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ORGANOLEPTIC EVALUATION
Organoleptic (lit. impression on the organs) refers to
evaluation by means of the organs of sense ...
 For convenience of description the macroscopic
characteristics of a drug maybe divided into
following headings.
 Shape ...
SHAPE AND SIZE OF CRUDE DRUGS
 Crude drugs can be of different shapes etc.
 Cylindrical (Sarsaparilla)
 Sub cylindrical...
 Conical (Aconite)
 Fusiform (Sweet potato)
 Ovoid (Cactus)
 Pyriform (Jalap)
 Terrete (Orchid)
 Disc shape (Calumba)
SIZE OF CRUDE DRUGS
 Size of crude drugs may vary because their length,
diameter and width is different. Size of crude
dr...
FRACTURE
There are three types of fracture.
 Complete fracture :
the drug breaks completely when pressure is
applied.
 I...
Nature of fracture
Nature of fractured surface is as important as fracture.
 Even: smooth surface
 Uneven: irregularly b...
External markings:
How the drug looks externally. They may be classified as
 Furrows: alternate ridges and valleys due to...
ODOR
It is a very sensitive criteria based on individual
perception. Odor may be divided into two main classes
 Distinct ...
Taste
Usually crude drugs cannot be tasted because some may
be poisonous or may cause allergic reactions. But some
tastes ...
 A handbook of pharmacognosy by V.E, Tyler
 Evaluation of crude drugs, mono or polyherbal formulation
www.pharmatutor.or...
Organoleptic evaluation of crude drugs
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Organoleptic evaluation of crude drugs

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Organoleptic evaluation of Crude drugs
Size
Shape
Colour
Odour
Taste
Fracture
External & Internal markings

Publicada em: Saúde e medicina
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Organoleptic evaluation of crude drugs

  1. 1. ORGANOLEPTIC EVALUATION Organoleptic (lit. impression on the organs) refers to evaluation by means of the organs of sense and includes the macroscopic appearance of the drug, its odour and taste, occasionally the sound or snap of its fracture and the feel of the drug to touch.
  2. 2.  For convenience of description the macroscopic characteristics of a drug maybe divided into following headings.  Shape and size  Colour  Fracture  External markings  Odour and taste
  3. 3. SHAPE AND SIZE OF CRUDE DRUGS  Crude drugs can be of different shapes etc.  Cylindrical (Sarsaparilla)  Sub cylindrical (Podophyllum)
  4. 4.  Conical (Aconite)  Fusiform (Sweet potato)  Ovoid (Cactus)
  5. 5.  Pyriform (Jalap)  Terrete (Orchid)  Disc shape (Calumba)
  6. 6. SIZE OF CRUDE DRUGS  Size of crude drugs may vary because their length, diameter and width is different. Size of crude drugs can be measured by vernier callipers in cm & mm. COLOUR  External colour of crude drugs is mostly greyish brown and internal colour is whitish yellow, external colour maybe yellowish grey, yellowish brown, reddish orange to brown black. It is often more or less grey from clay dust.
  7. 7. FRACTURE There are three types of fracture.  Complete fracture : the drug breaks completely when pressure is applied.  Incomplete fracture: the drug does not break completely when fracture is applied.  Short fracture: the drug breaks with a snap sound when pressure is applied.
  8. 8. Nature of fracture Nature of fractured surface is as important as fracture.  Even: smooth surface  Uneven: irregularly broken surface  Granular : grain like appearance  Hard: a compact surface  Horny: Horn like surface  Powdered: powdery surface  Resinous: smooth glossy surface  Conchodial : a resinous surface having the surfaces curved in convex and concave form.
  9. 9. External markings: How the drug looks externally. They may be classified as  Furrows: alternate ridges and valleys due to shrinkage of internal parts caused by drying  Wrinkles: fine or delicate furrows  Annulations: transverse ring like markings on exterior  Fissures: splits extending into tissues  Nodule: rounded outgrowth on surface  Scars: produced due to injury or cut
  10. 10. ODOR It is a very sensitive criteria based on individual perception. Odor may be divided into two main classes  Distinct odor e.g. camphor and clove  Indistinct odor depending upon the amount of volatile constituents the drug possesses. The different odors may include 1. Aromatic odor 2. Alliaceous 3. Camphoraceous 4. Spicy etc.
  11. 11. Taste Usually crude drugs cannot be tasted because some may be poisonous or may cause allergic reactions. But some tastes which are known are:  Sweet taste e.g. liquorice, honey  Acidic/sour taste e.g. lemon  Saline/salty taste e.g. kashar  Acrid taste : unpleasant and irritating e.g. Jalap
  12. 12.  A handbook of pharmacognosy by V.E, Tyler  Evaluation of crude drugs, mono or polyherbal formulation www.pharmatutor.org/.../evaluation of crude drugs  EVALUATION OF CRUDE DRUGS|authorSTREAM www.authorstream.com/.../drfateha-2076158-evaluation-crude- drugs/  Evaluation of crude drugs – OpenStudy .com assets.openstudy.com/.../54b24d9ae4b0bdcb3ccd4df2- References:

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