The document summarizes the virus replication cycle. It occurs in living host cells and involves several key steps: 1) Attachment and entry of the virus into the host cell. 2) Uncoating of the viral genome from the protein shell. 3) Synthesis of viral mRNA and proteins using the host cell machinery. 4) Replication of the viral genome. 5) Assembly of new viral particles. 6) Release of progeny viruses through cell lysis or budding, which is how enveloped viruses acquire their lipid envelope. The cycle can take 6-40 hours depending on the virus.

1. VIRUS MULTIPLICATION CYCLE ELIZABETH P. QUILES, M.D., FPASMAP DEPARTMENT OF MICROBIOLOGY OUR LADY OF FATIMA UNIVERSITY COLLEGE OF MEDICINE

22. HLTV HIV No Transcrip- tion Yes + SS diploid Reovirus No Transcrip- tion Yes +/- DS segmented Influenza No Transcrip- tion Yes - segmented Measles Rabies No Transcrip- tion Yes - Nonseg- mented SS Poliovirus Yes Genome No + SS, non segmented Prototype Infectivity Of Genome Source Of mRNA Virion Polyme- rase Polarity RNA Genome

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