Filoviridae
Filovirus only virus having reservoir host unknown

Properties
Pleomorphic, long filamentus, some time
branched form or 6 shape or Circular form
Single stranded RNA (Reo, Birna)
Negative, Non segmented
Enveloped- (Picorna,Calci,Astro,Reo,Birna- NE)
Sensitive to ether
Largest virus of all negative sense virus

Helical symmetry (Picorna, Calci, Astro, Reo,
Birna, Togo, Flavi, Retro)
Replication - cytoplasmic, (Borna, Orthromyxo)

Classification
1. Marburg like virus
2. Ebola virus
-Zaire
-Sudan
-Cote ivoire
- Reston

Marburg & Ebola Haemorrhagic fever
Cause by Filovirus
Produce disease in Human
Petechiae echymoses haemorrhagic pharyngitis
Uncontrolled bleeding from melena
Vomiting
Biosefty leval 4 pathogen

Properties
Size 90 nm
Single stranded RNA (Reo, Birna)
Negative, Non segmented
Enveloped- (Picorna,Calci,Astro,Reo,Birna- NE)
Sensitive to ether

Helical symmetry (Picorna, Calci, Astro, Reo,
Birna, Togo, Flavi, Retro)
Replication - Nucleus, (Borna, Orthromyxo)

Neurological disease of Horse
Borna disease in horse and sheep
Menigoencephalitis
Rodent and wild birda act as reservoir host
Staggering disease
Intra nuclear inclusion bodies in brain