SlideShare uma empresa Scribd logo
1 de 39
General description of infectious diseases  with fecal-oral  mechanism of trans mission . Typhoid  fever . Paratyphoid A and  B . Sorokhan MD, PhD Bukovinian State Medical University Department of the infection diseases and epidemiology
TYPHOID FEVER   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Etiology ,[object Object],Salmonella typhi organism
Etiology ,[object Object],Salmonella typhi organism
Etiology ,[object Object],Salmonella typhi organism
Epidemiology ,[object Object]
Epidemiology ,[object Object]
Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pathophysiology ,[object Object]
Pathophysiology ,[object Object],[object Object]
Pathology ,[object Object],After initially being ingested in contaminated food such as shellfish, or water, the Salmonella typhi bacteria migrate through the intestinal mucosa of the terminal ileum into the submucosal lymph nodes.  Provider  CDC/Armed Forces Institute of Pathology.
Pathology ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pathology ,[object Object]
Mortality/Morbidity ,[object Object]
Complaints ,[object Object]
Complaints As bacteremia develops, the incubation period ends. Patients often experience chills, diaphoresis, anorexia, dry cough, a dull frontal headache, and myalgias before the onset of a high fever. About 20-40% of patients present with abdominal pain. The incidence of constipation versus diarrhea varies geographically, perhaps because of local differences in diet or S .  typhi strains or genetic variation.   Unusual modes of onset include isolated severe headaches that may mimic meningitis. S .  typhi infection may cause an acute lobar pneumonia. In the early stages of the disease, rigors are rare unless the person also has malaria. This is not an unusual pairing of diseases. Patients may present with arthritis only, urinary symptoms, severe jaundice, or fever.
Physical exam ,[object Object],[object Object]
Physical exam ,[object Object],Rose spots
Physical exam Rose spots on the chest of a patient with typhoid   fever due to the bacterium  Salmonella  typhi . Rose spots constitute a subtle, extremely sparse (often <5 spots), salmon-colored, blanching, truncal, maculopapular rash with 1- to 4-cm lesions that generally resolve within 2-5 days.
Physical exam ,[object Object]
Physical exam ,[object Object]
Physical exam ,[object Object]
Physical exam ,[object Object]
Physical exam ,[object Object]
Differential diagnoses ,[object Object]
Differential diagnoses ,[object Object]
Workup   ,[object Object],[object Object]
Specific serologic tests : ,[object Object],[object Object]
Other nonspecific laboratory studies : ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Medical Care ,[object Object],[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Corticosteroids   ,[object Object]
Outpatient Care ,[object Object],[object Object]
Prevention ,[object Object],[object Object]
Vaccine ,[object Object],[object Object],[object Object],[object Object]
Vaccine ,[object Object],[object Object],[object Object]
Complications   ,[object Object]
Prognosis ,[object Object]
Thank you for your attention!

Mais conteúdo relacionado

Mais procurados

Amebiasis in children
Amebiasis in childrenAmebiasis in children
Amebiasis in childrenAzad Haleem
 
Pathophysiology of Leptospirosis
Pathophysiology of LeptospirosisPathophysiology of Leptospirosis
Pathophysiology of LeptospirosisAlipate Koroitanoa
 
Pyrexia of unknown origin (PUO)
Pyrexia of unknown origin (PUO)Pyrexia of unknown origin (PUO)
Pyrexia of unknown origin (PUO)yuyuricci
 
CLINICAL FEATURES AND COMPLICATIONS OF MALARIA
CLINICAL FEATURES AND COMPLICATIONS OF MALARIACLINICAL FEATURES AND COMPLICATIONS OF MALARIA
CLINICAL FEATURES AND COMPLICATIONS OF MALARIAAbino David
 
Infective endocarditis
Infective endocarditis Infective endocarditis
Infective endocarditis ikramdr01
 
Acute Poststreptococcal Glomerulonephritis
Acute Poststreptococcal GlomerulonephritisAcute Poststreptococcal Glomerulonephritis
Acute Poststreptococcal GlomerulonephritisHakimah Suhaimi
 
Acute gastroenteritis in children
Acute gastroenteritis in childrenAcute gastroenteritis in children
Acute gastroenteritis in childrengotolamy
 
Enteric fever (typhoid fever)
Enteric fever (typhoid fever)Enteric fever (typhoid fever)
Enteric fever (typhoid fever)yuyuricci
 
Acute gastroenteritis presentation 2018
Acute gastroenteritis presentation 2018Acute gastroenteritis presentation 2018
Acute gastroenteritis presentation 2018Abdulaziz Bagasi
 
NEPHRITIC SYNDROME / APSGN IN CHILDREN
NEPHRITIC SYNDROME / APSGN IN CHILDREN NEPHRITIC SYNDROME / APSGN IN CHILDREN
NEPHRITIC SYNDROME / APSGN IN CHILDREN Sajjad Sabir
 
Acute glomerulonephritis for UGs
Acute glomerulonephritis for UGsAcute glomerulonephritis for UGs
Acute glomerulonephritis for UGsCSN Vittal
 
