![A 29 YO female complains of restlessness and increasing anxiety. HR 135 bmp, PE: Tremors. Palpation on the neck reveals a 3cm nodule on her thyroid gland. Laboratory test are sent to confirm the diagnosis. In the meantime, with drug could be given to acutely reduce her physical symptoms? ,[object Object],[object Object],[object Object],[object Object],[object Object],DR. UMA K.](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
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- 1. DR. UMA K. Thyroid Hormones & Drugs BY DR.UMA KADAM M.B.B.S. MD ASSOCIATE PROFESSOR PHARMACOLOGY SKNMC
- 5. Hormones of Special Interest to Women Thyroxine (T4) Thyronine (T3) Progesterone Estrogen
- 6. DR. UMA K.
- 7. Thyroid Disease The “Hidden” Health Problem DR. UMA K.
- 8. Who do you know with thyroid disease? DR. UMA K.
- 11. Synthesis & release of thyroid hormones: DR. UMA K.
- 13. DR. UMA K.
- 14. Regulation of thyroid hormones: (Negative Feedback Loop) DR. UMA K.
- 16. DR. UMA K. Thyroid hormones: Mechanism of action
- 18. Thyroid Hormone Affects Many Organs and General Health DR. UMA K. Thyroid Uterus Heart Liver Kidney Brain Skin GI Tract Lungs Eyes
- 22. Thyroid drugs DR. UMA K.
- 25. Hypothyroidism: The Hidden Health Problem Affects Up to 25 Million People But Approximately 12 Million Are Undiagnosed
- 26. Hypothyroidism Affects Multiple Body Systems Central Nervous System Female Reproductive System Cardiovascular System Hypothyroidism Can Cause Serious Harm to Your Health
- 27. Signs and Symptoms of Hypothyroidism DR. UMA K. Tiredness Forgetfulness/Slower Thinking Moodiness/ Irritability Depression Inability to Concentrate Thinning Hair or Hair Loss Loss of Body Hair Dry, Patchy Skin Weight Gain Cold Intolerance Elevated Cholesterol Muscle Weakness or Cramps Constipation Infertility Menstrual Irregularities/ Heavy Period Slower Heartbeat Difficulty Swallowing Persistent Dry or Sore Throat Hoarseness/ Deepening of Voice Swelling (Goiter) Puffy Eyes
- 29. Hypothyroidism: The “Hidden” Disease Cardiovascular: Slow Heartbeat Elevated Cholesterol Aging: Dry, Scaly Skin Sparse or Coarse Hair Gynecological: Irregular Menstruation Infertility Gastrointestinal: Constipation Weight Gain Muscular: Muscle Weakness Stiffness Ear, Nose & Throat: Hoarse Voice Psychiatric: Impaired Concentration Depression Lethargy, Fatigue Blood: Anemia
- 31. DR. UMA K. Hypothyroidism After Before
- 35. Antithyroid Drugs DR. UMA K.
- 37. DR. UMA K. Signs and Symptoms Of Hyperthyroidism Bulging Eyes/Unblinking Stare Menstrual Irregularities or Light Period Excessive Vomiting in Pregnancy First-Trimester Miscarriage Family History of Thyroid Disease or Diabetes Nervousness Irritability Difficulty Sleeping Swelling (Goiter) Frequent Bowel Movements Warm, Moist Palms Hoarseness or Deepening of Voice Difficulty Swallowing Rapid or Irregular Heartbeat Infertility Weight Loss Heat Intolerance Increased Sweating Persistent Sore or Dry Throat
- 39. DR. UMA K. Hyperthyroidism Before After
- 40. If You Have Hyperthyroidism, You’re in Good Company DR. UMA K. Barbara Bush 1984 Pre-treatment Barbara Bush 1991 Post-treatment
- 55. TSH Testing Thyroid “ Sends Telegram” Pituitary T3 & T4 TSH
- 59. DR. UMA K. Thank you Thank you