approach to Shorten Time to Infarct Artery Patency in Patients with ST-Segment Elevation Myocardial Infarction” American Journal of Cardiology 2007;99:1360-63. “Integration of Pre-Hospital Electrocardiograms and ST-Elevation Myocardial Infarction Receiving Asante Rogue Regional Medical Center Center (SRC) Networks: Impact on Door-to-Balloon Emergency Department staff Times Across 10 Independent Regions” Journal of the American College of Cardiology: Cardiovascular Interventions 2009;2(4):339-46. Primary percutaneous coronary intervention is the most complex, multidisciplinary, and time-sensitive therapeutic intervention in the world of medicine today. The process is measured in minutes. The outcomes are measured in mortality. Teamwork and smooth transitions are essential. Asante Rogue Regional Medical Center cardiopulmonary and enhanced external — Ivan Rokos, MD counterpulsation (EECP) staff STEMI Systems, May 2007 14
  • 15. Heart and Vascular Outcomes 2012 Annual Volume of Diagnostic Coronary Angiograms Asante Rogue Regional Medical Center Asante Three Rivers Medical Center Asante Rogue Regional Medical Center Cardiovascular Lab at the Cardiovascular Institute Combined Volume Asante Rogue Regional Medical Center cardiac studies staff Annual Volume of Coronary Interventional Procedures at Asante Rogue Regional Medical Center 67,200 cardiac procedures have been performed at Asante Rogue Regional Medical Center since 1973. Asante Rogue Regional Medical Center cardiovascular recovery staff 15
  • 16. CORONARY ARTERY DISEASE Coronary Artery Disease Asante Rogue Regional Medical Center Cardiovascular Lab at the Cardiovascular Institute Each year 13 cardiologists and six vascular surgeons perform a high volume of diagnostic cardiac catheterizations, peripheral angiograms, and peripheral vascular interventions at the Asante Rogue Regional Medical Center Cardiovascular Lab. Located in a comfortable, state-of-the-art facility within the outpatient facilities of the Cardiovascular Institute (CVI) on the Medford campus, our lab allows elective studies to be performed conveniently; total stays average just four hours. Peripheral Intervention Volume Peripheral Angiography Volume Cardiac Catheterization/Coronary Angiography Volume Includes carotid angiography, upper- and lower-extremity angiography, renal angiography, mesenteric angiography, and abdominal angiography Includes upper- and lower-extremity angiography, renal angiography, mesenteric angiography, and iliac angiography Peripheral Angiography Complications No stroke, myocardial infarction, Stroke Myocardial Infarction Death or death occurred at the time of coronary angiography/cardiac catheterization from 2007 to 2011. 16
  • 17. Heart and Vascular Outcomes 2012 Radial Artery Access The radial artery is increasingly being used as the access site to the arterial system when performing coronary angiography, cardiac catheterization, and percutaneous coronary intervention (i.e., coronary We use the American stent) procedures. Historically, the brachial and College of Cardiology’s femoral arteries have served as the points of access to the arterial system. Radial artery access is associated National Cardiovascular Data with greater patient comfort, shorter bed rest times, Registry database to track shorter hospital stays, and less bleeding. If a coronary patient outcomes. intervention is performed via the radial approach, same-day discharge is an option in some circumstances. Femoral artery access is still used for complex catheterization and interventions, depending on the patient’s situation. Radial artery access was Cath lab staff at CVI first performed on a routine basis at Asante Rogue Regional Medical Center in 2009 (the first program Appropriate-Use Criteria for in Southern Oregon) and is now routinely performed Percutaneous Coronary Intervention by five of the cardiologists. Over the past 10 years, there has been a paradigm change in the treatment of patients with coronary artery disease. In the past, if a patient had a 75 percent coronary artery stenosis resulting in symptoms, a cardiologist would have felt compelled to mechanically fix that blockage. We now know it is the patient with A wide range of diagnostic unstable or intractable symptoms who benefits. The and interventional