Rheumatic Heart Disease
 Rheumatic Heart Disease Rheumatic Heart Disease
Rheumatic Heart DiseaseNeelu Aryal
 

Mais procurados (20)

Gastroenteritis Adults
Gastroenteritis AdultsGastroenteritis Adults
Gastroenteritis Adults
 
Amebiasis in children
Amebiasis in childrenAmebiasis in children
Amebiasis in children
 
TYPHOID FEVER
TYPHOID FEVERTYPHOID FEVER
TYPHOID FEVER
 
Pathophysiology of Leptospirosis
Pathophysiology of LeptospirosisPathophysiology of Leptospirosis
Pathophysiology of Leptospirosis
 
Lupus nephritis
Lupus nephritisLupus nephritis
Lupus nephritis
 
Pyrexia of unknown origin (PUO)
Pyrexia of unknown origin (PUO)Pyrexia of unknown origin (PUO)
Pyrexia of unknown origin (PUO)
 
CLINICAL FEATURES AND COMPLICATIONS OF MALARIA
CLINICAL FEATURES AND COMPLICATIONS OF MALARIACLINICAL FEATURES AND COMPLICATIONS OF MALARIA
CLINICAL FEATURES AND COMPLICATIONS OF MALARIA
 
Infective endocarditis
Infective endocarditis Infective endocarditis
Infective endocarditis
 
Giardiasis
GiardiasisGiardiasis
Giardiasis
 
Rheumatic fever
Rheumatic feverRheumatic fever
Rheumatic fever
 
Acute Poststreptococcal Glomerulonephritis
Acute Poststreptococcal GlomerulonephritisAcute Poststreptococcal Glomerulonephritis
Acute Poststreptococcal Glomerulonephritis
 
Acute gastroenteritis in children
Acute gastroenteritis in childrenAcute gastroenteritis in children
Acute gastroenteritis in children
 
Enteric fever (typhoid fever)
Enteric fever (typhoid fever)Enteric fever (typhoid fever)
Enteric fever (typhoid fever)
 
Acute gastroenteritis presentation 2018
Acute gastroenteritis presentation 2018Acute gastroenteritis presentation 2018
Acute gastroenteritis presentation 2018
 
NEPHRITIC SYNDROME / APSGN IN CHILDREN
NEPHRITIC SYNDROME / APSGN IN CHILDREN NEPHRITIC SYNDROME / APSGN IN CHILDREN
NEPHRITIC SYNDROME / APSGN IN CHILDREN
 
Acute glomerulonephritis for UGs
Acute glomerulonephritis for UGsAcute glomerulonephritis for UGs
Acute glomerulonephritis for UGs
 
Pericarditis
PericarditisPericarditis
Pericarditis
 
Enteric fever
Enteric feverEnteric fever
Enteric fever
 
Rheumatic Heart Disease
 Rheumatic Heart Disease Rheumatic Heart Disease
Rheumatic Heart Disease
 
Sickle cell disease
Sickle cell diseaseSickle cell disease
Sickle cell disease
 

Destaque (20)

Typhoid fever ppt
Typhoid fever pptTyphoid fever ppt
Typhoid fever ppt
 
Typhoid Fever
Typhoid FeverTyphoid Fever
Typhoid Fever
 
Typhoid Fever
Typhoid FeverTyphoid Fever
Typhoid Fever
 
Typhoid
TyphoidTyphoid
Typhoid
 
Typhoid Fever
Typhoid FeverTyphoid Fever
Typhoid Fever
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
 
Typhoid
Typhoid Typhoid
Typhoid
 
Typhoid fever
Typhoid fever Typhoid fever
Typhoid fever
 
Typhoid Fever
Typhoid FeverTyphoid Fever
Typhoid Fever
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
 
Transparencies and slides identification points
Transparencies and slides identification pointsTransparencies and slides identification points
Transparencies and slides identification points
 
Presentation
PresentationPresentation
Presentation
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
 
Sexually Transmitted Infections
Sexually Transmitted InfectionsSexually Transmitted Infections
Sexually Transmitted Infections
 
Enteric fever ug
Enteric fever ugEnteric fever ug
Enteric fever ug
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
 
Ulcerative intestine
Ulcerative  intestineUlcerative  intestine
Ulcerative intestine
 
Dengue
DengueDengue
Dengue
 
Hyperglycemic Crises
Hyperglycemic CrisesHyperglycemic Crises
Hyperglycemic Crises
 

Semelhante a Lecture 5. typhoid fever 3 (20)

Enteric(Typhoid) Fever.pptx
Enteric(Typhoid) Fever.pptxEnteric(Typhoid) Fever.pptx
Enteric(Typhoid) Fever.pptx
 
Enteric fever
Enteric feverEnteric fever
Enteric fever
 
Salmonellosis
SalmonellosisSalmonellosis
Salmonellosis
 
Typhoid
TyphoidTyphoid
Typhoid
 
Enteric fever.pptx
Enteric fever.pptxEnteric fever.pptx
Enteric fever.pptx
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
 
Enteric fever
Enteric feverEnteric fever
Enteric fever
 
Enteric fever
Enteric feverEnteric fever
Enteric fever
 
Enteric fever(typhoid fever)
Enteric fever(typhoid fever)Enteric fever(typhoid fever)
Enteric fever(typhoid fever)
 
