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Alan Solinsky, MD
David Jeng, MD
1013 Farmington Ave
West Hartford, CT 06107
(860) 233-2020
david.jeng@solinskyeyecare.com
This course provides an overview of how
femtosecond lasers can and will benefit
patients with cataracts and astigmatism.
 To understand the uses of the femtosecond
laser
 To review the features of various systems and
specifically the Alcon LenSx® Laser
 To review the evidence in support of the
functionality of femtosecond lasers
 To recognize the benefit of the femtosecond
laser in cataract surgery
 Neither Alan Solinsky nor David Jeng has direct
financial or proprietary interest in any of the
companies or services mentioned in this
presentation
 Neither Alan Solinsky nor David Jeng has received
commercial support from any of the mentioned
companies
 Alan Solinsky is affiliated with Allergan as a
speaker.
 The content and format of this course may reflect
commercial bias BUT it does not claim superiority
of any commercial product or service
 Earlier diagnosis and treatment before
substantial vision loss
 Baby Boomer patients demanding high quality
post-operative vision
 New surgical approaches and lens implants
available to improve UCVA for many patients
 A laser that emits optical pulses with a
duration in the range of femtoseconds (1 fs =
10-15 seconds)
 Allows for precise cutting of tissue with
minimal collateral damage
 Utilized since 2001 in ophthalmologic
procedures such as LASIK, corneal transplants
 Alcon LenSx® (approved for all steps)
 LensAR® system (approved for all steps)
 OptiMedica Catalys® (approved for all steps)
 B+L Victus® (approved for corneal flaps,
incisions and anterior capsulotomy)
 AMO Intralase® FS (used in LASIK flaps,
approved for arcuate incisions only)
 Liquid Optics™ Interface
 Integral Guidance™
 Attached ergonomic surgical chair
 Augmented Reality™
 Optical ray-tracing (Schleimpflug imaging)
 Lens Tilt detection
 Small footprint and Articulating arm may
allow for positioning in one operating room
 Allows for LASIK flap creation and corneal
incisions
 The LenSx® Laser was the first femtosecond laser
cleared by the FDA for use in cataract surgery. It is
indicated for:
 Anterior capsulotomy
 Lens fragmentation
 All corneal incisions
 The LenSx® Laser brings a new level of precision to
these surgical steps through a number of high-tech
features:
 Real-time video imaging with integrated OCT.
Provides three-dimensional visualization of the entire
anterior segment during docking, planning and
procedure.
 Curved patient interface. Designed for patient
comfort, ease of use and optimal laser performance.
 Intuitive touch screen graphic user interface. Allows
each step of the procedure to be easily planned,
customized and executed.
 True image-guided surgical planning. Enables the
surgeon to precisely program the size, shape and
location of each incision.
 Currently, FDA-approved for 3 steps:
 All corneal incisions
 Anterior capsulotomy
 Lens fragmentation
 But, why is this important?
 Corneal Incisions
 Anterior capsulotomy
 Lens fragmentation
 Offers a new level of precision and
reproducibility in ophthalmic surgery
 Helps to optimize the capsular and corneal
incisions
1. Nagy, ZZ. 1-year clinical experience with a new femtosecond laser for refractive cataract surgery. Paper presented at: Annual
Meeting of the American Academy of Ophthalmology; October 24-27, 2009;
2. Nagy, ZZ. Intraocular femtosecond laser applications in cataract surgery. Cataract & Refractive Surgery Today. September 2009:79-
82. San Francisco, CA.
 LenSx® features an onboard, proprietary optical
coherence tomographer (OCT) in conjunction with
a video microscope, to provide three-dimensional
visualization of the anterior segment. It can
visualize multiple views, including:
 Side View, Capsular Bag
 Topographic View, Lens
 Side View, Cornea
 Catalys also includes integrated OCT
 LensAR uses ray-tracing technology for 3D
visualization
 A disposable, single-use, soft contact lens is used to dock with the
patient's eye.
 This curved patient interface is designed for patient comfort, ease
of use, and optimal laser performance.
 Surgeons guide and gently dock the disposable patient interface
using the video microscope and integrated real-time OCT.
 The unique shape of the patient interface helps maintain a more
natural curvature of the patient's cornea. This helps to improve
surgical accuracy during the LenSx® Laser procedure.
