3. INTRODUCTION
Elevated ICP
Obese young
women
Papilloedema
Corbett JJ, Savino PJ, Thompson HS, Kansu T, Schatz NJ, Orr LS, et al. Visual loss in pseudotumor cerebri. Follow-up of 57 patients from five to 41 years and a profile of 14 patients with permanent severe visual loss. Arch Neurol
4. EPIDEMIOLOGY
12–20 per 100 000 people per year in young obese women
0·5–2 per 100 000 people per year in the general population
Markey KA, Mollan SP, Jensen RH, Sinclair AJ. Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. The Lancet Neurology. 2016 Jan 1;15(1):78-91.
5. PATHOGENESIS
Markey KA, Mollan SP, Jensen RH, Sinclair AJ. Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. The Lancet Neurology. 2016 Jan 1;15(1):78-91.
6. ETIOLOGY (FOR SECONDARY IIH)
Beri S, Chandratre S, Chow G. Familial idiopathic intracranial hypertension with variable phenotype. Eur J Paediatr Neurol 2011; 15: 81–83.
7. CLINICAL PRESENTATION
Markey KA, Mollan SP, Jensen RH, Sinclair AJ. Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. The Lancet Neurology. 2016 Jan 1;15(1):78-91.
8. DIAGNOSTIC CRITERIA
Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology 2013; 81: 1159–65.
9. Markey KA, Mollan SP, Jensen RH, Sinclair AJ. Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. The Lancet Neurology. 2016 Jan 1;15(1):78-91.
11. ALGORHYTM
Markey KA, Mollan SP, Jensen RH, Sinclair AJ. Understanding idiopathic intracranial hypertension:
mechanisms, management, and future directions. The Lancet Neurology. 2016 Jan 1;15(1):78-91.
12. PROGNOSIS
Visual prognosis generally good, but permanent in some male patients, early-onset reduced visual
acuity, and black ethnic origin
Headache predominant long-term disability
High-grade papilloedema poor prognostic factor
Early age of onset and high diagnostic ICP were associated with a good prognosis after 1 year. High ICP
might be associated with a shorter diagnostic latency and early treatment initiation
Markey KA, Mollan SP, Jensen RH, Sinclair AJ. Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. The Lancet Neurology. 2016 Jan 1;15(1):78-91.
13. SUMMARY
Elevated ICP, papilloedema, obese young women
Headache and visual lose
Management: weight loss, acetazolamide, surgery
Bariatric surgery?