ENTERIC FEVER
ENTERIC FEVER ENTERIC FEVER
ENTERIC FEVER
 
Salmonella typhi
Salmonella typhiSalmonella typhi
Salmonella typhi
 
Typhoid fever 1
Typhoid fever 1Typhoid fever 1
Typhoid fever 1
 
TYPHOID FEVER.& Other T. Diseases..pptx
TYPHOID FEVER.& Other T. Diseases..pptxTYPHOID FEVER.& Other T. Diseases..pptx
TYPHOID FEVER.& Other T. Diseases..pptx
 
TYPHOID FEVER.& Other T. Diseases..pptx
TYPHOID FEVER.& Other T. Diseases..pptxTYPHOID FEVER.& Other T. Diseases..pptx
TYPHOID FEVER.& Other T. Diseases..pptx
 
Typhoid_Fever.ppt
Typhoid_Fever.pptTyphoid_Fever.ppt
Typhoid_Fever.ppt
 
Enteric fever in children
Enteric fever in childrenEnteric fever in children
Enteric fever in children
 
Typhoid & c holera zaim
Typhoid & c holera zaimTyphoid & c holera zaim
Typhoid & c holera zaim
 
Enteric fever
Enteric feverEnteric fever
Enteric fever
 
Enumeration of salmonella and shigella
Enumeration of salmonella and shigellaEnumeration of salmonella and shigella
Enumeration of salmonella and shigella
 
Enteric fever
Enteric feverEnteric fever
Enteric fever
 

Mais de Vasyl Sorokhan (20)

Leishmaniasis
LeishmaniasisLeishmaniasis
Leishmaniasis
 
Infectious mononucleosis
Infectious mononucleosisInfectious mononucleosis
Infectious mononucleosis
 
TORCH
TORCHTORCH
TORCH
 
Shigellosis
ShigellosisShigellosis
Shigellosis
 
Botulism
BotulismBotulism
Botulism
 
Lassa fever
Lassa feverLassa fever
Lassa fever
 
Erysipelas
ErysipelasErysipelas
Erysipelas
 
Erysipelas jainish patel
Erysipelas  jainish patelErysipelas  jainish patel
Erysipelas jainish patel
 
Malaria
MalariaMalaria
Malaria
 
Lecture brucellosis 5
Lecture   brucellosis 5Lecture   brucellosis 5
Lecture brucellosis 5
 
Lecture nematodes
Lecture   nematodesLecture   nematodes
Lecture nematodes
 
Lecture 15. hemorrhagic fevers
Lecture 15. hemorrhagic feversLecture 15. hemorrhagic fevers
Lecture 15. hemorrhagic fevers
 
Lecture 14. aids
Lecture 14. aidsLecture 14. aids
Lecture 14. aids
 
Lecture 13.vhbcd
Lecture 13.vhbcdLecture 13.vhbcd
Lecture 13.vhbcd
 
Lecture 12.vha vhe
Lecture 12.vha vheLecture 12.vha vhe
Lecture 12.vha vhe
 
Lecture 11. meningitis
Lecture 11. meningitisLecture 11. meningitis
Lecture 11. meningitis
 
Lecture 10. diphtheria
Lecture 10. diphtheriaLecture 10. diphtheria
Lecture 10. diphtheria
 
Lecture 9. hospital aquired infection
Lecture 9. hospital aquired infectionLecture 9. hospital aquired infection
Lecture 9. hospital aquired infection
 
Lecture 8. anthrex, plague
Lecture 8. anthrex, plagueLecture 8. anthrex, plague
Lecture 8. anthrex, plague
 
Lecture 7. influenza
Lecture 7. influenzaLecture 7. influenza
Lecture 7. influenza
 

Lecture 5. typhoid fever 3

  • 1. General description of infectious diseases with fecal-oral mechanism of trans mission . Typhoid fever . Paratyphoid A and B . Sorokhan MD, PhD Bukovinian State Medical University Department of the infection diseases and epidemiology
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16. Complaints As bacteremia develops, the incubation period ends. Patients often experience chills, diaphoresis, anorexia, dry cough, a dull frontal headache, and myalgias before the onset of a high fever. About 20-40% of patients present with abdominal pain. The incidence of constipation versus diarrhea varies geographically, perhaps because of local differences in diet or S . typhi strains or genetic variation. Unusual modes of onset include isolated severe headaches that may mimic meningitis. S . typhi infection may cause an acute lobar pneumonia. In the early stages of the disease, rigors are rare unless the person also has malaria. This is not an unusual pairing of diseases. Patients may present with arthritis only, urinary symptoms, severe jaundice, or fever.
  • 17.
  • 18.
  • 19. Physical exam Rose spots on the chest of a patient with typhoid fever due to the bacterium Salmonella typhi . Rose spots constitute a subtle, extremely sparse (often <5 spots), salmon-colored, blanching, truncal, maculopapular rash with 1- to 4-cm lesions that generally resolve within 2-5 days.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39. Thank you for your attention!