 Both Catalys and LensAR have a low-pressure
fluid-filled docking system
 Corneal Incisions
 Anterior capsulotomy
 Lens fragmentation
 Corneal Incisions
 Primary and Secondary Incisions
 Astigmatism
 Anterior capsulotomy
 Lens fragmentation
 Imprecise tunnel length and geometry
 Frequently require stromal hydration to seal
wound, which induces corneal edema
 Poor wound construction may lead to snowball
effect of intraoperative difficulties (anterior
chamber maintenance and fluid dynamics)
 Incisions may be unstable, which may lead to
increased risk of infection
Behrens A, Stark WJ, Pratzer KA, McDonnell PJ. Dynamics of small-incision clear cornea wounds after
phacoemulsification surgery
using optical coherence tomography in the early postoperative period. J Refract Surg, 2008;24(1):46-9
Taban M, Behrens A. Newcomb RL, et al. Acute endophthalmitis following cataract surgery: a systematic review of
literature. Arch
Ophthalmol. 2005;123(5):613-20
 Primary and secondary incisions (including
arcuate incisions) can be created
 Size and degree of each incision and its
orientation are customizable
Single-plane cut
Two-plane cut
Three-plane cut
 Corneal Incisions
 Primary and Secondary Incisions
 Astigmatism
 Anterior capsulotomy
 Lens fragmentation
 Manually created using
handheld diamond
blade
 Inconsistent depth
control
 Risk of perforating
cornea
 Unpredictable effect
due to imprecise wound
architecture and depth
 No image-guided
planning or
visualization
 Image-guided surgical
planning with OCT
 Real time corneal thickness
 Computer-customized
incisions
 % depth
 Incision length and position
 3D visualization of incision
placement
 Predictable incision width
 Titratable incisions
(adjustable intraoperatively
and post-operatively in
office)
 Corneal Incisions
 Anterior capsulotomy
 Lens fragmentation
 Continuous and perfectly curvilinear
 Potentially stronger with lower likelihood of
anterior capsular tears
 Only 10% of manually created capsulorhexis
achieved a similar diameter accuracy of +/-0.25
mm vs. nearly 100% of LenSx procedures
Nagy, ZZ. 1-year clinical experience with a new femtosecond laser for refractive cataract surgery. Paper presented at:
Annual
Meeting of the American Academy of Ophthalmology; October 24-27, 2009; San Francisco, CA.
Nagy, ZZ. Intraocular femtosecond laser applications in cataract surgery. Cataract & Refractive Surgery Today. September
2009:79-82.
Anterior Capsulotomy
“The key to highly accurate IOL power
calculation is being able to correctly predict
ELP for any given patient and IOL”
Studies show that the size of capsulorhexis affects
ELP
Capsulorhexis needs to be round, centered, and
just smaller than the IOL optic diameter
Haigis W, Lege B, Miller N, Schneider B. Comparison of immersion ultrasound biometry and partial coherence
interferometry for IOL
calculation according to Haigis. Graefes Arch Clin Exp Ophthalmol, 2000;238:765-73
Cekic O, Batman C, The relationship between capsulorhexis size and anterior chamber depth relation. Ophthalmic Surg
Lasers,
1999;30(3):185-90
Hill WE. Hitting Emmetropia. Chang D. (ed) In: Mastering Refractive IOLs – The Art and Science. Slack, Incorporated,
2008
Hill WE. Does the Capsulorhexis Affect Refractive Outcomes? Chang D. (ed) In: Cataract Surgery Today, Bryn Mawr
Communications,
Wayne, Pennsylvania 2009, p.78
 Using the available laser systems, it is possible
to precisely center the capsulorhexis and
determine the diameter and depth of the
anterior capsulotomy.
Manual
Femtosecond Laser
 Non-randomized, prospective, single site, single
surgeon study
 With single lens type, ALCON monofocal SN60WF
 Manual group (n=26)
 Attempted 5.0mm manual capsulotomy
 LenSx Laser group (n=22)
 Femtosecond laser created 5.0mm capsulotomy
 Accuracy to Target, Actual ELP
 No significant difference in baseline between
cohortsRobert J Cionni MD. Presented AAO 2011 Refractive Sub-Specialty Day, “Comparison of Effective Lens Position and Refractive
Outcome:
Femtosecond Laser vs Manual Capsulotomy”
 Corneal Incisions
 Anterior capsulotomy
 Lens fragmentation
 The femtosecond laser performs lens
fragmentation, creating easily dissected
segments for efficient removal with reduced
phaco power.