procedures American Heart Association and American College are performed in seven of Cardiology evidence-based treatment guidelines state-of-the-art catheterization have reviewed the large cardiology research trials and have found that revascularization is beneficial in laboratories—five at Asante Rogue patients with acute coronary syndrome (i.e., plaque Regional Medical Center rupture resulting in unstable angina, non-ST-segment and two at CVI. elevation myocardial infarction, or ST-segment elevation myocardial infarction), a high-risk stress test or pressure wire assessment, congestive heart Radial artery hemostasis after removing failure, or debilitating stable angina despite optimal the radial artery access sheath medical therapy. 17
  • 18. CORONARY ARTERY DISEASE Coronary Artery Disease Stent between fingers Courtesy of Cordis Pressure wire measurement of a hemodynamically significant coronary artery blockage Courtesy of Volcano Drug-eluting stent Courtesy of Fairman Studios Workhorse balloon for angioplasty Courtesy of Boston Scientific Intravascular ultrasound image (cross-sectional view) of a coronary artery with an eccentric atheromatous plaque Courtesy of Volcano Diamond-coated burr that spins at 150,000 revolutions per minute to drill through heavily calcified lesions Courtesy of Boston Scientific 18
  • 19. Heart and Vascular Outcomes 2012 Fractional Flow Reserve Chronic Total Occlusion: Increasing Success Measurement with a Pressure Wire with Percutaneous Coronary Intervention Coronary anatomy is best assessed by coronary angiography. If a patient has unstable symptoms and Huntley Barns, 80 a severe stenosis, revascularization is clearly indicated. Medford, Oregon There are many other instances in which it is unclear if a specific coronary lesion is the culprit in causing Huntley is a retired pastor who had debilitating exertional angina the patient’s symptoms. Coronary physiology can despite optimal medical therapy. He had a large 3+ reversible perfusion be assessed using a pressure wire to measure the defect in the inferior wall. Wall thickening in the inferior wall confirmed fractional flow reserve (FFR), which is the mean viability. Angiography revealed a chronic total occlusion in the mid-right proximal pressure divided by the mean distal pressure. coronary artery with collateral flow to the distal vessel (figure 1). New A pressure wire is a 0.014-inch soft coronary wire coronary wire technology and techniques permitted crossing of the with a pressure transducer on its tip. The pressure tough fibrous cap in the chronic total occlusion with subsequent stent wire transducer is placed distal to the coronary lesion. deployment. A good angiographic result was noted (figure 2), and the The pressure distal to the coronary lesion is measured patient was discharged home the next day. via the pressure wire, and the pressure proximal to the lesion is measured via the guiding catheter, permitting measurement of the pressure gradient (i.e., FFR). Adenosine (a short-acting vasodilator) is then given, and the FFR is measured. A normal fractional flow reserve is 1.0. Clinical outcome studies have shown that a fractional flow reserve < 0.80 is best treated with revascularization (i.e., coronary stent or CABG surgery) and > 0.80 is best treated with medical therapy. Pressure wire and intravascular ultrasonography provide additional physiologic and anatomic information regarding coronary artery plaques. figure 1— Chronic total occlusion (> 3 months figure 2— Patent right coronary artery old by definition) in mid-right coronary artery after stent deployment 19
  • 20. CORONARY ARTERY DISEASE Coronary Artery Disease Percutaneous Cardiac Assist Devices: Impella and Tandem Heart For acutely ill patients with failing hearts, temporary cardiac assist devices can mean the difference between life and death. The Impella device is a low-profile pump (impeller) mounted on a pigtail catheter that is advanced across the aortic valve into the left ventricle via femoral artery access. It provides up to 2.5 liters per minute (L/min) of blood flow for cardiac support. The inlet is in the left ventricle, and the outlet is in the ascending aorta. Only the left ventricle can be supported at the moment. This device can be placed solely by the interventional