Picornaviruses

Picornaviruses Eva L. Dizon M.D.,F.P.P.S

Objectives ,[object Object],[object Object],[object Object],[object Object]

Picornavirus ,[object Object],[object Object],[object Object]

Classification + sense RNA viruses Porcine teschovirus Teschovirus Aichivirus Kobuvirus Equine rhinitis B virus Erbovirus Human parechovirus Parechovirus Hand foot and mouth virus O Aphtovirus Encephalomyocarditis virus Cardiovirus Human Rhinovirus Rhinovirus Hepatitis A Hepatoviruses Poliovirus, Enterovirus, Coxsackie,Echovirus Enteroviruses Picornaviridae Species Genus Family

Genome ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Receptors Adhesion Molecule VCAM Vascular cell adhesion molecule 1 EMCV Immunoglobulin like CD 155 3 Poliovirus Regulator of complement activator Decay accelarating factor (DAF) ,CD55 6 Echovirus Integrin like VLA -2 2 Echovirus ICAM 1 3 Coxsackie A Low density lipoprotein receptor (LDLR) 10 Human rhinovirus Immunoglobulin like ICAM 1,CD 54 91 Human rhinovirus Description Receptors # of Serotypes Virus

Replication ,[object Object],[object Object]

Translation ,[object Object],[object Object]

Time after infection ,[object Object]

Enteroviruses ,[object Object]

Transmission Human Fecal Matter Hand Sewage Solid waste landfills Water supply Shellfish

Transmission ,[object Object],[object Object],[object Object]

Poliovirus ,[object Object],[object Object],[object Object]

Polio ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Coxsackie ,[object Object],[object Object],[object Object],[object Object]

Enteroviruses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Laboratory diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

'New' Enteroviruses: ,[object Object],[object Object]

Treatment and prevention ,[object Object],[object Object],[object Object],[object Object],[object Object]

Rhinovirus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Picornaviruses

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Picornaviruses