 Most systems allow the surgeon to set the lens
fragmentation pattern, from pie cuts to
complete liquefaction.
 Patterns can be customized for the cataract
type
 Spares ultrasonic power and time
Ecsedy M, Miháltz K, Kovács I, Takács A, Filkorn T, Nagy ZZ, Effect of Femtosecond
Laser Cataract
Surgery on the Macula, Journal of Refractive Surgery, 2011;27:717-722.
Miháltz K, Knorz MC, Alio JL, Takács A, Kránitz K, Kovács I, Nagy ZZ, Internal
Aberrations and
Optical Quality After Femtosecond Laser Anterior Capsulotomy in Cataract
Surgery, Journal of Refractive Surgery, 2011;27:711-716.
Nagy ZZ, Kránitz K, Takács A, Miháltz K, Kovács I, Knorz MC, Comparison of
Intraocular Lens
Decentration Parameters After Femtosecond and Manual Capsulotomies, Journal
of Refractive Surgery, 2011;27:565-569.
Kránitz K, Takács A, Miháltz K, Kovács I, Knorz MC, Nagy ZZ, Femtosecond Laser
Capsulotomy and
Manual Continuous Curvilinear Capsulorrhexis Parameters and Their Effects on
Intraocular Lens Centration, Journal of Refractive Surgery, 2011;27:559-563.
Nagy ZZ, Takács A, Filkorn T, Sarayba M, Initial Clinical Evaluation of an Intraocular
Femtosecond
Laser in Cataract Surgery, Journal of Refractive Surgery, 2009;25:1053-1060
 Image-guided femtosecond laser designed
specifically for refractive cataract surgery
 Using a customizable 3-D surgical platform, it
allows visualization, customization and
completion of many of the most challenging
steps of cataract surgery:
 Anterior capsulotomy
 Lens fragmentation
 All corneal incisions
Femtosecond laser assistedcataractsurgery

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Femtosecond laser assistedcataractsurgery

  • 1. Alan Solinsky, MD David Jeng, MD 1013 Farmington Ave West Hartford, CT 06107 (860) 233-2020 david.jeng@solinskyeyecare.com
  • 2. This course provides an overview of how femtosecond lasers can and will benefit patients with cataracts and astigmatism.
  • 3.  To understand the uses of the femtosecond laser  To review the features of various systems and specifically the Alcon LenSx® Laser  To review the evidence in support of the functionality of femtosecond lasers  To recognize the benefit of the femtosecond laser in cataract surgery
  • 4.  Neither Alan Solinsky nor David Jeng has direct financial or proprietary interest in any of the companies or services mentioned in this presentation  Neither Alan Solinsky nor David Jeng has received commercial support from any of the mentioned companies  Alan Solinsky is affiliated with Allergan as a speaker.  The content and format of this course may reflect commercial bias BUT it does not claim superiority of any commercial product or service
  • 5.  Earlier diagnosis and treatment before substantial vision loss  Baby Boomer patients demanding high quality post-operative vision  New surgical approaches and lens implants available to improve UCVA for many patients
  • 6.
  • 7.
  • 8.  A laser that emits optical pulses with a duration in the range of femtoseconds (1 fs = 10-15 seconds)  Allows for precise cutting of tissue with minimal collateral damage  Utilized since 2001 in ophthalmologic procedures such as LASIK, corneal transplants
  • 9.  Alcon LenSx® (approved for all steps)  LensAR® system (approved for all steps)  OptiMedica Catalys® (approved for all steps)  B+L Victus® (approved for corneal flaps, incisions and anterior capsulotomy)  AMO Intralase® FS (used in LASIK flaps, approved for arcuate incisions only)
  • 10.
  • 11.
  • 12.  Liquid Optics™ Interface  Integral Guidance™  Attached ergonomic surgical chair
  • 13.
  • 14.  Augmented Reality™  Optical ray-tracing (Schleimpflug imaging)  Lens Tilt detection  Small footprint and Articulating arm may allow for positioning in one operating room
  • 15.
  • 16.  Allows for LASIK flap creation and corneal incisions
  • 17.