cardiologist and is currently available. The Impella 4.0 L/min device should be available in February 2013. The Tandem Heart device can provide left These devices serve as a bridge to coronary heart support, right heart support, or both and is artery repair (e.g., high-risk percutaneous coronary placed either in the operating room or in the cardiac intervention such as distal left main bifurcation stenting catheterization laboratory. A centrifugal pump is in a patient with low left ventricular ejection fraction used. For right heart support, the inflow cannula is (LVEF) who is not felt to be a candidate for CABG placed in the right atrium and the outflow cannula surgery by the CT surgeons) or to provide time for in the pulmonary artery. For left heart support in the the left ventricle to recover (e.g., acute anterolateral cath lab, the inflow cannula is placed in the left atrium ST-elevation myocardial infarction with cardiogenic via a transseptal puncture, and the outflow cannula shock, metabolic acidosis, and pulmonary edema). is placed in the iliac artery. This device requires a team approach with the interventional cardiologist, the electrophysiologists, and the cardiothoracic surgeons. This device has already been used by the cardiothoracic surgeons and will hopefully be available for use in the cath lab in February 2013. Impella Tandem Heart Courtesy of Abiomed Courtesy of Cardiac Assists 20
  • 21. Heart and Vascular Outcomes 2012 Impella Use in High-Risk Coronary Stenting Ken Harrison, 55 Yreka, California Ken was admitted with unstable angina and was subsequently diagnosed with a non-ST-elevation myocardial infarction and acute systolic heart failure. Despite optimal medical therapy, he had debilitating angina frequently at rest and simply walking across the room. Coronary angiography revealed a 95 percent stenosis in the distal left main trunk extending into both the left anterior descending and the left circumflex arteries. Given his liver disease, the cardiothoracic surgeons felt he was at prohibitively high risk for coronary artery bypass graft surgery. He then underwent high-risk percutaneous coronary intervention of the distal left main while simultaneously using a percutaneous left heart assist device (Abiomed Impella 2.5) for circulatory support (2.5 L/min). The coronary intervention involved simultaneous kissing-stent deployment into Balloon inflation both the left anterior descending and the left circumflex coronary arteries. Despite the 14F access sheath and the complex nature of the intervention, Ken was discharged home the following day. Six months later he has no angina, is active, and has markedly improved his lifestyle. His liver function has also improved. Inflow port in left ventricle Left main Outflow port in Left anterior ascending aorta Catheter descending Stent deployment with simultaneous balloon inflation Widely patent left main, left anterior descending, and left circumflex Severe Left stenosis circumflex Impella device in left ventricle Baseline coronary angiogram Approximate location of aortic valve Final angiogram after stent deployment 21
  • 22. CORONARY ARTERY DISEASE Coronary Artery Disease Enhanced External Counterpulsation Hypothermia for Cardiac Arrest Patients For patients with debilitating chronic angina not Although the mechanism at work is unclear Cardiac arrest (ventricular fibrillation) results in amenable to coronary revascularization (stent or (possibly improved collateral flow), studies have impaired blood flow to the brain. A prolonged bypass surgery), enhanced external counterpulsation repeatedly shown that 60 to 80 percent of patients cardiac arrest (more than five minutes) can cause (EECP) is a well-tolerated, atraumatic, noninvasive experience the following results: brain damage (anoxic encephalopathy). On occasion procedure that can reduce the symptoms of angina • Reduced frequency and intensity of chest pain the heart can be stabilized, but the patient remains pectoris, presumably by increasing coronary blood • Increased exercise tolerance unresponsive due to inadequate cerebral perfusion. flow to ischemic areas of the heart. • Reduced need for anti-anginal medications Inducing mild hypothermia to a core body temperature (such as nitroglycerin) of 33 degrees C via an external