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Anesthesia 3
- 1. ANESTHESIA Claro M. Isidro md
- 10. GENERAL ANESTHETICS: SOLUBILITY Partition Coefficient Blood:Gas Brain:Blood Soluble Methoxyflurane 12 2 Intermediate Halothane 2.4 1.9 Enflurane 1.9 1.5 Isoflurane 1.4 1.6 Poorly soluble Nitrous Oxide 0.46 1.1 Desflurane 0.42 1.3 Sevoflurane 0.59 1.7
Notas do Editor
- The concentration of inhaled anesthetic in the inspired gas has a direct effect on both the maximum tension that can be achieved in the alveoli and rate of increase of its tension in the arterial blood. Increasing the anesthetic concentration in the inspired gases will speed up the rate of induction of anesthesia by increasing the delivery of anesthetic into the alveoli that will result to a rapid rise in alveolar tension of anesthetic. This rapid rise in tension of anestheic in the alveolus will promote the transfer of anesthetic from alveoli to blood resulting to increase in arterial or blood tension or concentration of anesthetic. So that the tension or concentration of anesthetic in the blood approaches that of the inspired gas mixture.
- The concentration of inhaled anesthetic in the inspired gas has a direct effect on both the maximum tension that can be achieved in the alveoli and rate of increase of its tension in the arterial blood. Increasing the anesthetic concentration in the inspired gases will speed up the rate of induction of anesthesia by increasing the delivery of anesthetic into the alveoli that will result to a rapid rise in alveolar tension of anesthetic. This rapid rise in tension of anestheic in the alveolus will promote the transfer of anesthetic from alveoli to blood resulting to increase in arterial or blood tension or concentration of anesthetic. So that the tension or concentration of anesthetic in the blood approaches that of the inspired gas mixture.
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