  • 18.  The LenSx® Laser was the first femtosecond laser cleared by the FDA for use in cataract surgery. It is indicated for:  Anterior capsulotomy  Lens fragmentation  All corneal incisions  The LenSx® Laser brings a new level of precision to these surgical steps through a number of high-tech features:  Real-time video imaging with integrated OCT. Provides three-dimensional visualization of the entire anterior segment during docking, planning and procedure.  Curved patient interface. Designed for patient comfort, ease of use and optimal laser performance.  Intuitive touch screen graphic user interface. Allows each step of the procedure to be easily planned, customized and executed.  True image-guided surgical planning. Enables the surgeon to precisely program the size, shape and location of each incision.
  • 19.  Currently, FDA-approved for 3 steps:  All corneal incisions  Anterior capsulotomy  Lens fragmentation  But, why is this important?
  • 20.  Corneal Incisions  Anterior capsulotomy  Lens fragmentation
  • 21.
  • 22.
  • 23.  Offers a new level of precision and reproducibility in ophthalmic surgery  Helps to optimize the capsular and corneal incisions 1. Nagy, ZZ. 1-year clinical experience with a new femtosecond laser for refractive cataract surgery. Paper presented at: Annual Meeting of the American Academy of Ophthalmology; October 24-27, 2009; 2. Nagy, ZZ. Intraocular femtosecond laser applications in cataract surgery. Cataract & Refractive Surgery Today. September 2009:79- 82. San Francisco, CA.
  • 24.
  • 25.  LenSx® features an onboard, proprietary optical coherence tomographer (OCT) in conjunction with a video microscope, to provide three-dimensional visualization of the anterior segment. It can visualize multiple views, including:  Side View, Capsular Bag  Topographic View, Lens  Side View, Cornea
  • 26.  Catalys also includes integrated OCT  LensAR uses ray-tracing technology for 3D visualization
  • 27.  A disposable, single-use, soft contact lens is used to dock with the patient's eye.  This curved patient interface is designed for patient comfort, ease of use, and optimal laser performance.  Surgeons guide and gently dock the disposable patient interface using the video microscope and integrated real-time OCT.  The unique shape of the patient interface helps maintain a more natural curvature of the patient's cornea. This helps to improve surgical accuracy during the LenSx® Laser procedure.
  • 28.  Both Catalys and LensAR have a low-pressure fluid-filled docking system
  • 29.  Corneal Incisions  Anterior capsulotomy  Lens fragmentation
  • 30.  Corneal Incisions  Primary and Secondary Incisions  Astigmatism  Anterior capsulotomy  Lens fragmentation
  • 31.  Imprecise tunnel length and geometry  Frequently require stromal hydration to seal wound, which induces corneal edema  Poor wound construction may lead to snowball effect of intraoperative difficulties (anterior chamber maintenance and fluid dynamics)  Incisions may be unstable, which may lead to increased risk of infection Behrens A, Stark WJ, Pratzer KA, McDonnell PJ. Dynamics of small-incision clear cornea wounds after phacoemulsification surgery using optical coherence tomography in the early postoperative period. J Refract Surg, 2008;24(1):46-9 Taban M, Behrens A. Newcomb RL, et al. Acute endophthalmitis following cataract surgery: a systematic review of literature. Arch Ophthalmol. 2005;123(5):613-20
  • 32.
  • 33.  Primary and secondary incisions (including arcuate incisions) can be created  Size and degree of each incision and its orientation are customizable Single-plane cut Two-plane cut Three-plane cut
  • 34.
  • 35.  Corneal Incisions  Primary and Secondary Incisions  Astigmatism  Anterior capsulotomy  Lens fragmentation
  • 36.
  • 37.  Manually created using handheld diamond blade  Inconsistent depth control  Risk of perforating cornea  Unpredictable effect due to imprecise wound architecture and depth  No image-guided planning or visualization
  • 38.  Image-guided surgical planning with OCT  Real time corneal thickness  Computer-customized incisions  % depth  Incision length and position  3D visualization of incision placement  Predictable incision width  Titratable incisions (adjustable intraoperatively and post-operatively in office)
  • 39.
