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[object Object],Other gram-negative bacilli
VIBRIOS ,[object Object],[object Object],[object Object],[object Object],[object Object]
Vibrio cholerae ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vibrio cholerae ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vibrio cholerae
Vibrio cholerae Cholera Toxin B subunit A subunit Binds GM1 ganglioside (surface of epithelial cells) Carried to ER (retrograde transport) Endocytosis  Reduced by protein disulfide isomerase in ER Cytosol  Unfolding  Refolding  Interact with cytosolic ADP ribosylation factors Activate G protein Stimulate adenylate cyclase Inc. cAMP Open CFTR Cl released in lumen; secretion of HCO 3  , Na +  & water
Vibrio cholerae ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vibrio cholerae ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Growth on TCBS agar plate
Vibrio parahaemolyticus ,[object Object],[object Object],[object Object],[object Object]
 
Vibrio vulnificus ,[object Object],[object Object],[object Object],[object Object]
 
Pseudomonas aeruginosa ,[object Object],[object Object],[object Object],[object Object]
Pseudomonas aeruginosa ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pseudomonas aeruginosa ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pseudomonas aeruginosa ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Ecthyma gangrenosum
 
Osteochondritis of foot
 
Pseudomonas aeruginosa ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Production of pyocyanin, water-soluble green pigment of Pseudomonas aeruginosa. (left tube)
Campylobacter jejuni ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Campylobacter jejuni ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Campylobacter jejuni ,[object Object],[object Object],[object Object],[object Object]
Helicobacter pylori ,[object Object],[object Object],[object Object]
 
 
 
 
Helicobacter pylori ,[object Object],[object Object],[object Object],[object Object]
Helicobacter pylori ,[object Object],[object Object],[object Object]
 
 
Helicobacter pylori ,[object Object],[object Object],[object Object],[object Object]

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