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Be active against cancer!
Tuesday, 4th of February
2014 (World Cancer Day)
Be Active – Why and How?
Professor Nanette Mutrie
Physical Activity for Health Research Centre
University of Edinburgh
• Physical
inactivity has
reached
‘Pandemic’
proportions
• Interventions
are needed!
• July 2012
"Everything that gets worse when you
grow older gets better when you
exercise."
Regular physical activity
reduces risk of:
• All-cause mortality
• Coronary heart
disease
• High blood
pressure
• Stroke
• Falling
• Metabolic
syndrome
• Type 2 diabetes
• Breast cancer
• Colon cancer
• Depression
Lee et al. , Lancet, July 2012
Strong evidence of the
following benefits for adults:
– Increased cardiorespiratory and
muscular fitness
– Healthier body mass and composition
– Improved bone health
– Increased functional health
– Improved cognitive function
Lee et al. , Lancet, July 2012
How does the risk of inactivity
compare with smoking?
0
1
2
3
4
5
6
7
8
9
10
PAF% deaths caused in millions
smoking
smoking
Lee et al. , Lancet, July 2012
How does the risk of inactivity
compare with smoking?
0
1
2
3
4
5
6
7
8
9
10
PAF% deaths caused in millions
smoking
inactivity
Lee et al. , Lancet, July 2012
Percentage of worldwide
burden of disease caused by
inactivity
0 1 2 3 4 5 6 7 8 9 10
CHD
Breast cancer
Type 2 Diabetes
Colon Cancer
Prem mortality
Percentage
Lee et al. , Lancet, July 2012
Public health guidelines on
Physical Activity
CMOs 2011 ‘start active stay active’
150 mins of moderate activity/week
– or 75 mins vigorous intensity per week
– or combination
Strength exercise at least two days/week
Older adults all of above plus
– balance and co-ordination 2/days/week
Limit sedentary behaviour
Percentage adults achieving Scottish
strategy1 recommendations
[SHeS,2012]
39
37
39 39 38
0
10
20
30
40
50
strategy recommendations [5x30]
2008
2009
2010
2011
2012
1. Let’s make Scotland more active. 2003
Percentage adults achieving Scottish
strategy recommendations and ‘new’
recommendations [SHeS,2012]
0
10
20
30
40
50
60
70
strategy recommendations [5x30] new recommendations [150 mins]
2008
2009
2010
2011
2012
Odds of Metabolic Syndrome in Women –
TV Viewing and Physical Activity
Physical activity time
(hrs/wk)
TV viewing
time
(hrs/wk)
*
*
*
* P < 0.05 vs ref.
Courtesy
Neville Owen
Dunstan et al.
(2005).
Diabetologia
48, 2254-2261.
Independent of level of moderate
to vigourous activity, greater sitting
time was associated with
increased endometrial cancer risk
Physical Activity and Cancer Preventability
estimates (PAF%) (UK) (WCRF, 2013)
Site PAF% accounted for by low
physical activity
Breast 12
Colorectum 12
Endometrium 10
http://www.wcrf.org/cancer_statistics/preventability_estimates/preventability_estimates_food.ph
Low physical activity will also influence obesity and
increased risk for the following cancer sites
Oesphagus Breast
Pancreas Colorectum
Gallbladder Endometrium
Kidney
American Cancer Society Guidelines
on Nutrition and Physical Activity for
Cancer Prevention 2012
Physical activity may reduce the risk of
several types of cancer, including cancers of
the breast, colon, and endo- metrium, as
well as advanced prostate cancer, and
possibly, pancreatic cancer.
American Cancer Society Guidelines
on Nutrition and Physical Activity for
Cancer Prevention 2012
• Physical activity may help to prevent
certain cancers via:
• regulating sex hormones
• insulin
• prostaglandins
• various beneficial effects on the immune
system.
Be Active – Why and How?
The HOW part
The ABC of Physical Activity for Health:
A consensus statement from the
British Association of Sport and Exercise Sciences
BASES Journal of Sport Sciences 2010
• A- all adults; B- beginners; C-conditioned
• Beginners
– Something is better than nothing
– Set achievable goals
– Find enjoyment
– Seek support
7 Investments that
work for physical activity
1. ‘Whole-of-school’ programs
2. Transport policies and
systems that prioritise walking,
cycling and public transport
3. Urban design regulations and
infrastructure that provides for
equitable and safe access for
recreational physical activity,
and recreational and transport-
related walking and cycling
across the life course
4. Physical activity and NCD
prevention integrated into
primary health care systems
5. Public education, including
mass media to raise
awareness and change social
norms on physical activity
6. Community-wide programs
involving multiple settings and
sectors & that mobilize and
integrate community
engagement and resources
7. Sports systems and programs
that promote ‘sport for all’
and encourage participation
across the life span
For almost everyone the best place
to start is to increase walking
1) Walking is the easiest mode of activity
for inactive people :
 to get started with
 to sustain
1) Confers all the major benefits of
activity
Why Walking for Health?