cooling blanket reduces The EECP device uses a series of compressive cuffs • Improved sense of well-being and quality of life cerebral metabolism and edema and increases the wrapped around the patient’s calves, thighs, and likelihood of making a meaningful neurologic recovery. buttocks and synchronizes their inflation and deflation Patients typically undergo 35 one-hour sessions This treatment has been proven to save one additional to the cardiac cycle. During diastole the cuffs inflate over a seven-week period and should first be evaluated life for every seven patients treated and is currently sequentially from the calves proximally, resulting by a cardiologist. We have had 189 such patients since recommended by the American Heart Association. in augmented diastolic central aortic pressure and the program was established in 2003. At Asante Rogue Regional Medical Center, increased coronary perfusion pressure (when coronary 75 patients were treated from November 2006 artery flow is maximal). Rapid and simultaneous through December 2011. Thirty-three patients decompression of the cuffs at the onset of systole reduces survived, and 11 required rehabilitation care. the systolic pressure and the cardiac workload. 70 percent of patients noted an improvement in distance that Approved by the federal Food and Drug can be walked in six minutes. Administration (FDA) and Medicare Change in Nitroglycerin Use n Change in Chest Pain n Two Weeks a er One Year Later At Completion of Therapy One Year Later Completion of Therapy Large Slight Unchanged Worse Good Slight Unchanged Worse Reduction Reduction Improvement Improvement in Use in Use Courtesy of Abbott Northwestern Hospital 22
  • 23. Heart and Vascular Outcomes 2012 Henry Trujillo, 49 Cumulative Survival in the Grants Pass, Oregon Hypothermia and Normothermia Groups Henry is a US Navy veteran and a former truck driver who Hypothermia Normothermia had a sudden cardiac arrest while sleeping. His wife awoke to hear C No Temperature Adjustment him say, “Ahhhh!” before he lost consciousness. His wife initiated cardiopulmonary resuscitation (CPR) and paramedics found him in ventricular fibrillation. Electrical cardioversion was successful, and he required mechanical ventilation. Upon arrival at Asante Rogue Regional Medical Center, Henry was comatose and his 12-lead electrocardiogram (EKG) showed ST-elevation in leads V1 and V2 Survival consistent with myocardial infarction or Brugada syndrome (figure 1). Emergent coronary angiography showed mild luminal irregularities with no spasm, ulceration, or thrombus, confirming Brugada syndrome (sodium channel mutation). The hypothermia protocol was initiated to minimize cerebral edema. Henry’s neurologic function recovered four days later, an intracardiac defibrillator was implanted, and he was discharged home 10 days after his cardiac arrest. Days Source: The Hypothermia after Cardiac Arrest Study Group, New England Journal of Medicine. 2005;352:225-37. Hypothermia Patient Survivors at Asante Rogue Regional Medical Center Nov through n n n n Dec figure 1—12-lead EKG showed ST-elevation in leads V1 and V2 n with right bundle branch block pattern Average age years Average length of stay days 23
  • 24. Hospital Physicians Hospital Physicians Asante Rogue Regional Medical Center intensivists front row: Petey Laohaburanakit, MD, FCCP; Tamara Dixon, FNP; Matthew Klee, MD; Somnath Ghosh, MD back row: James Stubenrauch, PA-C;, Francisco Paz, MD; Radek Dutkiewicz, MD not pictured: Krish Umapathy, MD Asante Rogue Regional Medical Center hospitalists front row: Nha Le, MD; Erin Brender, MD; EeLin Wan, MD; and Elizabeth Hirni, DO; back row: Jose Mondesi, MD; Ahsan Jaffar, MD; Thu Han Aung, MD; Jonathan Gell, MD; Tim Johnston, MD not pictured: Ahmed T. Ahmed, MD; Tino Bauer, MD; Theresa Chan, MD; Six intensivists at Asante Rogue Regional Agnieszka Dobiecka, MD; Kenneth Sanford, MD; Donna Tribelhorn, MD Medical Center are board certified in critical care medicine; one is additionally board certified in pulmonary medicine. 15 hospitalists provide care for many cardiac patients. All hospitalists are board certified. An intensivist is present in the hospital around-the-clock. Hospitals with an intensivist program are associated with better outcomes and lower mortality rates. 24