Molecular biology and the hopes for the future.

1. Eye color

2. Different colors

3. Brown

4. Blue

5. Grey

6. Green

7. Blue-green?

8. Blue

9. Green

10. Blue

11. Brown?

13. Grey-blue?

15. Browny-green (Hazel)

16. Grey with a little brown

17. Blue – or grey?

18. Looks grey – is it real?

19. Obviously NOT real

20. Who cares, anyway?

21. How about these guys?

22. Neanderthal man

23. What color were their eyes?

24. Who knows?

25. Who cares?

26. How can we find out?

27. DNA samples?

28. Remember Jurassic Park?

29. Fossilized mosquito!!

30. Take out some blood

31. Whose blood?

32. The blood of a neanderthal man!!

33. Get a DNA sample

34. Bring back lost people

35. No … I don’t want to come back!!

36. I don’t like modern humans

37. OK … different animals

38. Bring these back

39. Great idea

40. We can do it!

41. We have the cloning technology

42. Really?

43. We really have the cloning
technology?

44. No, not really!

45. Don’t be stupid.

46. It’s just a movie!

47. But scientists CAN analyze DNA

48. That’s kind of clever

49. For example?

50. Get DNA from bones

51. Figure out eye color

52. Figure out eye color?

53. Yes

54. Not cloning dinosaurs?

55. No

56. Who is going to study that?!

57. Molecular biologists

58. Exciting!

59. Eye color and DNA

60. We can predict eye color!

61. Kind of …

62. To a certain extent

63. Predict eye color?!

64. Parents’ eyes, children’s eyes

65. Two brown eyed parents
• 75% chance brown
• 19% chance blue
• 7% chance green

66. One brown one blue
• 50% chance brown
• 50% chance blue
• 0% chance green

67. That’s SO exciting!

68. Who needs this?

69. We can predict EYE COLOR!!!!

71. Actually, some people care

72. Forensic scientists

73. Computer forensics

74. Forensic molecular biology

75. Forensic science

76. Elementary, my dear Watson

77. Actually, it’s NOT elementary

78. It’s very complicated

79. Analysing DNA to solve crimes

80. DNA swab test

81. Maybe you commit a crime

82. We get a sample of your DNA

83. You are the criminal

84. I am Poirot

85. I don’t need DNA

86. I am a fictional detective

87. How do they do it?

88. Study molecular biology

89. Chromosome

90. Long strand of DNA

91. DNA consists of many genes

92. Genes carry code

93. Eye color, blood type, etc

94. Genes are segments of DNA

95. Certain genes determine eye color

96. • Eight genes for eye color
• Two are the strongest predictors
• But they ALL have an influence

97. Forensic science

98. Must be very accurate

99. Must be VERY careful

100. Modern forensic scientists …

101. … use computers

102. Computer models of genetic variation

103. NOT like this!

104. DNA samples

105. Eye color data

106. From 6,000 people

107. Information into the computer

108. Great!

109. I’m a forensic molecular biologist

110. Call me FMB

111. Give me your DNA sample!

112. Give it to me!!

113. OK, here it is!

114. Here’s my DNA sample

115. OK, I’ve analyzed your DNA sample

116. I used my fantastic computer model!

117. Now I will predict your eye color!!

118. Using my fantastic computer model!

119. Why don’t you just look at my eyes?

120. Shut up!

121. I will use my great computer model

122. OK, I’ve finished.

123. Your eyes are blue

124. No, they are brown

125. Never mind. Only 90% accuracy for
blue and brown

126. Why didn’t you just look at my eyes?

127. Shut up! This is forensic science

128. 90% accuracy for blue and brown

129. 70% for other colors

130. The future is bright

131. We can predict everything!

132. Your hair is red!

133. Your designer baby’s hair will be blue

134. Wait … designer babies?

135. Is that a good idea?

136. Should we be able to decide
EVERYTHING?

137. Even change things about our babies?

138. Change a baby’s DNA?

139. Should scientists really be involved in
this?

140. Can we trust scientists?

141. Is it natural?

142. What if you gave a DNA sample …

143. … then three weeks later …

144. … the police come to your door …

145. … and say, we compared your DNA …

146. … with DNA at a murder scene.

147. You are a murderer!

148. You are a murderer!

149. You are a murderer!

150. My computer model says so!

151. Now let me make a T Rex