Social
Least affected by SIMD
Low to no expenseTRANSFORMATIVE
Habit/
routine
Non age dependent
1st pathway for the least active/sedentary
WHY?
Walking + pedometers?
• Pedometers have been identified as the
single most effective method of physical
activity promotion (Heath et al., 2012).
Understanding behaviour change
techniques [BCTs] in relation to walking
and cycling
• From studies with sig. intervention effects
(n=21) the most frequently coded BCTs were:
– “Prompt self-monitoring of behavior”
– “Prompt intention formation”
• In terms of walking
– the pedometer offers a perfect tool
• Bird EL, Baker G, Mutrie N, Ogilvie D, Sahlqvist S, Powell J. Behavior Change
Techniques Used to Promote Walking and Cycling: A Systematic Review. Health
Psychol. 2013 Mar 11. PubMed PMID: 23477577.
Pedometers make use of several
behaviour change techniques:
goal-setting (individuals can set daily step goals)
self-monitoring (check out daily steps)
self-efficacy (improve confidence in walking
ability)
problem-solving (adapt walking behaviour to suit
weather and setting)
motivation (provide instant feedback to
individuals on goals)
social support (a visual prompt for friends and
family)
• Week 1 and 2:
– an additional 1,500 steps at least 3 days/week
• Week 3 and 4:
– increase to 5 days/week
• Week 5 and 6:
– an additional 3,000 steps on at least 3
days/week
• Week 7:
– increase to 5 days/week
• Week 8-12:
– maintain week 7
WWW
Walking Goals
12-week Results
step-counts
0
2000
4000
6000
8000
10000
Baseline Week 12
Time-point
Mean daily step-counts
Intervention Control
Steps/day
• 65% of intervention group achieved an increase of 15,000 steps/week
154 steps/day
*3,175 steps/day
• * indicates significant difference between baseline and week 12 at p < .001
Step counts
0
2000
4000
6000
8000
10000
12000
baseline 12 weeks 24 weeks 48 weeks
Time point
Steps
MAX
MIN
Cost effectiveness
• Shaw, et al. (2011).
'Pedometers cost
buttons': Bmc Public
Health, 11(1), 200.
• Under £100/person
to achieve
recommended levels
of PA
Find out more:
www.pathsforall.org.uk
Find a Health Walk near you:
www.pathsforall.org.uk/findahealthwalk
Community Pedometer Pack
Paths for All
Strength & Balance Programme
10 simple exercises that will improve strength and balance and reduce the risk
of falls in older adults

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Be Active - Why and How | Professor Nanette Mutrie

  • 1. Be active against cancer! Tuesday, 4th of February 2014 (World Cancer Day) Be Active – Why and How? Professor Nanette Mutrie Physical Activity for Health Research Centre University of Edinburgh
  • 3. "Everything that gets worse when you grow older gets better when you exercise."
  • 4. Regular physical activity reduces risk of: • All-cause mortality • Coronary heart disease • High blood pressure • Stroke • Falling • Metabolic syndrome • Type 2 diabetes • Breast cancer • Colon cancer • Depression Lee et al. , Lancet, July 2012
  • 5. Strong evidence of the following benefits for adults: – Increased cardiorespiratory and muscular fitness – Healthier body mass and composition – Improved bone health – Increased functional health – Improved cognitive function Lee et al. , Lancet, July 2012
  • 6. How does the risk of inactivity compare with smoking? 0 1 2 3 4 5 6 7 8 9 10 PAF% deaths caused in millions smoking smoking Lee et al. , Lancet, July 2012
  • 7. How does the risk of inactivity compare with smoking? 0 1 2 3 4 5 6 7 8 9 10 PAF% deaths caused in millions smoking inactivity Lee et al. , Lancet, July 2012
  • 8. Percentage of worldwide burden of disease caused by inactivity 0 1 2 3 4 5 6 7 8 9 10 CHD Breast cancer Type 2 Diabetes Colon Cancer Prem mortality Percentage Lee et al. , Lancet, July 2012
  • 9.
  • 10. Public health guidelines on Physical Activity CMOs 2011 ‘start active stay active’ 150 mins of moderate activity/week – or 75 mins vigorous intensity per week – or combination Strength exercise at least two days/week Older adults all of above plus – balance and co-ordination 2/days/week Limit sedentary behaviour
  • 11. Percentage adults achieving Scottish strategy1 recommendations [SHeS,2012] 39 37 39 39 38 0 10 20 30 40 50 strategy recommendations [5x30] 2008 2009 2010 2011 2012 1. Let’s make Scotland more active. 2003
  • 12. Percentage adults achieving Scottish strategy recommendations and ‘new’ recommendations [SHeS,2012] 0 10 20 30 40 50 60 70 strategy recommendations [5x30] new recommendations [150 mins] 2008 2009 2010 2011 2012
  • 13. Odds of Metabolic Syndrome in Women – TV Viewing and Physical Activity Physical activity time (hrs/wk) TV viewing time (hrs/wk) * * * * P < 0.05 vs ref. Courtesy Neville Owen Dunstan et al. (2005). Diabetologia 48, 2254-2261.
