The competitive landscape of hemophilia A and B recombinant therapy in the US and 5EU is dominated by the use of recombinant FVIII and FIX replacement factors, and patients with severe forms of the disease receive frequent prophylactic infusions beginning from the first one or two years of life and often continuing through adulthood.

1. Eloctate (Hemophilia A and B) – Forecast and Market Analysis to 2022
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2. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
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The competitive landscape of hemophilia A and B recombinant therapy in the US
and 5EU is dominated by the use of recombinant FVIII and FIX replacement
factors, and patients with severe forms of the disease receive frequent
prophylactic infusions beginning from the first one or two years of life and often
continuing through adulthood. However, the burden on patients and their
families to maintain the prophylactic treatment schedule is high, and there is a
significant unmet need for new therapies that can reduce the number of weekly
prophylactic infusions and alleviate some of this treatment burden.
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http://www.rnrmarketresearch.com/contacts/purchase?rname=145258 .
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3. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
Biogen Idec’s long-lasting recombinant Factor VIII candidate Eloctate is under
FDA regulatory review for prophylactic and on-demand treatment for
hemophilia A patients. Eloctate aims to change the treatment paradigm by
allowing patients to adopt a prophylactic dosing schedule with increased time
between infusions.
Scope
Overview of Hemophilia A and B, including epidemiology, etiology, symptoms,
diagnosis, pathology and treatment guidelines as well as an overview on the
competitive landscape.
Detailed information on Eloctate including product description, safety and
efficacy profiles as well as a SWOT analysis.
Sales forecast for Eloctate for the top nine countries from 2012 to 2022.
Sales information covered for the US, France, Germany, Italy, Spain, the UK,
Japan, Argentina and China.
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4. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
Reasons to buy
Understand and capitalize by identifying products that are most likely to ensure
a robust return
Stay ahead of the competition by understanding the changing competitive
landscape for Hemophilia A and B
Effectively plan your M&A and partnership strategies by identifying drugs with
the most promising sales potential
Make more informed business decisions from insightful and in-depth analysis of
Eloctate performance
Obtain sales forecast for Eloctate from 2012-2022 in top nine countries (the US,
France, Germany, Italy, Spain, the UK, Japan, Argentina and China)
Complete report spread across 59 pages available @
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5. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
Read more on “Eloctate (Hemophilia A and B) – Forecast and Market Analysis to 2022”
report below.
Table of Contents
1 Table of Contents 4
1.1 List of Tables 7
1.2 List of Figures 7
2 Introduction 8
2.1 Catalyst 8
2.2 Related Reports 9
2.3 Upcoming Related Reports 11
3 Disease Overview 12
3.1 Etiology and Pathophysiology 12
3.1.1 Etiology 12
3.1.2 Pathophysiology 13
3.1.3 Prognosis and Quality of Life 15
3.2 Symptoms 16
3.2.1 Hemophilia A and B 16
3.2.2 Inhibitors 17
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6. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
4 Disease Management 18
4.1 Treatment Overview 18
4.1.1 Hemophilia A and B Diagnosis 19
4.1.2 Hemophilia A and B Treatment 19
4.1.3 Inhibitors Diagnosis 21
4.1.4 Inhibitors Treatment 21
5 Competitive Assessment 23
5.1 Overview 23
5.2 Strategic Competitive Assessment 24
6 Opportunity and Unmet Need 28
6.1 Overview 28
6.2 Opportunities Analysis 29
6.2.1 Longer-Lasting Recombinant Factors to Reduce the Frequency of Prophylactic
Injections 29
6.2.2 Lower-Cost Recombinant Replacement Therapies 30
6.2.3 Lower Risk of Inhibitor Formation in Previously Untreated Patients 31
6.2.4 More Convenient Drug Administration 31
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7. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
6.2.5 Oral Formulation of Recombinant Replacement Therapies 32
6.3 Unmet Needs Gap Analysis 32
6.3.1 Long-Acting FVIII Replacement Therapies 32
6.3.2 Gene Therapy Treatments for Hemophilia A and B 33
7 Pipeline Assessment 34
7.1 Overview 34
7.2 Promising Drugs in Clinical Development - Hemophilia A 34
7.3 Promising Drugs in Clinical Development - Hemophilia B 36
7.4 Promising Drugs in Clinical Development - Hemophilia A and B Patients with Inhibitors
38
8 Eloctate (rFVIII-Fc) 39
8.1 Overview 39
8.2 Efficacy 40
8.3 Safety 41
8.4 Dosing and Formulation 41
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8. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
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9. Eloctate (Hemophilia A and B) – Forecast and
Market Analysis to 2022
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