Wax it-overview-resin

customized solutions for your research

Our Focus
We are a preclinical histopathology CRO specialized in resin
histopathology for medical devices that are either fully implanted or
partially inserted into the body. We also offer general histology and
immunohistochemistry services (GLP and non-GLP).

202 - 2386 East Mall | Vancouver, BC Canada V6T 1Z3 | info@waxitinc.com | 604.822.1595 | www.waxitinc.com


We operate like an extension of your lab.
- Flexible, customized research solutions.
- Reach research milestones faster and more efficiently.
- Consultative approach to adapt to differing project needs.
- Save on infrastructure: access experts when you need them.



Resin Histology: Medical Device & Bone
- Soft and hard tissues, implanted medical devices, and bone.
- Custom protocols.
- Imaging and data analysis.
- Work with a variety of resins to best match the material/device:
- Methyl Methacrylate (MMA)
- Glycol Methacrylate (GMA)
- Spurr's Epoxy



Sample Devices
- Stents
- Artificial muscle
- Heart valves
- Silk and artificial fibres
- Bio-absorptive materials
- Sutures
- Polymers



Imaging & Analysis
- Digital microscopy imaging.
- Digital whole slide scanning: high-resolution imaging
permits real-time zoom for regions of interest.
- Staining quantification: semi-automated IHC quantification permits
data acquisition of area scored, total positive pixels, average positive
pixels, total staining intensity, and average staining intensity, all of
which are separated amongst weakly and strongly stained.



Imaging & Analysis
- Pathological scoring/analysis: our Pathologists work with you to
determine an appropriate scoring criteria.
- Report generation: quantified data can be collated into a
presentation-ready report or PowerPoint presentation, while images
can be professionally edited for publication-ready submission.



Our Pathologists
- U.S. board certified Pathologists with 35 + years experience in
Veterinary Pathology and Toxicologic Pathology.
- Experienced in Pathology reporting for NDA filing.
- Pathological scoring/analysis: our Pathologists work with you to
determine an appropriate scoring criteria.
- Report generation: quantified data can be collated into a
presentation-ready report or PowerPoint presentation, while images
can be professionally edited for publication-ready submission.



General Histology (Discovery, Preclinical, GLP)
- Paraffin and frozen services - grossing, processing, embedding,
sectioning , and slide staining (H&E and special stains).
- GLP histopathology for preclinical toxicology studies.
- Full Pathology reporting (GLP and non GLP).
- Digital microscopy imaging, digital whole slide scanning, staining
quantification, Pathological scoring/analysis, report generation.



Immunohistochemistry Expertise
- Background literature research and sourcing of optimal antibodies
- Antibody optimization
- Cross-reactivity studies
- Protocol development
- Routine IHC staining (manual and automated)
- Slide analysis: digital microscopy imaging, digital whole
slide scanning, staining quantification, Pathological scoring/analysis,
and report generation.



In-House Tissue Bank
- Collection of tissues from multiple species including mouse, rat, pig,
rabbit, and monkey.
- Identify proteins of interest in multiple tissues on a single slide for a
truly macroscopic view of protein distribution, and a complete
antibody cross-reactivity profile.



Get in Touch
Website: www.waxitinc.com | Phone: 604.822.1595
Tanya troberts@waxitinc.com | Aruna asomasiri@waxitinc.com


Wax it-overview-resin

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