  • 14. Independent of level of moderate to vigourous activity, greater sitting time was associated with increased endometrial cancer risk
  • 15.
  • 16. Physical Activity and Cancer Preventability estimates (PAF%) (UK) (WCRF, 2013) Site PAF% accounted for by low physical activity Breast 12 Colorectum 12 Endometrium 10 http://www.wcrf.org/cancer_statistics/preventability_estimates/preventability_estimates_food.ph Low physical activity will also influence obesity and increased risk for the following cancer sites Oesphagus Breast Pancreas Colorectum Gallbladder Endometrium Kidney
  • 17. American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention 2012 Physical activity may reduce the risk of several types of cancer, including cancers of the breast, colon, and endo- metrium, as well as advanced prostate cancer, and possibly, pancreatic cancer.
  • 18. American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention 2012 • Physical activity may help to prevent certain cancers via: • regulating sex hormones • insulin • prostaglandins • various beneficial effects on the immune system.
  • 19. Be Active – Why and How? The HOW part
  • 20. The ABC of Physical Activity for Health: A consensus statement from the British Association of Sport and Exercise Sciences BASES Journal of Sport Sciences 2010 • A- all adults; B- beginners; C-conditioned • Beginners – Something is better than nothing – Set achievable goals – Find enjoyment – Seek support
  • 21. 7 Investments that work for physical activity 1. ‘Whole-of-school’ programs 2. Transport policies and systems that prioritise walking, cycling and public transport 3. Urban design regulations and infrastructure that provides for equitable and safe access for recreational physical activity, and recreational and transport- related walking and cycling across the life course 4. Physical activity and NCD prevention integrated into primary health care systems 5. Public education, including mass media to raise awareness and change social norms on physical activity 6. Community-wide programs involving multiple settings and sectors & that mobilize and integrate community engagement and resources 7. Sports systems and programs that promote ‘sport for all’ and encourage participation across the life span
  • 22. For almost everyone the best place to start is to increase walking 1) Walking is the easiest mode of activity for inactive people :  to get started with  to sustain 1) Confers all the major benefits of activity
  • 23.
  • 24. Why Walking for Health? Social Least affected by SIMD Low to no expenseTRANSFORMATIVE Habit/ routine Non age dependent 1st pathway for the least active/sedentary WHY?
  • 25. Walking + pedometers? • Pedometers have been identified as the single most effective method of physical activity promotion (Heath et al., 2012).
  • 26. Understanding behaviour change techniques [BCTs] in relation to walking and cycling • From studies with sig. intervention effects (n=21) the most frequently coded BCTs were: – “Prompt self-monitoring of behavior” – “Prompt intention formation” • In terms of walking – the pedometer offers a perfect tool • Bird EL, Baker G, Mutrie N, Ogilvie D, Sahlqvist S, Powell J. Behavior Change Techniques Used to Promote Walking and Cycling: A Systematic Review. Health Psychol. 2013 Mar 11. PubMed PMID: 23477577.
  • 27. Pedometers make use of several behaviour change techniques: goal-setting (individuals can set daily step goals) self-monitoring (check out daily steps) self-efficacy (improve confidence in walking ability) problem-solving (adapt walking behaviour to suit weather and setting) motivation (provide instant feedback to individuals on goals) social support (a visual prompt for friends and family)
  • 28. • Week 1 and 2: – an additional 1,500 steps at least 3 days/week • Week 3 and 4: – increase to 5 days/week • Week 5 and 6: – an additional 3,000 steps on at least 3 days/week • Week 7: – increase to 5 days/week • Week 8-12: – maintain week 7 WWW Walking Goals
  • 29. 12-week Results step-counts 0 2000 4000 6000 8000 10000 Baseline Week 12 Time-point Mean daily step-counts Intervention Control Steps/day • 65% of intervention group achieved an increase of 15,000 steps/week 154 steps/day *3,175 steps/day • * indicates significant difference between baseline and week 12 at p < .001
  • 30. Step counts 0 2000 4000 6000 8000 10000 12000 baseline 12 weeks 24 weeks 48 weeks Time point Steps MAX MIN
  • 31. Cost effectiveness • Shaw, et al. (2011). 'Pedometers cost buttons': Bmc Public Health, 11(1), 200. • Under £100/person to achieve recommended levels of PA
  • 32. Find out more: www.pathsforall.org.uk Find a Health Walk near you: www.pathsforall.org.uk/findahealthwalk
  • 34. Paths for All Strength & Balance Programme 10 simple exercises that will improve strength and balance and reduce the risk of falls in older adults