  • 40.  Corneal Incisions  Anterior capsulotomy  Lens fragmentation
  • 41.  Continuous and perfectly curvilinear  Potentially stronger with lower likelihood of anterior capsular tears
  • 42.  Only 10% of manually created capsulorhexis achieved a similar diameter accuracy of +/-0.25 mm vs. nearly 100% of LenSx procedures Nagy, ZZ. 1-year clinical experience with a new femtosecond laser for refractive cataract surgery. Paper presented at: Annual Meeting of the American Academy of Ophthalmology; October 24-27, 2009; San Francisco, CA. Nagy, ZZ. Intraocular femtosecond laser applications in cataract surgery. Cataract & Refractive Surgery Today. September 2009:79-82.
  • 44.
  • 45. “The key to highly accurate IOL power calculation is being able to correctly predict ELP for any given patient and IOL” Studies show that the size of capsulorhexis affects ELP Capsulorhexis needs to be round, centered, and just smaller than the IOL optic diameter Haigis W, Lege B, Miller N, Schneider B. Comparison of immersion ultrasound biometry and partial coherence interferometry for IOL calculation according to Haigis. Graefes Arch Clin Exp Ophthalmol, 2000;238:765-73 Cekic O, Batman C, The relationship between capsulorhexis size and anterior chamber depth relation. Ophthalmic Surg Lasers, 1999;30(3):185-90 Hill WE. Hitting Emmetropia. Chang D. (ed) In: Mastering Refractive IOLs – The Art and Science. Slack, Incorporated, 2008 Hill WE. Does the Capsulorhexis Affect Refractive Outcomes? Chang D. (ed) In: Cataract Surgery Today, Bryn Mawr Communications, Wayne, Pennsylvania 2009, p.78
  • 46.  Using the available laser systems, it is possible to precisely center the capsulorhexis and determine the diameter and depth of the anterior capsulotomy.
  • 48.  Non-randomized, prospective, single site, single surgeon study  With single lens type, ALCON monofocal SN60WF  Manual group (n=26)  Attempted 5.0mm manual capsulotomy  LenSx Laser group (n=22)  Femtosecond laser created 5.0mm capsulotomy  Accuracy to Target, Actual ELP  No significant difference in baseline between cohortsRobert J Cionni MD. Presented AAO 2011 Refractive Sub-Specialty Day, “Comparison of Effective Lens Position and Refractive Outcome: Femtosecond Laser vs Manual Capsulotomy”
  • 49.
  • 50.
  • 51.  Corneal Incisions  Anterior capsulotomy  Lens fragmentation
  • 52.  The femtosecond laser performs lens fragmentation, creating easily dissected segments for efficient removal with reduced phaco power.  Most systems allow the surgeon to set the lens fragmentation pattern, from pie cuts to complete liquefaction.
  • 53.  Patterns can be customized for the cataract type  Spares ultrasonic power and time
  • 54. Ecsedy M, Miháltz K, Kovács I, Takács A, Filkorn T, Nagy ZZ, Effect of Femtosecond Laser Cataract Surgery on the Macula, Journal of Refractive Surgery, 2011;27:717-722. Miháltz K, Knorz MC, Alio JL, Takács A, Kránitz K, Kovács I, Nagy ZZ, Internal Aberrations and Optical Quality After Femtosecond Laser Anterior Capsulotomy in Cataract Surgery, Journal of Refractive Surgery, 2011;27:711-716. Nagy ZZ, Kránitz K, Takács A, Miháltz K, Kovács I, Knorz MC, Comparison of Intraocular Lens Decentration Parameters After Femtosecond and Manual Capsulotomies, Journal of Refractive Surgery, 2011;27:565-569. Kránitz K, Takács A, Miháltz K, Kovács I, Knorz MC, Nagy ZZ, Femtosecond Laser Capsulotomy and Manual Continuous Curvilinear Capsulorrhexis Parameters and Their Effects on Intraocular Lens Centration, Journal of Refractive Surgery, 2011;27:559-563. Nagy ZZ, Takács A, Filkorn T, Sarayba M, Initial Clinical Evaluation of an Intraocular Femtosecond Laser in Cataract Surgery, Journal of Refractive Surgery, 2009;25:1053-1060
  • 55.  Image-guided femtosecond laser designed specifically for refractive cataract surgery  Using a customizable 3-D surgical platform, it allows visualization, customization and completion of many of the most challenging steps of cataract surgery:  Anterior capsulotomy  Lens fragmentation  All corneal incisions